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Items: 1 to 50 of 88

1.

Rare variants in RNF213, a susceptibility gene for moyamoya disease, are found in patients with pulmonary hypertension and aggravate hypoxia-induced pulmonary hypertension in mice.

Kobayashi H, Kabata R, Kinoshita H, Morimoto T, Ono K, Takeda M, Choi J, Okuda H, Liu W, Harada KH, Kimura T, Youssefian S, Koizumi A.

Pulm Circ. 2018 Jul-Sep;8(3):2045894018778155. doi: 10.1177/2045894018778155. Epub 2018 May 2.

2.

Contamination trends and factors affecting the transfer of hexabromocyclododecane diastereomers, tetrabromobisphenol A, and 2,4,6-tribromophenol to breast milk in Japan.

Fujii Y, Kato Y, Masuda N, Harada KH, Koizumi A, Haraguchi K.

Environ Pollut. 2018 Jun;237:936-943. doi: 10.1016/j.envpol.2018.03.015. Epub 2018 Mar 20.

PMID:
29572047
3.

Dysregulation of RNF213 promotes cerebral hypoperfusion.

Morimoto T, Enmi JI, Hattori Y, Iguchi S, Saito S, Harada KH, Okuda H, Mineharu Y, Takagi Y, Youssefian S, Iida H, Miyamoto S, Ihara M, Kobayashi H, Koizumi A.

Sci Rep. 2018 Feb 26;8(1):3607. doi: 10.1038/s41598-018-22064-8.

4.

β-cell-specific overexpression of adiponectin receptor 1 does not improve diabetes mellitus in Akita mice.

Choi J, Kobayashi H, Okuda H, Harada KH, Takeda M, Fujimoto H, Yamane S, Tanaka D, Youssefian S, Inagaki N, Koizumi A.

PLoS One. 2018 Jan 5;13(1):e0190863. doi: 10.1371/journal.pone.0190863. eCollection 2018.

5.

RNF213 p.R4810K Variant and Intracranial Arterial Stenosis or Occlusion in Relatives of Patients with Moyamoya Disease.

Matsuda Y, Mineharu Y, Kimura M, Takagi Y, Kobayashi H, Hitomi T, Harada KH, Uchihashi Y, Funaki T, Miyamoto S, Koizumi A.

J Stroke Cerebrovasc Dis. 2017 Aug;26(8):1841-1847. doi: 10.1016/j.jstrokecerebrovasdis.2017.04.019. Epub 2017 May 11.

PMID:
28506590
6.

Major determinants for the selecting antithrombotic therapies in patients with nonvalvular atrial fibrillation in Japan (JAPAF study).

Kusakawa K, Harada KH, Kagimura T, Koizumi A.

J Arrhythm. 2017 Apr;33(2):99-106. doi: 10.1016/j.joa.2016.06.006. Epub 2016 Aug 11.

7.

Significant association of RNF213 p.R4810K, a moyamoya susceptibility variant, with coronary artery disease.

Morimoto T, Mineharu Y, Ono K, Nakatochi M, Ichihara S, Kabata R, Takagi Y, Cao Y, Zhao L, Kobayashi H, Harada KH, Takenaka K, Funaki T, Yokota M, Matsubara T, Yamamoto K, Izawa H, Kimura T, Miyamoto S, Koizumi A.

PLoS One. 2017 Apr 17;12(4):e0175649. doi: 10.1371/journal.pone.0175649. eCollection 2017.

8.

Long-term trends in dietary intake of perfluoroalkyl carboxylic acids in relation to their serum concentration in two regions in Japan from 1979 to 2011.

Fujii Y, Harada KH, Haraguchi K, Koizumi A.

Chemosphere. 2017 Jun;176:165-174. doi: 10.1016/j.chemosphere.2017.02.073. Epub 2017 Feb 17.

PMID:
28260656
9.

Lactational exposure to short-chain chlorinated paraffins in China, Korea, and Japan.

Cao Y, Harada KH, Hitomi T, Niisoe T, Wang P, Shi Y, Yang HR, Takasuga T, Koizumi A.

Chemosphere. 2017 Apr;173:43-48. doi: 10.1016/j.chemosphere.2016.12.078. Epub 2017 Jan 6.

PMID:
28107714
10.

RNF213 Rare Variants in Slovakian and Czech Moyamoya Disease Patients.

