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Impact of a systematic education model for palliative care in cancer.

Uchida M, Hada M, Yamada M, Inma D, Ariyoshi S, Aoki K, Inoue S, Shimazoe T, Mitsuiki K, Haraguchi T.

Pharmazie. 2019 Aug 1;74(8):499-504. doi: 10.1691/ph.2019.9417.


Effect of Hydrothermal Treatment with Distilled Water on Titanium Alloy for Epithelial Cellular Attachment.

Sakamoto Y, Ayukawa Y, Furuhashi A, Kamo M, Ikeda J, Atsuta I, Haraguchi T, Koyano K.

Materials (Basel). 2019 Aug 27;12(17). pii: E2748. doi: 10.3390/ma12172748.


Effect of post-osseointegration loading magnitude on the dynamics of peri-implant bone: a finite element analysis and in vivo study.

Matsuzaki T, Ayukawa Y, Matsushita Y, Sakai N, Matsuzaki M, Masuzaki T, Haraguchi T, Ogino Y, Koyano K.

J Prosthodont Res. 2019 Oct;63(4):453-459. doi: 10.1016/j.jpor.2018.10.009. Epub 2019 Jul 24.


A new strategy for taste masking on bitter drug by other combined drug in fixed-dose combination: bitterness of Amlodipine besylate could be masked efficiently by Valsartan.

Kojima H, Nakamura S, Haraguchi T, Yoshida M, Habara M, Ikezaki H, Uchida T.

J Pharm Pharmacol. 2019 Sep;71(9):1384-1392. doi: 10.1111/jphp.13134. Epub 2019 Jul 5.


Investigation by DFT Methods of the Damage of Human Serum Albumin Including Amino Acid Derivative Schiff Base Zn(II) Complexes by IR-FEL Irradiation.

Onami Y, Koya R, Kawasaki T, Aizawa H, Nakagame R, Miyagawa Y, Haraguchi T, Akitsu T, Tsukiyama K, Palafox MA.

Int J Mol Sci. 2019 Jun 11;20(11). pii: E2846. doi: 10.3390/ijms20112846.


Nuclear formation induced by DNA-conjugated beads in living fertilised mouse egg.

Suzuki Y, Bilir Ş, Hatano Y, Fukuda T, Mashiko D, Kobayashi S, Hiraoka Y, Haraguchi T, Yamagata K.

Sci Rep. 2019 Jun 11;9(1):8461. doi: 10.1038/s41598-019-44941-6.


Asymmetrical localization of Nup107-160 subcomplex components within the nuclear pore complex in fission yeast.

Asakawa H, Kojidani T, Yang HJ, Ohtsuki C, Osakada H, Matsuda A, Iwamoto M, Chikashige Y, Nagao K, Obuse C, Hiraoka Y, Haraguchi T.

PLoS Genet. 2019 Jun 6;15(6):e1008061. doi: 10.1371/journal.pgen.1008061. eCollection 2019 Jun.


Histone H2A insufficiency causes chromosomal segregation defects due to anaphase chromosome bridge formation at rDNA repeats in fission yeast.

Yamamoto TG, Ding DQ, Nagahama Y, Chikashige Y, Haraguchi T, Hiraoka Y.

Sci Rep. 2019 May 9;9(1):7159. doi: 10.1038/s41598-019-43633-5.


Bitterness-Masking Effects of Different Beverages on Zopiclone and Eszopiclone Tablets.

Yoshida M, Kojima H, Uda A, Haraguchi T, Ozeki M, Kawasaki I, Yamamoto K, Yano I, Hirai M, Uchida T.

Chem Pharm Bull (Tokyo). 2019;67(5):404-409. doi: 10.1248/cpb.c18-00502.


The very-long-chain fatty acid elongase Elo2 rescues lethal defects associated with loss of the nuclear barrier function in fission yeast cells.

Kinugasa Y, Hirano Y, Sawai M, Ohno Y, Shindo T, Asakawa H, Chikashige Y, Shibata S, Kihara A, Haraguchi T, Hiraoka Y.

J Cell Sci. 2019 May 15;132(10). pii: jcs229021. doi: 10.1242/jcs.229021.


