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Items: 1 to 50 of 2948

1.

Downregulation of Gabarapl1 significantly attenuates antibody binding to porcine aortic endothelial cells.

Xie C, Qu Z, Hara H, Dai W, Wang X, Pan D, Zhou M, Dai Y, Cai Z, Zhang J, Cooper DKC, Mou L.

Xenotransplantation. 2019 Aug 21:e12537. doi: 10.1111/xen.12537. [Epub ahead of print]

PMID:
31433094
2.

Phase III study of tri-modality combination therapy with induction docetaxel plus cisplatin and 5-fluorouracil versus definitive chemoradiotherapy for locally advanced unresectable squamous-cell carcinoma of the thoracic esophagus (JCOG1510: TRIANgLE).

Terada M, Hara H, Daiko H, Mizusawa J, Kadota T, Hori K, Ogawa H, Ogata T, Sakanaka K, Sakamoto T, Kato K, Kitagawa Y.

Jpn J Clin Oncol. 2019 Aug 14. pii: hyz112. doi: 10.1093/jjco/hyz112. [Epub ahead of print]

PMID:
31411696
3.

The 10th Japan Bioanalysis Forum Symposium conference: a report.

Sano Y, Ohtsu Y, Igarashi H, Hosogi J, Komaba J, Mabuchi M, Yamaguchi T, Kamimori H, Arakawa T, Nakamura T, Nakai K, Hara H, Kakehi M, Suzuki S, Uchiyama H, Kawai Y, Nagao A, Nishiguchi Y.

Bioanalysis. 2019 Aug 8. doi: 10.4155/bio-2019-0174. [Epub ahead of print]

PMID:
31392898
4.

Sublethal treatment with plasma-activated medium induces senescence-like growth arrest of A549 cells: involvement of intracellular mobile zinc.

Hara H, Kobayashi M, Shiiba M, Kamiya T, Adachi T.

J Clin Biochem Nutr. 2019 Jul;65(1):16-22. doi: 10.3164/jcbn.19-17. Epub 2019 Jun 11.

5.

A 3-Year Overall Survival Update From a Phase 2 Study of Chemoselection With DCF and Subsequent Conversion Surgery for Locally Advanced Unresectable Esophageal Cancer.

Yokota T, Kato K, Hamamoto Y, Tsubosa Y, Ogawa H, Ito Y, Hara H, Ura T, Kojima T, Chin K, Hironaka S, Kii T, Kojima Y, Akutsu Y, Matsushita H, Kawakami K, Mori K, Makiuchi T, Nagumo R, Kitagawa Y.

Ann Surg Oncol. 2019 Aug 2. doi: 10.1245/s10434-019-07654-8. [Epub ahead of print]

PMID:
31376034
6.

Is the renal subcapsular space the preferred site for clinical porcine islet xenotransplantation? Review article.

Smood B, Bottino R, Hara H, Cooper DKC.

Int J Surg. 2019 Jul 30;69:100-107. doi: 10.1016/j.ijsu.2019.07.032. [Epub ahead of print] Review.

PMID:
31369877
7.

Bidirectional crosstalk between neutrophils and adipocytes promotes adipose tissue inflammation.

Watanabe Y, Nagai Y, Honda H, Okamoto N, Yanagibashi T, Ogasawara M, Yamamoto S, Imamura R, Takasaki I, Hara H, Sasahara M, Arita M, Hida S, Taniguchi S, Suda T, Takatsu K.

FASEB J. 2019 Jul 29:fj201900477RR. doi: 10.1096/fj.201900477RR. [Epub ahead of print]

PMID:
31355683
8.

Enhanced postprandial glucagon-like peptide-1 secretion during obesity development has a protective role against glucose intolerance induction in rats.

Pinyo J, Hira T, Hara H.

Br J Nutr. 2019 Jul 29:1-12. doi: 10.1017/S0007114519001223. [Epub ahead of print]

PMID:
31352909
9.