Kobayashi H, Brozman M, Kyselová K, Viszlayová D, Morimoto T, Roubec M, Školoudík D, Petrovičová A, Juskanič D, Strauss J, Halaj M, Kurray P, Hranai M, Harada KH, Inoue S, Yoshida Y, Habu T, Herzig R, Youssefian S, Koizumi A.

PLoS One. 2016 Oct 13;11(10):e0164759. doi: 10.1371/journal.pone.0164759. eCollection 2016.

11.

Spatial and temporal trends in perfluorooctanoic and perfluorohexanoic acid in well, surface, and tap water around a fluoropolymer plant in Osaka, Japan.

Shiwaku Y, Lee P, Thepaksorn P, Zheng B, Koizumi A, Harada KH.

Chemosphere. 2016 Dec;164:603-610. doi: 10.1016/j.chemosphere.2016.09.006. Epub 2016 Sep 13.

PMID:
27635642
12.

Levels, profiles and dietary sources of hydroxylated PCBs and hydroxylated and methoxylated PBDEs in Japanese women serum samples.

Haraguchi K, Ito Y, Takagi M, Fujii Y, Harada KH, Koizumi A.

Environ Int. 2016 Dec;97:155-162. doi: 10.1016/j.envint.2016.08.022. Epub 2016 Sep 9.

PMID:
27615405
13.

Significant Association of the RNF213 p.R4810K Polymorphism with Quasi-Moyamoya Disease.

Morimoto T, Mineharu Y, Kobayashi H, Harada KH, Funaki T, Takagi Y, Sakai N, Miyamoto S, Koizumi A.

J Stroke Cerebrovasc Dis. 2016 Nov;25(11):2632-2636. doi: 10.1016/j.jstrokecerebrovasdis.2016.07.004. Epub 2016 Jul 28.

PMID:
27476341
14.
15.

Frequency of RNF213 p.R4810K, a susceptibility variant for moyamoya disease, and health characteristics of carriers in the Japanese population.

Cao Y, Kobayashi H, Morimoto T, Kabata R, Harada KH, Koizumi A.

Environ Health Prev Med. 2016 Sep;21(5):387-390. doi: 10.1007/s12199-016-0549-8. Epub 2016 Jun 30.

16.

Infantile Pain Episodes Associated with Novel Nav1.9 Mutations in Familial Episodic Pain Syndrome in Japanese Families.

Okuda H, Noguchi A, Kobayashi H, Kondo D, Harada KH, Youssefian S, Shioi H, Kabata R, Domon Y, Kubota K, Kitano Y, Takayama Y, Hitomi T, Ohno K, Saito Y, Asano T, Tominaga M, Takahashi T, Koizumi A.

PLoS One. 2016 May 25;11(5):e0154827. doi: 10.1371/journal.pone.0154827. eCollection 2016.

17.

Biological Monitoring of Human Exposure to Neonicotinoids Using Urine Samples, and Neonicotinoid Excretion Kinetics.

Harada KH, Tanaka K, Sakamoto H, Imanaka M, Niisoe T, Hitomi T, Kobayashi H, Okuda H, Inoue S, Kusakawa K, Oshima M, Watanabe K, Yasojima M, Takasuga T, Koizumi A.

PLoS One. 2016 Jan 5;11(1):e0146335. doi: 10.1371/journal.pone.0146335. eCollection 2016.

18.

A new horizon of moyamoya disease and associated health risks explored through RNF213.

Koizumi A, Kobayashi H, Hitomi T, Harada KH, Habu T, Youssefian S.

Environ Health Prev Med. 2016 Mar;21(2):55-70. doi: 10.1007/s12199-015-0498-7. Epub 2015 Dec 10. Review.

19.

Temporal Levels of Urinary Neonicotinoid and Dialkylphosphate Concentrations in Japanese Women Between 1994 and 2011.

Ueyama J, Harada KH, Koizumi A, Sugiura Y, Kondo T, Saito I, Kamijima M.

Environ Sci Technol. 2015 Dec 15;49(24):14522-8. doi: 10.1021/acs.est.5b03062. Epub 2015 Nov 25.

PMID:
26556224
20.

Neonicotinoid concentrations in urine from chronic kidney disease patients in the North Central Region of Sri Lanka.

Kabata R, Nanayakkara S, Senevirathna S, Harada KH, Chandrajith R, Hitomi T, Abeysekera T, Takasuga T, Koizumi A.

J Occup Health. 2016;58(1):128-33. doi: 10.1539/joh.15-0140-BR. Epub 2015 Nov 7.

21.

