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Items: 1 to 50 of 179

1.

Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain (BET) Inhibitors Targeting a Methionine.

Kharenko OA, Patel RG, Brown SD, Calosing C, White A, Lakshminarasimhan D, Suto RK, Duffy BC, Kitchen DB, McLure KG, Hansen HC, van der Horst EH, Young PR.

J Med Chem. 2018 Sep 27;61(18):8202-8211. doi: 10.1021/acs.jmedchem.8b00666. Epub 2018 Sep 13.

PMID:
30165024
2.

An Instrument for Estimating the 6-Month Survival Probability After Whole-brain Irradiation Alone for Cerebral Metastases from Gynecological Cancer.

Janssen S, Hansen HC, Schild SE, Rades D.

Anticancer Res. 2018 Jun;38(6):3753-3756. doi: 10.21873/anticanres.12656.

PMID:
29848738
3.

Where does the toxicity come from in saponin extract?

Jiang X, Cao Y, Jørgensen LVG, Strobel BW, Hansen HCB, Cedergreen N.

Chemosphere. 2018 Aug;204:243-250. doi: 10.1016/j.chemosphere.2018.04.044. Epub 2018 Apr 10.

PMID:
29660537
4.

DGT technique to assess P mobilization from greenhouse vegetable soils in China: A novel approach.

Kalkhajeh YK, Sørensen H, Huang B, Guan DX, Luo J, Hu W, Holm PE, Hansen HCB.

Sci Total Environ. 2018 Jul 15;630:331-339. doi: 10.1016/j.scitotenv.2018.02.228. Epub 2018 Feb 23.

PMID:
29482141
5.

What is the aquatic toxicity of saponin-rich plant extracts used as biopesticides?

Jiang X, Hansen HCB, Strobel BW, Cedergreen N.

Environ Pollut. 2018 May;236:416-424. doi: 10.1016/j.envpol.2018.01.058.

PMID:
29414366
6.

Novel approaches to targeting BRD4.

Kharenko OA, Hansen HC.

Drug Discov Today Technol. 2017 Jun;24:19-24. doi: 10.1016/j.ddtec.2017.10.003. Epub 2017 Oct 28. Review.

PMID:
29233295
7.

Copper-mediated reductive dechlorination by green rust intercalated with dodecanoate.

Huang LZ, Yin Z, Cooper NGA, Yin W, Bjerglund ET, Strobel BW, Hansen HCB.

J Hazard Mater. 2018 Mar 5;345:18-26. doi: 10.1016/j.jhazmat.2017.11.011. Epub 2017 Nov 6.

PMID:
29128723
8.

RVX-297, a BET Bromodomain Inhibitor, Has Therapeutic Effects in Preclinical Models of Acute Inflammation and Autoimmune Disease.

Jahagirdar R, Attwell S, Marusic S, Bendele A, Shenoy N, McLure KG, Gilham D, Norek K, Hansen HC, Yu R, Tobin J, Wagner GS, Young PR, Wong NCW, Kulikowski E.

Mol Pharmacol. 2017 Dec;92(6):694-706. doi: 10.1124/mol.117.110379. Epub 2017 Sep 29.

PMID:
28974538
9.

Corrigendum to "Phosphorus saturation and mobilization in two typical Chinese greenhouse vegetable soils" [Chemosphere 172 (2017) 316-324].

Kalkhajeh YK, Huang B, Hu W, Holm PE, Hansen HCB.

Chemosphere. 2017 Nov;187:440-441. doi: 10.1016/j.chemosphere.2017.08.081. Epub 2017 Aug 31. No abstract available.

PMID:
28865705
10.

Wood Ash Induced pH Changes Strongly Affect Soil Bacterial Numbers and Community Composition.

Bang-Andreasen T, Nielsen JT, Voriskova J, Heise J, Rønn R, Kjøller R, Hansen HCB, Jacobsen CS.

Front Microbiol. 2017 Jul 28;8:1400. doi: 10.3389/fmicb.2017.01400. eCollection 2017.

