Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 2976

1.

IgG immune complexes with Staphylococcus aureus protein A enhance osteoclast differentiation and bone resorption by stimulating Fc receptors and TLR2.

Kamohara A, Hirata H, Xu X, Shiraki M, Yamada S, Zhang JQ, Kukita T, Toyonaga K, Hara H, Urano Y, Yamashita Y, Miyamoto H, Kukita A.

Int Immunol. 2019 Nov 12. pii: dxz063. doi: 10.1093/intimm/dxz063. [Epub ahead of print]

PMID:
31713625
2.

The N-Terminal Polybasic Region of Prion Protein Is Crucial in Prion Pathogenesis Independently of the Octapeptide Repeat Region.

Das NR, Miyata H, Hara H, Chida J, Uchiyama K, Masujin K, Watanabe H, Kondoh G, Sakaguchi S.

Mol Neurobiol. 2019 Nov 9. doi: 10.1007/s12035-019-01804-5. [Epub ahead of print]

PMID:
31707632
3.

A novel EWSR1-VGLL1 gene fusion in a soft tissue malignant myoepithelial tumor.

Komatsu M, Kawamoto T, Kanzawa M, Kawakami Y, Hara H, Akisue T, Kuroda R, Nakamura H, Hokka D, Jimbo N, Itoh T, Hirose T.

Genes Chromosomes Cancer. 2019 Nov 7. doi: 10.1002/gcc.22823. [Epub ahead of print]

PMID:
31697442
4.

A novel free radical scavenger, NSP-116, ameliorated the brain injury in both ischemic and hemorrhagic stroke models.

Imai T, Iwata S, Miyo D, Nakamura S, Shimazawa M, Hara H.

J Pharmacol Sci. 2019 Oct 15. pii: S1347-8613(19)35715-9. doi: 10.1016/j.jphs.2019.09.012. [Epub ahead of print]

5.

Analysis of Heart Rate Variability in a Patient with Takotsubo Cardiomyopathy Syndrome on the Actual Onset Day.

Kujime S, Hara H, Enomoto Y, Nakamura K, Yoshitama T, Noro M, Moroi M, Sugi K, Nakamura M.

Int Heart J. 2019 Oct 31. doi: 10.1536/ihj.19-092. [Epub ahead of print]

6.

Reduced Cholinergic Activity in the Hippocampus of Hippocampal Cholinergic Neurostimulating Peptide Precursor Protein Knockout Mice.

Madokoro Y, Yoshino Y, Kato D, Sato T, Mizuno M, Kanamori T, Shimazawa M, Hida H, Hara H, Yoshida M, Borlongan CV, Ojika K, Matsukawa N.

Int J Mol Sci. 2019 Oct 28;20(21). pii: E5367. doi: 10.3390/ijms20215367.

7.

Decellularization methods for developing porcine corneal xenografts and future perspectives.

Isidan A, Liu S, Li P, Lashmet M, Smith LJ, Hara H, Cooper DKC, Ekser B.

Xenotransplantation. 2019 Oct 28:e12564. doi: 10.1111/xen.12564. [Epub ahead of print] Review.

PMID:
31659811
8.

IFN‑β sensitizes TRAIL‑induced apoptosis by upregulation of death receptor 5 in malignant glioma cells.

Yoshimura S, Sano E, Hanashima Y, Yamamuro S, Sumi K, Ueda T, Nakayama T, Hara H, Yoshino A, Katayama Y.

Oncol Rep. 2019 Dec;42(6):2635-2643. doi: 10.3892/or.2019.7383. Epub 2019 Oct 22.

PMID:
31638255
9.

What Is GLP-1 Really Doing in Obesity?

Hira T, Pinyo J, Hara H.

Trends Endocrinol Metab. 2019 Oct 18. pii: S1043-2760(19)30187-0. doi: 10.1016/j.tem.2019.09.003. [Epub ahead of print] Review.

PMID:
31636017
10.

Activation and IL-10 production of specific CD4+ T cells are regulated by IL-27 during chronic infection with Plasmodium chabaudi.