Post-Accident Sporadic Releases of Airborne Radionuclides from the Fukushima Daiichi Nuclear Power Plant Site.

Steinhauser G, Niisoe T, Harada KH, Shozugawa K, Schneider S, Synal HA, Walther C, Christl M, Nanba K, Ishikawa H, Koizumi A.

Environ Sci Technol. 2015 Dec 15;49(24):14028-35. doi: 10.1021/acs.est.5b03155. Epub 2015 Nov 25.

PMID:
26448161
22.

Biochemical and Functional Characterization of RNF213 (Mysterin) R4810K, a Susceptibility Mutation of Moyamoya Disease, in Angiogenesis In Vitro and In Vivo.

Kobayashi H, Matsuda Y, Hitomi T, Okuda H, Shioi H, Matsuda T, Imai H, Sone M, Taura D, Harada KH, Habu T, Takagi Y, Miyamoto S, Koizumi A.

J Am Heart Assoc. 2015 Jun 30;4(7). pii: e002146. doi: 10.1161/JAHA.115.002146.

23.

Whole-exome sequencing reveals genetic variants associated with chronic kidney disease characterized by tubulointerstitial damages in North Central Region, Sri Lanka.

Nanayakkara S, Senevirathna ST, Parahitiyawa NB, Abeysekera T, Chandrajith R, Ratnatunga N, Hitomi T, Kobayashi H, Harada KH, Koizumi A.

Environ Health Prev Med. 2015 Sep;20(5):354-9. doi: 10.1007/s12199-015-0475-1. Epub 2015 Jun 25.

24.

Short-chain chlorinated paraffins in cooking oil and related products from China.

Cao Y, Harada KH, Liu W, Yan J, Zhao C, Niisoe T, Adachi A, Fujii Y, Nouda C, Takasuga T, Koizumi A.

Chemosphere. 2015 Nov;138:104-11. doi: 10.1016/j.chemosphere.2015.05.063. Epub 2015 Jun 4.

PMID:
26051978
25.

Perfluorinated carboxylic acids discharged from the Yodo River Basin, Japan.

Niisoe T, Senevirathna ST, Harada KH, Fujii Y, Hitomi T, Kobayashi H, Yan J, Zhao C, Oshima M, Koizumi A.

Chemosphere. 2015 Nov;138:81-8. doi: 10.1016/j.chemosphere.2015.05.060. Epub 2015 Jun 1.

PMID:
26037820
26.

Importance of molecular diagnosis in the accurate diagnosis of systemic carnitine deficiency.

Hitomi T, Matsuura N, Shigematsu Y, Okano Y, Shinozaki E, Kawai M, Kobayashi H, Harada KH, Koizumi A.

J Genet. 2015 Mar;94(1):147-50. No abstract available.

27.

Genetic study of intracranial aneurysms.

Yan J, Hitomi T, Takenaka K, Kato M, Kobayashi H, Okuda H, Harada KH, Koizumi A.

Stroke. 2015 Mar;46(3):620-6. doi: 10.1161/STROKEAHA.114.007286. Epub 2015 Feb 3.

PMID:
25649796
28.

Long-chain perfluoroalkyl carboxylic acids in Pacific cods from coastal areas in northern Japan: a major source of human dietary exposure.

Fujii Y, Sakurada T, Harada KH, Koizumi A, Kimura O, Endo T, Haraguchi K.

Environ Pollut. 2015 Apr;199:35-41. doi: 10.1016/j.envpol.2015.01.007. Epub 2015 Jan 22.

PMID:
25618364
29.

Toxicokinetics of perfluoroalkyl carboxylic acids with different carbon chain lengths in mice and humans.

Fujii Y, Niisoe T, Harada KH, Uemoto S, Ogura Y, Takenaka K, Koizumi A.

J Occup Health. 2015;57(1):1-12. doi: 10.1539/joh.14-0136-OA. Epub 2014 Nov 21.

30.

Pentafluorobenzyl esterification of haloacetic acids in tap water for simple and sensitive analysis by gas chromatography/mass spectrometry with negative chemical ionization.

Zhao C, Fujii Y, Yan J, Harada KH, Koizumi A.

Chemosphere. 2015 Jan;119:711-718. doi: 10.1016/j.chemosphere.2014.07.048. Epub 2014 Sep 1.

PMID:
25180822
31.

Methylmercury monitoring study in Karakuwacho peninsula area in Japan.

Yan J, Inoue K, Asakawa A, Harada KH, Watanabe T, Hachiya N, Koizumi A.

