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Extracranial activation of ATP-sensitive potassium channels induces vasodilation without nociceptive effects.

Al-Karagholi MA, Ghanizada H, Hansen JM, Aghazadeh S, Skovgaard LT, Olesen J, Ashina M.

Cephalalgia. 2019 Nov 7:333102419888490. doi: 10.1177/0333102419888490. [Epub ahead of print]


Levcromakalim, an Adenosine Triphosphate-Sensitive Potassium Channel Opener, Dilates Extracerebral but not Cerebral Arteries.

Al-Karagholi MA, Ghanizada H, Hansen JM, Skovgaard LT, Olesen J, Larsson HBW, Amin FM, Ashina M.

Headache. 2019 Oct;59(9):1468-1480. doi: 10.1111/head.13634. Epub 2019 Sep 18.


Ceramide: a novel inducer for neural tube defects.

Ross MM, Piorczynski TB, Harvey J, Burnham TS, Francis M, Larsen MW, Roe K, Hansen JM, Stark MR.

Dev Dyn. 2019 Oct;248(10):979-996. doi: 10.1002/dvdy.93. Epub 2019 Aug 28.


Opening of ATP-sensitive potassium channels causes migraine attacks: a new target for the treatment of migraine.

Al-Karagholi MA, Hansen JM, Guo S, Olesen J, Ashina M.

Brain. 2019 Sep 1;142(9):2644-2654. doi: 10.1093/brain/awz199.


Prescribing of proton-pump inhibitors: auditing the management and reasons for prescribing in Danish general practice.

Jarbøl DE, Lykkegaard J, Hansen JM, Munck A, Haastrup PF.

Fam Pract. 2019 Nov 18;36(6):758-764. doi: 10.1093/fampra/cmz025.


Migraine and the trigeminovascular system-40 years and counting.

Ashina M, Hansen JM, Do TP, Melo-Carrillo A, Burstein R, Moskowitz MA.

Lancet Neurol. 2019 Aug;18(8):795-804. doi: 10.1016/S1474-4422(19)30185-1. Epub 2019 May 31. Review.


Use of Primary Mouse Embryonic Fibroblasts in Developmental Toxicity Assessments.

Hansen JM, Piorczynski TB.

Methods Mol Biol. 2019;1965:7-17. doi: 10.1007/978-1-4939-9182-2_2.


More precise phenotyping of cluster headache using prospective attack reports.

Snoer AH, Lund N, Jensen RH, Kristoffersen ES, Barloese M, Hansen JM.

Eur J Neurol. 2019 Oct;26(10):1303-e85. doi: 10.1111/ene.13980. Epub 2019 Jun 2.


Radiation Dose Setting Method 2 and Modified Method 2: Use and Experience.

Hansen JM, Bryans TD.

Biomed Instrum Technol. 2019 Jun;53(s2):38-42. doi: 10.2345/0899-8205-53.s2.38. No abstract available.


Multitissue analysis of exercise and metformin on doxorubicin-induced iron dysregulation.

Mackay AD, Marchant ED, Munk DJ, Watt RK, Hansen JM, Thomson DM, Hancock CR.

Am J Physiol Endocrinol Metab. 2019 May 1;316(5):E922-E930. doi: 10.1152/ajpendo.00140.2018. Epub 2019 Mar 19.


The cost effectiveness of Helicobacter pylori population screening-economic evaluation alongside a randomised controlled trial with 13-year follow-up.

Høgh MB, Kronborg C, Hansen JM, Schaffalitzky de Muckadell OB.

Aliment Pharmacol Ther. 2019 Apr;49(8):1013-1025. doi: 10.1111/apt.15193. Epub 2019 Mar 10.


Red and orange flags for secondary headaches in clinical practice: SNNOOP10 list.

Do TP, Remmers A, Schytz HW, Schankin C, Nelson SE, Obermann M, Hansen JM, Sinclair AJ, Gantenbein AR, Schoonman GG.