11.

Selective removal of heavy metal ions by disulfide linked polymer networks.

Ko D, Lee JS, Patel HA, Jakobsen MH, Hwang Y, Yavuz CT, Hansen HCB, Andersen HR.

J Hazard Mater. 2017 Jun 15;332:140-148. doi: 10.1016/j.jhazmat.2017.03.007. Epub 2017 Mar 6.

PMID:
28285107
12.

Screening of inorganic and organic contaminants in floodwater in paddy fields of Hue and Thanh Hoa in Vietnam.

Trinh HT, Marcussen H, Hansen HC, Le GT, Duong HT, Ta NT, Nguyen TQ, Hansen S, Strobel BW.

Environ Sci Pollut Res Int. 2017 Mar;24(8):7348-7358. doi: 10.1007/s11356-017-8433-7. Epub 2017 Jan 20.

PMID:
28105594
13.

Glycine buffered synthesis of layered iron(II)-iron(III) hydroxides (green rusts).

Yin W, Huang L, Pedersen EB, Frandsen C, Hansen HCB.

J Colloid Interface Sci. 2017 Jul 1;497:429-438. doi: 10.1016/j.jcis.2016.11.076. Epub 2016 Nov 22.

PMID:
27894515
14.

Graphene oxide-mediated rapid dechlorination of carbon tetrachloride by green rust.

Huang LZ, Hansen HC, Daasbjerg K.

J Hazard Mater. 2017 Feb 5;323(Pt B):690-697. doi: 10.1016/j.jhazmat.2016.10.038. Epub 2016 Oct 18.

PMID:
27776856
15.

UPLC-MS/MS determination of ptaquiloside and pterosin B in preserved natural water.

Clauson-Kaas F, Hansen HC, Strobel BW.

Anal Bioanal Chem. 2016 Nov;408(28):7981-7990. Epub 2016 Sep 2.

PMID:
27590319
16.

Nitrogen regulation of the xyl genes of Pseudomonas putida mt-2 propagates into a significant effect of nitrate on m-xylene mineralization in soil.

Svenningsen NB, Nicolaisen MH, Hansen HC, de Lorenzo V, Nybroe O.

Microb Biotechnol. 2016 Nov;9(6):814-823. doi: 10.1111/1751-7915.12404. Epub 2016 Aug 26.

17.

Ptaquiloside from bracken in stream water at base flow and during storm events.

Clauson-Kaas F, Ramwell C, Hansen HCB, Strobel BW.

Water Res. 2016 Dec 1;106:155-162. doi: 10.1016/j.watres.2016.09.049. Epub 2016 Sep 26.

PMID:
27716466
18.

Dissipation of pterosin B in acid soils - Tracking the fate of the bracken fern carcinogen ptaquiloside.

Skourti-Stathaki E, Clauson-Kaas F, Brandt KK, Rasmussen LH, Hansen HCB.

Chemosphere. 2016 Dec;165:453-459. doi: 10.1016/j.chemosphere.2016.09.050. Epub 2016 Sep 30.

PMID:
27677121
19.

The Effects of Skill Training on Social Workers' Professional Competences in Norway: Results of a Cluster-Randomised Study.

Malmberg-Heimonen I, Natland S, Tøge AG, Hansen HC.

Br J Soc Work. 2016 Jul;46(5):1354-1371. Epub 2015 Sep 2.

20.

Concentrations of and health risks posed by polychlorinated dibenzo-p-dioxins and dibenzofurans around industrial sites in Hebei Province, China.

Han Y, Liu W, Hansen HC, Chen X, Liao X, Li H, Wang M, Yan N.

Environ Sci Pollut Res Int. 2016 Sep;23(18):18742-52. doi: 10.1007/s11356-016-7050-1. Epub 2016 Jun 17.

PMID:
27314421
21.

RVX-297- a novel BD2 selective inhibitor of BET bromodomains.

