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Items: 1 to 50 of 3033

1.

Contribution of platelet-derived growth factor signaling to retina regeneration in zebrafish.

Saito Y, Yamaguchi A, Nakamura S, Okuyoshi H, Shimazawa M, Hara H.

Neurosci Lett. 2020 Apr 3:134930. doi: 10.1016/j.neulet.2020.134930. [Epub ahead of print]

PMID:
32251708
2.

Blue light-emitting diode irradiation promotes transcription factor EB-mediated lysosome biogenesis and lysosomal cell death in murine photoreceptor-derived cells.

Otsu W, Ishida K, Nakamura S, Shimazawa M, Tsusaki H, Hara H.

Biochem Biophys Res Commun. 2020 Mar 28. pii: S0006-291X(20)30609-4. doi: 10.1016/j.bbrc.2020.03.118. [Epub ahead of print]

PMID:
32234235
3.

Lysyl oxidase expression is regulated by the H3K27 demethylase Jmjd3 in tumor-associated M2-like macrophages.

Takemoto R, Kamiya T, Hara H, Adachi T.

J Clin Biochem Nutr. 2020 Mar;66(2):110-115. doi: 10.3164/jcbn.19-67. Epub 2020 Feb 8.

4.

The Xiphydria annulitibia group in northeastern Asia (Hymenoptera, Xiphydriidae).

Shinohara A, Hara H, Smith DR.

Zootaxa. 2020 Mar 24;4755(2):zootaxa.4755.2.11. doi: 10.11646/zootaxa.4755.2.11.

PMID:
32230189
5.

Low-Dose Phosphodiesterase III Inhibitor Reduces the Vascular Amyloid Burden in Amyloid-β Protein Precursor Transgenic Mice.

Yakushiji Y, Kawamoto K, Uchihashi K, Ihara M, Aoki S, Nagaishi Y, Suzuyama K, Tsugitomi Y, Hara H.

Int J Mol Sci. 2020 Mar 26;21(7). pii: E2295. doi: 10.3390/ijms21072295.

6.

Effects of anti-osteoporosis drugs against dexamethasone-induced osteoporosis-like phenotype using a zebrafish scale-regeneration model.

Saito Y, Nakamura S, Chinen N, Shimazawa M, Hara H.

J Pharmacol Sci. 2020 Mar 9. pii: S1347-8613(20)30027-X. doi: 10.1016/j.jphs.2020.02.011. [Epub ahead of print]

7.

Nasal vaccine delivery attenuates brain pathology and cognitive impairment in tauopathy model mice.

Takeuchi H, Imamura K, Ji B, Tsukita K, Enami T, Takao K, Miyakawa T, Hasegawa M, Sahara N, Iwata N, Inoue M, Hara H, Tabira T, Ono M, Trojanowski JQ, Lee VM, Takahashi R, Suhara T, Higuchi M, Inoue H.

NPJ Vaccines. 2020 Mar 24;5:28. doi: 10.1038/s41541-020-0172-y. eCollection 2020.

8.

A triterpenoid Nrf2 activator, RS9, promotes LC3-associated phagocytosis of photoreceptor outer segments in a p62-independent manner.

Saito Y, Yako T, Otsu W, Nakamura S, Inoue Y, Muramatsu A, Nakagami Y, Shimazawa M, Hara H.

Free Radic Biol Med. 2020 Mar 23;152:235-247. doi: 10.1016/j.freeradbiomed.2020.03.012. [Epub ahead of print]

PMID:
32217192
9.

Identification of VGF nerve growth factor inducible-producing cells in human spinal cords and expression change in patients with amyotrophic lateral sclerosis.

Noda Y, Tanaka M, Nakamura S, Ito J, Kakita A, Hara H, Shimazawa M.

Int J Med Sci. 2020 Feb 4;17(4):480-489. doi: 10.7150/ijms.39101. eCollection 2020.

10.

Riluzole enhances the antitumor effects of temozolomide via suppression of MGMT expression in glioblastoma.