Sukhbaatar O, Kimura D, Miyakoda M, Nakamae S, Kimura K, Hara H, Yoshida H, Inoue SI, Yui K.

Parasitol Int. 2020 Feb;74:101994. doi: 10.1016/j.parint.2019.101994. Epub 2019 Oct 18.

11.

Inhibition of NAMPT markedly enhances plasma-activated medium-induced cell death in human breast cancer MDA-MB-231 cells.

Nagaya M, Hara H, Kamiya T, Adachi T.

Arch Biochem Biophys. 2019 Nov 15;676:108155. doi: 10.1016/j.abb.2019.108155. Epub 2019 Oct 16.

PMID:
31628926
12.

Pertuzumab plus trastuzumab and chemotherapy for Japanese patients with HER2-positive metastatic gastric or gastroesophageal junction cancer: a subgroup analysis of the JACOB trial.

Shitara K, Hara H, Yoshikawa T, Fujitani K, Nishina T, Hosokawa A, Asakawa T, Kawakami S, Muro K.

Int J Clin Oncol. 2019 Oct 16. doi: 10.1007/s10147-019-01558-z. [Epub ahead of print]

PMID:
31620931
13.

Exclusive use of ultrasound for locating optimal LVA sites-A descriptive data analysis.

Czedik-Eysenberg M, Steinbacher J, Obermayer B, Yoshimatsu H, Hara H, Mihara M, Tzou CJ, Meng S.

J Surg Oncol. 2019 Oct 14. doi: 10.1002/jso.25728. [Epub ahead of print]

PMID:
31612513
14.

Efficacy of mepolizumab for patients with severe asthma and eosinophilic chronic rhinosinusitis.

Numata T, Nakayama K, Utsumi H, Kobayashi K, Yanagisawa H, Hashimoto M, Minagawa S, Ishikawa T, Hara H, Araya J, Kuwano K.

BMC Pulm Med. 2019 Oct 12;19(1):176. doi: 10.1186/s12890-019-0952-1.

15.

Performance of 99mTc-aprotinin scintigraphy for diagnosing light chain (AL) cardiac amyloidosis confirmed by endomyocardial biopsy.

Awaya T, Minamimoto R, Iwama K, Kubota S, Hotta M, Hirai R, Yamamoto M, Okazaki O, Hara H, Hiroi Y, Hiroe M, Moroi M.

J Nucl Cardiol. 2019 Oct 7. doi: 10.1007/s12350-019-01868-9. [Epub ahead of print]

PMID:
31591695
16.

A summary of the Clinical Practice Guideline for the Diagnosis and Management of Voice Disorders, 2018 in Japan.

Umeno H, Hyodo M, Haji T, Hara H, Imaizumi M, Ishige M, Kumada M, Makiyama K, Nishizawa N, Saito K, Shiromoto O, Suehiro A, Takahashi G, Tateya I, Tsunoda K, Omori K.

Auris Nasus Larynx. 2019 Oct 3. pii: S0385-8146(19)30528-0. doi: 10.1016/j.anl.2019.09.004. [Epub ahead of print]

PMID:
31587820
17.

ANTI-PIG ANTIBODY IN INFANTS: CAN A GENETICALLY-ENGINEERED PIG HEART BRIDGE TO ALLOTRANSPLANTATION?

Li Q, Hara H, Banks CA, Yamamoto T, Ayares D, Mauchley DC, Dabal RJ, Padilla L, Carlo WF, Rhodes LA, Cooper DKC, Cleveland DC.

Ann Thorac Surg. 2019 Sep 30. pii: S0003-4975(19)31452-3. doi: 10.1016/j.athoracsur.2019.08.061. [Epub ahead of print]

PMID:
31580857
18.

Inhibitory effects of 4-hydroperoxy-2-decenoic acid ethyl ester on phorbol ester- and TGF-β1-induced MMPs expression.

Kamiya T, Tanaka M, Hara H, Yamaguchi E, Itoh A, Adachi T.