Kharenko OA, Gesner EM, Patel RG, Norek K, White A, Fontano E, Suto RK, Young PR, McLure KG, Hansen HC.

Biochem Biophys Res Commun. 2016 Aug 12;477(1):62-7. doi: 10.1016/j.bbrc.2016.06.021. Epub 2016 Jun 6.

PMID:
27282480
22.

Influence of long-range atmospheric transportation (LRAT) on mono-to octa-chlorinated PCDD/Fs levels and distributions in soil around Qinghai Lake, China.

Han Y, Liu W, Hansen HCB, Chen X, Liao X, Li H, Wang M, Yan N.

Chemosphere. 2016 Aug;156:143-149. doi: 10.1016/j.chemosphere.2016.04.110. Epub 2016 May 9.

PMID:
27174827
23.

Ptaquiloside in Irish Bracken Ferns and Receiving Waters, with Implications for Land Managers.

O'Driscoll C, Ramwell C, Harhen B, Morrison L, Clauson-Kaas F, Hansen HC, Campbell G, Sheahan J, Misstear B, Xiao L.

Molecules. 2016 Apr 26;21(5). pii: E543. doi: 10.3390/molecules21050543.

24.

Suspended particles only marginally reduce pyrethroid toxicity to the freshwater invertebrate Gammarus pulex (L.) during pulse exposure.

Rasmussen JJ, Cedergreen N, Kronvang B, Andersen MB, Nørum U, Kretschmann A, Strobel BW, Hansen HC.

Ecotoxicology. 2016 Apr;25(3):510-20. doi: 10.1007/s10646-016-1609-y. Epub 2016 Jan 29.

PMID:
26831865
25.

Electrochemical reduction of nitroaromatic compounds by single sheet iron oxide coated electrodes.

Huang LZ, Hansen HCB, Bjerrum MJ.

J Hazard Mater. 2016 Apr 5;306:175-183. doi: 10.1016/j.jhazmat.2015.12.009. Epub 2015 Dec 9.

PMID:
26716570
26.

Discovery of a new chemical series of BRD4(1) inhibitors using protein-ligand docking and structure-guided design.

Duffy BC, Liu S, Martin GS, Wang R, Hsia MM, Zhao H, Guo C, Ellis M, Quinn JF, Kharenko OA, Norek K, Gesner EM, Young PR, McLure KG, Wagner GS, Lakshminarasimhan D, White A, Suto RK, Hansen HC, Kitchen DB.

Bioorg Med Chem Lett. 2015 Jul 15;25(14):2818-23. doi: 10.1016/j.bmcl.2015.04.107. Epub 2015 May 11.

PMID:
26022843
27.

Coma and cerebral imaging.

Haupt WF, Hansen HC, Janzen RW, Firsching R, Galldiks N.

Springerplus. 2015 Apr 16;4:180. doi: 10.1186/s40064-015-0869-y. eCollection 2015.

28.

Thrombectomy vs. Systemic Thrombolysis in Acute Embolic Stroke with High Clot Burden: A Retrospective Analysis.

Meyne JK, Zimmermann PR, Rohr A, Riedel C, Hansen HC, Pulkowski U, Thie A, Holst T, Papengut F, Stingele R, Schepelmann K, Jansen O, Deuschl G, Binder A.

Rofo. 2015 Jul;187(7):555-60. doi: 10.1055/s-0034-1399222. Epub 2015 Apr 1.

29.

Land management of bracken needs to account for bracken carcinogens--a case study from Britain.

Rasmussen LH, Donnelly E, Strobel BW, Holm PE, Hansen HC.

J Environ Manage. 2015 Mar 15;151:258-66. doi: 10.1016/j.jenvman.2014.12.052. Epub 2015 Jan 9.

PMID:
25577704
30.

A novel BET bromodomain inhibitor, RVX-208, shows reduction of atherosclerosis in hyperlipidemic ApoE deficient mice.

Jahagirdar R, Zhang H, Azhar S, Tobin J, Attwell S, Yu R, Wu J, McLure KG, Hansen HC, Wagner GS, Young PR, Srivastava RA, Wong NC, Johansson J.

