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Items: 18

1.

CYP3A4*16 and CYP3A4*18 alleles found in East Asians exhibit differential catalytic activities for seven CYP3A4 substrate drugs.

Maekawa K, Harakawa N, Yoshimura T, Kim SR, Fujimura Y, Aohara F, Sai K, Katori N, Tohkin M, Naito M, Hasegawa R, Okuda H, Sawada J, Niwa T, Saito Y.

Drug Metab Dispos. 2010 Dec;38(12):2100-4. doi: 10.1124/dmd.110.034140. Epub 2010 Sep 16.

PMID:
20847137
2.

Substrate-dependent functional alterations of seven CYP2C9 variants found in Japanese subjects.

Maekawa K, Harakawa N, Sugiyama E, Tohkin M, Kim SR, Kaniwa N, Katori N, Hasegawa R, Yasuda K, Kamide K, Miyata T, Saito Y, Sawada J.

Drug Metab Dispos. 2009 Sep;37(9):1895-903. doi: 10.1124/dmd.109.027003. Epub 2009 Jun 18.

PMID:
19541829
3.

P-selectin glycoprotein ligand-1 mediates L-selectin-independent leukocyte rolling in high endothelial venules of peripheral lymph nodes.

Harakawa N, Shigeta A, Wato M, Merrill-Skoloff G, Furie BC, Furie B, Okazaki T, Domae N, Miyasaka M, Hirata T.

Int Immunol. 2007 Mar;19(3):321-9. Epub 2007 Jan 30.

PMID:
17267415
4.

Matrix metalloproteinase-1 produced by human CXCL12-stimulated natural killer cells.

Goda S, Inoue H, Umehara H, Miyaji M, Nagano Y, Harakawa N, Imai H, Lee P, Macarthy JB, Ikeo T, Domae N, Shimizu Y, Iida J.

Am J Pathol. 2006 Aug;169(2):445-58.

5.
6.

A direct binding site for Grb2 contributes to transformation and leukemogenesis by the Tel-Abl (ETV6-Abl) tyrosine kinase.

Million RP, Harakawa N, Roumiantsev S, Varticovski L, Van Etten RA.

Mol Cell Biol. 2004 Jun;24(11):4685-95.

7.

AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations.

Yuan Y, Zhou L, Miyamoto T, Iwasaki H, Harakawa N, Hetherington CJ, Burel SA, Lagasse E, Weissman IL, Akashi K, Zhang DE.

Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10398-403.

8.

Dichotomy of AML1-ETO functions: growth arrest versus block of differentiation.

Burel SA, Harakawa N, Zhou L, Pabst T, Tenen DG, Zhang DE.

Mol Cell Biol. 2001 Aug;21(16):5577-90.

9.

AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.

Pabst T, Mueller BU, Harakawa N, Schoch C, Haferlach T, Behre G, Hiddemann W, Zhang DE, Tenen DG.

Nat Med. 2001 Apr;7(4):444-51.

PMID:
11283671
10.

Analysis of the role of AML1-ETO in leukemogenesis, using an inducible transgenic mouse model.

Rhoades KL, Hetherington CJ, Harakawa N, Yergeau DA, Zhou L, Liu LQ, Little MT, Tenen DG, Zhang DE.

Blood. 2000 Sep 15;96(6):2108-15.

PMID:
10979955
11.

Down-regulation of CXCR2 expression on human polymorphonuclear leukocytes by TNF-alpha.

Asagoe K, Yamamoto K, Takahashi A, Suzuki K, Maeda A, Nohgawa M, Harakawa N, Takano K, Mukaida N, Matsushima K, Okuma M, Sasada M.

J Immunol. 1998 May 1;160(9):4518-25.

12.

Leukotriene B4-activated human endothelial cells promote transendothelial neutrophil migration.

Nohgawa M, Sasada M, Maeda A, Asagoe K, Harakawa N, Takano K, Yamamoto K, Okuma M.

J Leukoc Biol. 1997 Aug;62(2):203-9.

PMID:
9261334
13.

Demonstration of functionally distinct human polymorphonuclear leukocyte fractions by simultaneous measurement of phagocytosis and oxygen radical generation.

Takano K, Sasada M, Harakawa N, Nogawa M, Asagoe K, Yamamoto K, Okuma M.

Int J Hematol. 1997 Jul;66(1):69-78.

PMID:
9220662
14.

Random migration of polymorphonuclear leukocytes induced by GM-CSF involving a signal transduction pathway different from that of fMLP.

Harakawa N, Sasada M, Maeda A, Asagoe K, Nohgawa M, Takano K, Matsuda Y, Yamamoto K, Okuma M.

J Leukoc Biol. 1997 Apr;61(4):500-6.

PMID:
9103237
15.

Pharmacokinetics of human activated protein C. 1st communication: plasma concentration and excretion of a lyophilized purified human activated protein C after intravenous administration in the mouse and the rabbit.

Ishii S, Mochizuki T, Nagao T, Sugiki S, Kudo S, Harakawa N, Taniguchi K, Igarashi Y, Kondo S, Kiyoki M.

Arzneimittelforschung. 1995 May;45(5):636-44.

PMID:
7612068
16.

[Complete remission in acute myeloblastic leukemia (M0) after treatment with rhG-CSF].

Maeda A, Yoshinaga N, Hirata H, Asagoe K, Nohgawa M, Takano K, Harakawa N, Nakabo Y, Takahashi A, Yamamoto K, et al.

Rinsho Ketsueki. 1995 Jan;36(1):45-9. Japanese.

PMID:
7536276
17.

Mechanism of leukemic cell lysis by activated human macrophages: leukemic cells can be lysed without direct contact.

Nakabo Y, Harakawa N, Yamamoto K, Okuma M, Uno K, Sasada M.

Int J Hematol. 1994 Jul;60(1):51-7.

PMID:
7919238
18.

Leukemic cell lysis by activated human macrophages: significance of membrane-associated tumor necrosis factor.

Nakabo Y, Harakawa N, Yamamoto K, Okuma M, Uno K, Sasada M.

Jpn J Cancer Res. 1993 Nov;84(11):1174-80.

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