Neurology. 2019 Jan 15;92(3):134-144. doi: 10.1212/WNL.0000000000006697. Epub 2018 Dec 26. Review.


Concordance of a laparoscopic scoring algorithm with primary surgery findings in advanced stage ovarian cancer.

Hansen JM, Sood AK, Coleman RL, Westin SN, Soliman PT, Ramirez PT, Fellman BM, Schmeler KM, Fleming ND.

Gynecol Oncol. 2018 Dec;151(3):428-432. doi: 10.1016/j.ygyno.2018.10.017. Epub 2018 Oct 23.


PRKRA/PACT Expression Promotes Chemoresistance of Mucinous Ovarian Cancer.

Hisamatsu T, McGuire M, Wu SY, Rupaimoole R, Pradeep S, Bayraktar E, Noh K, Hu W, Hansen JM, Lyons Y, Gharpure KM, Nagaraja AS, Mangala LS, Mitamura T, Rodriguez-Aguayo C, Eun YG, Rose J, Bartholomeusz G, Ivan C, Lee JS, Matsuo K, Frumovitz M, Wong KK, Lopez-Berestein G, Sood AK.

Mol Cancer Ther. 2019 Jan;18(1):162-172. doi: 10.1158/1535-7163.MCT-17-1050. Epub 2018 Oct 10.


Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) in the circulation after sumatriptan.

Hansen JM, Fahrenkrug J, Petersen J, Wienecke T, Olsen KS, Ashina M.

Scand J Pain. 2013 Oct 1;4(4):211-216. doi: 10.1016/j.sjpain.2013.04.002.


Mannose-binding lectin genotypes and outcome in end-stage renal disease: a prospective cohort study.

Adrian T, Hornum M, Eriksson F, Hansen JM, Pilely K, Garred P, Feldt-Rasmussen B.

Nephrol Dial Transplant. 2018 Nov 1;33(11):1991-1997. doi: 10.1093/ndt/gfy034.


Comparative analysis of lipid-mediated CRISPR-Cas9 genome editing techniques.

Ringer KP, Roth MG, Garey MS, Piorczynski TB, Suli A, Hansen JM, Alder JK.

Cell Biol Int. 2018 Jul;42(7):849-858. doi: 10.1002/cbin.10952. Epub 2018 Mar 14.


Cryo-EM structure of the bacterial actin AlfA reveals unique assembly and ATP-binding interactions and the absence of a conserved subdomain.

Usluer GD, DiMaio F, Yang SK, Hansen JM, Polka JK, Mullins RD, Kollman JM.

Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):3356-3361. doi: 10.1073/pnas.1715836115. Epub 2018 Feb 13.


Reply to: Correspondence regarding the impact of kidney transplantation on insulin sensitivity.

Jørgensen MB, Hornum M, van Hall G, Bistrup C, Hansen JM, Mathiesen ER, Feldt-Rasmussen B.

Transpl Int. 2018 Apr;31(4):458-459. doi: 10.1111/tri.13134. No abstract available.


Inhibiting Nuclear Phospho-Progesterone Receptor Enhances Antitumor Activity of Onapristone in Uterine Cancer.

Huang Y, Hu W, Huang J, Shen F, Sun Y, Ivan C, Pradeep S, Dood R, Haemmerle M, Jiang D, Mangala LS, Noh K, Hansen JM, Dalton HJ, Previs RA, Nagaraja AS, McGuire M, Jennings NB, Broaddus R, Coleman RL, Sood AK.

Mol Cancer Ther. 2018 Feb;17(2):464-473. doi: 10.1158/1535-7163.MCT-17-0006. Epub 2017 Dec 13.


Macrophage depletion through colony stimulating factor 1 receptor pathway blockade overcomes adaptive resistance to anti-VEGF therapy.

Lyons YA, Pradeep S, Wu SY, Haemmerle M, Hansen JM, Wagner MJ, Villar-Prados A, Nagaraja AS, Dood RL, Previs RA, Hu W, Zhao Y, Mak DH, Xiao Z, Melendez BD, Lizee GA, Mercado-Uribe I, Baggerly KA, Hwu P, Liu J, Overwijk WW, Coleman RL, Sood AK.