Atherosclerosis. 2014 Sep;236(1):91-100. doi: 10.1016/j.atherosclerosis.2014.06.008. Epub 2014 Jun 28.

PMID:
25016363
31.

BET and HDAC inhibitors induce similar genes and biological effects and synergize to kill in Myc-induced murine lymphoma.

Bhadury J, Nilsson LM, Muralidharan SV, Green LC, Li Z, Gesner EM, Hansen HC, Keller UB, McLure KG, Nilsson JA.

Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):E2721-30. doi: 10.1073/pnas.1406722111. Epub 2014 Jun 16.

32.

Opioid overuse pain syndrome.

Manchikanti L, Atluri S, Boswell MV, Hansen HC.

J Opioid Manag. 2014 Mar-Apr;10(2):81. No abstract available.

PMID:
24946369
33.

Phosphate sorption by three potential filter materials as assessed by isothermal titration calorimetry.

Lyngsie G, Penn CJ, Hansen HC, Borggaard OK.

J Environ Manage. 2014 Oct 1;143:26-33. doi: 10.1016/j.jenvman.2014.04.010. Epub 2014 May 13.

PMID:
24833525
34.

Determination of ptaquiloside and pterosin B derived from bracken (Pteridium aquilinum) in cattle plasma, urine and milk.

Aranha PC, Hansen HC, Rasmussen LH, Strobel BW, Friis C.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Mar 1;951-952:44-51. doi: 10.1016/j.jchromb.2014.01.022. Epub 2014 Jan 23.

PMID:
24508676
35.

The naturally occurring carcinogen ptaquiloside is present in groundwater below bracken vegetation.

Clauson-Kaas F, Jensen PH, Jacobsen OS, Juhler RK, Hansen HC.

Environ Toxicol Chem. 2014 May;33(5):1030-4. doi: 10.1002/etc.2533. Epub 2014 Mar 12.

PMID:
24464773
36.

RVX-208, an inducer of ApoA-I in humans, is a BET bromodomain antagonist.

McLure KG, Gesner EM, Tsujikawa L, Kharenko OA, Attwell S, Campeau E, Wasiak S, Stein A, White A, Fontano E, Suto RK, Wong NC, Wagner GS, Hansen HC, Young PR.

PLoS One. 2013 Dec 31;8(12):e83190. doi: 10.1371/journal.pone.0083190. eCollection 2013.

37.

A three-step test of phosphate sorption efficiency of potential agricultural drainage filter materials.

Lyngsie G, Borggaard OK, Hansen HC.

Water Res. 2014 Mar 15;51:256-65. doi: 10.1016/j.watres.2013.10.061. Epub 2013 Nov 8.

PMID:
24275107
38.

Optic disc edema in an astronaut after repeat long-duration space flight.

Mader TH, Gibson CR, Pass AF, Lee AG, Killer HE, Hansen HC, Dervay JP, Barratt MR, Tarver WJ, Sargsyan AE, Kramer LA, Riascos R, Bedi DG, Pettit DR.

J Neuroophthalmol. 2013 Sep;33(3):249-55. doi: 10.1097/WNO.0b013e31829b41a6.

PMID:
23851997
39.

Adsorption of the disinfectant benzalkonium chloride on montmorillonite. Synergistic effect in mixture of molecules with different chain lengths.

Zanini GP, Ovesen RG, Hansen HC, Strobel BW.

J Environ Manage. 2013 Oct 15;128:100-5. doi: 10.1016/j.jenvman.2013.04.056. Epub 2013 May 27.

PMID:
23722179
40.

In vitro biosynthesis, isolation, and identification of predominant metabolites of 2-(4-(2-hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethoxyquinazolin-4(3H)-one (RVX-208).

Khmelnitsky YL, Mozhaev VV, Cotterill IC, Michels PC, Boudjabi S, Khlebnikov V, Madhava Reddy M, Wagner GS, Hansen HC.