Free Radic Res. 2019 Oct 14:1-9. doi: 10.1080/10715762.2019.1675874. [Epub ahead of print]

PMID:
31575304
19.

The Anatomical Pattern of the Proximal Jejunal Vein as a Prognostic Factor in Patients With Pancreatic Head Cancer Treated With Preoperative Chemoradiation Therapy.

Nishimura S, Takahashi H, Akita H, Asukai K, Hasegawa S, Yamada D, Wada H, Hara H, Shinno N, Ushigome H, Haraguchi N, Sugimura K, Yamamoto K, Nishimura J, Yasui M, Omori T, Miyata H, Ohue M, Yano M, Sakon M, Ishikawa O.

Anticancer Res. 2019 Oct;39(10):5821-5830. doi: 10.21873/anticanres.13786.

PMID:
31570487
20.

Combination gemcitabine plus S-1 versus gemcitabine plus cisplatin for advanced/recurrent biliary tract cancer: The FUGA-BT (JCOG1113) Randomized Phase III Clinical Trial.

Morizane C, Okusaka T, Mizusawa J, Katayama H, Ueno M, Ikeda M, Ozaka M, Okano N, Sugimori K, Fukutomi A, Hara H, Mizuno N, Yanagimoto H, Wada K, Tobimatsu K, Yane K, Nakamori S, Yamaguchi H, Asagi A, Yukisawa S, Kojima Y, Kawabe K, Kawamoto Y, Sugimoto R, Iwai T, Nakamura K, Miyakawa H, Yamashita T, Hosokawa A, Ioka T, Kato N, Shioji K, Shimizu K, Nakagohri T, Kamata K, Ishii H, Furuse J.

Ann Oncol. 2019 Sep 30. pii: mdz402. doi: 10.1093/annonc/mdz402. [Epub ahead of print]

PMID:
31566666
21.

Involvement of GPx4-Regulated Lipid Peroxidation in Idiopathic Pulmonary Fibrosis Pathogenesis.

Tsubouchi K, Araya J, Yoshida M, Sakamoto T, Koumura T, Minagawa S, Hara H, Hosaka Y, Ichikawa A, Saito N, Kadota T, Kurita Y, Kobayashi K, Ito S, Fujita Y, Utsumi H, Hashimoto M, Wakui H, Numata T, Kaneko Y, Mori S, Asano H, Matsudaira H, Ohtsuka T, Nakayama K, Nakanishi Y, Imai H, Kuwano K.

J Immunol. 2019 Oct 15;203(8):2076-2087. doi: 10.4049/jimmunol.1801232. Epub 2019 Sep 18.

PMID:
31534007
22.

Development of a denoising convolutional neural network-based algorithm for metal artifact reduction in digital tomosynthesis for arthroplasty: A phantom study.

Gomi T, Sakai R, Hara H, Watanabe Y, Mizukami S.

PLoS One. 2019 Sep 13;14(9):e0222406. doi: 10.1371/journal.pone.0222406. eCollection 2019.

23.

X-ray pumping of the 229Th nuclear clock isomer.

Masuda T, Yoshimi A, Fujieda A, Fujimoto H, Haba H, Hara H, Hiraki T, Kaino H, Kasamatsu Y, Kitao S, Konashi K, Miyamoto Y, Okai K, Okubo S, Sasao N, Seto M, Schumm T, Shigekawa Y, Suzuki K, Stellmer S, Tamasaku K, Uetake S, Watanabe M, Watanabe T, Yasuda Y, Yamaguchi A, Yoda Y, Yokokita T, Yoshimura M, Yoshimura K.

Nature. 2019 Sep;573(7773):238-242. doi: 10.1038/s41586-019-1542-3. Epub 2019 Sep 11.

PMID:
31511686
24.

β-Cryptoxanthin Induces UCP-1 Expression via a RAR Pathway in Adipose Tissue.

Hara H, Takahashi H, Mohri S, Murakami H, Kawarasaki S, Iwase M, Takahashi N, Sugiura M, Goto T, Kawada T.