Visualization of secretory cargo transport within the Golgi apparatus.

Kurokawa K, Osakada H, Kojidani T, Waga M, Suda Y, Asakawa H, Haraguchi T, Nakano A.

J Cell Biol. 2019 May 6;218(5):1602-1618. doi: 10.1083/jcb.201807194. Epub 2019 Mar 11.


Roles of Nup133, Nup153 and membrane fenestrations in assembly of the nuclear pore complex at the end of mitosis.

Bilir Ş, Kojidani T, Mori C, Osakada H, Kobayashi S, Koujin T, Hiraoka Y, Haraguchi T.

Genes Cells. 2019 May;24(5):338-353. doi: 10.1111/gtc.12677. Epub 2019 Mar 22.


Co-crystallization of 3,5-di-nitro-benzoic acid with two anti-psychotic agents: a simple 1:1 salt with trihexyphenidyl and a 1:2 acid salt containing a very short O-H⋯O hydrogen bond with chlorprothixene.

Shaibah MAE, Yathirajan HS, Rathore RS, Furuya T, Haraguchi T, Akitsu T, Glidewell C.

Acta Crystallogr E Crystallogr Commun. 2019 Jan 31;75(Pt 2):292-298. doi: 10.1107/S2056989019001385. eCollection 2019 Feb 1.


Three closely related 1-[(1,3-benzodioxol-5-yl)methyl]-4-(halobenzo-yl)piperazines: similar mol-ecular structures but different inter-molecular inter-actions.

Mahesha N, Sagar BK, Yathirajan HS, Furuya T, Haraguchi T, Akitsu T, Glidewell C.

Acta Crystallogr E Crystallogr Commun. 2019 Jan 11;75(Pt 2):202-207. doi: 10.1107/S2056989019000458. eCollection 2019 Feb 1.


Regioselective α-Peptide Bond Formation Through the Oxidation of Amino Thioacids.

Okamoto R, Haraguchi T, Nomura K, Maki Y, Izumi M, Kajihara Y.

Biochemistry. 2019 Mar 26;58(12):1672-1678. doi: 10.1021/acs.biochem.8b01239. Epub 2019 Mar 8.


Agenesis of hepatic lobes in a dog.

Oishi Y, Tani K, Itamoto K, Haraguchi T, Taura Y.

Open Vet J. 2018;8(4):485-488. doi: 10.4314/ovj.v8i4.21. Epub 2018 Dec 27.


Young adult-onset, very slowly progressive cognitive decline with spastic paraparesis in Alzheimer's disease with cotton wool plaques due to a novel presenilin1 G417S mutation.

Miki T, Yokota O, Haraguchi T, Ikeuchi T, Zhu B, Takenoshita S, Terada S, Yamada N.

Acta Neuropathol Commun. 2019 Feb 12;7(1):19. doi: 10.1186/s40478-019-0672-z. No abstract available.


Preparation and Characterization of Itraconazole- or Miconazole-Loaded PLGA Microspheres.

Matsuura K, Kojima H, Haraguchi T, Yoshida M, Suzuki S, Suzuki T, Ando S, Uchida T.

Chem Pharm Bull (Tokyo). 2019;67(2):106-111. doi: 10.1248/cpb.c18-00614.


Functional Diversity of Class XI Myosins in Arabidopsis thaliana.

Haraguchi T, Ito K, Duan Z, Rula S, Takahashi K, Shibuya Y, Hagino N, Miyatake Y, Nakano A, Tominaga M.

Plant Cell Physiol. 2018 Nov 1;59(11):2268-2277. doi: 10.1093/pcp/pcy147.


Author Correction: The role of the SWI/SNF chromatin remodeling complex in maintaining the stemness of glioma initiating cells.

Hiramatsu H, Kobayashi K, Kobayashi K, Haraguchi T, Ino Y, Todo T, Iba H.

Sci Rep. 2018 Oct 25;8(1):16079. doi: 10.1038/s41598-018-31444-z.


Crystal structure of 3,6-dihy-droxy-4,5-di-methyl-benzene-1,2-dicarbaldehyde.

Yamazaki S, Nishiyama K, Yagi S, Haraguchi T, Akitsu T.

