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Items: 1 to 50 of 233

1.

IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis.

Starkey MR, Plank MW, Casolari P, Papi A, Pavlidis S, Guo Y, Cameron GJM, Haw TJ, Tam A, Obiedat M, Donovan C, Hansbro NG, Nguyen DH, Nair PM, Kim RY, Horvat JC, Kaiko GE, Durum SK, Wark PA, Sin DD, Caramori G, Adcock IM, Foster PS, Hansbro PM.

Eur Respir J. 2019 Jun 13. pii: 1800174. doi: 10.1183/13993003.00174-2018. [Epub ahead of print]

PMID:
31196943
2.

Oligonucleotide therapy: An emerging focus area for drug delivery in chronic inflammatory respiratory diseases.

Mehta M, Deeksha, Tewari D, Gupta G, Awasthi R, Singh H, Pandey P, Chellappan DK, Wadhwa R, Collet T, Hansbro PM, Kumar SR, Thangavelu L, Negi P, Dua K, Satija S.

Chem Biol Interact. 2019 May 25;308:206-215. doi: 10.1016/j.cbi.2019.05.028. [Epub ahead of print] Review.

PMID:
31136735
3.

Chitinase-like protein YKL-40 correlates with inflammatory phenotypes, anti-asthma responsiveness and future exacerbations.

Liu L, Zhang X, Liu Y, Zhang L, Zheng J, Wang J, Hansbro PM, Wang L, Wang G, Hsu AC.

Respir Res. 2019 May 22;20(1):95. doi: 10.1186/s12931-019-1051-9.

4.

Polycomb repressive complex 2 is a critical mediator of allergic inflammation.

Keenan CR, Iannarella N, Garnham AL, Brown AC, Kim RY, Horvat JC, Hansbro PM, Nutt SL, Allan RS.

JCI Insight. 2019 May 16;4(10). pii: 127745. doi: 10.1172/jci.insight.127745. eCollection 2019 May 16.

5.

Molecular links between COPD and lung cancer: new targets for drug discovery?

Caramori G, Ruggeri P, Mumby S, Ieni A, Lo Bello F, Chimankar V, Donovan C, Andò F, Nucera F, Coppolino I, Tuccari G, Hansbro PM, Adcock IM.

Expert Opin Ther Targets. 2019 Jun;23(6):539-553. doi: 10.1080/14728222.2019.1615884. Epub 2019 May 11.

PMID:
31079559
6.

Group 2 Innate Lymphoid Cells Are Redundant in Experimental Renal Ischemia-Reperfusion Injury.

Cameron GJM, Cautivo KM, Loering S, Jiang SH, Deshpande AV, Foster PS, McKenzie ANJ, Molofsky AB, Hansbro PM, Starkey MR.

Front Immunol. 2019 Apr 16;10:826. doi: 10.3389/fimmu.2019.00826. eCollection 2019.

7.

Platelet activating factor receptor regulates colitis-induced pulmonary inflammation through the NLRP3 inflammasome.

Liu G, Mateer SW, Hsu A, Goggins BJ, Tay H, Mathe A, Fan K, Neal R, Bruce J, Burns G, Minahan K, Maltby S, Fricker M, Foster PS, Wark PAB, Hansbro PM, Keely S.

Mucosal Immunol. 2019 Apr 11. doi: 10.1038/s41385-019-0163-3. [Epub ahead of print]

PMID:
30976089
8.

Functional effects of the microbiota in chronic respiratory disease.

Budden KF, Shukla SD, Rehman SF, Bowerman KL, Keely S, Hugenholtz P, Armstrong-James DPH, Adcock IM, Chotirmall SH, Chung KF, Hansbro PM.

Lancet Respir Med. 2019 Apr 8. pii: S2213-2600(18)30510-1. doi: 10.1016/S2213-2600(18)30510-1. [Epub ahead of print] Review.

PMID:
30975495
9.

Identification of biomarkers and genetic approaches toward chronic obstructive pulmonary disease.

Wadhwa R, Aggarwal T, Malyla V, Kumar N, Gupta G, Chellappan DK, Dureja H, Mehta M, Satija S, Gulati M, Maurya PK, Collet T, Hansbro PM, Dua K.

J Cell Physiol. 2019 Mar 25. doi: 10.1002/jcp.28482. [Epub ahead of print] Review.

PMID:
30912142
10.