Gemcitabine and docetaxel combination chemotherapy for advanced bone and soft tissue sarcomas: protocol for an open-label, non-randomised, Phase 2 study.

Hara H, Kawamoto T, Fukase N, Kawakami Y, Takemori T, Fujiwara S, Kitayama K, Nishida K, Kuroda R, Akisue T.

BMC Cancer. 2019 Jul 23;19(1):725. doi: 10.1186/s12885-019-5923-7.

10.

Postoperative Changes in Lymphoscintigraphic Findings After Lymphaticovenous Anastomosis.

Hara H, Mihara M.

Ann Plast Surg. 2019 Jul 18. doi: 10.1097/SAP.0000000000001872. [Epub ahead of print]

PMID:
31335464
11.

Lymphatic Vessel Thrombosis in a Patient with Secondary Lymphedema.

Hara H, Mihara M, Ohtomo R, Tanaka S.

Plast Reconstr Surg Glob Open. 2019 May 24;7(5):e2268. doi: 10.1097/GOX.0000000000002268. eCollection 2019 May.

12.

Diagnostic value of lead aVR in electrocardiography for identifying acute coronary lesions in patients with out-of-hospital cardiac arrest.

Yamamoto M, Witsch T, Kubota S, Hara H, Hiroi Y.

Resuscitation. 2019 Jul 19;142:97-103. doi: 10.1016/j.resuscitation.2019.07.017. [Epub ahead of print]

PMID:
31330201
13.

Transmitral inflow wave and progression from paroxysmal to permanent atrial fibrillation in Asian people.

Nakagawa T, Hara H, Yamamoto M, Matsushita Y, Hiroi Y.

Heart Asia. 2019 Jun 26;11(2):e011166. doi: 10.1136/heartasia-2018-011166. eCollection 2019.

14.

Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis.

Yoshida M, Minagawa S, Araya J, Sakamoto T, Hara H, Tsubouchi K, Hosaka Y, Ichikawa A, Saito N, Kadota T, Sato N, Kurita Y, Kobayashi K, Ito S, Utsumi H, Wakui H, Numata T, Kaneko Y, Mori S, Asano H, Yamashita M, Odaka M, Morikawa T, Nakayama K, Iwamoto T, Imai H, Kuwano K.

Nat Commun. 2019 Jul 17;10(1):3145. doi: 10.1038/s41467-019-10991-7.

15.

Successful treatment of a right internal mammary artery aneurysm with thoracoscopic surgery.

Miyazaki M, Nagamine H, Hara H, Sugita H, Kawase Y.

J Vasc Surg Cases Innov Tech. 2019 Jun 25;5(3):269-272. doi: 10.1016/j.jvscit.2019.03.006. eCollection 2019 Sep.

16.

Generation and Clinical Application of Gene-Modified Autologous Epidermal Sheets in Netherton Syndrome: Lessons Learned from a Phase 1 Trial.

Di WL, Lwin SM, Petrova A, Bernadis C, Syed F, Farzaneh F, Moulding D, Martinez AE, Sebire NJ, Rampling D, Virasami A, Zamiri M, Wang W, Hara H, Kadiyirire T, Abdul-Wahab A, Martinez-Queipo M, Harper JI, McGrath JA, Thrasher AJ, Mellerio JE, Qasim W.

Hum Gene Ther. 2019 Aug 5. doi: 10.1089/hum.2019.049. [Epub ahead of print]

PMID:
31288584
17.

LIFE-SUPPORTING KIDNEY XENOTRANSPLANTATION FROM GENETICALLY-ENGINEERED PIGS IN BABOONS: A COMPARISON OF TWO IMMUNOSUPPRESSIVE REGIMENS.

Yamamoto T, Hara H, Foote J, Wang L, Li Q, Klein EC, Schuurman HJ, Zhou H, Li J, Tector AJ, Zhang Z, Ezzelarab M, Lovingood R, Ayares D, Eckhoff DE, Cooper DKC, Iwase H.

