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Items: 16


Streptococcal Endo-β-N-Acetylglucosaminidase Suppresses Antibody-Mediated Inflammation In Vivo.

Nandakumar KS, Collin M, Happonen KE, Lundström SL, Croxford AM, Xu B, Zubarev RA, Rowley MJ, Blom AM, Kjellman C, Holmdahl R.

Front Immunol. 2018 Jul 16;9:1623. doi: 10.3389/fimmu.2018.01623. eCollection 2018.


Diminished airway macrophage expression of the Axl receptor tyrosine kinase is associated with defective efferocytosis in asthma.

Grabiec AM, Denny N, Doherty JA, Happonen KE, Hankinson J, Connolly E, Fife ME, Fujimori T, Fujino N, Goenka A, Holden S, Tavernier G, Shah R, Cook PC, MacDonald AS, Niven RM, Dahlbäck B, Fowler SJ, Simpson A, Hussell T.

J Allergy Clin Immunol. 2017 Oct;140(4):1144-1146.e4. doi: 10.1016/j.jaci.2017.03.024. Epub 2017 Apr 12. No abstract available.


The Gas6-Axl Protein Interaction Mediates Endothelial Uptake of Platelet Microparticles.

Happonen KE, Tran S, Mörgelin M, Prince R, Calzavarini S, Angelillo-Scherrer A, Dahlbäck B.

J Biol Chem. 2016 May 13;291(20):10586-601. doi: 10.1074/jbc.M115.699058. Epub 2016 Mar 22.


Sphingosine 1-phosphate and its carrier apolipoprotein M in human sepsis and in Escherichia coli sepsis in baboons.

Frej C, Linder A, Happonen KE, Taylor FB, Lupu F, Dahlbäck B.

J Cell Mol Med. 2016 Jun;20(6):1170-81. doi: 10.1111/jcmm.12831. Epub 2016 Mar 17.


Gas6 fueling tumor-mediated thrombosis.

Happonen KE, Dahlbäck B.

Blood. 2016 Feb 11;127(6):672-3. doi: 10.1182/blood-2015-12-683474. No abstract available.


Quantification of sphingosine 1-phosphate by validated LC-MS/MS method revealing strong correlation with apolipoprotein M in plasma but not in serum due to platelet activation during blood coagulation.

Frej C, Andersson A, Larsson B, Guo LJ, Norström E, Happonen KE, Dahlbäck B.

Anal Bioanal Chem. 2015 Nov;407(28):8533-42. doi: 10.1007/s00216-015-9008-4. Epub 2015 Sep 16.


RAB24 facilitates clearance of autophagic compartments during basal conditions.

Ylä-Anttila P, Mikkonen E, Happonen KE, Holland P, Ueno T, Simonsen A, Eskelinen EL.

Autophagy. 2015;11(10):1833-48. doi: 10.1080/15548627.2015.1086522.


Serglycin is implicated in the promotion of aggressive phenotype of breast cancer cells.

Korpetinou A, Skandalis SS, Moustakas A, Happonen KE, Tveit H, Prydz K, Labropoulou VT, Giannopoulou E, Kalofonos HP, Blom AM, Karamanos NK, Theocharis AD.

PLoS One. 2013 Oct 31;8(10):e78157. doi: 10.1371/journal.pone.0078157. eCollection 2013.


COMP-C3b complexes in rheumatoid arthritis with severe extraarticular manifestations.

Happonen KE, Saxne T, Jacobsson L, Sturfelt G, Rönnelid J, Mollnes TE, Heinegård D, Turesson C, Blom AM.

J Rheumatol. 2013 Dec;40(12):2001-5. doi: 10.3899/jrheum.130613. Epub 2013 Nov 1.


Dominant suppression of inflammation by glycan-hydrolyzed IgG.

Nandakumar KS, Collin M, Happonen KE, Croxford AM, Lundström SL, Zubarev RA, Rowley MJ, Blom AM, Holmdahl R.

Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10252-7. doi: 10.1073/pnas.1301480110. Epub 2013 May 13. Retraction in: Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):15851.


Interactions of the complement system with molecules of extracellular matrix: relevance for joint diseases.

Happonen KE, Heinegård D, Saxne T, Blom AM.

Immunobiology. 2012 Nov;217(11):1088-96. doi: 10.1016/j.imbio.2012.07.013. Review.


PRELP protein inhibits the formation of the complement membrane attack complex.

Happonen KE, Fürst CM, Saxne T, Heinegård D, Blom AM.

J Biol Chem. 2012 Mar 9;287(11):8092-100. doi: 10.1074/jbc.M111.291476. Epub 2012 Jan 20. Erratum in: J Biol Chem. 2012 Jun 1;287(23):19338.


Serum COMP-C3b complexes in rheumatic diseases and relation to anti-TNF-α treatment.

Happonen KE, Saxne T, Geborek P, Andersson M, Bengtsson AA, Hesselstrand R, Heinegård D, Blom AM.

Arthritis Res Ther. 2012 Jan 20;14(1):R15. doi: 10.1186/ar3694.


Serglycin inhibits the classical and lectin pathways of complement via its glycosaminoglycan chains: implications for multiple myeloma.

Skliris A, Happonen KE, Terpos E, Labropoulou V, Børset M, Heinegård D, Blom AM, Theocharis AD.

Eur J Immunol. 2011 Feb;41(2):437-49. doi: 10.1002/eji.201040429. Epub 2010 Dec 30.


Regulation of complement by cartilage oligomeric matrix protein allows for a novel molecular diagnostic principle in rheumatoid arthritis.

Happonen KE, Saxne T, Aspberg A, Mörgelin M, Heinegård D, Blom AM.

Arthritis Rheum. 2010 Dec;62(12):3574-83. doi: 10.1002/art.27720.


Complement inhibitor C4b-binding protein interacts directly with small glycoproteins of the extracellular matrix.

Happonen KE, Sjöberg AP, Mörgelin M, Heinegård D, Blom AM.

J Immunol. 2009 Feb 1;182(3):1518-25.

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