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Items: 1 to 50 of 172

1.

Elderly apolipoprotein E‑/‑ mice with advanced atherosclerotic lesions in the aorta do not develop Alzheimer's disease-like pathologies.

Shnerb Ganor R, Harats D, Schiby G, Rosenblatt K, Lubitz I, Shaish A, Salomon O.

Mol Med Rep. 2018 Feb;17(2):2488-2492. doi: 10.3892/mmr.2017.8127. Epub 2017 Nov 21.

PMID:
29207114
2.

Interleukin-1α and Interleukin-1β play a central role in the pathogenesis of fulminant hepatic failure in mice.

Sultan M, Ben-Ari Z, Masoud R, Pappo O, Harats D, Kamari Y, Safran M.

PLoS One. 2017 Sep 27;12(9):e0184084. doi: 10.1371/journal.pone.0184084. eCollection 2017.

3.

Interleukin 1-alpha deficiency increases the expression of Follicle-stimulating hormone receptors in granulosa cells.

Uri-Belapolsky S, Miller I, Shaish A, Levi M, Harats D, Ninio-Many L, Kamari Y, Shalgi R.

Mol Reprod Dev. 2017 Jun;84(6):460-467. doi: 10.1002/mrd.22799. Epub 2017 Apr 17.

PMID:
28337831
4.

Molecular genetics of familial hypercholesterolemia in Israel-revisited.

Durst R, Ibe UK, Shpitzen S, Schurr D, Eliav O, Futema M, Whittall R, Szalat A, Meiner V, Knobler H, Gavish D, Henkin Y, Ellis A, Rubinstein A, Harats D, Bitzur R, Hershkovitz B, Humphries SE, Leitersdorf E.

Atherosclerosis. 2017 Feb;257:55-63. doi: 10.1016/j.atherosclerosis.2016.12.021. Epub 2016 Dec 18.

PMID:
28104544
5.

Cardiovascular health among two ethnic groups living in the same region: A population-based study.

Benderly M, Chetrit A, Murad H, Abu-Saad K, Gillon-Keren M, Rogowski O, Sela BA, Kanety H, Harats D, Atamna A, Alpert G, Goldbourt U, Kalter-Leibovici O.

Int J Cardiol. 2017 Feb 1;228:23-30. doi: 10.1016/j.ijcard.2016.11.079. Epub 2016 Nov 9.

PMID:
27863357
6.

Differential Effects of apoE4 and Activation of ABCA1 on Brain and Plasma Lipoproteins.

Boehm-Cagan A, Bar R, Harats D, Shaish A, Levkovitz H, Bielicki JK, Johansson JO, Michaelson DM.

PLoS One. 2016 Nov 8;11(11):e0166195. doi: 10.1371/journal.pone.0166195. eCollection 2016.

7.

9-cis β-Carotene Increased Cholesterol Efflux to HDL in Macrophages.

Bechor S, Zolberg Relevy N, Harari A, Almog T, Kamari Y, Ben-Amotz A, Harats D, Shaish A.

Nutrients. 2016 Jul 19;8(7). pii: E435. doi: 10.3390/nu8070435.

8.

Nifedipine Treatment for Hypertension is Associated with Enhanced Lipolytic Activity and Accelerated Clearance of Postprandial Lipemia.

Grosskopf I, Shaish A, Charach G, Harats D, Kamari Y.

Horm Metab Res. 2016 Apr;48(4):257-62. doi: 10.1055/s-0035-1565180. Epub 2016 Feb 5.

PMID:
26849821
9.

Factor XI Deficiency Protects Against Atherogenesis in Apolipoprotein E/Factor XI Double Knockout Mice.

Shnerb Ganor R, Harats D, Schiby G, Gailani D, Levkovitz H, Avivi C, Tamarin I, Shaish A, Salomon O.

Arterioscler Thromb Vasc Biol. 2016 Mar;36(3):475-81. doi: 10.1161/ATVBAHA.115.306954. Epub 2016 Jan 21.

10.

Thoracic Duct Narrowing-Innovative Technique Restraining Weight Gain in Rats.

Rosenzweig B, Barshack I, Harats D, Shaish A.