Transplantation. 2019 Jun 24. doi: 10.1097/TP.0000000000002796. [Epub ahead of print]

PMID:
31283686
18.

Elucidation of prazosin biodegradation by isolated Bacillus spp. from the tropical environment.

Mohd Mohsi NF, Apandi A, Megat Mohd Noor MJ, Md Akhir FN, Sugiura N, Utsumi M, Othman N, Zakaria Z, Hara H.

J Gen Appl Microbiol. 2019 Jul 8. doi: 10.2323/jgam.2019.04.001. [Epub ahead of print]

19.

Clinical Implication of Tumor-invasive Status into the Muscularis Propria in T2 Gastric Cancer.

Nakamura K, Ogimi M, Tomioku M, Hara H, Nabeshima K, Nomura E.

In Vivo. 2019 Jul-Aug;33(4):1341-1346. doi: 10.21873/invivo.11609.

20.

ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism.

Fang R, Uchiyama R, Sakai S, Hara H, Tsutsui H, Suda T, Mitsuyama M, Kawamura I, Tsuchiya K.

Mucosal Immunol. 2019 Jul 5. doi: 10.1038/s41385-019-0181-1. [Epub ahead of print]

PMID:
31278375
21.

A novel intracellular dextranase derived from Paenibacillus sp. 598K with an ability to degrade cycloisomaltooligosaccharides.

Mizushima D, Miyazaki T, Shiwa Y, Kimura K, Suzuki S, Fujita N, Yoshikawa H, Kimura A, Kitamura S, Hara H, Funane K.

Appl Microbiol Biotechnol. 2019 Aug;103(16):6581-6592. doi: 10.1007/s00253-019-09965-y. Epub 2019 Jul 4.

PMID:
31273396
22.

Reply to the Letter: Increased bioavailability of plasma polyphenols via the intestinal fermentation of soybean fibers: a role for gut microbiome?

Trakooncharoenvit A, Tanaka S, Mizuta E, Hira T, Hara H.

Eur J Nutr. 2019 Sep;58(6):2563. doi: 10.1007/s00394-019-02030-4. No abstract available.

PMID:
31263985
23.

Anti-VEGFR2 antibody-modified micelle for triggered drug delivery and effective therapy of choroidal neovascularization.

Takahashi K, Masuda T, Harada M, Inoue T, Nakamura S, Naito K, Hara H, Shimazawa M.

Curr Neurovasc Res. 2019 Jun 19. doi: 10.2174/1567202616666190619150956. [Epub ahead of print]

PMID:
31258081
24.

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Induced by Repeated Forced Swimming in Mice.

Ohba T, Domoto S, Tanaka M, Nakamura S, Shimazawa M, Hara H.

Biol Pharm Bull. 2019;42(7):1140-1145. doi: 10.1248/bpb.b19-00009.

25.

TAK-137, an AMPA receptor potentiator with little agonistic effect, produces antidepressant-like effect without causing psychotomimetic effects in rats.

Suzuki A, Murakami K, Tajima Y, Hara H, Kunugi A, Kimura H.

Pharmacol Biochem Behav. 2019 Aug;183:80-86. doi: 10.1016/j.pbb.2019.06.004. Epub 2019 Jun 13.

PMID:
31202810
26.

Synergistic effect of hypertension and smoking on the total small vessel disease score in healthy individuals: the Kashima scan study.

Hara M, Yakushiji Y, Suzuyama K, Nishihara M, Eriguchi M, Noguchi T, Nishiyama M, Nanri Y, Tanaka J, Hara H.

Hypertens Res. 2019 Jun 11. doi: 10.1038/s41440-019-0282-y. [Epub ahead of print]

PMID:
31182862
27.

Prostaglandin E-Major Urinary Metabolite (PGE-MUM) as a Tumor Marker for Lung Adenocarcinoma.

Kawamoto H, Hara H, Araya J, Ichikawa A, Fujita Y, Utsumi H, Hashimoto M, Wakui H, Minagawa S, Numata T, Arihiro S, Matsuura T, Fujiwara M, Ito S, Kuwano K.