Evaluating recruitment strategies for AUSPICE, a large Australian community-based randomised controlled trial.

Peel R, Ren S, Hure A, Evans TJ, D'Este CA, Abhayaratna WP, Tonkin AM, Hopper I, Thrift AG, Levi CR, Sturm J, Durrheim D, Hung J, Briffa TG, Chew DP, Anderson P, Moon L, McEvoy M, Hansbro PM, Newby DA, Attia JR.

Med J Aust. 2019 May;210(9):409-415. doi: 10.5694/mja2.50117. Epub 2019 Mar 25.

PMID:
30907001
11.

Current Status on Immunological Therapies for Type 1 Diabetes Mellitus.

Xin GLL, Khee YP, Ying TY, Chellian J, Gupta G, Kunnath AP, Nammi S, Collet T, Hansbro PM, Dua K, Chellappan DK.

Curr Diab Rep. 2019 Mar 23;19(5):22. doi: 10.1007/s11892-019-1144-3. Review.

PMID:
30905013
12.

Interactions with the macrophages: An emerging targeted approach using novel drug delivery systems in respiratory diseases.

Mehta M, Deeksha, Sharma N, Vyas M, Khurana N, Maurya PK, Singh H, Andreoli de Jesus TP, Dureja H, Chellappan DK, Gupta G, Wadhwa R, Collet T, Hansbro PM, Dua K, Satija S.

Chem Biol Interact. 2019 May 1;304:10-19. doi: 10.1016/j.cbi.2019.02.021. Epub 2019 Mar 5. Review.

PMID:
30849336
13.

Novel role of extracellular matrix protein 1 (ECM1) in cardiac aging and myocardial infarction.

Hardy SA, Mabotuwana NS, Murtha LA, Coulter B, Sanchez-Bezanilla S, Al-Omary MS, Senanayake T, Loering S, Starkey M, Lee RJ, Rainer PP, Hansbro PM, Boyle AJ.

PLoS One. 2019 Feb 21;14(2):e0212230. doi: 10.1371/journal.pone.0212230. eCollection 2019.

14.

TRAIL signals through the ubiquitin ligase MID1 to promote pulmonary fibrosis.

Collison AM, Li J, de Siqueira AP, Lv X, Toop HD, Morris JC, Starkey MR, Hansbro PM, Zhang J, Mattes J.

BMC Pulm Med. 2019 Feb 7;19(1):31. doi: 10.1186/s12890-019-0786-x.

15.

Emerging therapeutic potential of group 2 innate lymphoid cells in acute kidney injury.

Cameron GJM, Jiang SH, Loering S, Deshpande AV, Hansbro PM, Starkey MR.

J Pathol. 2019 May;248(1):9-15. doi: 10.1002/path.5242. Epub 2019 Mar 5. Review.

PMID:
30684265
16.

Pulmonary group 2 innate lymphoid cells: surprises and challenges.

Starkey MR, McKenzie AN, Belz GT, Hansbro PM.

Mucosal Immunol. 2019 Mar;12(2):299-311. doi: 10.1038/s41385-018-0130-4. Epub 2019 Jan 21. Review.

PMID:
30664706
17.

Dietary Fatty Acids Amplify Inflammatory Responses to Infection through p38 MAPK Signaling.

Rutting S, Zakarya R, Bozier J, Xenaki D, Horvat JC, Wood LG, Hansbro PM, Oliver BG.

Am J Respir Cell Mol Biol. 2019 May;60(5):554-568. doi: 10.1165/rcmb.2018-0215OC.

PMID:
30648905
18.

STAT3 Regulates the Onset of Oxidant-Induced Senescence in Lung Fibroblasts.

Waters DW, Blokland KEC, Pathinayake PS, Wei L, Schuliga M, Jaffar J, Westall GP, Hansbro PM, Prele CM, Mutsaers SE, Bartlett NW, Burgess JK, Grainge CL, Knight DA.

Am J Respir Cell Mol Biol. 2019 Jan 4. doi: 10.1165/rcmb.2018-0328OC. [Epub ahead of print]

PMID:
30608861
19.

Targeting microRNAs using nanotechnology in pulmonary diseases.

Dua K, Chellappan DK, Singhvi G, de Jesus Andreoli Pinto T, Gupta G, Hansbro PM.

Panminerva Med. 2018 Dec;60(4):230-231. doi: 10.23736/S0031-0808.18.03459-6. No abstract available.