Yamada T, Tsuji S, Nakamura S, Egashira Y, Shimazawa M, Nakayama N, Yano H, Iwama T, Hara H.

J Neurosurg. 2020 Mar 13:1-10. doi: 10.3171/2019.12.JNS192682. [Epub ahead of print]

PMID:
32168477
11.

Long-term efficacy and predictive correlates of response to nivolumab in Japanese patients with esophageal cancer.

Kato K, Doki Y, Ura T, Hamamoto Y, Kojima T, Tsushima T, Hironaka S, Hara H, Kudo T, Iwasa S, Muro K, Yasui H, Minashi K, Yamaguchi K, Ohtsu A, Kitagawa Y.

Cancer Sci. 2020 Mar 11. doi: 10.1111/cas.14380. [Epub ahead of print]

12.

Prognostic Impact of Postoperative Complications following Salvage Esophagectomy for Esophageal Cancer after Definitive Chemoradiotherapy.

Sugimura K, Miyata H, Shinno N, Ushigome H, Asukai K, Hara H, Hasegawa S, Yamada D, Yamamoto K, Haraguchi N, Nishimura J, Motoori M, Wada H, Takahashi H, Yasui M, Omori T, Ohue M, Yano M.

Oncology. 2020 Mar 10:1-9. doi: 10.1159/000505925. [Epub ahead of print]

PMID:
32155643
13.

Anti-glypican-1 antibody-drug conjugate is a potential therapy against pancreatic cancer.

Nishigaki T, Takahashi T, Serada S, Fujimoto M, Ohkawara T, Hara H, Sugase T, Otsuru T, Saito Y, Tsujii S, Nomura T, Tanaka K, Miyazaki Y, Makino T, Kurokawa Y, Nakajima K, Eguchi H, Yamasaki M, Mori M, Doki Y, Naka T.

Br J Cancer. 2020 Mar 10. doi: 10.1038/s41416-020-0781-2. [Epub ahead of print]

PMID:
32152502
14.

Retrospective analysis of high-dose chemotherapy followed by autologous stem cell transplantation for high-risk pediatric osteosarcoma.

Uemura S, Mori T, Ishiko S, Takafuji S, Nino N, Yamamoto N, Hayakawa A, Nishimura N, Hara H, Kawamoto T, Akisue T, Iijima K.

Pediatr Hematol Oncol. 2020 Mar 10:1-7. doi: 10.1080/08880018.2020.1729906. [Epub ahead of print]

PMID:
32151185
15.

Decreased CT-number in the pancreatic parenchyma is a reliable imaging biomarker of the presence of malignancies in patients with high-risk intraductal papillary mucinous neoplasm.

Abe T, Yamada D, Asukai K, Hasegawa S, Tomokuni A, Wada H, Fujii W, Ikezawa K, Fukutake N, Ohkawa K, Shinno N, Hara H, Yanagimoto Y, Takahashi Y, Sugimura K, Yamamoto K, Ushigome H, Haraguchi N, Nishimura J, Yasui M, Omori T, Miyata H, Ohue M, Yano M, Sakon M, Takahashi H.

Pancreatology. 2020 Feb 21. pii: S1424-3903(20)30050-8. doi: 10.1016/j.pan.2020.02.014. [Epub ahead of print]

PMID:
32146046
16.

Safety and efficacy of pembrolizumab in combination with S-1 plus oxaliplatin as a first-line treatment in patients with advanced gastric/gastroesophageal junction cancer: Cohort 1 data from the KEYNOTE-659 phase IIb study.

Kawazoe A, Yamaguchi K, Yasui H, Negoro Y, Azuma M, Amagai K, Hara H, Baba H, Tsuda M, Hosaka H, Kawakami H, Oshima T, Omuro Y, Machida N, Esaki T, Yoshida K, Nishina T, Komatsu Y, Han SR, Shiratori S, Shitara K.

Eur J Cancer. 2020 Apr;129:97-106. doi: 10.1016/j.ejca.2020.02.002. Epub 2020 Mar 4.

17.

Rapid improvements in charge carrier mobility at ionic liquid/pentacene single crystal interfaces by self-cleaning.

