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Items: 39

1.

Advances in Membrane Trafficking and Endosomal Signaling of G Protein-Coupled Receptors.

Hanyaloglu AC.

Int Rev Cell Mol Biol. 2018;339:93-131. doi: 10.1016/bs.ircmb.2018.03.001. Epub 2018 Apr 30.

PMID:
29776606
2.

Targeting GLP-1 receptor trafficking to improve agonist efficacy.

Jones B, Buenaventura T, Kanda N, Chabosseau P, Owen BM, Scott R, Goldin R, Angkathunyakul N, Corrêa IR Jr, Bosco D, Johnson PR, Piemonti L, Marchetti P, Shapiro AMJ, Cochran BJ, Hanyaloglu AC, Inoue A, Tan T, Rutter GA, Tomas A, Bloom SR.

Nat Commun. 2018 Apr 23;9(1):1602. doi: 10.1038/s41467-018-03941-2.

3.

Structural Lipids Enable the Formation of Functional Oligomers of the Eukaryotic Purine Symporter UapA.

Pyle E, Kalli AC, Amillis S, Hall Z, Lau AM, Hanyaloglu AC, Diallinas G, Byrne B, Politis A.

Cell Chem Biol. 2018 Apr 10. pii: S2451-9456(18)30113-2. doi: 10.1016/j.chembiol.2018.03.011. [Epub ahead of print]

4.

A calcium-sensing receptor mutation causing hypocalcemia disrupts a transmembrane salt bridge to activate β-arrestin-biased signaling.

Gorvin CM, Babinsky VN, Malinauskas T, Nissen PH, Schou AJ, Hanyaloglu AC, Siebold C, Jones EY, Hannan FM, Thakker RV.

Sci Signal. 2018 Feb 20;11(518). pii: eaan3714. doi: 10.1126/scisignal.aan3714.

5.

AP2? Mutations Impair Calcium-Sensing Receptor Trafficking and Signaling, and Show an Endosomal Pathway to Spatially Direct G-Protein Selectivity.

Gorvin CM, Rogers A, Hastoy B, Tarasov AI, Frost M, Sposini S, Inoue A, Whyte MP, Rorsman P, Hanyaloglu AC, Breitwieser GE, Thakker RV.

Cell Rep. 2018 Jan 23;22(4):1054-1066. doi: 10.1016/j.celrep.2017.12.089. Epub 2018 Jan 28.

6.

Temporal reprogramming of calcium signalling via crosstalk of gonadotrophin receptors that associate as functionally asymmetric heteromers.

Jonas KC, Chen S, Virta M, Mora J, Franks S, Huhtaniemi I, Hanyaloglu AC.

Sci Rep. 2018 Feb 2;8(1):2239. doi: 10.1038/s41598-018-20722-5.

7.

The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat.

Schilperoort M, van Dam AD, Hoeke G, Shabalina IG, Okolo A, Hanyaloglu AC, Dib LH, Mol IM, Caengprasath N, Chan YW, Damak S, Miller AR, Coskun T, Shimpukade B, Ulven T, Kooijman S, Rensen PC, Christian M.

EMBO Mol Med. 2018 Mar;10(3). pii: e8047. doi: 10.15252/emmm.201708047.

8.

Integration of GPCR Signaling and Sorting from Very Early Endosomes via Opposing APPL1 Mechanisms.

Sposini S, Jean-Alphonse FG, Ayoub MA, Oqua A, West C, Lavery S, Brosens JJ, Reiter E, Hanyaloglu AC.

Cell Rep. 2017 Dec 5;21(10):2855-2867. doi: 10.1016/j.celrep.2017.11.023.

9.

The direct and indirect effects of kisspeptin-54 on granulosa lutein cell function.

Owens LA, Abbara A, Lerner A, O'floinn S, Christopoulos G, Khanjani S, Islam R, Hardy K, Hanyaloglu AC, Lavery SA, Dhillo WS, Franks S.

Hum Reprod. 2018 Feb 1;33(2):292-302. doi: 10.1093/humrep/dex357.

PMID:
29206944
10.

Pleiotropic GPCR signaling in health and disease.

Hanyaloglu AC, Grammatopoulos DK.

Mol Cell Endocrinol. 2017 Jul 5;449:1-2. doi: 10.1016/j.mce.2017.05.013. No abstract available.

11.

Spatial encryption of G protein-coupled receptor signaling in endosomes; Mechanisms and applications.

Sposini S, Hanyaloglu AC.

