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Items: 11


Homology sensing via non-linear amplification of sequence-dependent pausing by RecQ helicase.

Seol Y, Harami GM, Kovács M, Neuman KC.

Elife. 2019 Aug 29;8. pii: e45909. doi: 10.7554/eLife.45909.


Human RAD51 rapidly forms intrinsically dynamic nucleoprotein filaments modulated by nucleotide binding state.

Špírek M, Mlcoušková J, Belán O, Gyimesi M, Harami GM, Molnár E, Novacek J, Kovács M, Krejci L.

Nucleic Acids Res. 2018 May 4;46(8):3967-3980. doi: 10.1093/nar/gky111.


Functional fine-tuning between bacterial DNA recombination initiation and quality control systems.

Ferencziová V, Harami GM, Németh JB, Vellai T, Kovács M.

PLoS One. 2018 Feb 22;13(2):e0192483. doi: 10.1371/journal.pone.0192483. eCollection 2018.


RecQ helicase triggers a binding mode change in the SSB-DNA complex to efficiently initiate DNA unwinding.

Mills M, Harami GM, Seol Y, Gyimesi M, Martina M, Kovács ZJ, Kovács M, Neuman KC.

Nucleic Acids Res. 2017 Nov 16;45(20):11878-11890. doi: 10.1093/nar/gkx939.


Shuttling along DNA and directed processing of D-loops by RecQ helicase support quality control of homologous recombination.

Harami GM, Seol Y, In J, Ferencziová V, Martina M, Gyimesi M, Sarlós K, Kovács ZJ, Nagy NT, Sun Y, Vellai T, Neuman KC, Kovács M.

Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E466-E475. doi: 10.1073/pnas.1615439114. Epub 2017 Jan 9.


Recent adaptations of fluorescence techniques for the determination of mechanistic parameters of helicases and translocases.

Gyimesi M, Harami GM, Kocsis ZS, Kovács M.

Methods. 2016 Oct 1;108:24-39. doi: 10.1016/j.ymeth.2016.04.028. Epub 2016 Apr 29.


A nucleotide-dependent and HRDC domain-dependent structural transition in DNA-bound RecQ helicase.

Kocsis ZS, Sarlós K, Harami GM, Martina M, Kovács M.

J Biol Chem. 2014 Feb 28;289(9):5938-49. doi: 10.1074/jbc.M113.530741. Epub 2014 Jan 8.


From keys to bulldozers: expanding roles for winged helix domains in nucleic-acid-binding proteins.

Harami GM, Gyimesi M, Kovács M.

Trends Biochem Sci. 2013 Jul;38(7):364-71. doi: 10.1016/j.tibs.2013.04.006. Epub 2013 Jun 11. Review.


A subdomain interaction at the base of the lever allosterically tunes the mechanochemical mechanism of myosin 5a.

Nagy NT, Chakraborty S, Harami GM, Sellers JR, Sakamoto T, Kovács M.

PLoS One. 2013 May 1;8(5):e62640. doi: 10.1371/journal.pone.0062640. Print 2013.


Complex activities of the human Bloom's syndrome helicase are encoded in a core region comprising the RecA and Zn-binding domains.

Gyimesi M, Harami GM, Sarlós K, Hazai E, Bikádi Z, Kovács M.

Nucleic Acids Res. 2012 May;40(9):3952-63. doi: 10.1093/nar/gks008. Epub 2012 Jan 16.

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