Morino Y, Yokota Y, Hara H, Bando KI, Ono S, Imanishi A, Okada Y, Matsui H, Uemura T, Takeya J, Fukui KI.

Phys Chem Chem Phys. 2020 Mar 18;22(11):6131-6135. doi: 10.1039/d0cp00149j.

PMID:
32124891
18.

Multilymphosome injection indocyanine green lymphography can detect more lymphatic vessels than lymphoscintigraphy in lymphedematous limbs.

Hara H, Mihara M.

J Plast Reconstr Aesthet Surg. 2020 Jan 21. pii: S1748-6815(20)30041-3. doi: 10.1016/j.bjps.2020.01.021. [Epub ahead of print]

PMID:
32115379
19.

Effect of venous reflux on the surgical result of lymphaticovenous anastomosis.

Hara H, Mihara M.

J Plast Reconstr Aesthet Surg. 2020 Feb 18. pii: S1748-6815(20)30074-7. doi: 10.1016/j.bjps.2020.02.015. [Epub ahead of print] No abstract available.

PMID:
32113965
20.

The year in review 2019: Coronary interventions.

Gao C, Wang R, Sharif F, Takahashi K, Ono M, Hara H, Tomaniak M, Kawashima H, Modolo R, van Geuns RM, Capodanno D, Byrne RA, Wijns W, Onuma Y, Serruys PW.

EuroIntervention. 2020 Feb 25. pii: EIJ-D-19-01124. doi: 10.4244/EIJ-D-19-01124. [Epub ahead of print] No abstract available.

21.

Efficacy and Safety of OnabotulinumtoxinA 400 Units in Patients with Post-Stroke Upper Limb Spasticity: Final Report of a Randomized, Double-Blind, Placebo-Controlled Trial with an Open-Label Extension Phase.

Abo M, Shigematsu T, Hara H, Matsuda Y, Nimura A, Yamashita Y, Takahashi K.

Toxins (Basel). 2020 Feb 18;12(2). pii: E127. doi: 10.3390/toxins12020127.

22.

A phase III study of TAS-118 plus oxaliplatin versus S-1 plus cisplatin as first-line chemotherapy in patients with advanced gastric cancer (SOLAR study).

Kang Y, Chin K, Chung H, Kadowaki S, Oh S, Nakayama N, Lee K, Hara H, Chung I, Tsuda M, Park S, Hosaka H, Hironaka S, Miyata Y, Ryu M, Takeuchi M, Baba H, Hyodo I, Bang Y, Boku N.

Ann Oncol. 2019 Jul;30 Suppl 4:iv153. doi: 10.1093/annonc/mdz183.002. Epub 2019 Dec 4. No abstract available.

PMID:
32085056
23.

Regorafenib plus nivolumab in patients with advanced colorectal or gastric cancer: an open-label, dose-finding, and dose-expansion phase 1b trial (REGONIVO, EPOC1603).

Hara H, Fukuoka S, Takahashi N, Kojima T, Kawazoe A, Asayama M, Yoshii T, Kotani D, Tamura H, Mikamoto Y, Sugama A, Wakabayashi M, Nomura S, Sato A, Togashi Y, Nishikawa H, Shitara K.

Ann Oncol. 2019 Jul;30 Suppl 4:iv124. doi: 10.1093/annonc/mdz157.006. Epub 2019 Dec 4. No abstract available.

PMID:
32085012
24.

Total small vessel disease score and cerebro-cardiovascular events in healthy adults: The Kashima scan study.

Suzuyama K, Yakushiji Y, Ogata A, Nishihara M, Eriguchi M, Kawaguchi A, Noguchi T, Nakajima J, Hara H.

Int J Stroke. 2020 Feb 19:1747493020908144. doi: 10.1177/1747493020908144. [Epub ahead of print]

PMID:
32075572
25.

Pressure-induced superconductivity in SnSb2Te4.

Song P, Matsumoto R, Hou Z, Adachi S, Hara H, Saito Y, Castro PB, Takeya H, Takano Y.

