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Items: 1 to 50 of 184

1.

Manufacturing considerations for producing and assessing decellularized extracellular matrix hydrogels.

Hernandez MJ, Yakutis GE, Zelus EI, Hill RC, Dzieciatkowska M, Hansen KC, Christman KL.

Methods. 2019 Sep 20. pii: S1046-2023(18)30438-9. doi: 10.1016/j.ymeth.2019.09.015. [Epub ahead of print]

PMID:
31546012
2.

The metabolic time line of pancreatic cancer: Opportunities to improve early detection of adenocarcinoma.

Moore HB, Culp-Hill R, Reisz JA, Lawson PJ, Sauaia A, Schulick RD, Del Chiaro M, Nydam TL, Moore EE, Hansen KC, D'Alessandro A.

Am J Surg. 2019 Aug 27. pii: S0002-9610(19)30382-4. doi: 10.1016/j.amjsurg.2019.08.015. [Epub ahead of print]

PMID:
31514959
3.

A unified mechanism for intron and exon definition and back-splicing.

Li X, Liu S, Zhang L, Issaian A, Hill RC, Espinosa S, Shi S, Cui Y, Kappel K, Das R, Hansen KC, Zhou ZH, Zhao R.

Nature. 2019 Sep;573(7774):375-380. doi: 10.1038/s41586-019-1523-6. Epub 2019 Sep 4.

PMID:
31485080
4.

Streptococcus pneumoniae G5 domains bind different ligands.

Paukovich N, Redzic JS, Chi YC, Rahkola JT, Issaian A, Blue A, Hansen KC, Janoff EN, Eisenmesser EZ.

Protein Sci. 2019 Oct;28(10):1797-1805. doi: 10.1002/pro.3693. Epub 2019 Aug 9.

PMID:
31390088
5.

Parabiosis Incompletely Reverses Aging-Induced Metabolic Changes and Oxidant Stress in Mouse Red Blood Cells.

Morrison EJ, Champagne DP, Dzieciatkowska M, Nemkov T, Zimring JC, Hansen KC, Guan F, Huffman DM, Santambrogio L, D'Alessandro A.

Nutrients. 2019 Jun 14;11(6). pii: E1337. doi: 10.3390/nu11061337.

6.

Protect, repair, destroy or sacrifice: a role of oxidative stress biology in inter-donor variability of blood storage?

D'Alessandro A, Hansen KC, Eisenmesser EZ, Zimring JC.

Blood Transfus. 2019 Jul;17(4):281-288. doi: 10.2450/2019.0072-19. Epub 2019 Jun 6. Review.

7.

Prospective assessment of fibrinolysis in morbid obesity: tissue plasminogen activator resistance improves after bariatric surgery.

Samuels J, Lawson PJ, Morton AP, Moore HB, Hansen KC, Sauaia A, Schoen JA.

Surg Obes Relat Dis. 2019 Jul;15(7):1153-1159. doi: 10.1016/j.soard.2019.03.048. Epub 2019 Apr 10.

PMID:
31128997
8.

High-Throughput Metabolomics: Isocratic and Gradient Mass Spectrometry-Based Methods.

Nemkov T, Reisz JA, Gehrke S, Hansen KC, D'Alessandro A.

Methods Mol Biol. 2019;1978:13-26. doi: 10.1007/978-1-4939-9236-2_2.

PMID:
31119654
9.

Mass spectrometry-based molecular mapping of native FXIIIa cross-links in insoluble fibrin clots.

Schmitt LR, Henderson R, Barrett A, Darula Z, Issaian A, D'Alessandro A, Clendenen N, Hansen KC.

J Biol Chem. 2019 May 31;294(22):8773-8778. doi: 10.1074/jbc.AC119.007981. Epub 2019 Apr 26.

PMID:
31028172
10.

Pancreatic Tumor Microenvironment Modulation by EphB4-ephrinB2 Inhibition and Radiation Combination.

Lennon S, Oweida A, Milner D, Phan AV, Bhatia S, Van Court B, Darragh L, Mueller AC, Raben D, Martínez-Torrecuadrada JL, Pitts TM, Somerset H, Jordan KR, Hansen KC, Williams J, Messersmith WA, Schulick RD, Owens P, Goodman KA, Karam SD.

Clin Cancer Res. 2019 Jun 1;25(11):3352-3365. doi: 10.1158/1078-0432.CCR-18-2811. Epub 2019 Apr 3.

PMID:
30944125
11.

Targeting Glutamine Metabolism and Redox State for Leukemia Therapy.