Cancers (Basel). 2019 Jun 3;11(6). pii: E768. doi: 10.3390/cancers11060768.

28.

Systemic chemotherapy for gastric cancer with early recurrence after adjuvant S-1 monotherapy: a multicenter retrospective study.

Mitani S, Kadowaki S, Hasegawa H, Wakatsuki T, Hara H, Tajika M, Nishikawa K, Hirao M, Takahari D, Chin K, Muro K.

Int J Clin Oncol. 2019 May 31. doi: 10.1007/s10147-019-01477-z. [Epub ahead of print]

PMID:
31152323
29.

Evidence for the important role of inflammation in xenotransplantation.

Li J, Hara H, Wang Y, Esmon C, Cooper DKC, Iwase H.

J Inflamm (Lond). 2019 May 28;16:10. doi: 10.1186/s12950-019-0213-3. eCollection 2019. Review.

30.

Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies.

Wilson D, Ambler G, Lee KJ, Lim JS, Shiozawa M, Koga M, Li L, Lovelock C, Chabriat H, Hennerici M, Wong YK, Mak HKF, Prats-Sánchez L, Martínez-Domeño A, Inamura S, Yoshifuji K, Arsava EM, Horstmann S, Purrucker J, Lam BYK, Wong A, Kim YD, Song TJ, Schrooten M, Lemmens R, Eppinger S, Gattringer T, Uysal E, Tanriverdi Z, Bornstein NM, Assayag EB, Hallevi H, Tanaka J, Hara H, Coutts SB, Hert L, Polymeris A, Seiffge DJ, Lyrer P, Algra A, Kappelle J, Al-Shahi Salman R, Jäger HR, Lip GYH, Mattle HP, Panos LD, Mas JL, Legrand L, Karayiannis C, Phan T, Gunkel S, Christ N, Abrigo J, Leung T, Chu W, Chappell F, Makin S, Hayden D, Williams DJ, Kooi ME, van Dam-Nolen DHK, Barbato C, Browning S, Wiegertjes K, Tuladhar AM, Maaijwee N, Guevarra C, Yatawara C, Mendyk AM, Delmaire C, Köhler S, van Oostenbrugge R, Zhou Y, Xu C, Hilal S, Gyanwali B, Chen C, Lou M, Staals J, Bordet R, Kandiah N, de Leeuw FE, Simister R, van der Lugt A, Kelly PJ, Wardlaw JM, Soo Y, Fluri F, Srikanth V, Calvet D, Jung S, Kwa VIH, Engelter ST, Peters N, Smith EE, Yakushiji Y, Orken DN, Fazekas F, Thijs V, Heo JH, Mok V, Veltkamp R, Ay H, Imaizumi T, Gomez-Anson B, Lau KK, Jouvent E, Rothwell PM, Toyoda K, Bae HJ, Marti-Fabregas J, Werring DJ; Microbleeds International Collaborative Network.

Lancet Neurol. 2019 Jul;18(7):653-665. doi: 10.1016/S1474-4422(19)30197-8. Epub 2019 May 23. Erratum in: Lancet Neurol. 2019 Sep;18(9):e8.

31.

The Protective Effects of Levetiracetam on a Human iPSCs-Derived Spinal Muscular Atrophy Model.

Ando S, Funato M, Ohuchi K, Inagaki S, Sato A, Seki J, Kawase C, Saito T, Nishio H, Nakamura S, Shimazawa M, Kaneko H, Hara H.

Neurochem Res. 2019 Jul;44(7):1773-1779. doi: 10.1007/s11064-019-02814-4. Epub 2019 May 17.

PMID:
31102025
32.

Docetaxel plus cisplatin and S-1 versus cisplatin and S-1 in patients with advanced gastric cancer (JCOG1013): an open-label, phase 3, randomised controlled trial.