Bull Environ Contam Toxicol. 2014 Jul;93(1):36-41. doi: 10.1007/s00128-014-1241-6. Epub 2014 Mar 6.

PMID:
24599146
32.

Radiation dose rates now and in the future for residents neighboring restricted areas of the Fukushima Daiichi Nuclear Power Plant.

Harada KH, Niisoe T, Imanaka M, Takahashi T, Amako K, Fujii Y, Kanameishi M, Ohse K, Nakai Y, Nishikawa T, Saito Y, Sakamoto H, Ueyama K, Hisaki K, Ohara E, Inoue T, Yamamoto K, Matsuoka Y, Ohata H, Toshima K, Okada A, Sato H, Kuwamori T, Tani H, Suzuki R, Kashikura M, Nezu M, Miyachi Y, Arai F, Kuwamori M, Harada S, Ohmori A, Ishikawa H, Koizumi A.

Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):E914-23. doi: 10.1073/pnas.1315684111. Epub 2014 Feb 24.

33.

An integrative study of the genetic, social and environmental determinants of chronic kidney disease characterized by tubulointerstitial damages in the North Central Region of Sri Lanka.

Nanayakkara S, Senevirathna ST, Abeysekera T, Chandrajith R, Ratnatunga N, Gunarathne ED, Yan J, Hitomi T, Muso E, Komiya T, Harada KH, Liu W, Kobayashi H, Okuda H, Sawatari H, Matsuda F, Yamada R, Watanabe T, Miyataka H, Himeno S, Koizumi A.

J Occup Health. 2014;56(1):28-38. Epub 2013 Dec 18.

34.

Temporal trend and age-dependent serum concentration of phenolic organohalogen contaminants in Japanese men during 1989-2010.

Fujii Y, Harada KH, Hitomi T, Kobayashi H, Koizumi A, Haraguchi K.

Environ Pollut. 2014 Feb;185:228-33. doi: 10.1016/j.envpol.2013.11.002. Epub 2013 Nov 27.

PMID:
24291611
35.

Dietary exposure to phenolic and methoxylated organohalogen contaminants in relation to their concentrations in breast milk and serum in Japan.

Fujii Y, Nishimura E, Kato Y, Harada KH, Koizumi A, Haraguchi K.

Environ Int. 2014 Feb;63:19-25. doi: 10.1016/j.envint.2013.10.016. Epub 2013 Nov 19.

PMID:
24263137
36.

The moyamoya disease susceptibility variant RNF213 R4810K (rs112735431) induces genomic instability by mitotic abnormality.

Hitomi T, Habu T, Kobayashi H, Okuda H, Harada KH, Osafune K, Taura D, Sone M, Asaka I, Ameku T, Watanabe A, Kasahara T, Sudo T, Shiota F, Hashikata H, Takagi Y, Morito D, Miyamoto S, Nakao K, Koizumi A.

Biochem Biophys Res Commun. 2013 Oct 4;439(4):419-26. doi: 10.1016/j.bbrc.2013.08.067. Epub 2013 Aug 27.

PMID:
23994138
37.

Occurrence of perfluorinated carboxylic acids (PFCAs) in personal care products and compounding agents.

Fujii Y, Harada KH, Koizumi A.

Chemosphere. 2013 Sep;93(3):538-44. doi: 10.1016/j.chemosphere.2013.06.049. Epub 2013 Aug 6.

PMID:
23932147
38.

(137)Cs trapped by biomass within 20 km of the Fukushima Daiichi Nuclear Power Plant.

Koizumi A, Niisoe T, Harada KH, Fujii Y, Adachi A, Hitomi T, Ishikawa H.

Environ Sci Technol. 2013 Sep 3;47(17):9612-8. doi: 10.1021/es401422g. Epub 2013 Aug 23.

PMID:
23889208
39.

Downregulation of Securin by the variant RNF213 R4810K (rs112735431, G>A) reduces angiogenic activity of induced pluripotent stem cell-derived vascular endothelial cells from moyamoya patients.

Hitomi T, Habu T, Kobayashi H, Okuda H, Harada KH, Osafune K, Taura D, Sone M, Asaka I, Ameku T, Watanabe A, Kasahara T, Sudo T, Shiota F, Hashikata H, Takagi Y, Morito D, Miyamoto S, Nakao K, Koizumi A.

Biochem Biophys Res Commun. 2013 Aug 16;438(1):13-9. doi: 10.1016/j.bbrc.2013.07.004. Epub 2013 Jul 12.

