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Role of acyl-CoA synthetase ACSL4 in arachidonic acid metabolism.

Kuwata H, Hara S.

Prostaglandins Other Lipid Mediat. 2019 Jul 12:106363. doi: 10.1016/j.prostaglandins.2019.106363. [Epub ahead of print] Review.


[A Case of Left Upper Lobe Lung Cancer Successfully Diagnosed by Transesophageal Endoscopic Ultrasound with Bronchoscope-Guided Fine Needle Aspiration Alone].

Nemoto K, Uchimura K, Hara S, Chiba Y, Isoshima Y, Ohira H, Higashi Y, Tahara M, Uyama K, Tachiwada T, Noguchi S, Yamasaki K, Kawanami T, Yatera K.

J UOEH. 2019;41(2):243-248. doi: 10.7888/juoeh.41.243. Japanese.

Free Article

[Evaluation of the Influence of the Experience and Training of EBUS-TBNA on Diagnostic Rate and Safety].

Nakamura M, Uchimura K, Hara S, Ohira H, Chiba Y, Nemoto K, Higashi Y, Tahara M, Ikegami H, Hirano Y, Sakagami K, Uyama K, Sennari K, Tachiwada T, Kawabata H, Noguchi S, Yamasaki K, Kawanami T, Yatera K.

J UOEH. 2019;41(2):179-184. doi: 10.7888/juoeh.41.179. Japanese.

Free Article

Factors determining the reaction temperature of the solvent-free enzymatic synthesis of trehalose esters.

Ogawa S, Endo A, Kitahara N, Yamagishi T, Aoyagi S, Hara S.

Carbohydr Res. 2019 Jul 2;482:107739. doi: 10.1016/j.carres.2019.06.018. [Epub ahead of print]


Evidence for the induction of Th2 inflammation by group 2 innate lymphoid cells in response to prostaglandin D2 and cysteinyl leukotrienes in allergic rhinitis.

Tojima I, Matsumoto K, Kikuoka H, Hara S, Yamamoto S, Shimizu S, Kouzaki H, Shimizu T.

Allergy. 2019 Jul 2. doi: 10.1111/all.13974. [Epub ahead of print]


Deep learning to differentiate parkinsonian disorders separately using single midsagittal MR imaging: a proof of concept study.

Kiryu S, Yasaka K, Akai H, Nakata Y, Sugomori Y, Hara S, Seo M, Abe O, Ohtomo K.

Eur Radiol. 2019 Jul 1. doi: 10.1007/s00330-019-06327-0. [Epub ahead of print]


Pulmonary Langerhans cell histiocytosis with thyroid involvement manifesting as recurrent bilateral pneumothorax and tension bullae in a 3-year-old child.

Yokoyama S, Nakaoka T, Fukao D, Yokoyama K, Hara S, Hamahata K, Yoshida A.

Int J Surg Case Rep. 2019 Jun 20;60:239-243. doi: 10.1016/j.ijscr.2019.06.027. [Epub ahead of print]


Distal tuberosity osteotomy in open-wedge high tibial osteotomy does not exacerbate patellofemoral osteoarthritis on arthroscopic evaluation.

Horikawa T, Kubota K, Hara S, Akasaki Y.

Knee Surg Sports Traumatol Arthrosc. 2019 Jun 28. doi: 10.1007/s00167-019-05596-y. [Epub ahead of print]


Experimental study of fast-neutron production and moderation for accelerator-based BNCT system.

Koay HW, Shima T, Fukuda M, Kanda H, Hara S, Yorita T.

Appl Radiat Isot. 2019 Jun 11;152:11-17. doi: 10.1016/j.apradiso.2019.06.002. [Epub ahead of print]


Intravoxel incoherent motion perfusion in patients with Moyamoya disease: comparison with 15O-gas positron emission tomography.

Hara S, Hori M, Ueda R, Hagiwara A, Hayashi S, Inaji M, Tanaka Y, Maehara T, Ishii K, Aoki S, Nariai T.

Acta Radiol Open. 2019 May 23;8(5):2058460119846587. doi: 10.1177/2058460119846587. eCollection 2019 May.