PMID:
30563304
20.

Mechanisms and Management of Asthma Exacerbations.

Ramsahai JM, Hansbro PM, Wark PAB.

Am J Respir Crit Care Med. 2019 Feb 15;199(4):423-432. doi: 10.1164/rccm.201810-1931CI.

PMID:
30562041
21.

Increasing complexity and interactions of oxidative stress in chronic respiratory diseases: An emerging need for novel drug delivery systems.

Dua K, Malyla V, Singhvi G, Wadhwa R, Krishna RV, Shukla SD, Shastri MD, Chellappan DK, Maurya PK, Satija S, Mehta M, Gulati M, Hansbro N, Collet T, Awasthi R, Gupta G, Hsu A, Hansbro PM.

Chem Biol Interact. 2019 Feb 1;299:168-178. doi: 10.1016/j.cbi.2018.12.009. Epub 2018 Dec 13. Review.

PMID:
30553721
22.

Molecular modulators of celastrol as the keystones for its diverse pharmacological activities.

Ng SW, Chan Y, Chellappan DK, Madheswaran T, Zeeshan F, Chan YL, Collet T, Gupta G, Oliver BG, Wark P, Hansbro N, Hsu A, Hansbro PM, Dua K, Panneerselvam J.

Biomed Pharmacother. 2019 Jan;109:1785-1792. doi: 10.1016/j.biopha.2018.11.051. Epub 2018 Nov 26. Review.

23.

TRPA1: A potential target for cold-induced airway disease?

Donovan C, Hansbro PM.

Respirology. 2019 Mar;24(3):193-194. doi: 10.1111/resp.13453. Epub 2018 Dec 13. No abstract available.

24.

Characterisation of small molecule ligands 4CMTB and 2CTAP as modulators of human FFA2 receptor signalling.

Schofield ZV, Croker D, Robertson AAB, Massey NL, Donovan C, Tee E, Edwards D, Woodruff TM, Halai R, Hansbro PM, Cooper MA.

Sci Rep. 2018 Dec 13;8(1):17819. doi: 10.1038/s41598-018-36242-1.

25.

Lung development and emerging roles for type 2 immunity.

Loering S, Cameron GJM, Starkey MR, Hansbro PM.

J Pathol. 2019 Apr;247(5):686-696. doi: 10.1002/path.5211. Epub 2019 Jan 16. Review.

PMID:
30506724
26.

The role of environmental exposure to non-cigarette smoke in lung disease.

Kc R, Shukla SD, Gautam SS, Hansbro PM, O'Toole RF.

Clin Transl Med. 2018 Dec 5;7(1):39. doi: 10.1186/s40169-018-0217-2. Review.

27.

Heparin-binding epidermal growth factor (HB-EGF) drives EMT in patients with COPD: implications for disease pathogenesis and novel therapies.

Eapen MS, Sharma P, Thompson IE, Lu W, Myers S, Hansbro PM, Sohal SS.

Lab Invest. 2019 Feb;99(2):150-157. doi: 10.1038/s41374-018-0146-0. Epub 2018 Nov 19. Review.

PMID:
30451982
28.

Targeting bacterial biofilms in pulmonary diseases in pediatric population.

Dua K, Gupta G, Chellappan DK, Shukla S, Hansbro PM.

Minerva Pediatr. 2019 Jun;71(3):309-310. doi: 10.23736/S0026-4946.18.05256-8. Epub 2018 Nov 7. No abstract available.

PMID:
30419743
29.

Short-chain fatty acids increase TNFα-induced inflammation in primary human lung mesenchymal cells through the activation of p38 MAPK.

Rutting S, Xenaki D, Malouf M, Horvat JC, Wood LG, Hansbro PM, Oliver BG.

Am J Physiol Lung Cell Mol Physiol. 2019 Jan 1;316(1):L157-L174. doi: 10.1152/ajplung.00306.2018. Epub 2018 Nov 8.

PMID:
30407866
30.

Azithromycin treatment modifies airway and blood gene expression networks in neutrophilic COPD.

Baines KJ, Wright TK, Gibson PG, Powell H, Hansbro PM, Simpson JL.

ERJ Open Res. 2018 Nov 5;4(4). pii: 00031-2018. doi: 10.1183/23120541.00031-2018. eCollection 2018 Oct.

31.

Role of Oxidative Stress in the Pathology and Management of Human Tuberculosis.