Gregory MA, Nemkov T, Park HJ, Zaberezhnyy V, Gehrke S, Adane B, Jordan CT, Hansen KC, D'Alessandro A, DeGregori J.

Clin Cancer Res. 2019 Jul 1;25(13):4079-4090. doi: 10.1158/1078-0432.CCR-18-3223. Epub 2019 Apr 2.

PMID:
30940653
12.

Does Tranexamic Acid Improve Clot Strength in Severely Injured Patients Who Have Elevated Fibrin Degradation Products and Low Fibrinolytic Activity, Measured by Thrombelastography?

Moore HB, Moore EE, Chapman MP, Hansen KC, Cohen MJ, Pieracci FM, Chandler J, Sauaia A.

J Am Coll Surg. 2019 Jul;229(1):92-101. doi: 10.1016/j.jamcollsurg.2019.03.015. Epub 2019 Mar 29.

PMID:
30936005
13.

Functional Insights from the Proteomic Inventory of Ovine Forestomach Matrix.

Dempsey SG, Miller CH, Hill RC, Hansen KC, May BCH.

J Proteome Res. 2019 Apr 5;18(4):1657-1668. doi: 10.1021/acs.jproteome.8b00908. Epub 2019 Mar 25.

PMID:
30879303
14.

Red Blood Cell Metabolic Responses to Torpor and Arousal in the Hibernator Arctic Ground Squirrel.

Gehrke S, Rice S, Stefanoni D, Wilkerson RB, Nemkov T, Reisz JA, Hansen KC, Lucas A, Cabrales P, Drew K, D'Alessandro A.

J Proteome Res. 2019 Apr 5;18(4):1827-1841. doi: 10.1021/acs.jproteome.9b00018. Epub 2019 Feb 28.

PMID:
30793910
15.

Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy.

Carlson P, Dasgupta A, Grzelak CA, Kim J, Barrett A, Coleman IM, Shor RE, Goddard ET, Dai J, Schweitzer EM, Lim AR, Crist SB, Cheresh DA, Nelson PS, Hansen KC, Ghajar CM.

Nat Cell Biol. 2019 Feb;21(2):238-250. doi: 10.1038/s41556-018-0267-0. Epub 2019 Jan 21.

PMID:
30664790
16.

Evaluation of different decellularization protocols on the generation of pancreas-derived hydrogels.

Gaetani R, Aouad S, Demaddalena LL, Straessle H, Dzieciatkowska M, Wortham M, Bender HR, Nguyen-Ngoc KV, Schmid-Schoenbein GW, George SC, Hughes CCW, Sander M, Hansen KC, Christman KL.

Tissue Eng Part C Methods. 2018 Nov 6. doi: 10.1089/ten.TEC.2018.0180. [Epub ahead of print]

PMID:
30398401
17.

Methylation of protein aspartates and deamidated asparagines as a function of blood bank storage and oxidative stress in human red blood cells.

Reisz JA, Nemkov T, Dzieciatkowska M, Culp-Hill R, Stefanoni D, Hill RC, Yoshida T, Dunham A, Kanias T, Dumont LJ, Busch M, Eisenmesser EZ, Zimring JC, Hansen KC, D'Alessandro A.

Transfusion. 2018 Dec;58(12):2978-2991. doi: 10.1111/trf.14936. Epub 2018 Oct 12.

PMID:
30312994
18.

A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma.

Barnes JM, Kaushik S, Bainer RO, Sa JK, Woods EC, Kai F, Przybyla L, Lee M, Lee HW, Tung JC, Maller O, Barrett AS, Lu KV, Lakins JN, Hansen KC, Obernier K, Alvarez-Buylla A, Bergers G, Phillips JJ, Nam DH, Bertozzi CR, Weaver VM.

Nat Cell Biol. 2018 Oct;20(10):1203-1214. doi: 10.1038/s41556-018-0183-3. Epub 2018 Sep 10.

PMID:
30202050
19.

SILAC-MS Profiling of Reconstituted Human Chromatin Platforms for the Study of Transcription and RNA Regulation.

Balas MM, Porman AM, Hansen KC, Johnson AM.

J Proteome Res. 2018 Oct 5;17(10):3475-3484. doi: 10.1021/acs.jproteome.8b00395. Epub 2018 Sep 20.

20.

A comparison of different methods of red blood cell leukoreduction and additive solutions on the accumulation of neutrophil-priming activity during storage.

Loi MM, Kelher M, Dzieciatkowska M, Hansen KC, Banerjee A, West FB, Stanley C, Briel M, Silliman CC.