J Phys Condens Matter. 2020 Feb 17;32(23):235901. doi: 10.1088/1361-648X/ab76e2. [Epub ahead of print]

PMID:
32066132
26.

Proteomic Characterization of Lignocellulolytic Enzymes Secreted by the Insect-Associated Fungus Daldinia decipiens oita, Isolated from a Forest in Northern Japan.

Hori C, Song R, Matsumoto K, Matsumoto R, Minkoff BB, Oita S, Hara H, Takasuka TE.

Appl Environ Microbiol. 2020 Apr 1;86(8). pii: e02350-19. doi: 10.1128/AEM.02350-19. Print 2020 Apr 1.

PMID:
32060026
27.

Levetiracetam, an Antiepileptic Drug has Neuroprotective Effects on Intracranial Hemorrhage Injury.

Imai T, Sugiyama T, Iwata S, Nakamura S, Shimazawa M, Hara H.

Neuroscience. 2020 Apr 1;431:25-33. doi: 10.1016/j.neuroscience.2020.01.036. Epub 2020 Feb 11.

PMID:
32058064
28.

Removal efficiency of Gram-positive and Gram-negative bacteria using a natural coagulant during coagulation, flocculation, and sedimentation processes.

Sha'arani S, Azizan SNF, Md Akhir FN, Muhammad Yuzir MA, Othman N, Zakaria Z, Mohd Noor MJM, Hara H.

Water Sci Technol. 2019 Nov;80(9):1787-1795. doi: 10.2166/wst.2019.433.

PMID:
32039910
29.

Randomized phase II/III study of 5-fluorouracil/l-leucovorin versus 5-fluorouracil/l-leucovorin plus paclitaxel administered to patients with severe peritoneal metastases of gastric cancer (JCOG1108/WJOG7312G).

Nakajima TE, Yamaguchi K, Boku N, Hyodo I, Mizusawa J, Hara H, Nishina T, Sakamoto T, Shitara K, Shinozaki K, Katayama H, Nakamura S, Muro K, Terashima M.

Gastric Cancer. 2020 Feb 8. doi: 10.1007/s10120-020-01043-x. [Epub ahead of print]

PMID:
32036492
30.

Indoleamine 2,3-dioxygenase 1 is highly expressed in glioma stem cells.

Ozawa Y, Yamamuro S, Sano E, Tatsuoka J, Hanashima Y, Yoshimura S, Sumi K, Hara H, Nakayama T, Suzuki Y, Yoshino A.

Biochem Biophys Res Commun. 2020 Apr 9;524(3):723-729. doi: 10.1016/j.bbrc.2020.01.148. Epub 2020 Feb 5.

31.

Potential effects of progranulin and granulins against retinal photoreceptor cell degeneration.

Tanaka M, Kuse Y, Nakamura S, Hara H, Shimazawa M.

Mol Vis. 2019 Dec 31;25:902-911. eCollection 2019.

32.

Regulated Necrosis in Pulmonary Disease: A Focus on Necroptosis and Ferroptosis.

Minagawa S, Yoshida M, Araya J, Hara H, Imai H, Kuwano K.

Am J Respir Cell Mol Biol. 2020 Feb 4. doi: 10.1165/rcmb.2019-0337TR. [Epub ahead of print]

PMID:
32017592
33.

The association of body mass index with long-term clinical outcomes after ticagrelor monotherapy following abbreviated dual antiplatelet therapy in patients undergoing percutaneous coronary intervention: a prespecified sub-analysis of the GLOBAL LEADERS Trial.

Ono M, Chichareon P, Tomaniak M, Kawashima H, Takahashi K, Kogame N, Modolo R, Hara H, Gao C, Wang R, Walsh S, Suryapranata H, da Silva PC, Cotton J, Koning R, Akin I, Rensing BJWM, Garg S, Wykrzykowska JJ, Piek JJ, Jüni P, Hamm C, Steg PG, Valgimigli M, Windecker S, Storey RF, Onuma Y, Vranckx P, Serruys PW.