A Patient with KL-6 Elevation with Anti-TNFα Who Could Receive Long-Term Use without Interstitial Pneumonia after Class Switch of Anti-TNFα.

Masuda T, Yoshida A, Ueno F, Hara S, Nabeta H, Umezawa S, Shirai M, Morikawa Y, Morizane T, Endo Y, Hibi T.

Inflamm Intest Dis. 2019 May;4(1):35-40. doi: 10.1159/000497778. Epub 2019 Mar 25.


Thioredoxin-like2/2-Cys peroxiredoxin redox cascade acts as oxidative activator of glucose-6-phosphate dehydrogenase in chloroplasts.

Yoshida K, Uchikoshi E, Hara S, Hisabori T.

Biochem J. 2019 Jun 26;476(12):1781-1790. doi: 10.1042/BCJ20190336.


[A Case of Castleman's Disease with Lymphadenopathy during the Treatment of Gastric Cancer].

Shimura Y, Hirao T, Hara S, Takayama K, Teranishi R, Ohashi T, Osawa H, Sakai K, Yasumasa K, Noro H, Iwasaki T, Nishioka Y, Hatanaka N, Yamasaki Y.

Gan To Kagaku Ryoho. 2019 Apr;46(4):739-741. Japanese.


The Speed of Sound in Rat Liver With Steatohepatitis: Ex Vivo Analysis Using Two Types of Ultrasound Systems.

Kumagai H, Taniguchi N, Yokoyama K, Katsuyama K, Yamamoto H, Hara S, Hirota N, Itoh K, Yamagata T.

Ultrasound Med Biol. 2019 Aug;45(8):2258-2265. doi: 10.1016/j.ultrasmedbio.2019.05.004. Epub 2019 May 29.


Possible role of complement factor H in podocytes in clearing glomerular subendothelial immune complex deposits.

Zoshima T, Hara S, Yamagishi M, Pastan I, Matsusaka T, Kawano M, Nagata M.

Sci Rep. 2019 May 27;9(1):7857. doi: 10.1038/s41598-019-44380-3.


Heat shock factor 1 protects germ cell proliferation during early ovarian differentiation in medaka.

Furukawa F, Hamasaki S, Hara S, Uchimura T, Shiraishi E, Osafune N, Takagi H, Yazawa T, Kamei Y, Kitano T.

Sci Rep. 2019 May 6;9(1):6927. doi: 10.1038/s41598-019-43472-4.


Analysis on the Substrate Specificity of Recombinant Human Acyl-CoA Synthetase ACSL4 Variants.

Shimbara-Matsubayashi S, Kuwata H, Tanaka N, Kato M, Hara S.

Biol Pharm Bull. 2019;42(5):850-855. doi: 10.1248/bpb.b19-00085.


Identification and application of p75 neurotrophin receptor-expressing human trabecular meshwork progenitor cells.

Hara S, Tsujikawa M, Nishida K.

Biochem Biophys Res Commun. 2019 Jun 30;514(3):580-585. doi: 10.1016/j.bbrc.2019.04.178. Epub 2019 May 4.


A Long-term Survival after Surgical Treatment for Atypical Aortic Coarctation Complicating Takayasu Arteritis with Inactive Disease at the Diagnosis: An Appropriately Treated Autopsy Case.

Yoshida M, Zoshima T, Hara S, Mizushima I, Fujii H, Yamada K, Sato Y, Harada K, Kawano M.

Intern Med. 2019 Apr 17. doi: 10.2169/internalmedicine.2483-18. [Epub ahead of print]


Preparation of Crystallites for Oriented Poly(Lactic Acid) Films Using a Casting Method under a Magnetic Field.

Hara S, Watanabe S, Takahashi K, Shimizu S, Ikake H.

Polymers (Basel). 2018 Sep 29;10(10). pii: E1083. doi: 10.3390/polym10101083.


Successful Triple Combination Immunosuppressive Therapy with Prednisolone, Cyclosporine, and Mycophenolate Mofetil to Treat Recurrent Giant Cell Myocarditis.

Akita T, Mori S, Onishi A, Hara S, Yamada H, Nagasawa A, Imada H, Shimoura H, Ooka J, Tanaka H, Hirata KI.