Shastri MD, Shukla SD, Chong WC, Dua K, Peterson GM, Patel RP, Hansbro PM, Eri R, O'Toole RF.

Oxid Med Cell Longev. 2018 Oct 11;2018:7695364. doi: 10.1155/2018/7695364. eCollection 2018. Review.

32.

Chronic Obstructive Pulmonary Disease and Lung Cancer: Underlying Pathophysiology and New Therapeutic Modalities.

Eapen MS, Hansbro PM, Larsson-Callerfelt AK, Jolly MK, Myers S, Sharma P, Jones B, Rahman MA, Markos J, Chia C, Larby J, Haug G, Hardikar A, Weber HC, Mabeza G, Cavalheri V, Khor YH, McDonald CF, Sohal SS.

Drugs. 2018 Nov;78(16):1717-1740. doi: 10.1007/s40265-018-1001-8. Review.

PMID:
30392114
33.

Dietary ω-6 polyunsaturated fatty acid arachidonic acid increases inflammation, but inhibits ECM protein expression in COPD.

Rutting S, Papanicolaou M, Xenaki D, Wood LG, Mullin AM, Hansbro PM, Oliver BG.

Respir Res. 2018 Nov 3;19(1):211. doi: 10.1186/s12931-018-0919-4.

34.

Gene therapy and type 1 diabetes mellitus.

Chellappan DK, Sivam NS, Teoh KX, Leong WP, Fui TZ, Chooi K, Khoo N, Yi FJ, Chellian J, Cheng LL, Dahiya R, Gupta G, Singhvi G, Nammi S, Hansbro PM, Dua K.

Biomed Pharmacother. 2018 Dec;108:1188-1200. doi: 10.1016/j.biopha.2018.09.138. Epub 2018 Oct 2. Review.

35.

Dysfunctional Immunity and Microbial Adhesion Molecules in Smoking-induced Pneumonia.

Eapen MS, Sharma P, Moodley YP, Hansbro PM, Sohal SS.

Am J Respir Crit Care Med. 2019 Jan 15;199(2):250-251. doi: 10.1164/rccm.201808-1553LE. No abstract available.

PMID:
30290125
36.

Roles for T/B lymphocytes and ILC2s in experimental chronic obstructive pulmonary disease.

Donovan C, Starkey MR, Kim RY, Rana BMJ, Barlow JL, Jones B, Haw TJ, Mono Nair P, Budden K, Cameron GJM, Horvat JC, Wark PA, Foster PS, McKenzie ANJ, Hansbro PM.

J Leukoc Biol. 2019 Jan;105(1):143-150. doi: 10.1002/JLB.3AB0518-178R. Epub 2018 Sep 27.

37.

An Overview of Circular RNAs.

Awasthi R, Singh AK, Mishra G, Maurya A, Chellappan DK, Gupta G, Hansbro PM, Dua K.

Adv Exp Med Biol. 2018;1087:3-14. doi: 10.1007/978-981-13-1426-1_1. Review.

PMID:
30259353
38.

Multi-drug resistant Mycobacterium tuberculosis & oxidative stress complexity: Emerging need for novel drug delivery approaches.

Dua K, Rapalli VK, Shukla SD, Singhvi G, Shastri MD, Chellappan DK, Satija S, Mehta M, Gulati M, Pinto TJA, Gupta G, Hansbro PM.

Biomed Pharmacother. 2018 Nov;107:1218-1229. doi: 10.1016/j.biopha.2018.08.101. Epub 2018 Aug 29. Review.

PMID:
30257336
39.

The Overlap of Lung Tissue Transcriptome of Smoke Exposed Mice with Human Smoking and COPD.

Obeidat M, Dvorkin-Gheva A, Li X, Bossé Y, Brandsma CA, Nickle DC, Hansbro PM, Faner R, Agusti A, Paré PD, Stampfli MR, Sin DD.

Sci Rep. 2018 Aug 8;8(1):11881. doi: 10.1038/s41598-018-30313-z.

40.

Modification of Crocodile Spermatozoa Refutes the Tenet That Post-testicular Sperm Maturation Is Restricted To Mammals.

Nixon B, Johnston SD, Skerrett-Byrne DA, Anderson AL, Stanger SJ, Bromfield EG, Martin JH, Hansbro PM, Dun MD.

Mol Cell Proteomics. 2019 Mar 15;18(Suppl 1):S59-S76. doi: 10.1074/mcp.RA118.000904. Epub 2018 Aug 2.