Clin Res Cardiol. 2020 Jan 31. doi: 10.1007/s00392-020-01604-1. [Epub ahead of print]

34.

Complete Genome Sequence of Lignin-Degrading Streptomyces sp. Strain S6, Isolated from an Oil Palm Plantation in Malaysia.

Yusof N, Abdullah Tahir A, Riyadi FA, Ahmad Sabri NS, Md Akhir FN, Othman N, Chin KL, Tseng KY, Chin ST, Zakaria Z, Lai CY, Hara H.

Microbiol Resour Announc. 2020 Jan 30;9(5). pii: e01332-19. doi: 10.1128/MRA.01332-19.

35.

A phase II trial of everolimus in patients with advanced pancreatic neuroendocrine carcinoma refractory or intolerant to platinum-containing chemotherapy (NECTOR trial).

Okuyama H, Ikeda M, Okusaka T, Furukawa M, Ohkawa S, Hosokawa A, Kojima Y, Hara H, Murohisa G, Shioji K, Asagi A, Mizuno N, Kojima M, Yamanaka T, Furuse J.

Neuroendocrinology. 2020 Jan 2. doi: 10.1159/000505550. [Epub ahead of print]

36.

Plasma vasohibin-1 and vasohibin-2 are useful biomarkers in patients with esophageal squamous cell carcinoma.

Yamamoto M, Ozawa S, Ninomiya Y, Koyanagi K, Oguma J, Kazuno A, Hara H, Yatabe K, Kajiwara H, Nakamura N, Sato Y.

Esophagus. 2020 Jan 24. doi: 10.1007/s10388-020-00719-8. [Epub ahead of print]

PMID:
31980976
37.

Patient-reported symptom burden as a prognostic factor in treatment with first-line cetuximab plus chemotherapy for unresectable metastatic colorectal cancer: Results of Phase II QUACK trial.

Ooki A, Morita S, Iwamoto S, Hara H, Tanioka H, Satake H, Kataoka M, Kotaka M, Kagawa Y, Nakamura M, Shingai T, Ishikawa M, Miyake Y, Suto T, Hashiguchi Y, Yabuno T, Sakamoto J, Tsuji A, Ando M, Yamaguchi K.

Cancer Med. 2020 Mar;9(5):1779-1789. doi: 10.1002/cam4.2826. Epub 2020 Jan 21.

38.

Impact of renal function on clinical outcomes after PCI in ACS and stable CAD patients treated with ticagrelor: a prespecified analysis of the GLOBAL LEADERS randomized clinical trial.

Tomaniak M, Chichareon P, Klimczak-Tomaniak D, Takahashi K, Kogame N, Modolo R, Wang R, Ono M, Hara H, Gao C, Kawashima H, Rademaker-Havinga T, Garg S, Curzen N, Haude M, Kochman J, Gori T, Montalescot G, Angiolillo DJ, Capodanno D, Storey RF, Hamm C, Vranckx P, Valgimigli M, Windecker S, Onuma Y, Serruys PW, Anderson R.

Clin Res Cardiol. 2020 Jan 10. doi: 10.1007/s00392-019-01586-9. [Epub ahead of print]

PMID:
31925529
39.

Oral and ocular administration of crocetin prevents retinal edema in a murine retinal vein occlusion model.

Nitta K, Nishinaka A, Hida Y, Nakamura S, Shimazawa M, Hara H.

Mol Vis. 2019 Dec 26;25:859-868. eCollection 2019.

40.

Treating and preventing recurrence of recurrent genital acquired lymphangiectasia using lymphaticovenous anastomosis at genital area: A case report.

Hara H, Mihara M.

Microsurgery. 2020 Mar;40(3):399-403. doi: 10.1002/micr.30552. Epub 2020 Jan 6.

PMID:
31904132
41.

Discovery of a Novel, Highly Potent, and Selective Thieno[3,2-d]pyrimidinone-Based Cdc7 Inhibitor with a Quinuclidine Moiety (TAK-931) as an Orally Active Investigational Antitumor Agent.