Intern Med. 2019 Mar 28. doi: 10.2169/internalmedicine.2471-18. [Epub ahead of print]


Identification of Nitrogen-Fixing Bradyrhizobium Associated With Roots of Field-Grown Sorghum by Metagenome and Proteome Analyses.

Hara S, Morikawa T, Wasai S, Kasahara Y, Koshiba T, Yamazaki K, Fujiwara T, Tokunaga T, Minamisawa K.

Front Microbiol. 2019 Mar 12;10:407. doi: 10.3389/fmicb.2019.00407. eCollection 2019.


[Two Cases of Pancreatectomy for Pancreatic Metastasis from Renal Cell Carcinoma].

Teranishi R, Hatanaka N, Hara S, Takayama K, Shimura Y, Ohashi T, Osawa H, Sakai K, Yasumasa K, Noro H, Hirao T, Iwasaki T, Yamasaki Y, Fujimoto N.

Gan To Kagaku Ryoho. 2019 Mar;46(3):561-563. Japanese.


[A Case of Long-Term Survival after Repeated Multidisciplinary Treatment for Liver Metastasis of Ampullary Cancer].

Ohashi T, Sakai K, Hara S, Takayama K, Shimura Y, Teranishi R, Osawa H, Yasumasa K, Noro H, Hirao T, Iwasaki T, Hatanaka N, Yamasaki Y.

Gan To Kagaku Ryoho. 2019 Feb;46(2):306-308. Japanese.


Clinicopathological characteristics of thrombospondin type 1 domain-containing 7A-associated membranous nephropathy.

Hara S, Tsuji T, Fukasawa Y, Hisano S, Morito S, Hyodo T, Goto S, Nishi S, Yoshimoto A, Itoh T.

Virchows Arch. 2019 Jun;474(6):735-743. doi: 10.1007/s00428-019-02558-0. Epub 2019 Mar 14.


Ectopic expression of DNA methyltransferases DNMT3A2 and DNMT3L leads to aberrant hypermethylation and postnatal lethality in mice.

Sasaki K, Hara S, Yamakami R, Sato Y, Hasegawa S, Kono T, Morohaku K, Obata Y.

Mol Reprod Dev. 2019 Jun;86(6):614-623. doi: 10.1002/mrd.23137. Epub 2019 Mar 4.


Viral load and inflammatory cytokine dynamics associated with the prognosis of severe fever with thrombocytopenia syndrome virus infection: An autopsy case.

Nakamura S, Iwanaga N, Hara S, Shimada S, Kashima Y, Hayasaka D, Abe K, Izumikawa K, Yanagihara K, Miyazaki Y, Morita K, Kohno S, Mukae H.

J Infect Chemother. 2019 Jun;25(6):480-484. doi: 10.1016/j.jiac.2019.01.013. Epub 2019 Feb 26.


Inhibitory effects of polysorbate 80 on MRSA biofilm formed on different substrates including dermal tissue.

Ueda Y, Mashima K, Miyazaki M, Hara S, Takata T, Kamimura H, Takagi S, Jimi S.

Sci Rep. 2019 Feb 28;9(1):3128. doi: 10.1038/s41598-019-39997-3.


Association of Thyrotropin Concentration with Chronic Kidney Disease in a Japanese General Population Cohort.

Toda A, Hara S, Kato M, Tsuji H, Arase Y.

Nephron. 2019;142(2):91-97. doi: 10.1159/000497326. Epub 2019 Feb 22.


Administration of tetrahydrobiopterin restored the decline of dopamine in the striatum induced by an acute action of MPTP.

Kurosaki H, Yamaguchi K, Man-Yoshi K, Muramatsu SI, Hara S, Ichinose H.

Neurochem Int. 2019 May;125:16-24. doi: 10.1016/j.neuint.2019.02.005. Epub 2019 Feb 7.


A case report of crystalline light chain inclusion-associated kidney disease affecting podocytes but without Fanconi syndrome: A clonal analysis of pathological monoclonal light chain.