Biochem Pharmacol. 2017 Nov 1;143:1-9. doi: 10.1016/j.bcp.2017.04.028. Epub 2017 Apr 27. Review.

12.

Impact of G protein-coupled receptor heteromers in endocrine systems.

Jonas KC, Hanyaloglu AC.

Mol Cell Endocrinol. 2017 Jul 5;449:21-27. doi: 10.1016/j.mce.2017.01.030. Epub 2017 Jan 20. Review.

13.

Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders.

Babinsky VN, Hannan FM, Gorvin CM, Howles SA, Nesbit MA, Rust N, Hanyaloglu AC, Hu J, Spiegel AM, Thakker RV.

J Biol Chem. 2016 May 13;291(20):10876-85. doi: 10.1074/jbc.M115.696401. Epub 2016 Mar 18.

14.

Single-molecule resolution of G protein-coupled receptor (GPCR) complexes.

Jonas KC, Huhtaniemi I, Hanyaloglu AC.

Methods Cell Biol. 2016;132:55-72. doi: 10.1016/bs.mcb.2015.11.005. Epub 2015 Dec 24. Review.

PMID:
26928539
15.

The oxytocin receptor antagonist, Atosiban, activates pro-inflammatory pathways in human amnion via G(αi) signalling.

Kim SH, MacIntyre DA, Hanyaloglu AC, Blanks AM, Thornton S, Bennett PR, Terzidou V.

Mol Cell Endocrinol. 2016 Jan 15;420:11-23. doi: 10.1016/j.mce.2015.11.012. Epub 2015 Nov 14.

16.

Minireview: Spatial Programming of G Protein-Coupled Receptor Activity: Decoding Signaling in Health and Disease.

West C, Hanyaloglu AC.

Mol Endocrinol. 2015 Aug;29(8):1095-106. doi: 10.1210/ME.2015-1065. Epub 2015 Jun 29. Review.

17.

Single molecule analysis of functionally asymmetric G protein-coupled receptor (GPCR) oligomers reveals diverse spatial and structural assemblies.

Jonas KC, Fanelli F, Huhtaniemi IT, Hanyaloglu AC.

J Biol Chem. 2015 Feb 13;290(7):3875-92. doi: 10.1074/jbc.M114.622498. Epub 2014 Dec 16.

18.

Identification of transmembrane domains that regulate spatial arrangements and activity of prokineticin receptor 2 dimers.

Sposini S, Caltabiano G, Hanyaloglu AC, Miele R.

Mol Cell Endocrinol. 2015 Jan 5;399:362-72. doi: 10.1016/j.mce.2014.10.024. Epub 2014 Nov 6.

19.

Arachidonic acid-dependent gene regulation during preadipocyte differentiation controls adipocyte potential.

Nikolopoulou E, Papacleovoulou G, Jean-Alphonse F, Grimaldi G, Parker MG, Hanyaloglu AC, Christian M.

J Lipid Res. 2014 Dec;55(12):2479-90. doi: 10.1194/jlr.M049551. Epub 2014 Oct 16.

20.

The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via free fatty acid receptor 2 in rodents.

Psichas A, Sleeth ML, Murphy KG, Brooks L, Bewick GA, Hanyaloglu AC, Ghatei MA, Bloom SR, Frost G.

Int J Obes (Lond). 2015 Mar;39(3):424-9. doi: 10.1038/ijo.2014.153. Epub 2014 Aug 11.

21.

Spatially restricted G protein-coupled receptor activity via divergent endocytic compartments.

Jean-Alphonse F, Bowersox S, Chen S, Beard G, Puthenveedu MA, Hanyaloglu AC.

J Biol Chem. 2014 Feb 14;289(7):3960-77. doi: 10.1074/jbc.M113.526350. Epub 2013 Dec 27.

22.

EP2 receptor activates dual G protein signaling pathways that mediate contrasting proinflammatory and relaxatory responses in term pregnant human myometrium.

Kandola MK, Sykes L, Lee YS, Johnson MR, Hanyaloglu AC, Bennett PR.

Endocrinology. 2014 Feb;155(2):605-17. doi: 10.1210/en.2013-1761. Epub 2013 Nov 21.

PMID:
24265450
23.

G protein-coupled receptor transactivation: from molecules to mice.

Jonas KC, Rivero-Müller A, Huhtaniemi IT, Hanyaloglu AC.

Methods Cell Biol. 2013;117:433-50. doi: 10.1016/B978-0-12-408143-7.00023-2.

PMID:
24143991
24.