Transfusion. 2018 Aug;58(8):2003-2012. doi: 10.1111/trf.14788. Epub 2018 Sep 1.

21.

Targeted matrisome analysis identifies thrombospondin-2 and tenascin-C in aligned collagen stroma from invasive breast carcinoma.

Tomko LA, Hill RC, Barrett A, Szulczewski JM, Conklin MW, Eliceiri KW, Keely PJ, Hansen KC, Ponik SM.

Sci Rep. 2018 Aug 28;8(1):12941. doi: 10.1038/s41598-018-31126-w.

22.

Quantitative Profiling of the Lymph Node Clearance Capacity.

Clement CC, Wang W, Dzieciatkowska M, Cortese M, Hansen KC, Becerra A, Thangaswamy S, Nizamutdinova I, Moon JY, Stern LJ, Gashev AA, Zawieja D, Santambrogio L.

Sci Rep. 2018 Jul 26;8(1):11253. doi: 10.1038/s41598-018-29614-0.

23.

Krypton isotopes and noble gas abundances in the coma of comet 67P/Churyumov-Gerasimenko.

Rubin M, Altwegg K, Balsiger H, Bar-Nun A, Berthelier JJ, Briois C, Calmonte U, Combi M, De Keyser J, Fiethe B, Fuselier SA, Gasc S, Gombosi TI, Hansen KC, Kopp E, Korth A, Laufer D, Le Roy L, Mall U, Marty B, Mousis O, Owen T, Rème H, Sémon T, Tzou CY, Waite JH, Wurz P.

Sci Adv. 2018 Jul 4;4(7):eaar6297. doi: 10.1126/sciadv.aar6297. eCollection 2018 Jul.

24.

Glycogen synthase kinase-3 (GSK-3) activity regulates mRNA methylation in mouse embryonic stem cells.

Faulds KJ, Egelston JN, Sedivy LJ, Mitchell MK, Garimella S, Kozlowski H, D'Alessandro A, Hansen KC, Balsbaugh JL, Phiel CJ.

J Biol Chem. 2018 Jul 6;293(27):10731-10743. doi: 10.1074/jbc.RA117.001298. Epub 2018 May 18.

25.

Author Correction: CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing.

Li X, Liu S, Jiang J, Zhang L, Espinosa S, Hill RC, Hansen KC, Zhou ZH, Zhao R.

Nat Commun. 2018 Apr 11;9(1):1495. doi: 10.1038/s41467-018-03708-9.

26.

When nature's robots go rogue: exploring protein homeostasis dysfunction and the implications for understanding human aging disease pathologies.

Reisz JA, Barrett AS, Nemkov T, Hansen KC, D'Alessandro A.

Expert Rev Proteomics. 2018 Apr;15(4):293-309. doi: 10.1080/14789450.2018.1453362. Epub 2018 Mar 21. Review.

27.

Extracellular matrix in lung development, homeostasis and disease.

Zhou Y, Horowitz JC, Naba A, Ambalavanan N, Atabai K, Balestrini J, Bitterman PB, Corley RA, Ding BS, Engler AJ, Hansen KC, Hagood JS, Kheradmand F, Lin QS, Neptune E, Niklason L, Ortiz LA, Parks WC, Tschumperlin DJ, White ES, Chapman HA, Thannickal VJ.

Matrix Biol. 2018 Nov;73:77-104. doi: 10.1016/j.matbio.2018.03.005. Epub 2018 Mar 8. Review.

PMID:
29524630
28.

Correction: An autonomous metabolic role for Spen.

Hazegh KE, Nemkov T, D'Alessandro A, Diller JD, Monks J, McManaman JL, Jones KL, Hansen KC, Reis T.

PLoS Genet. 2018 Mar 6;14(3):e1007266. doi: 10.1371/journal.pgen.1007266. eCollection 2018 Mar.

29.

Red blood cell metabolism in Down syndrome: hints on metabolic derangements in aging.

Culp-Hill R, Zheng C, Reisz JA, Smith K, Rachubinski A, Nemkov T, Butcher E, Granrath R, Hansen KC, Espinosa JM, D'Alessandro A.

Blood Adv. 2017 Dec 21;1(27):2776-2780. doi: 10.1182/bloodadvances.2017011957. eCollection 2017 Dec 26.

30.

Red blood cells in hemorrhagic shock: a critical role for glutaminolysis in fueling alanine transamination in rats.

Reisz JA, Slaughter AL, Culp-Hill R, Moore EE, Silliman CC, Fragoso M, Peltz ED, Hansen KC, Banerjee A, D'Alessandro A.