Yamada Y, Boku N, Mizusawa J, Iwasa S, Kadowaki S, Nakayama N, Azuma M, Sakamoto T, Shitara K, Tamura T, Chin K, Hata H, Nakamori M, Hara H, Yasui H, Katayama H, Fukuda H, Yoshikawa T, Sasako M, Terashima M.

Lancet Gastroenterol Hepatol. 2019 Jul;4(7):501-510. doi: 10.1016/S2468-1253(19)30083-4. Epub 2019 May 14.

PMID:
31101534
33.

Tracking and clarifying differential traits of classical- and atypical L-type bovine spongiform encephalopathy prions after transmission from cattle to cynomolgus monkeys.

Hagiwara K, Sato Y, Yamakawa Y, Hara H, Tobiume M, Okemoto-Nakamura Y, Sata T, Horiuchi M, Shibata H, Ono F.

PLoS One. 2019 May 16;14(5):e0216807. doi: 10.1371/journal.pone.0216807. eCollection 2019.

34.

A case of prominent coronary plaque regression with statin therapy.

Awaya T, Kodama C, Yamamoto M, Okazaki O, Hara H, Hiroi Y, Moroi M.

J Cardiovasc Comput Tomogr. 2019 May 3. pii: S1934-5925(19)30004-8. doi: 10.1016/j.jcct.2019.05.002. [Epub ahead of print] No abstract available.

35.

Water-soluble dietary fibers enhance bioavailability of quercetin and a fiber derived from soybean is most effective after long-term feeding in rats.

Trakooncharoenvit A, Tanaka S, Mizuta E, Hira T, Hara H.

Eur J Nutr. 2019 May 11. doi: 10.1007/s00394-019-01992-9. [Epub ahead of print]

PMID:
31079173
36.

Circulating pig-specific DNA as a novel biomarker for monitoring xenograft rejection.

Zhou M, Lu Y, Zhao C, Zhang J, Cooper DKC, Xie C, Song Z, Gao H, Qu Z, Lin S, Deng Y, Hara H, Zhan Y, Jiang Z, Dai Y, Wu C, Cai Z, Mou L.

Xenotransplantation. 2019 May 11:e12522. doi: 10.1111/xen.12522. [Epub ahead of print]

PMID:
31077480
37.

Nrf2 Activator RS9 Suppresses Pathological Ocular Angiogenesis and Hyperpermeability.

Nakamura S, Noguchi T, Inoue Y, Sakurai S, Nishinaka A, Hida Y, Masuda T, Nakagami Y, Horai N, Tsusaki H, Hara H, Shimazawa M.

Invest Ophthalmol Vis Sci. 2019 May 1;60(6):1943-1952. doi: 10.1167/iovs.18-25745.

PMID:
31050722
38.

VGF has Roles in the Pathogenesis of Major Depressive Disorder and Schizophrenia: Evidence from Transgenic Mouse Models.

Mizoguchi T, Hara H, Shimazawa M.

Cell Mol Neurobiol. 2019 Aug;39(6):721-727. doi: 10.1007/s10571-019-00681-9. Epub 2019 Apr 29. Review.

PMID:
31037515
39.

The complex functioning of the complement system in xenotransplantation.

Zhou H, Hara H, Cooper DKC.

Xenotransplantation. 2019 Apr 29:e12517. doi: 10.1111/xen.12517. [Epub ahead of print] Review.

PMID:
31033064
40.

Intranodal Lymphatic Embolization for Chylocolporrhea Caused by Chylous Reflux Syndrome in Noonan Syndrome.

Yamamoto M, Kondo H, Shigeru F, Inui S, Mihara M, Hara H, Oba H.

J Vasc Interv Radiol. 2019 May;30(5):769-772. doi: 10.1016/j.jvir.2018.08.033. No abstract available.

PMID:
31029393
41.

Bacterial Flora in the Genital Area of Patients with Lower Limb Lymphedema.

Hara H, Mihara M.

Lymphat Res Biol. 2019 Apr 24. doi: 10.1089/lrb.2018.0069. [Epub ahead of print]

PMID:
31021264
42.