Oncotarget. 2017 Aug 24;8(57):96496-96505. doi: 10.18632/oncotarget.20410. eCollection 2017 Nov 14.


Human models of migraine - short-term pain for long-term gain.

Ashina M, Hansen JM, Á Dunga BO, Olesen J.

Nat Rev Neurol. 2017 Dec;13(12):713-724. doi: 10.1038/nrneurol.2017.137. Epub 2017 Oct 6. Review.


Redox stress and signaling during vertebrate embryonic development: Regulation and responses.

Timme-Laragy AR, Hahn ME, Hansen JM, Rastogi A, Roy MA.

Semin Cell Dev Biol. 2018 Aug;80:17-28. doi: 10.1016/j.semcdb.2017.09.019. Epub 2017 Sep 22. Review.


Monomeric cocoa catechins enhance β-cell function by increasing mitochondrial respiration.

Rowley TJ 4th, Bitner BF, Ray JD, Lathen DR, Smithson AT, Dallon BW, Plowman CJ, Bikman BT, Hansen JM, Dorenkott MR, Goodrich KM, Ye L, O'Keefe SF, Neilson AP, Tessem JS.

J Nutr Biochem. 2017 Nov;49:30-41. doi: 10.1016/j.jnutbio.2017.07.015. Epub 2017 Jul 27.


Cerebral hemodynamics in the different phases of migraine and cluster headache.

Hansen JM, Schankin CJ.

J Cereb Blood Flow Metab. 2019 Apr;39(4):595-609. doi: 10.1177/0271678X17729783. Epub 2017 Aug 31.


Macrophages Facilitate Resistance to Anti-VEGF Therapy by Altered VEGFR Expression.

Dalton HJ, Pradeep S, McGuire M, Hailemichael Y, Ma S, Lyons Y, Armaiz-Pena GN, Previs RA, Hansen JM, Rupaimoole R, Gonzalez-Villasana V, Cho MS, Wu SY, Mangala LS, Jennings NB, Hu W, Langley R, Mu H, Andreeff M, Bar-Eli M, Overwijk W, Ram P, Lopez-Berestein G, Coleman RL, Sood AK.

Clin Cancer Res. 2017 Nov 15;23(22):7034-7046. doi: 10.1158/1078-0432.CCR-17-0647. Epub 2017 Aug 29.


The KATP channel in migraine pathophysiology: a novel therapeutic target for migraine.

Al-Karagholi MA, Hansen JM, Severinsen J, Jansen-Olesen I, Ashina M.

J Headache Pain. 2017 Aug 23;18(1):90. doi: 10.1186/s10194-017-0800-8.


Platelets reduce anoikis and promote metastasis by activating YAP1 signaling.

Haemmerle M, Taylor ML, Gutschner T, Pradeep S, Cho MS, Sheng J, Lyons YM, Nagaraja AS, Dood RL, Wen Y, Mangala LS, Hansen JM, Rupaimoole R, Gharpure KM, Rodriguez-Aguayo C, Yim SY, Lee JS, Ivan C, Hu W, Lopez-Berestein G, Wong ST, Karlan BY, Levine DA, Liu J, Afshar-Kharghan V, Sood AK.

Nat Commun. 2017 Aug 21;8(1):310. doi: 10.1038/s41467-017-00411-z.


Randomized clinical trial: the impact of gastrointestinal risk factor screening and prophylactic proton pump inhibitor therapy in patients receiving dual antiplatelet therapy.

Jensen BES, Hansen JM, Larsen KS, Junker AB, Lassen JF, Jensen SE, Schaffalitzky de Muckadell OB.

Eur J Gastroenterol Hepatol. 2017 Oct;29(10):1118-1125. doi: 10.1097/MEG.0000000000000934.


Effects of Community Screening for Helicobacter pylori: 13-Year Follow-Up Evaluation of a Randomized Controlled Trial.