Eur J Med Chem. 2013 Jun;64:121-8. doi: 10.1016/j.ejmech.2013.03.062. Epub 2013 Apr 10.

PMID:
23644195
41.

Persistent intrathecal antibody synthesis 15 years after recovering from anti-N-methyl-D-aspartate receptor encephalitis.

Hansen HC, Klingbeil C, Dalmau J, Li W, Weissbrich B, Wandinger KP.

JAMA Neurol. 2013 Jan;70(1):117-9. doi: 10.1001/jamaneurol.2013.585.

42.

Adsorption of mono- and di-butyltin by a wheat charcoal: pH effects and modeling.

Fang L, Borggaard OK, Christensen JH, Holm PE, Hansen HC.

Chemosphere. 2012 Oct;89(7):863-8. doi: 10.1016/j.chemosphere.2012.05.010. Epub 2012 Jun 2.

PMID:
22664389
43.

[Remission of incomplete paraplegia after thoracic stent graft implantation. Case report and review of the literature].

Jacobs A, Jahnke T, Baum H, Brammer H, Hansen HC.

Nervenarzt. 2012 Apr;83(4):506-9. doi: 10.1007/s00115-011-3406-4. Review. German. No abstract available.

PMID:
22525972
44.

Efficient dechlorination of carbon tetrachloride by hydrophobic green rust intercalated with dodecanoate anions.

Ayala-Luis KB, Cooper NG, Koch CB, Hansen HC.

Environ Sci Technol. 2012 Mar 20;46(6):3390-7. doi: 10.1021/es204368u. Epub 2012 Mar 7. Erratum in: Environ Sci Technol. 2012 Apr 17;46(8):4683.

PMID:
22360442
45.

Pteridium aquilinum and its ptaquiloside toxin induce DNA damage response in gastric epithelial cells, a link with gastric carcinogenesis.

Gomes J, Magalhães A, Michel V, Amado IF, Aranha P, Ovesen RG, Hansen HC, Gärtner F, Reis CA, Touati E.

Toxicol Sci. 2012 Mar;126(1):60-71. doi: 10.1093/toxsci/kfr329. Epub 2011 Dec 5.

PMID:
22143989
46.

A liquid chromatography-electrospray ionization-mass spectrometry method for quantification of cyclotides in plants avoiding sorption during sample preparation.

Ovesen RG, Göransson U, Hansen SH, Nielsen J, Hansen HC.

J Chromatogr A. 2011 Nov 4;1218(44):7964-70. doi: 10.1016/j.chroma.2011.08.095. Epub 2011 Sep 8.

PMID:
21944848
47.

Toxicity and uptake of TRI- and dibutyltin in Daphnia magna in the absence and presence of nano-charcoal.

Fang L, Borggaard OK, Holm PE, Hansen HC, Cedergreen N.

Environ Toxicol Chem. 2011 Nov;30(11):2553-61. doi: 10.1002/etc.649. Epub 2011 Sep 8.

PMID:
21858855
48.

Biomedicine in the environment: sorption of the cyclotide kalata B2 to montmorillonite, goethite, and humic acid.

Ovesen RG, Nielsen J, Hansen HC.

Environ Toxicol Chem. 2011 Aug;30(8):1785-92. doi: 10.1002/etc.579. Epub 2011 Jun 3.

PMID:
21590795
49.

[Posthypoxic apallic syndrome].

Hansen HC.

Nervenarzt. 2011 Jun;82(6):785-6. doi: 10.1007/s00115-011-3303-x. German. No abstract available.

PMID:
21562907
50.

The use of environmental metabolomics to determine glyphosate level of exposure in rapeseed (Brassica napus L.) seedlings.

Petersen IL, Tomasi G, Sørensen H, Boll ES, Hansen HC, Christensen JH.

Environ Pollut. 2011 Oct;159(10):3071-7. doi: 10.1016/j.envpol.2011.04.005. Epub 2011 May 8.

PMID:
21555174

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