Acta Crystallogr E Crystallogr Commun. 2018 Sep 14;74(Pt 10):1424-1426. doi: 10.1107/S2056989018012495. eCollection 2018 Oct 1.


Crystal structure of (E)-3-[(2,6-di-methyl-phen-yl)diazen-yl]-7-methyl-1H-indazole.

Yagi S, Haraguchi T, Akitsu T.

Acta Crystallogr E Crystallogr Commun. 2018 Sep 14;74(Pt 10):1421-1423. doi: 10.1107/S2056989018012483. eCollection 2018 Oct 1.


Treatment for in-stent restenosis requiring rotational atherectomy.

Hachinohe D, Kashima Y, Hirata K, Kanno D, Kobayashi K, Kaneko U, Sugie T, Tadano Y, Watanabe T, Shitan H, Haraguchi T, Enomoto M, Sato K, Fujita T.

J Interv Cardiol. 2018 Dec;31(6):747-754. doi: 10.1111/joic.12558. Epub 2018 Sep 2.


Dietary Sparassis crispa Reduces Body Fat Mass and Hepatic Lipid Levels by Enhancing Energy Expenditure and Suppressing Lipogenesis in Rats.

Takeyama A, Nagata Y, Shirouchi B, Nonaka C, Aoki H, Haraguchi T, Sato M, Tamaya K, Yamamoto H, Tanaka K.

J Oleo Sci. 2018 Sep 1;67(9):1137-1147. doi: 10.5650/jos.ess18043. Epub 2018 Aug 14.


Clinicopathological value of programmed cell death 1 (PD-1) and programmed cell death ligand 1 (PD-L1) expression in synovium of patients with rheumatoid arthritis.

Matsuda K, Miyoshi H, Hiraoka K, Hamada T, Yoshida S, Ishibashi Y, Haraguchi T, Shiba N, Ohshima K.

Clin Exp Med. 2018 Nov;18(4):487-494. doi: 10.1007/s10238-018-0515-4. Epub 2018 Jun 30.


Thrombectomy Using Myocardial Biopsy Forceps in Acute Limb Ischemia Patients.

Shimada T, Urasawa K, Haraguchi T, Kitani S, Tan M, Koshida R, Igarashi Y, Sato K.

J Vasc Interv Radiol. 2018 Aug;29(8):1174-1179. doi: 10.1016/j.jvir.2018.02.021. Epub 2018 Jun 7.


Nuclear localization signal targeting to macronucleus and micronucleus in binucleated ciliate Tetrahymena thermophila.

Iwamoto M, Mori C, Osakada H, Koujin T, Hiraoka Y, Haraguchi T.

Genes Cells. 2018 Jul;23(7):568-579. doi: 10.1111/gtc.12602. Epub 2018 Jun 8.


Solubility Improvement of Benexate through Salt Formation Using Artificial Sweetener.

Dwichandra Putra O, Umeda D, Fujita E, Haraguchi T, Uchida T, Yonemochi E, Uekusa H.

Pharmaceutics. 2018 May 26;10(2). pii: E64. doi: 10.3390/pharmaceutics10020064.


Exportin Crm1 is repurposed as a docking protein to generate microtubule organizing centers at the nuclear pore.

Bao XX, Spanos C, Kojidani T, Lynch EM, Rappsilber J, Hiraoka Y, Haraguchi T, Sawin KE.

Elife. 2018 May 29;7. pii: e33465. doi: 10.7554/eLife.33465.


Using food network unfolding to evaluate food-web complexity in terms of biodiversity: theory and applications.

Kato Y, Kondoh M, Ishikawa NF, Togashi H, Kohmatsu Y, Yoshimura M, Yoshimizu C, Haraguchi TF, Osada Y, Ohte N, Tokuchi N, Okuda N, Miki T, Tayasu I.

Ecol Lett. 2018 Jul;21(7):1065-1074. doi: 10.1111/ele.12973. Epub 2018 May 17.


Accurate and fiducial-marker-free correction for three-dimensional chromatic shift in biological fluorescence microscopy.

Matsuda A, Schermelleh L, Hirano Y, Haraguchi T, Hiraoka Y.