Obes Surg. 2015 Dec;25(12):2443-50. doi: 10.1007/s11695-015-1917-y.

PMID:
26446490
11.

[ISRAELI GUIDELINES FOR THE TREATMENT OF HYPERLIPIDEMIA - 2014 UPDATE].

Bitzur R, Rozenman Y, Vinker S, Dikerl D, Shemesh J, Lahad A, Gavishl D, Harats D, KnobLer H; Society for Research, Prevention and Treatment of Atherosclerosis, Israel; Israel Heart Society; Israel Association of Family Physicians; Israel Society of Internal Medicine.

Harefuah. 2015 May;154(5):330-3, 337-8. Hebrew.

PMID:
26168647
12.

Interleukin-1α deficiency attenuates endoplasmic reticulum stress-induced liver damage and CHOP expression in mice.

Kandel-Kfir M, Almog T, Shaish A, Shlomai G, Anafi L, Avivi C, Barshack I, Grosskopf I, Harats D, Kamari Y.

J Hepatol. 2015 Oct;63(4):926-33. doi: 10.1016/j.jhep.2015.05.012. Epub 2015 May 27.

PMID:
26022690
13.

The Effect of Klotho Treatment on Atherogenesis, Blood Pressure, and Metabolic Parameters in Experimental Rodent Models.

Kamari Y, Fingrut O, Shaish A, Almog T, Kandel-Kfir M, Harats D, Rubinek T, Wolf I.

Horm Metab Res. 2016 Mar;48(3):196-200. doi: 10.1055/s-0035-1549879. Epub 2015 May 7.

PMID:
25951321
14.

Vitamin A-deficient diet accelerated atherogenesis in apolipoprotein E(-/-) mice and dietary β-carotene prevents this consequence.

Relevy NZ, Harats D, Harari A, Ben-Amotz A, Bitzur R, Rühl R, Shaish A.

Biomed Res Int. 2015;2015:758723. doi: 10.1155/2015/758723. Epub 2015 Feb 23.

15.

Knockdown of interleukin-1α does not attenuate LPS-induced production of interleukin-1β in mouse macrophages.

Almog T, Kandel-Kfir M, Shaish A, Dissen M, Shlomai G, Voronov E, Apte RN, Harats D, Kamari Y.

Cytokine. 2015 May;73(1):138-43. doi: 10.1016/j.cyto.2015.01.029. Epub 2015 Mar 6.

PMID:
25748836
16.

The inhibition of macrophage foam cell formation by 9-cis β-carotene is driven by BCMO1 activity.

Zolberg Relevy N, Bechor S, Harari A, Ben-Amotz A, Kamari Y, Harats D, Shaish A.

PLoS One. 2015 Jan 28;10(1):e0115272. doi: 10.1371/journal.pone.0115272. eCollection 2015.

17.

Therapies targeting innate immunity for fighting inflammation in atherosclerosis.

Mendel I, Yacov N, Harats D, Breitbart E.

Curr Pharm Des. 2015;21(9):1185-95. Review.

PMID:
25312734
18.

Interleukin-1 deficiency prolongs ovarian lifespan in mice.

Uri-Belapolsky S, Shaish A, Eliyahu E, Grossman H, Levi M, Chuderland D, Ninio-Many L, Hasky N, Shashar D, Almog T, Kandel-Kfir M, Harats D, Shalgi R, Kamari Y.

Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12492-7. doi: 10.1073/pnas.1323955111. Epub 2014 Aug 11.

19.

Lack of interleukin-1α in Kupffer cells attenuates liver inflammation and expression of inflammatory cytokines in hypercholesterolaemic mice.

Olteanu S, Kandel-Kfir M, Shaish A, Almog T, Shemesh S, Barshack I, Apte RN, Harats D, Kamari Y.

Dig Liver Dis. 2014 May;46(5):433-9. doi: 10.1016/j.dld.2014.01.156. Epub 2014 Feb 26.

PMID:
24582082
20.

Low molecular weight heparin-induced increase in chylomicron-remnants clearance, is associated with decreased plasma TNF-α level and increased hepatic lipase activity.

Grosskopf I, Shaish A, Ray A, Harats D, Kamari Y.