Blood Adv. 2017 Jul 14;1(17):1296-1305. doi: 10.1182/bloodadvances.2017007187. eCollection 2017 Jul 25.

31.

Fibrinolysis shutdown is associated with a fivefold increase in mortality in trauma patients lacking hypersensitivity to tissue plasminogen activator.

Moore HB, Moore EE, Huebner BR, Dzieciatkowska M, Stettler GR, Nunns GR, Lawson PJ, Ghasabyan A, Chandler J, Banerjee A, Silliman C, Sauaia A, Hansen KC.

J Trauma Acute Care Surg. 2017 Dec;83(6):1014-1022. doi: 10.1097/TA.0000000000001718.

32.

Structure of the yeast spliceosomal postcatalytic P complex.

Liu S, Li X, Zhang L, Jiang J, Hill RC, Cui Y, Hansen KC, Zhou ZH, Zhao R.

Science. 2017 Dec 8;358(6368):1278-1283. doi: 10.1126/science.aar3462. Epub 2017 Nov 16.

33.

Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease.

Sun K, D'Alessandro A, Ahmed MH, Zhang Y, Song A, Ko TP, Nemkov T, Reisz JA, Wu H, Adebiyi M, Peng Z, Gong J, Liu H, Huang A, Wen YE, Wen AQ, Berka V, Bogdanov MV, Abdulmalik O, Han L, Tsai AL, Idowu M, Juneja HS, Kellems RE, Dowhan W, Hansen KC, Safo MK, Xia Y.

Sci Rep. 2017 Nov 10;7(1):15281. doi: 10.1038/s41598-017-13667-8.

34.

All animals are equal but some animals are more equal than others: Plasma lactate and succinate in hemorrhagic shock-A comparison in rodents, swine, nonhuman primates, and injured patients.

Reisz JA, Wither MJ, Moore EE, Slaughter AL, Moore HB, Ghasabyan A, Chandler J, Schaub LJ, Fragoso M, Nunns G, Silliman CC, Hansen KC, Banerjee A, Sheppard FR, D'Alessandro A.

J Trauma Acute Care Surg. 2018 Mar;84(3):537-541. doi: 10.1097/TA.0000000000001721.

35.

Metabolism of Citrate and Other Carboxylic Acids in Erythrocytes As a Function of Oxygen Saturation and Refrigerated Storage.

Nemkov T, Sun K, Reisz JA, Yoshida T, Dunham A, Wen EY, Wen AQ, Roach RC, Hansen KC, Xia Y, D'Alessandro A.

Front Med (Lausanne). 2017 Oct 17;4:175. doi: 10.3389/fmed.2017.00175. eCollection 2017.

36.

Hypoxia modulates the purine salvage pathway and decreases red blood cell and supernatant levels of hypoxanthine during refrigerated storage.

Nemkov T, Sun K, Reisz JA, Song A, Yoshida T, Dunham A, Wither MJ, Francis RO, Roach RC, Dzieciatkowska M, Rogers SC, Doctor A, Kriebardis A, Antonelou M, Papassideri I, Young CT, Thomas TA, Hansen KC, Spitalnik SL, Xia Y, Zimring JC, Hod EA, D'Alessandro A.

Haematologica. 2018 Feb;103(2):361-372. doi: 10.3324/haematol.2017.178608. Epub 2017 Oct 27.

37.

CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing.

Li X, Liu S, Jiang J, Zhang L, Espinosa S, Hill RC, Hansen KC, Zhou ZH, Zhao R.

Nat Commun. 2017 Oct 19;8(1):1035. doi: 10.1038/s41467-017-01241-9. Erratum in: Nat Commun. 2018 Apr 11;9(1):1495.

38.

Hydroxylamine Chemical Digestion for Insoluble Extracellular Matrix Characterization.

Barrett AS, Wither MJ, Hill RC, Dzieciatkowska M, D'Alessandro A, Reisz JA, Hansen KC.

J Proteome Res. 2017 Nov 3;16(11):4177-4184. doi: 10.1021/acs.jproteome.7b00527.

39.

Glutaminase inhibition improves FLT3 inhibitor therapy for acute myeloid leukemia.

Gregory MA, Nemkov T, Reisz JA, Zaberezhnyy V, Hansen KC, D'Alessandro A, DeGregori J.

Exp Hematol. 2018 Feb;58:52-58. doi: 10.1016/j.exphem.2017.09.007. Epub 2017 Sep 22.

40.

Investigation of the effects of storage and freezing on mixes of heavy-labeled metabolite and amino acid standards.