Sci Rep. 2018 May 15;8(1):7583. doi: 10.1038/s41598-018-25922-7.


Author Correction: Lateral attachment of kinetochores to microtubules is enriched in prometaphase rosette and facilitates chromosome alignment and bi-orientation establishment.

Itoh G, Ikeda M, Iemura K, Amin MA, Kuriyama S, Tanaka M, Mizuno N, Osakada H, Haraguchi T, Tanaka K.

Sci Rep. 2018 Apr 30;8(1):7003. doi: 10.1038/s41598-018-25175-4.


A novel presenilin 1 mutation (Leu418Trp) associated with spasticity, parkinsonism, and white matter lesion in a dominant Alzheimer's family.

Takahashi Y, Ohta Y, Sasaki R, Tadokoro K, Sato K, Shang J, Takemoto M, Hishikawa N, Yamashita T, Haraguchi T, Ikeuchi T, Abe K.

J Neurol Sci. 2018 Apr 15;387:166-169. doi: 10.1016/j.jns.2018.01.006. Epub 2018 Jan 5. No abstract available.


p62/SQSTM1 promotes rapid ubiquitin conjugation to target proteins after endosome rupture during xenophagy.

Tsuchiya M, Ogawa H, Koujin T, Mori C, Osakada H, Kobayashi S, Hiraoka Y, Haraguchi T.

FEBS Open Bio. 2018 Feb 7;8(3):470-480. doi: 10.1002/2211-5463.12385. eCollection 2018 Mar.


Lateral attachment of kinetochores to microtubules is enriched in prometaphase rosette and facilitates chromosome alignment and bi-orientation establishment.

Itoh G, Ikeda M, Iemura K, Amin MA, Kuriyama S, Tanaka M, Mizuno N, Osakada H, Haraguchi T, Tanaka K.

Sci Rep. 2018 Mar 1;8(1):3888. doi: 10.1038/s41598-018-22164-5. Erratum in: Sci Rep. 2018 Apr 30;8(1):7003.


Remodeling the Specificity of an Endosomal CORVET Tether Underlies Formation of Regulated Secretory Vesicles in the Ciliate Tetrahymena thermophila.

Sparvoli D, Richardson E, Osakada H, Lan X, Iwamoto M, Bowman GR, Kontur C, Bourland WA, Lynn DH, Pritchard JK, Haraguchi T, Dacks JB, Turkewitz AP.

Curr Biol. 2018 Mar 5;28(5):697-710.e13. doi: 10.1016/j.cub.2018.01.047. Epub 2018 Feb 22.


Archaeological application of airborne LiDAR to examine social changes in the Ceibal region of the Maya lowlands.

Inomata T, Triadan D, Pinzón F, Burham M, Ranchos JL, Aoyama K, Haraguchi T.

PLoS One. 2018 Feb 21;13(2):e0191619. doi: 10.1371/journal.pone.0191619. eCollection 2018.


Comparison of Angiographic Dissection Patterns Caused by Long vs Short Balloons During Balloon Angioplasty of Chronic Femoropopliteal Occlusions.

Tan M, Urasawa K, Koshida R, Haraguchi T, Kitani S, Igarashi Y, Sato K.

J Endovasc Ther. 2018 Apr;25(2):192-200. doi: 10.1177/1526602818756610. Epub 2018 Feb 11.


Estimation of GFP-Nucleoporin Amount Based on Fluorescence Microscopy.

Asakawa H, Hiraoka Y, Haraguchi T.

Methods Mol Biol. 2018;1721:105-115. doi: 10.1007/978-1-4939-7546-4_10. Review.


The Utility of the Artificial Taste Sensor in Evaluating the Bitterness of Drugs: Correlation with Responses of Human TASTE2 Receptors (hTAS2Rs).

Haraguchi T, Uchida T, Yoshida M, Kojima H, Habara M, Ikezaki H.

Chem Pharm Bull (Tokyo). 2018;66(1):71-77. doi: 10.1248/cpb.c17-00619.


Lem2 is retained at the nuclear envelope through its interaction with Bqt4 in fission yeast.

Hirano Y, Kinugasa Y, Asakawa H, Chikashige Y, Obuse C, Haraguchi T, Hiraoka Y.