Microbial Diversity in Decaying Oil Palm Empty Fruit Bunches (OPEFB) and Isolation of Lignin-degrading Bacteria from a Tropical Environment.

Tahir AA, Mohd Barnoh NF, Yusof N, Mohd Said NN, Utsumi M, Yen AM, Hashim H, Mohd Noor MJM, Akhir FNM, Mohamad SE, Sugiura N, Othman N, Zakaria Z, Hara H.

Microbes Environ. 2019 Jun 27;34(2):161-168. doi: 10.1264/jsme2.ME18117. Epub 2019 Apr 23.

43.

Intracellular Fe2+ accumulation in endothelial cells and pericytes induces blood-brain barrier dysfunction in secondary brain injury after brain hemorrhage.

Imai T, Iwata S, Hirayama T, Nagasawa H, Nakamura S, Shimazawa M, Hara H.

Sci Rep. 2019 Apr 17;9(1):6228. doi: 10.1038/s41598-019-42370-z.

44.

Justification of specific genetic modifications in pigs for clinical organ xenotransplantation.

Cooper DKC, Hara H, Iwase H, Yamamoto T, Li Q, Ezzelarab M, Federzoni E, Dandro A, Ayares D.

Xenotransplantation. 2019 Apr 15:e12516. doi: 10.1111/xen.12516. [Epub ahead of print]

PMID:
30989742
45.

Microdeletion in Xq28 with a polymorphic inversion in a patient with FLNA-associated progressive lung disease.

Yoshii K, Matsumoto H, Hirasawa K, Sakauchi M, Hara H, Ito S, Osawa M, Fukami M, Horikawa R, Nagata S.

Respir Investig. 2019 Jul;57(4):395-398. doi: 10.1016/j.resinv.2019.02.008. Epub 2019 Apr 12.

PMID:
30987847
46.

Activation of extracytoplasmic function sigma factors upon removal of glucolipids and reduction of phosphatidylglycerol content in Bacillus subtilis cells lacking lipoteichoic acid.

Seki T, Furumi T, Hashimoto M, Hara H, Matsuoka S.

Genes Genet Syst. 2019 Apr 27;94(2):71-80. doi: 10.1266/ggs.18-00046. Epub 2019 Apr 9.

47.

The "Baby Fae" baboon heart transplant-Potential cause of rejection.

Cooper DKC, Hara H, Banks CA, Cleveland D, Iwase H.

Xenotransplantation. 2019 Apr 1:e12511. doi: 10.1111/xen.12511. [Epub ahead of print] No abstract available.

PMID:
30932224
48.

Renal Vein Thrombosis After Open Repair of Abdominal Aortic Aneurysm Successfully Treated by Direct Oral Anticoagulants.

Date Y, Nagamine H, Hara H, Kawase Y.

Vasc Endovascular Surg. 2019 Jul;53(5):408-410. doi: 10.1177/1538574419839251. Epub 2019 Mar 26.

PMID:
30913995
49.

Pembrolizumab alone or in combination with chemotherapy as first-line therapy for patients with advanced gastric or gastroesophageal junction adenocarcinoma: results from the phase II nonrandomized KEYNOTE-059 study.

Bang YJ, Kang YK, Catenacci DV, Muro K, Fuchs CS, Geva R, Hara H, Golan T, Garrido M, Jalal SI, Borg C, Doi T, Yoon HH, Savage MJ, Wang J, Dalal RP, Shah S, Wainberg ZA, Chung HC.

Gastric Cancer. 2019 Jul;22(4):828-837. doi: 10.1007/s10120-018-00909-5. Epub 2019 Mar 25.

50.

Post-stroke pain caused by peripheral sensory hypersensitization after transient focal cerebral ischemia in rats.

Hyakkoku K, Umeda N, Shimada S, Imai T, Morioka Y, Sakaguchi G, Hara H.

Brain Res. 2019 Jul 15;1715:35-40. doi: 10.1016/j.brainres.2019.03.019. Epub 2019 Mar 18.

PMID:
30898673

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