Ito K, Hara S, Yamada K, Zoshima T, Mizushima I, Fujii H, Miyazaki R, Kawai Y, Yachie A, Nagata M, Izui S, Yamagishi M, Kawano M.

Medicine (Baltimore). 2019 Feb;98(5):e13915. doi: 10.1097/MD.0000000000013915.


A case of apolipoprotein E Toyonaka and homozygous apolipoprotein E2/2 showing non-immune membranous nephropathy-like glomerular lesions with foamy changes.

Kato T, Ushiogi Y, Yokoyama H, Hara S, Matsunaga A, Muso E, Saito T.

CEN Case Rep. 2019 May;8(2):106-111. doi: 10.1007/s13730-019-00380-w. Epub 2019 Jan 30.


[A Case of Rectosigmoid Cancer with Intestinal Malrotation Treated with Laparoscopic Surgery].

Osawa H, Yasumasa K, Hara S, Shimura Y, Teranishi R, Ohashi T, Sakai K, Noro H, Hirao T, Hatanaka N, Yamasaki Y.

Gan To Kagaku Ryoho. 2018 Dec;45(13):2015-2017. Japanese.


Unraveling Specific Brain Microstructural Damage in Moyamoya Disease Using Diffusion Magnetic Resonance Imaging and Positron Emission Tomography.

Hara S, Hori M, Ueda R, Hayashi S, Inaji M, Tanaka Y, Maehara T, Ishii K, Aoki S, Nariai T.

J Stroke Cerebrovasc Dis. 2019 Apr;28(4):1113-1125. doi: 10.1016/j.jstrokecerebrovasdis.2018.12.038. Epub 2019 Jan 21.


Fabrication of Uniaxially Aligned Silica Nanogrooves with Sub-5 nm Periodicity on Centimeter-Scale Si Substrate Using Poly(dimethylsiloxane) Stamps.

Hirota K, Hara S, Wada H, Shimojima A, Kuroda K.

ACS Nano. 2019 Mar 26;13(3):2795-2803. doi: 10.1021/acsnano.8b07714. Epub 2019 Jan 23.


Pair analysis and custom array CGH can detect a small copy number variation in COQ6 gene.

Nakanishi K, Okamoto T, Nozu K, Hara S, Sato Y, Hayashi A, Takahashi T, Nagano C, Sakakibara N, Horinouchi T, Fujimura J, Minamikawa S, Yamamura T, Rossanti R, Nagase H, Kaito H, Ariga T, Iijima K.

Clin Exp Nephrol. 2019 May;23(5):669-675. doi: 10.1007/s10157-018-1682-z. Epub 2018 Dec 24.


IgM-mediated Warm Autoimmune Hemolytic Anemia: An Autopsy Report.

Ito T, Tojo N, Takashiro K, Yoshimura K, Yamamoto K, Hara S, Takesue K, Yoshimatsu N, Obata T, Takahara N.

Intern Med. 2019 Apr 1;58(7):999-1002. doi: 10.2169/internalmedicine.1291-18. Epub 2018 Dec 18.


Transcription factor TFAP2B up-regulates human corneal endothelial cell-specific genes during corneal development and maintenance.

Hara S, Kawasaki S, Yoshihara M, Winegarner A, Busch C, Tsujikawa M, Nishida K.

J Biol Chem. 2019 Feb 15;294(7):2460-2469. doi: 10.1074/jbc.RA118.005527. Epub 2018 Dec 14.


A case of nephrotic syndrome showing contemporary presence of apolipoprotein E2 homozygote glomerulopathy and membranous nephropathy-like findings modified by apolipoprotein E Toyonaka.

Hirashima H, Komiya T, Toriu N, Hara S, Matsunaga A, Saito T, Muso E.

Clin Nephrol Case Stud. 2018 Nov 30;6:45-51. doi: 10.5414/CNCS109509. eCollection 2018.


A 39-year-old female with cerebellar tumor and visual disturbance.

Tanaka H, Yamamoto D, Mizukawa K, Kanamori A, Chihara N, Matsuoka R, Hara S, Hirose T, Sasayama T, Kohmura E.

Brain Pathol. 2018 Nov;28(6):1027-1028. doi: 10.1111/bpa.12668. No abstract available.


