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Items: 1 to 50 of 170

1.

Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy.

Carlson P, Dasgupta A, Grzelak CA, Kim J, Barrett A, Coleman IM, Shor RE, Goddard ET, Dai J, Schweitzer EM, Lim AR, Crist SB, Cheresh DA, Nelson PS, Hansen KC, Ghajar CM.

Nat Cell Biol. 2019 Feb;21(2):238-250. doi: 10.1038/s41556-018-0267-0. Epub 2019 Jan 21.

PMID:
30664790
2.

Evaluation of different decellularization protocols on the generation of pancreas-derived hydrogels.

Gaetani R, Aouad S, Demaddalena LL, Straessle H, Dzieciatkowska M, Wortham M, Bender HR, Nguyen-Ngoc KV, Schmid-Schoenbein GW, George SC, Hughes CCW, Sander M, Hansen KC, Christman KL.

Tissue Eng Part C Methods. 2018 Nov 6. doi: 10.1089/ten.TEC.2018.0180. [Epub ahead of print]

PMID:
30398401
3.

Methylation of protein aspartates and deamidated asparagines as a function of blood bank storage and oxidative stress in human red blood cells.

Reisz JA, Nemkov T, Dzieciatkowska M, Culp-Hill R, Stefanoni D, Hill RC, Yoshida T, Dunham A, Kanias T, Dumont LJ, Busch M, Eisenmesser EZ, Zimring JC, Hansen KC, D'Alessandro A.

Transfusion. 2018 Dec;58(12):2978-2991. doi: 10.1111/trf.14936. Epub 2018 Oct 12.

PMID:
30312994
4.

A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma.

Barnes JM, Kaushik S, Bainer RO, Sa JK, Woods EC, Kai F, Przybyla L, Lee M, Lee HW, Tung JC, Maller O, Barrett AS, Lu KV, Lakins JN, Hansen KC, Obernier K, Alvarez-Buylla A, Bergers G, Phillips JJ, Nam DH, Bertozzi CR, Weaver VM.

Nat Cell Biol. 2018 Oct;20(10):1203-1214. doi: 10.1038/s41556-018-0183-3. Epub 2018 Sep 10.

PMID:
30202050
5.

SILAC-MS Profiling of Reconstituted Human Chromatin Platforms for the Study of Transcription and RNA Regulation.

Balas MM, Porman AM, Hansen KC, Johnson AM.

J Proteome Res. 2018 Oct 5;17(10):3475-3484. doi: 10.1021/acs.jproteome.8b00395. Epub 2018 Sep 20.

PMID:
30192551
6.

A comparison of different methods of red blood cell leukoreduction and additive solutions on the accumulation of neutrophil-priming activity during storage.

Loi MM, Kelher M, Dzieciatkowska M, Hansen KC, Banerjee A, West FB, Stanley C, Briel M, Silliman CC.

Transfusion. 2018 Aug;58(8):2003-2012. doi: 10.1111/trf.14788. Epub 2018 Sep 1.

PMID:
30171813
7.

Targeted matrisome analysis identifies thrombospondin-2 and tenascin-C in aligned collagen stroma from invasive breast carcinoma.

Tomko LA, Hill RC, Barrett A, Szulczewski JM, Conklin MW, Eliceiri KW, Keely PJ, Hansen KC, Ponik SM.

Sci Rep. 2018 Aug 28;8(1):12941. doi: 10.1038/s41598-018-31126-w.

8.

Quantitative Profiling of the Lymph Node Clearance Capacity.

Clement CC, Wang W, Dzieciatkowska M, Cortese M, Hansen KC, Becerra A, Thangaswamy S, Nizamutdinova I, Moon JY, Stern LJ, Gashev AA, Zawieja D, Santambrogio L.

Sci Rep. 2018 Jul 26;8(1):11253. doi: 10.1038/s41598-018-29614-0.

9.

Krypton isotopes and noble gas abundances in the coma of comet 67P/Churyumov-Gerasimenko.

Rubin M, Altwegg K, Balsiger H, Bar-Nun A, Berthelier JJ, Briois C, Calmonte U, Combi M, De Keyser J, Fiethe B, Fuselier SA, Gasc S, Gombosi TI, Hansen KC, Kopp E, Korth A, Laufer D, Le Roy L, Mall U, Marty B, Mousis O, Owen T, Rème H, Sémon T, Tzou CY, Waite JH, Wurz P.