Thromb Res. 2014 Apr;133(4):688-92. doi: 10.1016/j.thromres.2014.01.019. Epub 2014 Jan 21.

PMID:
24525311
21.

[Phytosterols: another way to reduce LDL cholesterol levels].

Bitzur R, Cohen H, Kamari Y, Harats D.

Harefuah. 2013 Dec;152(12):729-31, 751. Review. Hebrew.

PMID:
24482998
22.

Prevention of atherosclerosis progression by 9-cis-β-carotene rich alga Dunaliella in apoE-deficient mice.

Harari A, Abecassis R, Relevi N, Levi Z, Ben-Amotz A, Kamari Y, Harats D, Shaish A.

Biomed Res Int. 2013;2013:169517. doi: 10.1155/2013/169517. Epub 2013 Sep 23.

23.

VB-201, an oxidized phospholipid small molecule, inhibits CD14- and Toll-like receptor-2-dependent innate cell activation and constrains atherosclerosis.

Mendel I, Feige E, Yacov N, Salem Y, Levi I, Propheta-Meiran O, Shoham A, Ishai E, George J, Harats D, Breitbart E.

Clin Exp Immunol. 2014 Jan;175(1):126-37. doi: 10.1111/cei.12212.

24.

Adenoviral transduction of human acid sphingomyelinase into neo-angiogenic endothelium radiosensitizes tumor cure.

Stancevic B, Varda-Bloom N, Cheng J, Fuller JD, Rotolo JA, García-Barros M, Feldman R, Rao S, Weichselbaum RR, Harats D, Haimovitz-Friedman A, Fuks Z, Sadelain M, Kolesnick R.

PLoS One. 2013 Aug 2;8(8):e69025. doi: 10.1371/journal.pone.0069025. Print 2013.

25.

Intolerance to statins: mechanisms and management.

Bitzur R, Cohen H, Kamari Y, Harats D.

Diabetes Care. 2013 Aug;36 Suppl 2:S325-30. doi: 10.2337/dcS13-2038. Review. No abstract available.

26.

Inhibition of monocyte chemotaxis by VB-201, a small molecule lecinoxoid, hinders atherosclerosis development in ApoE⁻/⁻ mice.

Feige E, Yacov N, Salem Y, Levi I, Mendel I, Propheta-Meiran O, Shoham A, Hait-Darshan R, Polonsky O, George J, Harats D, Breitbart E.

Atherosclerosis. 2013 Aug;229(2):430-9. doi: 10.1016/j.atherosclerosis.2013.06.005. Epub 2013 Jun 21.

27.

Treatment with 9-cis β-carotene-rich powder in patients with retinitis pigmentosa: a randomized crossover trial.

Rotenstreich Y, Belkin M, Sadetzki S, Chetrit A, Ferman-Attar G, Sher I, Harari A, Shaish A, Harats D.

JAMA Ophthalmol. 2013 Aug;131(8):985-92.

PMID:
23700011
28.

Phase I dose-escalation study of VB-111, an antiangiogenic virotherapy, in patients with advanced solid tumors.

Brenner AJ, Cohen YC, Breitbart E, Bangio L, Sarantopoulos J, Giles FJ, Borden EC, Harats D, Triozzi PL.

Clin Cancer Res. 2013 Jul 15;19(14):3996-4007. doi: 10.1158/1078-0432.CCR-12-2079. Epub 2013 Apr 15.

29.

9-cis-rich β-carotene powder of the alga Dunaliella reduces the severity of chronic plaque psoriasis: a randomized, double-blind, placebo-controlled clinical trial.

Greenberger S, Harats D, Salameh F, Lubish T, Harari A, Trau H, Shaish A.

J Am Coll Nutr. 2012 Oct;31(5):320-6.

PMID:
23529989
30.

[Prevention and treatment of atherosclerosis and cardiovascular diseases].

Knobler H, Bitzur R, Gavish D, Rubinstein A, Henkin Y, Chajek-Shaul T, Harats D.

Harefuah. 2012 May;151(5):281-8, 319, 318. Hebrew.

PMID:
22844732
31.