Bomme M, Hansen JM, Wildner-Christensen M, Hallas J, Schaffalitzky de Muckadell OB.

Clin Gastroenterol Hepatol. 2017 Nov;15(11):1715-1723.e7. doi: 10.1016/j.cgh.2017.06.006. Epub 2017 Jun 9.


The role of Nrf1 and Nrf2 in the regulation of glutathione and redox dynamics in the developing zebrafish embryo.

Sant KE, Hansen JM, Williams LM, Tran NL, Goldstone JV, Stegeman JJ, Hahn ME, Timme-Laragy A.

Redox Biol. 2017 Oct;13:207-218. doi: 10.1016/j.redox.2017.05.023. Epub 2017 May 30.


Human CTP synthase filament structure reveals the active enzyme conformation.

Lynch EM, Hicks DR, Shepherd M, Endrizzi JA, Maker A, Hansen JM, Barry RM, Gitai Z, Baldwin EP, Kollman JM.

Nat Struct Mol Biol. 2017 Jun;24(6):507-514. doi: 10.1038/nsmb.3407. Epub 2017 May 1.


Role of YAP1 as a Marker of Sensitivity to Dual AKT and P70S6K Inhibition in Ovarian and Uterine Malignancies.

Previs RA, Armaiz-Pena GN, Ivan C, Dalton HJ, Rupaimoole R, Hansen JM, Lyons Y, Huang J, Haemmerle M, Wagner MJ, Gharpure KM, Nagaraja AS, Filant J, McGuire MH, Noh K, Dorniak PL, Linesch SL, Mangala LS, Pradeep S, Wu SY, Sood AK.

J Natl Cancer Inst. 2017 Jul 1;109(7). doi: 10.1093/jnci/djw296.


Timing of developmental reduction in epithelial glutathione redox potential is associated with increased epithelial proliferation in the immature murine intestine.

Reid GK, Berardinelli AJ, Ray L, Jackson AR, Neish AS, Hansen JM, Denning PW.

Pediatr Res. 2017 Aug;82(2):362-369. doi: 10.1038/pr.2017.49. Epub 2017 Jun 7.


Insulin signaling via the PI3-kinase/Akt pathway regulates airway glucose uptake and barrier function in a CFTR-dependent manner.

Molina SA, Moriarty HK, Infield DT, Imhoff BR, Vance RJ, Kim AH, Hansen JM, Hunt WR, Koval M, McCarty NA.

Am J Physiol Lung Cell Mol Physiol. 2017 May 1;312(5):L688-L702. doi: 10.1152/ajplung.00364.2016. Epub 2017 Feb 17.


[Basic mechanisms of migraine and new methods of treatment].

Hansen JM, Ashina M.

Ugeskr Laeger. 2016 Dec 19;178(51). pii: V07160507. Review. Danish.


The impact of kidney transplantation on insulin sensitivity.

Jørgensen MB, Hornum M, van Hall G, Bistrup C, Hansen JM, Mathiesen ER, Feldt-Rasmussen B.

Transpl Int. 2017 Mar;30(3):295-304. doi: 10.1111/tri.12907. Epub 2017 Feb 9.


Molecular architecture of the yeast Elongator complex reveals an unexpected asymmetric subunit arrangement.

Setiaputra DT, Cheng DT, Lu S, Hansen JM, Dalwadi U, Lam CH, To JL, Dong MQ, Yip CK.

EMBO Rep. 2017 Feb;18(2):280-291. doi: 10.15252/embr.201642548. Epub 2016 Nov 21.


Snus and risk of gastroesophageal reflux. A population-based case-control study: the HUNT study.

Lie TM, Bomme M, Hveem K, Hansen JM, Ness-Jensen E.

Scand J Gastroenterol. 2017 Feb;52(2):193-198. doi: 10.1080/00365521.2016.1245775. Epub 2016 Oct 31.


A novel mouse model for the identification of thioredoxin-1 protein interactions.

Booze ML, Hansen JM, Vitiello PF.