Sci Adv. 2018 Jul 4;4(7):eaar6297. doi: 10.1126/sciadv.aar6297. eCollection 2018 Jul.

10.

Glycogen synthase kinase-3 (GSK-3) activity regulates mRNA methylation in mouse embryonic stem cells.

Faulds KJ, Egelston JN, Sedivy LJ, Mitchell MK, Garimella S, Kozlowski H, D'Alessandro A, Hansen KC, Balsbaugh JL, Phiel CJ.

J Biol Chem. 2018 Jul 6;293(27):10731-10743. doi: 10.1074/jbc.RA117.001298. Epub 2018 May 18.

PMID:
29777057
11.

Author Correction: CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing.

Li X, Liu S, Jiang J, Zhang L, Espinosa S, Hill RC, Hansen KC, Zhou ZH, Zhao R.

Nat Commun. 2018 Apr 11;9(1):1495. doi: 10.1038/s41467-018-03708-9.

12.

When nature's robots go rogue: exploring protein homeostasis dysfunction and the implications for understanding human aging disease pathologies.

Reisz JA, Barrett AS, Nemkov T, Hansen KC, D'Alessandro A.

Expert Rev Proteomics. 2018 Apr;15(4):293-309. doi: 10.1080/14789450.2018.1453362. Epub 2018 Mar 21. Review.

PMID:
29540077
13.

Extracellular matrix in lung development, homeostasis and disease.

Zhou Y, Horowitz JC, Naba A, Ambalavanan N, Atabai K, Balestrini J, Bitterman PB, Corley RA, Ding BS, Engler AJ, Hansen KC, Hagood JS, Kheradmand F, Lin QS, Neptune E, Niklason L, Ortiz LA, Parks WC, Tschumperlin DJ, White ES, Chapman HA, Thannickal VJ.

Matrix Biol. 2018 Nov;73:77-104. doi: 10.1016/j.matbio.2018.03.005. Epub 2018 Mar 8. Review.

PMID:
29524630
14.

Correction: An autonomous metabolic role for Spen.

Hazegh KE, Nemkov T, D'Alessandro A, Diller JD, Monks J, McManaman JL, Jones KL, Hansen KC, Reis T.

PLoS Genet. 2018 Mar 6;14(3):e1007266. doi: 10.1371/journal.pgen.1007266. eCollection 2018 Mar.

15.

Red blood cell metabolism in Down syndrome: hints on metabolic derangements in aging.

Culp-Hill R, Zheng C, Reisz JA, Smith K, Rachubinski A, Nemkov T, Butcher E, Granrath R, Hansen KC, Espinosa JM, D'Alessandro A.

Blood Adv. 2017 Dec 21;1(27):2776-2780. doi: 10.1182/bloodadvances.2017011957. eCollection 2017 Dec 26.

16.

Red blood cells in hemorrhagic shock: a critical role for glutaminolysis in fueling alanine transamination in rats.

Reisz JA, Slaughter AL, Culp-Hill R, Moore EE, Silliman CC, Fragoso M, Peltz ED, Hansen KC, Banerjee A, D'Alessandro A.

Blood Adv. 2017 Jul 14;1(17):1296-1305. doi: 10.1182/bloodadvances.2017007187. eCollection 2017 Jul 25.

17.

Fibrinolysis shutdown is associated with a fivefold increase in mortality in trauma patients lacking hypersensitivity to tissue plasminogen activator.

Moore HB, Moore EE, Huebner BR, Dzieciatkowska M, Stettler GR, Nunns GR, Lawson PJ, Ghasabyan A, Chandler J, Banerjee A, Silliman C, Sauaia A, Hansen KC.

J Trauma Acute Care Surg. 2017 Dec;83(6):1014-1022. doi: 10.1097/TA.0000000000001718.

18.

Structure of the yeast spliceosomal postcatalytic P complex.

Liu S, Li X, Zhang L, Jiang J, Hill RC, Cui Y, Hansen KC, Zhou ZH, Zhao R.

Science. 2017 Dec 8;358(6368):1278-1283. doi: 10.1126/science.aar3462. Epub 2017 Nov 16.

19.

Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease.

Sun K, D'Alessandro A, Ahmed MH, Zhang Y, Song A, Ko TP, Nemkov T, Reisz JA, Wu H, Adebiyi M, Peng Z, Gong J, Liu H, Huang A, Wen YE, Wen AQ, Berka V, Bogdanov MV, Abdulmalik O, Han L, Tsai AL, Idowu M, Juneja HS, Kellems RE, Dowhan W, Hansen KC, Safo MK, Xia Y.