Apolipoprotein A-V modulates multiple atherogenic mechanisms in a mouse model of disturbed clearance of triglyceride-rich lipoproteins.

Grosskopf I, Shaish A, Afek A, Shemesh S, Harats D, Kamari Y.

Atherosclerosis. 2012 Sep;224(1):75-83. doi: 10.1016/j.atherosclerosis.2012.04.011. Epub 2012 May 29.

PMID:
22809445
32.

Antitumor Activity of VB-111, a Novel Antiangiogenic Virotherapeutic, in Thyroid Cancer Xenograft Mouse Models.

Reddi HV, Madde P, Cohen YC, Bangio L, Breitbart E, Harats D, Bible KC, Eberhardt NL.

Genes Cancer. 2011 Oct;2(10):993-5. doi: 10.1177/1947601912437933.

33.

Low-dose calcitriol decreases aortic renin, blood pressure, and atherosclerosis in apoe-null mice.

Ish-Shalom M, Sack J, Vechoropoulos M, Shaish A, Entin-Meer M, Kamari Y, Maysel-Auslender S, Keren G, Harats D, Stern N, Tordjman K.

J Atheroscler Thromb. 2012;19(5):422-34. Epub 2012 Apr 16.

34.

Alteration of lipids and the transcription of lipid-related genes in myelodysplastic syndromes via a TP53-related pathway.

Ellis MH, Baraf L, Shaish A, Har-Zahav A, Harats D, Ashur-Fabian O.

Exp Hematol. 2012 Jul;40(7):540-547.e1. doi: 10.1016/j.exphem.2012.02.003. Epub 2012 Feb 27.

PMID:
22381680
35.

Interleukin-1 receptor type-1 in non-hematopoietic cells is the target for the pro-atherogenic effects of interleukin-1 in apoE-deficient mice.

Shemesh S, Kamari Y, Shaish A, Olteanu S, Kandel-Kfir M, Almog T, Grosskopf I, Apte RN, Harats D.

Atherosclerosis. 2012 Jun;222(2):329-36. doi: 10.1016/j.atherosclerosis.2011.12.010. Epub 2011 Dec 17.

PMID:
22236482
36.

Brachial artery endothelial function predicts platelet function in control subjects and in patients with acute myocardial infarction.

Shechter M, Shechter A, Hod H, Fefer P, Shenkman B, Koren-Morag N, Feinberg MS, Harats D, Ami Sela B, Savion N, Varon D, Matetzky S.

Platelets. 2012;23(3):202-10. doi: 10.3109/09537104.2011.604805. Epub 2011 Aug 9.

PMID:
21824040
37.

Metabolically regulated endoplasmic reticulum-associated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: evidence for requirement of a geranylgeranylated protein.

Leichner GS, Avner R, Harats D, Roitelman J.

J Biol Chem. 2011 Sep 16;286(37):32150-61. doi: 10.1074/jbc.M111.278036. Epub 2011 Jul 21.

38.

Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice.

Kamari Y, Shaish A, Vax E, Shemesh S, Kandel-Kfir M, Arbel Y, Olteanu S, Barshack I, Dotan S, Voronov E, Dinarello CA, Apte RN, Harats D.

J Hepatol. 2011 Nov;55(5):1086-94. doi: 10.1016/j.jhep.2011.01.048. Epub 2011 Feb 24.

39.

Impact of acute caffeine ingestion on endothelial function in subjects with and without coronary artery disease.

Shechter M, Shalmon G, Scheinowitz M, Koren-Morag N, Feinberg MS, Harats D, Sela BA, Sharabi Y, Chouraqui P.

Am J Cardiol. 2011 May 1;107(9):1255-61. doi: 10.1016/j.amjcard.2010.12.035. Epub 2011 Feb 23.

PMID:
21349479
40.

Serum apolipoproteins C-I and C-III are reduced in stomach cancer patients: results from MALDI-based peptidome and immuno-based clinical assays.

Cohen M, Yossef R, Erez T, Kugel A, Welt M, Karpasas MM, Bones J, Rudd PM, Taieb J, Boissin H, Harats D, Noy K, Tekoah Y, Lichtenstein RG, Rubin E, Porgador A.