Thrombotic Microangiopathy with Severe Proteinuria Induced by Lenvatinib for Radioactive Iodine-Refractory Papillary Thyroid Carcinoma.

Hyogo Y, Kiyota N, Otsuki N, Goto S, Imamura Y, Chayahara N, Toyoda M, Nibu KI, Hyodo T, Hara S, Masuoka H, Kasahara T, Ito Y, Miya A, Hirokawa M, Miyauchi A, Minami H.

Case Rep Oncol. 2018 Nov 12;11(3):735-741. doi: 10.1159/000494080. eCollection 2018 Sep-Dec.


Regression of White Matter Hyperintensity after Indirect Bypass Surgery in a Patient with Moyamoya Disease.

Hara S, Hori M, Inaji M, Maehara T, Aoki S, Nariai T.

Magn Reson Med Sci. 2018 Dec 6. doi: 10.2463/ [Epub ahead of print] No abstract available.


Mapping of a responsible region for sex reversal upstream of Sox9 by production of mice with serial deletion in a genomic locus.

Ogawa Y, Terao M, Hara S, Tamano M, Okayasu H, Kato T, Takada S.

Sci Rep. 2018 Nov 30;8(1):17514. doi: 10.1038/s41598-018-35746-0.


Reversible S-glutathionylation of human 6-pyruvoyl tetrahydropterin synthase protects its enzymatic activity.

Hara S, Fukumura S, Ichinose H.

J Biol Chem. 2019 Jan 25;294(4):1420-1427. doi: 10.1074/jbc.RA118.005280. Epub 2018 Dec 4.


10 Fr S-Type Plastic Pancreatic Stents in Chronic Pancreatitis Are Effective for the Treatment of Pancreatic Duct Strictures and Pancreatic Stones.

Ito K, Okano N, Hara S, Takuma K, Yoshimoto K, Iwasaki S, Kishimoto Y, Igarashi Y.

Gastroenterol Res Pract. 2018 Oct 25;2018:6056379. doi: 10.1155/2018/6056379. eCollection 2018.


A case of membranous nephropathy characterized by atypical distribution of phospholipase A2 receptor

Hyodo T, Saito K, Kono K, Nishi S, Itoh T, Hara S.

Clin Nephrol. 2019 Feb;91(2):114-119. doi: 10.5414/CN109567.


Pseudoprogression in Previously Treated Patients with Non-Small Cell Lung Cancer Who Received Nivolumab Monotherapy.

Fujimoto D, Yoshioka H, Kataoka Y, Morimoto T, Hata T, Kim YH, Tomii K, Ishida T, Hirabayashi M, Hara S, Ishitoko M, Fukuda Y, Hwang MH, Sakai N, Fukui M, Nakaji H, Morita M, Mio T, Yasuda T, Sugita T, Hirai T.

J Thorac Oncol. 2019 Mar;14(3):468-474. doi: 10.1016/j.jtho.2018.10.167. Epub 2018 Nov 20.


Telomere shortening in alcohol dependence: Roles of alcohol and acetaldehyde.

Yamaki N, Matsushita S, Hara S, Yokoyama A, Hishimoto A, Higuchi S.

J Psychiatr Res. 2019 Feb;109:27-32. doi: 10.1016/j.jpsychires.2018.11.007. Epub 2018 Nov 8.


Discovery of naldemedine: A potent and orally available opioid receptor antagonist for treatment of opioid-induced adverse effects.

Inagaki M, Kume M, Tamura Y, Hara S, Goto Y, Haga N, Hasegawa T, Nakamura T, Koike K, Oonishi S, Kanemasa T, Kai H.

Bioorg Med Chem Lett. 2019 Jan 1;29(1):73-77. doi: 10.1016/j.bmcl.2018.11.007. Epub 2018 Nov 7.


Effect of Position and Fastening Belt Pressure on the Accuracy of PPG-Based Heart Rate Sensor.

Shimazaki T, Kuwahara Y, Kimoto M, Hara S, Yomo H.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:4323-4326. doi: 10.1109/EMBC.2018.8513333.


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