Sci Rep. 2017 Nov 10;7(1):15281. doi: 10.1038/s41598-017-13667-8.

20.

All animals are equal but some animals are more equal than others: Plasma lactate and succinate in hemorrhagic shock-A comparison in rodents, swine, nonhuman primates, and injured patients.

Reisz JA, Wither MJ, Moore EE, Slaughter AL, Moore HB, Ghasabyan A, Chandler J, Schaub LJ, Fragoso M, Nunns G, Silliman CC, Hansen KC, Banerjee A, Sheppard FR, D'Alessandro A.

J Trauma Acute Care Surg. 2018 Mar;84(3):537-541. doi: 10.1097/TA.0000000000001721.

PMID:
29112093
21.

Metabolism of Citrate and Other Carboxylic Acids in Erythrocytes As a Function of Oxygen Saturation and Refrigerated Storage.

Nemkov T, Sun K, Reisz JA, Yoshida T, Dunham A, Wen EY, Wen AQ, Roach RC, Hansen KC, Xia Y, D'Alessandro A.

Front Med (Lausanne). 2017 Oct 17;4:175. doi: 10.3389/fmed.2017.00175. eCollection 2017.

22.

Hypoxia modulates the purine salvage pathway and decreases red blood cell and supernatant levels of hypoxanthine during refrigerated storage.

Nemkov T, Sun K, Reisz JA, Song A, Yoshida T, Dunham A, Wither MJ, Francis RO, Roach RC, Dzieciatkowska M, Rogers SC, Doctor A, Kriebardis A, Antonelou M, Papassideri I, Young CT, Thomas TA, Hansen KC, Spitalnik SL, Xia Y, Zimring JC, Hod EA, D'Alessandro A.

Haematologica. 2018 Feb;103(2):361-372. doi: 10.3324/haematol.2017.178608. Epub 2017 Oct 27.

23.

CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing.

Li X, Liu S, Jiang J, Zhang L, Espinosa S, Hill RC, Hansen KC, Zhou ZH, Zhao R.

Nat Commun. 2017 Oct 19;8(1):1035. doi: 10.1038/s41467-017-01241-9. Erratum in: Nat Commun. 2018 Apr 11;9(1):1495.

24.

Hydroxylamine Chemical Digestion for Insoluble Extracellular Matrix Characterization.

Barrett AS, Wither MJ, Hill RC, Dzieciatkowska M, D'Alessandro A, Reisz JA, Hansen KC.

J Proteome Res. 2017 Nov 3;16(11):4177-4184. doi: 10.1021/acs.jproteome.7b00527.

25.

Glutaminase inhibition improves FLT3 inhibitor therapy for acute myeloid leukemia.

Gregory MA, Nemkov T, Reisz JA, Zaberezhnyy V, Hansen KC, D'Alessandro A, DeGregori J.

Exp Hematol. 2018 Feb;58:52-58. doi: 10.1016/j.exphem.2017.09.007. Epub 2017 Sep 22.

26.

Investigation of the effects of storage and freezing on mixes of heavy-labeled metabolite and amino acid standards.

Culp-Hill R, Reisz JA, Hansen KC, D'Alessandro A.

Rapid Commun Mass Spectrom. 2017 Dec 15;31(23):2030-2034. doi: 10.1002/rcm.7989.

27.

Folate dietary insufficiency and folic acid supplementation similarly impair metabolism and compromise hematopoiesis.

Henry CJ, Nemkov T, Casás-Selves M, Bilousova G, Zaberezhnyy V, Higa KC, Serkova NJ, Hansen KC, D'Alessandro A, DeGregori J.

Haematologica. 2017 Dec;102(12):1985-1994. doi: 10.3324/haematol.2017.171074. Epub 2017 Sep 7.

28.

The Metabolopathy of Tissue Injury, Hemorrhagic Shock, and Resuscitation in a Rat Model.

Slaughter AL, Nunns GR, D'Alessandro A, Banerjee A, Hansen KC, Moore EE, Silliman CC, Nemkov T, Moore HB, Fragoso M, Leasia K, Peltz ED.

Shock. 2018 May;49(5):580-590. doi: 10.1097/SHK.0000000000000948.

PMID:
28727610
29.

Blood and Plasma Proteomics: Targeted Quantitation and Posttranslational Redox Modifications.

Reisz JA, Chessler KM, Dzieciatkowska M, D'Alessandro A, Hansen KC.