Genes Cells. 2018 Mar;23(3):122-135. doi: 10.1111/gtc.12557. Epub 2018 Jan 2.


Measurement of enzymatic and motile activities of Arabidopsis myosins by using Arabidopsis actins.

Rula S, Suwa T, Kijima ST, Haraguchi T, Wakatsuki S, Sato N, Duan Z, Tominaga M, Uyeda TQP, Ito K.

Biochem Biophys Res Commun. 2018 Jan 15;495(3):2145-2151. doi: 10.1016/j.bbrc.2017.12.071. Epub 2017 Dec 14.


Clinicopathological and prognostic value of transforming acidic coiled-coil-containing protein 3 (TACC3) expression in soft tissue sarcomas.

Matsuda K, Miyoshi H, Hiraoka K, Yokoyama S, Haraguchi T, Hashiguchi T, Hamada T, Shiba N, Ohshima K.

PLoS One. 2017 Nov 14;12(11):e0188096. doi: 10.1371/journal.pone.0188096. eCollection 2017.


Indirubin derivatives protect against endoplasmic reticulum stress-induced cytotoxicity and down-regulate CHOP levels in HT22 cells.

Kosuge Y, Saito H, Haraguchi T, Ichimaru Y, Ohashi S, Miyagishi H, Kobayashi S, Ishige K, Miyairi S, Ito Y.

Bioorg Med Chem Lett. 2017 Dec 1;27(23):5122-5125. doi: 10.1016/j.bmcl.2017.10.069. Epub 2017 Oct 28.


Frontotemporal lobar degeneration due to P301L tau mutation showing apathy and severe frontal atrophy but lacking other behavioral changes: A case report and literature review.

Miki T, Yokota O, Takenoshita S, Mori Y, Yamazaki K, Ozaki Y, Ueno SI, Haraguchi T, Ishizu H, Kuroda S, Terada S, Yamada N.

Neuropathology. 2018 Jun;38(3):268-280. doi: 10.1111/neup.12441. Epub 2017 Nov 6.


Aldehyde dehydrogenase activity helps identify a subpopulation of murine adipose-derived stem cells with enhanced adipogenic and osteogenic differentiation potential.

Itoh H, Nishikawa S, Haraguchi T, Arikawa Y, Eto S, Hiyama M, Iseri T, Itoh Y, Nakaichi M, Sakai Y, Tani K, Taura Y, Itamoto K.

World J Stem Cells. 2017 Oct 26;9(10):179-186. doi: 10.4252/wjsc.v9.i10.179.


Oncolytic reovirus therapy: Pilot study in dogs with spontaneously occurring tumours.

Hwang CC, Igase M, Sakurai M, Haraguchi T, Tani K, Itamoto K, Shimokawa T, Nakaichi M, Nemoto Y, Noguchi S, Coffey M, Okuda M, Mizuno T.

Vet Comp Oncol. 2018 Jun;16(2):229-238. doi: 10.1111/vco.12361. Epub 2017 Oct 27.


Establishment of a dog primary prostate cancer organoid using the urine cancer stem cells.

Usui T, Sakurai M, Nishikawa S, Umata K, Nemoto Y, Haraguchi T, Itamoto K, Mizuno T, Noguchi S, Mori T, Iwai S, Nakagawa T, Yamawaki H, Ohama T, Sato K.

Cancer Sci. 2017 Dec;108(12):2383-2392. doi: 10.1111/cas.13418. Epub 2017 Nov 6.


Tumor suppression via inhibition of SWI/SNF complex-dependent NF-κB activation.

Kobayashi K, Hiramatsu H, Nakamura S, Kobayashi K, Haraguchi T, Iba H.

Sci Rep. 2017 Sep 18;7(1):11772. doi: 10.1038/s41598-017-11806-9.


Neuropathological comorbidity associated with argyrophilic grain disease.

Yokota O, Miki T, Ikeda C, Nagao S, Takenoshita S, Ishizu H, Haraguchi T, Kuroda S, Terada S, Yamada N.

Neuropathology. 2018 Feb;38(1):82-97. doi: 10.1111/neup.12429. Epub 2017 Sep 14. Review.


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