J Agric Food Chem. 2019 Sep 25;67(38):10595-10603. doi: 10.1021/acs.jafc.9b01930. Epub 2019 Sep 11.

PMID:
31475817
25.

Human CTLA4-Ig therapy can give false-positive anti-pig antibody results in primates after xenotransplantation.

Li Q, Yamamoto T, Iwase H, Nguyen HQ, Wang Y, Ayares D, Cooper DKC, Hara H.

Transpl Immunol. 2019 Dec;57:101243. doi: 10.1016/j.trim.2019.101243. Epub 2019 Aug 28.

PMID:
31472231
26.

Small-Scale Panel Comprising Diverse Gene Family Targets To Evaluate Compound Promiscuity.

Sameshima T, Yukawa T, Hirozane Y, Yoshikawa M, Katoh T, Hara H, Yogo T, Miyahisa I, Okuda T, Miyamoto M, Naven R.

Chem Res Toxicol. 2019 Sep 6. doi: 10.1021/acs.chemrestox.9b00128. [Epub ahead of print]

PMID:
31461269
27.

Indicators of impending pig kidney and heart xenograft failure: Relevance to clinical organ xenotransplantation - Review article.

Iwase H, Jagdale A, Yamamoto T, Zhang G, Li Q, Foote J, Ayares D, Ekser B, Hara H, Cooper DKC.

Int J Surg. 2019 Oct;70:84-91. doi: 10.1016/j.ijsu.2019.08.024. Epub 2019 Aug 21. Review.

PMID:
31445094
28.

Temozolomide has anti-tumor effects through the phosphorylation of cPLA2 on glioblastoma cells.

Tsuji S, Ohno Y, Nakamura S, Yamada T, Noda Y, Saio M, Iwama T, Shimazawa M, Hara H.

Brain Res. 2019 Nov 15;1723:146396. doi: 10.1016/j.brainres.2019.146396. Epub 2019 Aug 20.

PMID:
31442413
29.

Downregulation of Gabarapl1 significantly attenuates antibody binding to porcine aortic endothelial cells.

Xie C, Qu Z, Hara H, Dai W, Wang X, Pan D, Zhou M, Dai Y, Cai Z, Zhang J, Cooper DKC, Mou L.

Xenotransplantation. 2019 Aug 21:e12537. doi: 10.1111/xen.12537. [Epub ahead of print]

PMID:
31433094
30.

Phase III study of tri-modality combination therapy with induction docetaxel plus cisplatin and 5-fluorouracil versus definitive chemoradiotherapy for locally advanced unresectable squamous-cell carcinoma of the thoracic esophagus (JCOG1510: TRIANgLE).

Terada M, Hara H, Daiko H, Mizusawa J, Kadota T, Hori K, Ogawa H, Ogata T, Sakanaka K, Sakamoto T, Kato K, Kitagawa Y.

Jpn J Clin Oncol. 2019 Aug 14. pii: hyz112. doi: 10.1093/jjco/hyz112. [Epub ahead of print]

PMID:
31411696
31.

The 10th Japan Bioanalysis Forum Symposium conference: a report.

Sano Y, Ohtsu Y, Igarashi H, Hosogi J, Komaba J, Mabuchi M, Yamaguchi T, Kamimori H, Arakawa T, Nakamura T, Nakai K, Hara H, Kakehi M, Suzuki S, Uchiyama H, Kawai Y, Nagao A, Nishiguchi Y.

Bioanalysis. 2019 Jul;11(14):1303-1308. doi: 10.4155/bio-2019-0174. Epub 2019 Aug 8.

32.

Sublethal treatment with plasma-activated medium induces senescence-like growth arrest of A549 cells: involvement of intracellular mobile zinc.

Hara H, Kobayashi M, Shiiba M, Kamiya T, Adachi T.

J Clin Biochem Nutr. 2019 Jul;65(1):16-22. doi: 10.3164/jcbn.19-17. Epub 2019 Jun 11.