Di/oligomerization of GPCRs-mechanisms and functional significance.

Rivero-Müller A, Jonas KC, Hanyaloglu AC, Huhtaniemi I.

Prog Mol Biol Transl Sci. 2013;117:163-85. doi: 10.1016/B978-0-12-386931-9.00007-6. Review.

PMID:
23663969
25.

The roles of prostaglandin EP 1 and 3 receptors in the control of human myometrial contractility.

Arulkumaran S, Kandola MK, Hoffman B, Hanyaloglu AC, Johnson MR, Bennett PR.

J Clin Endocrinol Metab. 2012 Feb;97(2):489-98. doi: 10.1210/jc.2011-1991. Epub 2011 Dec 7.

PMID:
22162473
26.

NADPH oxidase-derived reactive oxygen species mediate decidualization of human endometrial stromal cells in response to cyclic AMP signaling.

Al-Sabbagh M, Fusi L, Higham J, Lee Y, Lei K, Hanyaloglu AC, Lam EW, Christian M, Brosens JJ.

Endocrinology. 2011 Feb;152(2):730-40. doi: 10.1210/en.2010-0899. Epub 2010 Dec 15.

27.

Regulation of GPCR signal networks via membrane trafficking.

Jean-Alphonse F, Hanyaloglu AC.

Mol Cell Endocrinol. 2011 Jan 15;331(2):205-14. doi: 10.1016/j.mce.2010.07.010. Epub 2010 Jul 21. Review.

PMID:
20654691
28.

Rescue of defective G protein-coupled receptor function in vivo by intermolecular cooperation.

Rivero-Müller A, Chou YY, Ji I, Lajic S, Hanyaloglu AC, Jonas K, Rahman N, Ji TH, Huhtaniemi I.

Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):2319-24. doi: 10.1073/pnas.0906695106. Epub 2010 Jan 11.

29.

The ubiquitin-like protein PLIC-2 is a negative regulator of G protein-coupled receptor endocytosis.

N'Diaye EN, Hanyaloglu AC, Kajihara KK, Puthenveedu MA, Wu P, von Zastrow M, Brown EJ.

Mol Biol Cell. 2008 Mar;19(3):1252-60. doi: 10.1091/mbc.E07-08-0775. Epub 2008 Jan 16.

30.

Regulation of GPCRs by endocytic membrane trafficking and its potential implications.

Hanyaloglu AC, von Zastrow M.

Annu Rev Pharmacol Toxicol. 2008;48:537-68. doi: 10.1146/annurev.pharmtox.48.113006.094830. Review.

PMID:
18184106
31.

A novel sorting sequence in the beta2-adrenergic receptor switches recycling from default to the Hrs-dependent mechanism.

Hanyaloglu AC, von Zastrow M.

J Biol Chem. 2007 Feb 2;282(5):3095-104. Epub 2006 Nov 30.

32.

Essential role of Hrs in a recycling mechanism mediating functional resensitization of cell signaling.

Hanyaloglu AC, McCullagh E, von Zastrow M.

EMBO J. 2005 Jul 6;24(13):2265-83. Epub 2005 Jun 9.

33.

Functional deletion of the calcium-sensing receptor in a case of neonatal severe hyperparathyroidism.

Ward BK, Magno AL, Davis EA, Hanyaloglu AC, Stuckey BG, Burrows M, Eidne KA, Charles AK, Ratajczak T.

J Clin Endocrinol Metab. 2004 Aug;89(8):3721-30.

PMID:
15292296
34.

Gonadotropin-releasing hormone receptor-mediated growth suppression of immortalized LbetaT2 gonadotrope and stable HEK293 cell lines.

Miles LE, Hanyaloglu AC, Dromey JR, Pfleger KD, Eidne KA.

Endocrinology. 2004 Jan;145(1):194-204. Epub 2003 Oct 9.

PMID:
14551223
35.

Applications of novel resonance energy transfer techniques to study dynamic hormone receptor interactions in living cells.

Eidne KA, Kroeger KM, Hanyaloglu AC.

Trends Endocrinol Metab. 2002 Dec;13(10):415-21. Review.

PMID:
12431837
36.

Homo- and hetero-oligomerization of thyrotropin-releasing hormone (TRH) receptor subtypes. Differential regulation of beta-arrestins 1 and 2.

Hanyaloglu AC, Seeber RM, Kohout TA, Lefkowitz RJ, Eidne KA.

J Biol Chem. 2002 Dec 27;277(52):50422-30. Epub 2002 Oct 21.

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