Methods Mol Biol. 2017;1619:353-371. doi: 10.1007/978-1-4939-7057-5_24.

PMID:
28674896
30.

Prevalence of antimicrobial resistance and the cfiA resistance gene in Danish Bacteroides fragilis group isolates since 1973.

Ferløv-Schwensen SA, Sydenham TV, Hansen KCM, Hoegh SV, Justesen US.

Int J Antimicrob Agents. 2017 Oct;50(4):552-556. doi: 10.1016/j.ijantimicag.2017.05.007. Epub 2017 Jun 27.

PMID:
28666749
31.

An autonomous metabolic role for Spen.

Hazegh KE, Nemkov T, D'Alessandro A, Diller JD, Monks J, McManaman JL, Jones KL, Hansen KC, Reis T.

PLoS Genet. 2017 Jun 22;13(6):e1006859. doi: 10.1371/journal.pgen.1006859. eCollection 2017 Jun. Erratum in: PLoS Genet. 2018 Mar 6;14 (3):e1007266.

32.

Xenon isotopes in 67P/Churyumov-Gerasimenko show that comets contributed to Earth's atmosphere.

Marty B, Altwegg K, Balsiger H, Bar-Nun A, Bekaert DV, Berthelier JJ, Bieler A, Briois C, Calmonte U, Combi M, De Keyser J, Fiethe B, Fuselier SA, Gasc S, Gombosi TI, Hansen KC, Hässig M, Jäckel A, Kopp E, Korth A, Le Roy L, Mall U, Mousis O, Owen T, Rème H, Rubin M, Sémon T, Tzou CY, Waite JH, Wurz P.

Science. 2017 Jun 9;356(6342):1069-1072. doi: 10.1126/science.aal3496.

PMID:
28596364
33.

Plasma succinate is a predictor of mortality in critically injured patients.

DʼAlessandro A, Moore HB, Moore EE, Reisz JA, Wither MJ, Ghasasbyan A, Chandler J, Silliman CC, Hansen KC, Banerjee A.

J Trauma Acute Care Surg. 2017 Sep;83(3):491-495. doi: 10.1097/TA.0000000000001565.

34.

Characterization of rapid extraction protocols for high-throughput metabolomics.

Gehrke S, Reisz JA, Nemkov T, Hansen KC, D'Alessandro A.

Rapid Commun Mass Spectrom. 2017 Sep 15;31(17):1445-1452. doi: 10.1002/rcm.7916.

35.

Erythrocyte purinergic signaling components underlie hypoxia adaptation.

Sun K, Liu H, Song A, Manalo JM, D'Alessandro A, Hansen KC, Kellems RE, Eltzschig HK, Blackburn MR, Roach RC, Xia Y.

J Appl Physiol (1985). 2017 Oct 1;123(4):951-956. doi: 10.1152/japplphysiol.00155.2017. Epub 2017 Jun 1. Review.

36.

Antimicrobial resistance in the Bacteroides fragilis group in faecal samples from patients receiving broad-spectrum antibiotics.

Hansen KCM, Schwensen SAF, Henriksen DP, Justesen US, Sydenham TV.

Anaerobe. 2017 Oct;47:79-85. doi: 10.1016/j.anaerobe.2017.04.013. Epub 2017 Apr 23.

PMID:
28445776
37.

Red blood cell proteomics update: is there more to discover?

D'Alessandro A, Dzieciatkowska M, Nemkov T, Hansen KC.

Blood Transfus. 2017 Mar;15(2):182-187. doi: 10.2450/2017.0293-16. No abstract available.

38.

Omics markers of the red cell storage lesion and metabolic linkage.

D'alessandro A, Nemkov T, Reisz J, Dzieciatkowska M, Wither MJ, Hansen KC.

Blood Transfus. 2017 Mar;15(2):137-144. doi: 10.2450/2017.0341-16. Review.

39.

A three-minute method for high-throughput quantitative metabolomics and quantitative tracing experiments of central carbon and nitrogen pathways.

Nemkov T, Hansen KC, D'Alessandro A.

Rapid Commun Mass Spectrom. 2017 Apr 30;31(8):663-673. doi: 10.1002/rcm.7834.

40.

Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance.

Cavalli G, Justice JN, Boyle KE, D'Alessandro A, Eisenmesser EZ, Herrera JJ, Hansen KC, Nemkov T, Stienstra R, Garlanda C, Mantovani A, Seals DR, Dagna L, Joosten LA, Ballak DB, Dinarello CA.

Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):2313-2318. doi: 10.1073/pnas.1619011114. Epub 2017 Feb 13.

41.

Correlation of pre-operative plasma protein concentrations in cardiac surgery patients with bleeding outcomes using a targeted quantitative proteomics approach.

Clendenen N, Tollefson A, Dzieciatkowska M, Cambiaghi A, Ferrario M, Kroehl M, Banerjee A, D'Alessandro A, Hansen KC, Weitzel N.

Proteomics Clin Appl. 2017 Jul;11(7-8). doi: 10.1002/prca.201600175. Epub 2017 Mar 7.

42.

Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent.

Song A, Zhang Y, Han L, Yegutkin GG, Liu H, Sun K, D'Alessandro A, Li J, Karmouty-Quintana H, Iriyama T, Weng T, Zhao S, Wang W, Wu H, Nemkov T, Subudhi AW, Jameson-Van Houten S, Julian CG, Lovering AT, Hansen KC, Zhang H, Bogdanov M, Dowhan W, Jin J, Kellems RE, Eltzschig HK, Blackburn M, Roach RC, Xia Y.

Nat Commun. 2017 Feb 7;8:14108. doi: 10.1038/ncomms14108.

43.

CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming.

Kendrick AA, Schafer J, Dzieciatkowska M, Nemkov T, D'Alessandro A, Neelakantan D, Ford HL, Pearson CG, Weekes CD, Hansen KC, Eisenmesser EZ.

Oncotarget. 2017 Jan 24;8(4):6742-6762. doi: 10.18632/oncotarget.14272.

44.

Comfortably Numb and Back: Plasma Metabolomics Reveals Biochemical Adaptations in the Hibernating 13-Lined Ground Squirrel.

D'Alessandro A, Nemkov T, Bogren LK, Martin SL, Hansen KC.

J Proteome Res. 2017 Feb 3;16(2):958-969. doi: 10.1021/acs.jproteome.6b00884. Epub 2016 Dec 29.

PMID:
27991798
45.

The Rodent Liver Undergoes Weaning-Induced Involution and Supports Breast Cancer Metastasis.

Goddard ET, Hill RC, Nemkov T, D'Alessandro A, Hansen KC, Maller O, Mongoue-Tchokote S, Mori M, Partridge AH, Borges VF, Schedin P.

Cancer Discov. 2017 Feb;7(2):177-187. doi: 10.1158/2159-8290.CD-16-0822. Epub 2016 Dec 14.

46.

Rational design of a parthenolide-based drug regimen that selectively eradicates acute myelogenous leukemia stem cells.

Pei S, Minhajuddin M, D'Alessandro A, Nemkov T, Stevens BM, Adane B, Khan N, Hagen FK, Yadav VK, De S, Ashton JM, Hansen KC, Gutman JA, Pollyea DA, Crooks PA, Smith C, Jordan CT.

J Biol Chem. 2016 Nov 25;291(48):25280. No abstract available.

47.

The impact of an ICME on the Jovian X-ray aurora.

Dunn WR, Branduardi-Raymont G, Elsner RF, Vogt MF, Lamy L, Ford PG, Coates AJ, Gladstone GR, Jackman CM, Nichols JD, Rae IJ, Varsani A, Kimura T, Hansen KC, Jasinski JM.

J Geophys Res Space Phys. 2016 Mar;121(3):2274-2307. Epub 2016 Mar 22.

48.

Citrate metabolism in red blood cells stored in additive solution-3.

D'Alessandro A, Nemkov T, Yoshida T, Bordbar A, Palsson BO, Hansen KC.

Transfusion. 2017 Feb;57(2):325-336. doi: 10.1111/trf.13892. Epub 2016 Nov 4.

PMID:
27813142
49.

Mass Spectrometry-Based Bottom-Up Proteomics: Sample Preparation, LC-MS/MS Analysis, and Database Query Strategies.

Wither MJ, Hansen KC, Reisz JA.

Curr Protoc Protein Sci. 2016 Nov 1;86:16.4.1-16.4.20. doi: 10.1002/cpps.18.

PMID:
27801520
50.

ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia.

Gregory MA, D'Alessandro A, Alvarez-Calderon F, Kim J, Nemkov T, Adane B, Rozhok AI, Kumar A, Kumar V, Pollyea DA, Wempe MF, Jordan CT, Serkova NJ, Tan AC, Hansen KC, DeGregori J.

Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6669-E6678. Epub 2016 Oct 10.

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