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J Clin Microbiol. 2016 Jan;54(1):175-7. doi: 10.1128/JCM.02405-15. Epub 2015 Oct 21.

Evaluation of the Lyra Direct Strep Assay To Detect Group A Streptococcus and Group C and G Beta-Hemolytic Streptococcus from Pharyngeal Specimens.

Author information

1
Department of Pathology & Laboratory Medicine, Beaumont Health, Royal Oak, Michigan, USA Oakland University William Beaumont School of Medicine, Rochester, Michigan, USA bobby.boyanton@beaumont.edu.
2
Department of Pathology & Laboratory Medicine, Beaumont Health, Royal Oak, Michigan, USA.
3
Department of Pathology & Laboratory Medicine, Beaumont Health, Royal Oak, Michigan, USA Oakland University William Beaumont School of Medicine, Rochester, Michigan, USA.

Abstract

The Lyra Direct strep assay was compared to culture for its ability to detect Streptococcus group A and β-hemolytic groups C/G using rapid antigen-negative pharyngeal specimens (n = 161). The Lyra assay correctly detected all β-hemolytic streptococci (group A, n = 19; group C/G, n = 5). In batch mode, the Lyra assay reduced intralaboratory turnaround time by 60% (18.1 h versus 45.0 h) but increased hands-on time by 96% (3 min 16 s versus 1 min 40 s per specimen).

PMID:
26491174
PMCID:
PMC4702764
DOI:
10.1128/JCM.02405-15
[Indexed for MEDLINE]
Free PMC Article

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