33.

A 3-Year Overall Survival Update From a Phase 2 Study of Chemoselection With DCF and Subsequent Conversion Surgery for Locally Advanced Unresectable Esophageal Cancer.

Yokota T, Kato K, Hamamoto Y, Tsubosa Y, Ogawa H, Ito Y, Hara H, Ura T, Kojima T, Chin K, Hironaka S, Kii T, Kojima Y, Akutsu Y, Matsushita H, Kawakami K, Mori K, Makiuchi T, Nagumo R, Kitagawa Y.

Ann Surg Oncol. 2019 Aug 2. doi: 10.1245/s10434-019-07654-8. [Epub ahead of print]

PMID:
31376034
34.

Is the renal subcapsular space the preferred site for clinical porcine islet xenotransplantation? Review article.

Smood B, Bottino R, Hara H, Cooper DKC.

Int J Surg. 2019 Sep;69:100-107. doi: 10.1016/j.ijsu.2019.07.032. Epub 2019 Jul 30. Review.

PMID:
31369877
35.

Bidirectional crosstalk between neutrophils and adipocytes promotes adipose tissue inflammation.

Watanabe Y, Nagai Y, Honda H, Okamoto N, Yanagibashi T, Ogasawara M, Yamamoto S, Imamura R, Takasaki I, Hara H, Sasahara M, Arita M, Hida S, Taniguchi S, Suda T, Takatsu K.

FASEB J. 2019 Nov;33(11):11821-11835. doi: 10.1096/fj.201900477RR. Epub 2019 Jul 29.

PMID:
31355683
36.

Enhanced postprandial glucagon-like peptide-1 secretion during obesity development has a protective role against glucose intolerance induction in rats.

Pinyo J, Hira T, Hara H.

Br J Nutr. 2019 Aug 28;122(4):411-422. doi: 10.1017/S0007114519001223. Epub 2019 Jul 29.

PMID:
31352909
37.

Gemcitabine and docetaxel combination chemotherapy for advanced bone and soft tissue sarcomas: protocol for an open-label, non-randomised, Phase 2 study.

Hara H, Kawamoto T, Fukase N, Kawakami Y, Takemori T, Fujiwara S, Kitayama K, Nishida K, Kuroda R, Akisue T.

BMC Cancer. 2019 Jul 23;19(1):725. doi: 10.1186/s12885-019-5923-7.

38.

Postoperative Changes in Lymphoscintigraphic Findings After Lymphaticovenous Anastomosis.

Hara H, Mihara M.

Ann Plast Surg. 2019 Nov;83(5):548-552. doi: 10.1097/SAP.0000000000001872.

PMID:
31335464
39.

Lymphatic Vessel Thrombosis in a Patient with Secondary Lymphedema.

Hara H, Mihara M, Ohtomo R, Tanaka S.

Plast Reconstr Surg Glob Open. 2019 May 24;7(5):e2268. doi: 10.1097/GOX.0000000000002268. eCollection 2019 May.

40.

Diagnostic value of lead aVR in electrocardiography for identifying acute coronary lesions in patients with out-of-hospital cardiac arrest.

Yamamoto M, Witsch T, Kubota S, Hara H, Hiroi Y.

Resuscitation. 2019 Sep;142:97-103. doi: 10.1016/j.resuscitation.2019.07.017. Epub 2019 Jul 19.

PMID:
31330201
41.

Transmitral inflow wave and progression from paroxysmal to permanent atrial fibrillation in Asian people.

Nakagawa T, Hara H, Yamamoto M, Matsushita Y, Hiroi Y.

Heart Asia. 2019 Jun 26;11(2):e011166. doi: 10.1136/heartasia-2018-011166. eCollection 2019.

42.

Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis.

Yoshida M, Minagawa S, Araya J, Sakamoto T, Hara H, Tsubouchi K, Hosaka Y, Ichikawa A, Saito N, Kadota T, Sato N, Kurita Y, Kobayashi K, Ito S, Utsumi H, Wakui H, Numata T, Kaneko Y, Mori S, Asano H, Yamashita M, Odaka M, Morikawa T, Nakayama K, Iwamoto T, Imai H, Kuwano K.