PLoS One. 2011 Jan 18;6(1):e14540. doi: 10.1371/journal.pone.0014540.

41.

Reduced atherosclerosis and inflammatory cytokines in apolipoprotein-E-deficient mice lacking bone marrow-derived interleukin-1α.

Kamari Y, Shaish A, Shemesh S, Vax E, Grosskopf I, Dotan S, White M, Voronov E, Dinarello CA, Apte RN, Harats D.

Biochem Biophys Res Commun. 2011 Feb 11;405(2):197-203. doi: 10.1016/j.bbrc.2011.01.008. Epub 2011 Jan 8.

PMID:
21219852
42.

Fatty acid bile acid conjugate inhibits hepatic stearoyl coenzyme A desaturase and is non-atherogenic.

Leikin-Frenkel A, Gonen A, Shaish A, Goldiner I, Leikin-Gobbi D, Konikoff FM, Harats D, Gilat T.

Arch Med Res. 2010 Aug;41(6):397-404. doi: 10.1016/j.arcmed.2010.09.001.

PMID:
21044742
43.

Effects of hypoxia-inducible factor-1alpha overexpression in pregnant mice: possible implications for preeclampsia and intrauterine growth restriction.

Tal R, Shaish A, Barshack I, Polak-Charcon S, Afek A, Volkov A, Feldman B, Avivi C, Harats D.

Am J Pathol. 2010 Dec;177(6):2950-62. doi: 10.2353/ajpath.2010.090800. Epub 2010 Oct 15.

44.

apoB and apobec1, two genes key to lipid metabolism, are transcriptionally regulated by p53.

Ashur-Fabian O, Har-Zahav A, Shaish A, Wiener Amram H, Margalit O, Weizer-Stern O, Dominissini D, Harats D, Amariglio N, Rechavi G.

Cell Cycle. 2010 Sep 15;9(18):3761-70. Epub 2010 Sep 12.

PMID:
20890106
45.

Modified phospholipids as anti-inflammatory compounds.

Feige E, Mendel I, George J, Yacov N, Harats D.

Curr Opin Lipidol. 2010 Dec;21(6):525-9. doi: 10.1097/MOL.0b013e32833f2fcb. Review.

PMID:
20827191
46.

Deficiency of antigen-presenting cell invariant chain reduces atherosclerosis in mice.

Sun J, Hartvigsen K, Chou MY, Zhang Y, Sukhova GK, Zhang J, Lopez-Ilasaca M, Diehl CJ, Yakov N, Harats D, George J, Witztum JL, Libby P, Ploegh H, Shi GP.

Circulation. 2010 Aug 24;122(8):808-20. doi: 10.1161/CIRCULATIONAHA.109.891887. Epub 2010 Aug 9.

47.

The metabolic effects of omega-3 plant sterol esters in mixed hyperlipidemic subjects.

Bitzur R, Cohen H, Cohen T, Dror TW, Herzog Y, Lifshitz Y, Lubish T, Harats D, Rubinstein A.

Cardiovasc Drugs Ther. 2010 Dec;24(5-6):429-37. doi: 10.1007/s10557-010-6249-5.

PMID:
20617456
48.

Conservative treatment of L-asparaginase-associated lipid abnormalities in children with acute lymphoblastic leukemia.

Cohen H, Bielorai B, Harats D, Toren A, Pinhas-Hamiel O.

Pediatr Blood Cancer. 2010 May;54(5):703-6. doi: 10.1002/pbc.22305.

PMID:
20063421
49.

Treatment of a retinal dystrophy, fundus albipunctatus, with oral 9-cis-{beta}-carotene.

Rotenstreich Y, Harats D, Shaish A, Pras E, Belkin M.

Br J Ophthalmol. 2010 May;94(5):616-21. doi: 10.1136/bjo.2009.167049. Epub 2009 Dec 2.

PMID:
19955196
50.

Should all diabetic patients be treated with a statin?

Kamari Y, Bitzur R, Cohen H, Shaish A, Harats D.

Diabetes Care. 2009 Nov;32 Suppl 2:S378-83. doi: 10.2337/dc09-S344. Review. No abstract available.

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