Culp-Hill R, Reisz JA, Hansen KC, D'Alessandro A.

Rapid Commun Mass Spectrom. 2017 Dec 15;31(23):2030-2034. doi: 10.1002/rcm.7989.

41.

Folate dietary insufficiency and folic acid supplementation similarly impair metabolism and compromise hematopoiesis.

Henry CJ, Nemkov T, Casás-Selves M, Bilousova G, Zaberezhnyy V, Higa KC, Serkova NJ, Hansen KC, D'Alessandro A, DeGregori J.

Haematologica. 2017 Dec;102(12):1985-1994. doi: 10.3324/haematol.2017.171074. Epub 2017 Sep 7.

42.

The Metabolopathy of Tissue Injury, Hemorrhagic Shock, and Resuscitation in a Rat Model.

Slaughter AL, Nunns GR, D'Alessandro A, Banerjee A, Hansen KC, Moore EE, Silliman CC, Nemkov T, Moore HB, Fragoso M, Leasia K, Peltz ED.

Shock. 2018 May;49(5):580-590. doi: 10.1097/SHK.0000000000000948.

43.

Blood and Plasma Proteomics: Targeted Quantitation and Posttranslational Redox Modifications.

Reisz JA, Chessler KM, Dzieciatkowska M, D'Alessandro A, Hansen KC.

Methods Mol Biol. 2017;1619:353-371. doi: 10.1007/978-1-4939-7057-5_24.

PMID:
28674896
44.

Prevalence of antimicrobial resistance and the cfiA resistance gene in Danish Bacteroides fragilis group isolates since 1973.

Ferløv-Schwensen SA, Sydenham TV, Hansen KCM, Hoegh SV, Justesen US.

Int J Antimicrob Agents. 2017 Oct;50(4):552-556. doi: 10.1016/j.ijantimicag.2017.05.007. Epub 2017 Jun 27.

PMID:
28666749
45.

An autonomous metabolic role for Spen.

Hazegh KE, Nemkov T, D'Alessandro A, Diller JD, Monks J, McManaman JL, Jones KL, Hansen KC, Reis T.

PLoS Genet. 2017 Jun 22;13(6):e1006859. doi: 10.1371/journal.pgen.1006859. eCollection 2017 Jun. Erratum in: PLoS Genet. 2018 Mar 6;14 (3):e1007266.

46.

Xenon isotopes in 67P/Churyumov-Gerasimenko show that comets contributed to Earth's atmosphere.

Marty B, Altwegg K, Balsiger H, Bar-Nun A, Bekaert DV, Berthelier JJ, Bieler A, Briois C, Calmonte U, Combi M, De Keyser J, Fiethe B, Fuselier SA, Gasc S, Gombosi TI, Hansen KC, Hässig M, Jäckel A, Kopp E, Korth A, Le Roy L, Mall U, Mousis O, Owen T, Rème H, Rubin M, Sémon T, Tzou CY, Waite JH, Wurz P.

Science. 2017 Jun 9;356(6342):1069-1072. doi: 10.1126/science.aal3496.

PMID:
28596364
47.

Plasma succinate is a predictor of mortality in critically injured patients.

DʼAlessandro A, Moore HB, Moore EE, Reisz JA, Wither MJ, Ghasasbyan A, Chandler J, Silliman CC, Hansen KC, Banerjee A.

J Trauma Acute Care Surg. 2017 Sep;83(3):491-495. doi: 10.1097/TA.0000000000001565.

48.

Characterization of rapid extraction protocols for high-throughput metabolomics.

Gehrke S, Reisz JA, Nemkov T, Hansen KC, D'Alessandro A.

Rapid Commun Mass Spectrom. 2017 Sep 15;31(17):1445-1452. doi: 10.1002/rcm.7916.

49.

Erythrocyte purinergic signaling components underlie hypoxia adaptation.

Sun K, Liu H, Song A, Manalo JM, D'Alessandro A, Hansen KC, Kellems RE, Eltzschig HK, Blackburn MR, Roach RC, Xia Y.

J Appl Physiol (1985). 2017 Oct 1;123(4):951-956. doi: 10.1152/japplphysiol.00155.2017. Epub 2017 Jun 1. Review.

50.

Antimicrobial resistance in the Bacteroides fragilis group in faecal samples from patients receiving broad-spectrum antibiotics.

Hansen KCM, Schwensen SAF, Henriksen DP, Justesen US, Sydenham TV.

Anaerobe. 2017 Oct;47:79-85. doi: 10.1016/j.anaerobe.2017.04.013. Epub 2017 Apr 23.

PMID:
28445776

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