Nat Commun. 2019 Jul 17;10(1):3145. doi: 10.1038/s41467-019-10991-7.

43.

Successful treatment of a right internal mammary artery aneurysm with thoracoscopic surgery.

Miyazaki M, Nagamine H, Hara H, Sugita H, Kawase Y.

J Vasc Surg Cases Innov Tech. 2019 Jun 25;5(3):269-272. doi: 10.1016/j.jvscit.2019.03.006. eCollection 2019 Sep.

44.

Generation and Clinical Application of Gene-Modified Autologous Epidermal Sheets in Netherton Syndrome: Lessons Learned from a Phase 1 Trial.

Di WL, Lwin SM, Petrova A, Bernadis C, Syed F, Farzaneh F, Moulding D, Martinez AE, Sebire NJ, Rampling D, Virasami A, Zamiri M, Wang W, Hara H, Kadiyirire T, Abdul-Wahab A, Martinez-Queipo M, Harper JI, McGrath JA, Thrasher AJ, Mellerio JE, Qasim W.

Hum Gene Ther. 2019 Sep;30(9):1067-1078. doi: 10.1089/hum.2019.049. Epub 2019 Aug 5.

PMID:
31288584
45.

Life-supporting Kidney Xenotransplantation From Genetically Engineered Pigs in Baboons: A Comparison of Two Immunosuppressive Regimens.

Yamamoto T, Hara H, Foote J, Wang L, Li Q, Klein EC, Schuurman HJ, Zhou H, Li J, Tector AJ, Zhang Z, Ezzelarab M, Lovingood R, Ayares D, Eckhoff DE, Cooper DKC, Iwase H.

Transplantation. 2019 Oct;103(10):2090-2104. doi: 10.1097/TP.0000000000002796.

PMID:
31283686
46.

Elucidation of prazosin biodegradation by isolated Bacillus spp. from the tropical environment.

Mohd Mohsi NF, Apandi A, Megat Mohd Noor MJ, Md Akhir FN, Sugiura N, Utsumi M, Othman N, Zakaria Z, Hara H.

J Gen Appl Microbiol. 2019 Jul 8. doi: 10.2323/jgam.2019.04.001. [Epub ahead of print]

47.

Clinical Implication of Tumor-invasive Status into the Muscularis Propria in T2 Gastric Cancer.

Nakamura K, Ogimi M, Tomioku M, Hara H, Nabeshima K, Nomura E.

In Vivo. 2019 Jul-Aug;33(4):1341-1346. doi: 10.21873/invivo.11609.

48.

ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism.

Fang R, Uchiyama R, Sakai S, Hara H, Tsutsui H, Suda T, Mitsuyama M, Kawamura I, Tsuchiya K.

Mucosal Immunol. 2019 Sep;12(5):1092-1103. doi: 10.1038/s41385-019-0181-1. Epub 2019 Jul 5.

PMID:
31278375
49.

A novel intracellular dextranase derived from Paenibacillus sp. 598K with an ability to degrade cycloisomaltooligosaccharides.

Mizushima D, Miyazaki T, Shiwa Y, Kimura K, Suzuki S, Fujita N, Yoshikawa H, Kimura A, Kitamura S, Hara H, Funane K.

Appl Microbiol Biotechnol. 2019 Aug;103(16):6581-6592. doi: 10.1007/s00253-019-09965-y. Epub 2019 Jul 4.

PMID:
31273396
50.

Reply to the Letter: Increased bioavailability of plasma polyphenols via the intestinal fermentation of soybean fibers: a role for gut microbiome?

Trakooncharoenvit A, Tanaka S, Mizuta E, Hira T, Hara H.

Eur J Nutr. 2019 Sep;58(6):2563. doi: 10.1007/s00394-019-02030-4. No abstract available.

PMID:
31263985

Supplemental Content

Support Center