PMID:
30072580
41.

Influenza A virus infection dysregulates the expression of microRNA-22 and its targets; CD147 and HDAC4, in epithelium of asthmatics.

Moheimani F, Koops J, Williams T, Reid AT, Hansbro PM, Wark PA, Knight DA.

Respir Res. 2018 Aug 2;19(1):145. doi: 10.1186/s12931-018-0851-7.

42.

Targeting MicroRNAs: Promising Future Therapeutics in the Treatment of Allergic Airway Disease.

Dua K, Hansbro NG, Foster PS, Hansbro PM.

Crit Rev Eukaryot Gene Expr. 2018;28(2):125-127. doi: 10.1615/CritRevEukaryotGeneExpr.2018022218.

PMID:
30055538
43.

Saturated fatty acids, obesity, and the nucleotide oligomerization domain-like receptor protein 3 (NLRP3) inflammasome in asthmatic patients.

Wood LG, Li Q, Scott HA, Rutting S, Berthon BS, Gibson PG, Hansbro PM, Williams E, Horvat J, Simpson JL, Young P, Oliver BG, Baines KJ.

J Allergy Clin Immunol. 2019 Jan;143(1):305-315. doi: 10.1016/j.jaci.2018.04.037. Epub 2018 May 30.

PMID:
29857009
44.

Microbiome as therapeutics in vesicular delivery.

Singhvi G, Girdhar V, Patil S, Gupta G, Hansbro PM, Dua K.

Biomed Pharmacother. 2018 Aug;104:738-741. doi: 10.1016/j.biopha.2018.05.099. Epub 2018 May 29. Review.

PMID:
29807223
45.

Functional relevance of SATB1 in immune regulation and tumorigenesis.

Sunkara KP, Gupta G, Hansbro PM, Dua K, Bebawy M.

Biomed Pharmacother. 2018 Aug;104:87-93. doi: 10.1016/j.biopha.2018.05.045. Epub 2018 May 14. Review.

PMID:
29772444
46.

IL-6 Drives Neutrophil-Mediated Pulmonary Inflammation Associated with Bacteremia in Murine Models of Colitis.

Mateer SW, Mathe A, Bruce J, Liu G, Maltby S, Fricker M, Goggins BJ, Tay HL, Marks E, Burns G, Kim RY, Minahan K, Walker MM, Callister RC, Foster PS, Horvat JC, Hansbro PM, Keely S.

Am J Pathol. 2018 Jul;188(7):1625-1639. doi: 10.1016/j.ajpath.2018.03.016. Epub 2018 Apr 22.

PMID:
29684360
47.

Activation of the Absent in Melanoma 2 Inflammasome in Peripheral Blood Mononuclear Cells From Idiopathic Pulmonary Fibrosis Patients Leads to the Release of Pro-Fibrotic Mediators.

Terlizzi M, Molino A, Colarusso C, Donovan C, Imitazione P, Somma P, Aquino RP, Hansbro PM, Pinto A, Sorrentino R.

Front Immunol. 2018 Apr 5;9:670. doi: 10.3389/fimmu.2018.00670. eCollection 2018.

48.

Immunological axis of curcumin-loaded vesicular drug delivery systems.

Chellappan DK, Ng ZY, Wong JY, Hsu A, Wark P, Hansbro N, Taylor J, Panneerselvam J, Madheswaran T, Gupta G, Bebawy M, Hansbro PM, Dua K.

Future Med Chem. 2018 Apr 1;10(8):839-844. doi: 10.4155/fmc-2017-0245. Epub 2018 Apr 5.

PMID:
29620416
49.

Nanoparticles in Cancer Treatment: Opportunities and Obstacles.

Awasthi R, Roseblade A, Hansbro PM, Rathbone MJ, Dua K, Bebawy M.

Curr Drug Targets. 2018;19(14):1696-1709. doi: 10.2174/1389450119666180326122831.

PMID:
29577855
50.

Novel drug delivery approaches in treating pulmonary fibrosis.

Dua K, Awasthi R, Madan JR, Chellappan DK, Nalluri BN, Gupta G, Bebawy M, Hansbro PM.

Panminerva Med. 2018 Dec;60(4):238-240. doi: 10.23736/S0031-0808.18.03428-6. Epub 2018 Feb 26. No abstract available.

PMID:
29480673

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