PMID:
23850618
40.

Protein S K196E mutation, a genetic risk factor for venous thromboembolism, is limited to Japanese.

Liu W, Yin T, Okuda H, Harada KH, Li Y, Xu B, Yang J, Wang H, Fan X, Koizumi A, Miyata T.

Thromb Res. 2013 Aug;132(2):314-5. doi: 10.1016/j.thromres.2013.05.008. Epub 2013 May 27. No abstract available.

PMID:
23721692
41.

Levels of urinary isoflavones and lignan polyphenols in Japanese women.

Liu W, Tanabe M, Harada KH, Koizumi A.

Environ Health Prev Med. 2013 Sep;18(5):394-400. doi: 10.1007/s12199-013-0338-6. Epub 2013 Apr 30.

42.

Combined linkage analysis and exome sequencing identifies novel genes for familial goiter.

Yan J, Takahashi T, Ohura T, Adachi H, Takahashi I, Ogawa E, Okuda H, Kobayashi H, Hitomi T, Liu W, Harada KH, Koizumi A.

J Hum Genet. 2013 Jun;58(6):366-77. doi: 10.1038/jhg.2013.20. Epub 2013 Mar 28.

PMID:
23535966
43.

Expression of E-cadherin and vascular endothelial growth factor in noncancerous liver is associated with recurrence of hepatocellular carcinoma after curative resection.

Minata M, Kudo M, Harada KH, Ikai I, Nishida N.

Oncology. 2013;84 Suppl 1:88-92. doi: 10.1159/000345896. Epub 2013 Feb 20.

PMID:
23428865
44.

The prognostic value of vascular endothelial growth factor in hepatocellular carcinoma for predicting metastasis after curative resection.

Minata M, Harada KH, Kudo M, Ikai I, Nishida N.

Oncology. 2013;84 Suppl 1:75-81. doi: 10.1159/000345894. Epub 2013 Feb 20.

PMID:
23428863
45.

Ablation of Rnf213 retards progression of diabetes in the Akita mouse.

Kobayashi H, Yamazaki S, Takashima S, Liu W, Okuda H, Yan J, Fujii Y, Hitomi T, Harada KH, Habu T, Koizumi A.

Biochem Biophys Res Commun. 2013 Mar 15;432(3):519-25. doi: 10.1016/j.bbrc.2013.02.015. Epub 2013 Feb 11.

PMID:
23410753
46.

Dietary intake of radiocesium in adult residents in Fukushima prefecture and neighboring regions after the Fukushima nuclear power plant accident: 24-h food-duplicate survey in December 2011.

Harada KH, Fujii Y, Adachi A, Tsukidate A, Asai F, Koizumi A.

Environ Sci Technol. 2013 Mar 19;47(6):2520-6. doi: 10.1021/es304128t. Epub 2013 Feb 27.

PMID:
23259847
47.

Polyfluorinated telomers in indoor air of Japanese houses.

Liu W, Takahashi S, Sakuramachi Y, Harada KH, Koizumi A.

Chemosphere. 2013 Feb;90(5):1672-7. doi: 10.1016/j.chemosphere.2012.09.062. Epub 2012 Oct 22.

PMID:
23089390
48.

Analysis of perfluoroalkyl carboxylic acids in composite dietary samples by gas chromatography/mass spectrometry with electron capture negative ionization.

Fujii Y, Harada KH, Koizumi A.

Environ Sci Technol. 2012 Oct 16;46(20):11235-42. doi: 10.1021/es302536g. Epub 2012 Oct 3.

PMID:
23030847
49.

P.R4810K, a polymorphism of RNF213, the susceptibility gene for moyamoya disease, is associated with blood pressure.

Koizumi A, Kobayashi H, Liu W, Fujii Y, Senevirathna ST, Nanayakkara S, Okuda H, Hitomi T, Harada KH, Takenaka K, Watanabe T, Shimbo S.

Environ Health Prev Med. 2013 Mar;18(2):121-9. doi: 10.1007/s12199-012-0299-1. Epub 2012 Aug 10.

50.

Comparative survey of levels of chlorinated cyclodiene pesticides in breast milk from some cities of China, Korea and Japan.

Fujii Y, Ito Y, Harada KH, Hitomi T, Koizumi A, Haraguchi K.

Chemosphere. 2012 Oct;89(4):452-7. doi: 10.1016/j.chemosphere.2012.05.098. Epub 2012 Jun 27.

PMID:
22743181

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