Free Radic Biol Med. 2016 Oct;99:533-543. doi: 10.1016/j.freeradbiomed.2016.09.013. Epub 2016 Sep 14.


Antitumor and Antiangiogenic Effects of Aspirin-PC in Ovarian Cancer.

Huang Y, Lichtenberger LM, Taylor M, Bottsford-Miller JN, Haemmerle M, Wagner MJ, Lyons Y, Pradeep S, Hu W, Previs RA, Hansen JM, Fang D, Dorniak PL, Filant J, Dial EJ, Shen F, Hatakeyama H, Sood AK.

Mol Cancer Ther. 2016 Dec;15(12):2894-2904. Epub 2016 Sep 16.


Relationship between timing of endoscopy and mortality in patients with peptic ulcer bleeding: a nationwide cohort study.

Laursen SB, Leontiadis GI, Stanley AJ, Møller MH, Hansen JM, Schaffalitzky de Muckadell OB.

Gastrointest Endosc. 2017 May;85(5):936-944.e3. doi: 10.1016/j.gie.2016.08.049. Epub 2016 Sep 10.


Cancer risk and mortality after kidney transplantation: a population-based study on differences between Danish centres using standard immunosuppression with and without glucocorticoids.

Engberg H, Wehberg S, Bistrup C, Heaf J, Sørensen SS, Thiesson HC, Hansen JM, Svensson M, Green A, Marckmann P.

Nephrol Dial Transplant. 2016 Dec;31(12):2149-2156. Epub 2016 Sep 1.


General practice variation when initiating long-term prescribing of proton pump inhibitors: a nationwide cohort study.

Haastrup PF, Rasmussen S, Hansen JM, Christensen RD, Søndergaard J, Jarbøl DE.

BMC Fam Pract. 2016 May 28;17:57. doi: 10.1186/s12875-016-0460-9.


Nonhematopoietic Nrf2 dominantly impedes adult progression of sickle cell anemia in mice.

Ghosh S, Ihunnah CA, Hazra R, Walker AL, Hansen JM, Archer DR, Owusu-Ansah AT, Ofori-Acquah SF.

JCI Insight. 2016;1(4). pii: 81090. doi: 10.1172/jci.insight.81090. Epub 2016 Apr 7.


Medical and non-medical predictors of initiating long-term use of proton pump inhibitors: a nationwide cohort study of first-time users during a 10-year period.

Haastrup PF, Paulsen MS, Christensen RD, Søndergaard J, Hansen JM, Jarbøl DE.

Aliment Pharmacol Ther. 2016 Jul;44(1):78-87. doi: 10.1111/apt.13649. Epub 2016 May 3.


FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal.

Haemmerle M, Bottsford-Miller J, Pradeep S, Taylor ML, Choi HJ, Hansen JM, Dalton HJ, Stone RL, Cho MS, Nick AM, Nagaraja AS, Gutschner T, Gharpure KM, Mangala LS, Rupaimoole R, Han HD, Zand B, Armaiz-Pena GN, Wu SY, Pecot CV, Burns AR, Lopez-Berestein G, Afshar-Kharghan V, Sood AK.

J Clin Invest. 2016 May 2;126(5):1885-96. doi: 10.1172/JCI85086. Epub 2016 Apr 11.


Sodium Sulfide Attenuates Ischemic-Induced Heart Failure by Enhancing Proteasomal Function in an Nrf2-Dependent Manner.

Shimizu Y, Nicholson CK, Lambert JP, Barr LA, Kuek N, Herszenhaut D, Tan L, Murohara T, Hansen JM, Husain A, Naqvi N, Calvert JW.

Circ Heart Fail. 2016 Apr;9(4):e002368. doi: 10.1161/CIRCHEARTFAILURE.115.002368.


Targeting the tumour microenvironment in ovarian cancer.

Hansen JM, Coleman RL, Sood AK.

Eur J Cancer. 2016 Mar;56:131-143. doi: 10.1016/j.ejca.2015.12.016. Epub 2016 Feb 3. Review.

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