Kurasawa O, Miyazaki T, Homma M, Oguro Y, Imada T, Uchiyama N, Iwai K, Yamamoto Y, Ohori M, Hara H, Sugimoto H, Iwata K, Skene R, Hoffman I, Ohashi A, Nomura T, Cho N.

J Med Chem. 2020 Feb 13;63(3):1084-1104. doi: 10.1021/acs.jmedchem.9b01427. Epub 2020 Jan 14.

PMID:
31895562
42.

Piezo channel plays a part in retinal ganglion cell damage.

Morozumi W, Inagaki S, Iwata Y, Nakamura S, Hara H, Shimazawa M.

Exp Eye Res. 2020 Feb;191:107900. doi: 10.1016/j.exer.2019.107900. Epub 2019 Dec 23.

PMID:
31874142
43.

Erratum: Publisher Correction: A TonB-dependent receptor constitutes the outer membrane transport system for a lignin-derived aromatic compound.

Fujita M, Mori K, Hara H, Hishiyama S, Kamimura N, Masai E.

Commun Biol. 2019 Dec 17;2:476. doi: 10.1038/s42003-019-0724-8. eCollection 2019.

44.

Botulinum Toxin Therapy Combined with Rehabilitation for Stroke: A Systematic Review of Effect on Motor Function.

Hara T, Momosaki R, Niimi M, Yamada N, Hara H, Abo M.

Toxins (Basel). 2019 Dec 5;11(12). pii: E707. doi: 10.3390/toxins11120707. Review.

45.

Chemoradiotherapy with FOLFOX for esophageal squamous cell cancer with synchronous rectal cancer: Four case reports and a literature review.

Yoshii T, Hara H, Asayama M, Kumekawa Y, Miyazawa S, Takahashi N, Matsushima T, Shimizu S, Saito Y.

Mol Clin Oncol. 2020 Jan;12(1):23-30. doi: 10.3892/mco.2019.1945. Epub 2019 Oct 31.

46.

Crystal Growth, Structural Analysis, and Pressure-Induced Superconductivity in a AgIn5Se8 Single Crystal Explored by a Data-Driven Approach.

Matsumoto R, Hou Z, Hara H, Adachi S, Tanaka H, Yamamoto S, Saito Y, Takeya H, Irifune T, Terakura K, Takano Y.

Inorg Chem. 2020 Jan 6;59(1):325-331. doi: 10.1021/acs.inorgchem.9b02295. Epub 2019 Dec 9.

PMID:
31814391
47.

Generation of novel Il2rg-knockout mice with Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and Cas9.

Byambaa S, Uosaki H, Hara H, Nagao Y, Abe T, Shibata H, Nureki O, Ohmori T, Hanazono Y.

Exp Anim. 2019 Dec 4. doi: 10.1538/expanim.19-0120. [Epub ahead of print]

48.

A TonB-dependent receptor constitutes the outer membrane transport system for a lignin-derived aromatic compound.

Fujita M, Mori K, Hara H, Hishiyama S, Kamimura N, Masai E.

Commun Biol. 2019 Nov 22;2:432. doi: 10.1038/s42003-019-0676-z. eCollection 2019. Erratum in: Commun Biol. 2019 Dec 17;2:476.

49.

Clinical Pig Kidney Xenotransplantation: How Close Are We?

Cooper DKC, Hara H, Iwase H, Yamamoto T, Jagdale A, Kumar V, Mannon RB, Hanaway MJ, Anderson DJ, Eckhoff DE.

J Am Soc Nephrol. 2020 Jan;31(1):12-21. doi: 10.1681/ASN.2019070651. Epub 2019 Dec 2.

PMID:
31792154
50.

Prospective, comparative study of cemented, smooth-surfaced titanium stems and polish-surfaced, stainless steel stems at a minimum follow-up of 10 years.

Fujita H, Hara H, Harada H, Kataoka M, Tominaga T, Nishimura R.

Eur J Orthop Surg Traumatol. 2020 Apr;30(3):501-512. doi: 10.1007/s00590-019-02597-y. Epub 2019 Nov 18.

PMID:
31741055

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