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Items: 1 to 50 of 82

1.

Assessment of a Urinary Kidney MicroRNA Panel as Potential Nephron Segment-Specific Biomarkers of Subacute Renal Toxicity in Preclinical Rat Models.

Glineur SF, Hanon E, Dremier S, Snelling S, Berteau C, De Ron P, Nogueira da Costa A.

Toxicol Sci. 2018 Dec 1;166(2):409-419. doi: 10.1093/toxsci/kfy213.

PMID:
30169741
2.

Short-term and mid-term solutions for influenza vaccines.

Hanon E, Van der Most R, Del Giudice G, Rappuoli R.

Lancet Infect Dis. 2018 Aug;18(8):832-833. doi: 10.1016/S1473-3099(18)30404-3. No abstract available.

PMID:
30064669
3.

In vitro screening of cell bioenergetics to assess mitochondrial dysfunction in drug development.

Tilmant K, Gerets H, De Ron P, Hanon E, Bento-Pereira C, Atienzar FA.

Toxicol In Vitro. 2018 Oct;52:374-383. doi: 10.1016/j.tiv.2018.07.012. Epub 2018 Jul 17.

PMID:
30030051
4.

Sustainable vaccine development: a vaccine manufacturer's perspective.

Rappuoli R, Hanon E.

Curr Opin Immunol. 2018 Aug;53:111-118. doi: 10.1016/j.coi.2018.04.019. Epub 2018 May 8. Review.

5.

Intrinsic Inflammation Is a Potential Anti-Epileptogenic Target in the Organotypic Hippocampal Slice Model.

Chong SA, Balosso S, Vandenplas C, Szczesny G, Hanon E, Claes K, Van Damme X, Danis B, Van Eyll J, Wolff C, Vezzani A, Kaminski RM, Niespodziany I.

Neurotherapeutics. 2018 Apr;15(2):470-488. doi: 10.1007/s13311-018-0607-6.

6.

Towards an evidence based approach for the development of adjuvanted vaccines.

O'Hagan DT, Friedland LR, Hanon E, Didierlaurent AM.

Curr Opin Immunol. 2017 Aug;47:93-102. doi: 10.1016/j.coi.2017.07.010. Epub 2017 Jul 26. Review.

7.

Differential expression of miR-184 in temporal lobe epilepsy patients with and without hippocampal sclerosis - Influence on microglial function.

Danis B, van Rikxoort M, Kretschmann A, Zhang J, Godard P, Andonovic L, Siegel F, Niehusmann P, Hanon E, Delev D, von Lehe M, Kaminski RM, Pfeifer A, Foerch P.

Sci Rep. 2016 Sep 26;6:33943. doi: 10.1038/srep33943.

8.

Pramipexole induced place preference after L-dopa therapy and nigral dopaminergic loss: linking behavior to transcriptional modifications.

Loiodice S, Winlow P, Dremier S, Hanon E, Dardou D, Ouachikh O, Hafidi A, da Costa AN, Durif F.

Psychopharmacology (Berl). 2017 Jan;234(1):15-27. doi: 10.1007/s00213-016-4430-7. Epub 2016 Sep 10.

PMID:
27614895
9.

Using Bayesian analysis in repeated preclinical in vivo studies for a more effective use of animals.

Walley R, Sherington J, Rastrick J, Detrait E, Hanon E, Watt G.

Pharm Stat. 2016 May;15(3):277-85. doi: 10.1002/pst.1748. Epub 2016 Mar 29.

PMID:
27028721
10.

Correlating behaviour and gene expression endpoints in the dopaminergic system after modafinil administration in mouse.

De Ron P, Dremier S, Winlow P, Jenkins A, Hanon E, Nogueira da Costa A.

Eur Neuropsychopharmacol. 2016 Apr;26(4):729-40. doi: 10.1016/j.euroneuro.2016.01.010. Epub 2016 Feb 1.

PMID:
26875113
11.

Paving the Route to Plasma miR-208a-3p as an Acute Cardiac Injury Biomarker: Preclinical Rat Data Supports Its Use in Drug Safety Assessment.

Glineur SF, De Ron P, Hanon E, Valentin JP, Dremier S, Nogueira da Costa A.

Toxicol Sci. 2016 Jan;149(1):89-97. doi: 10.1093/toxsci/kfv222. Epub 2015 Oct 9.

PMID:
26454886
12.

Optimization and pharmacological validation of a set-shifting procedure for assessing executive function in rats.

Troudet R, Detrait E, Hanon E, Lamberty Y.

J Neurosci Methods. 2016 Aug 1;268:182-8. doi: 10.1016/j.jneumeth.2015.08.012. Epub 2015 Aug 19.

PMID:
26296285
13.

Brivaracetam differentially affects voltage-gated sodium currents without impairing sustained repetitive firing in neurons.

Niespodziany I, André VM, Leclère N, Hanon E, Ghisdal P, Wolff C.

CNS Neurosci Ther. 2015 Mar;21(3):241-51. doi: 10.1111/cns.12347. Epub 2014 Dec 1.

14.

Retraction of the letter: "Comment on 'CD4⁺ T cell autoimmunity to hypocretin/orexin and cross-reactivity to a 2009 H1N1 influenza A epitope in narcolepsy' ".

van der Most R, Wettendorff M, Innis B, Hanon E.

Sci Transl Med. 2014 Sep 24;6(255):255rt2. doi: 10.1126/scitranslmed.3010397. No abstract available.

PMID:
25253677
15.

Seeking help: B cells adapting to flu variability.

van der Most RG, Roman FP, Innis B, Hanon E, Vaughn DW, Gillard P, Walravens K, Wettendorff M.

Sci Transl Med. 2014 Jul 23;6(246):246ps8. doi: 10.1126/scitranslmed.3008409.

PMID:
25101885
16.

Different microRNA profiles in chronic epilepsy versus acute seizure mouse models.

Kretschmann A, Danis B, Andonovic L, Abnaof K, van Rikxoort M, Siegel F, Mazzuferi M, Godard P, Hanon E, Fröhlich H, Kaminski RM, Foerch P, Pfeifer A.

J Mol Neurosci. 2015 Feb;55(2):466-79. doi: 10.1007/s12031-014-0368-6. Epub 2014 Jul 31.

17.
18.

Lack of synaptic vesicle protein SV2B protects against amyloid-β₂₅₋₃₅-induced oxidative stress, cholinergic deficit and cognitive impairment in mice.

Detrait E, Maurice T, Hanon E, Leclercq K, Lamberty Y.

Behav Brain Res. 2014 Sep 1;271:277-85. doi: 10.1016/j.bbr.2014.06.013. Epub 2014 Jun 14.

PMID:
24937053
19.

Narcolepsy and A(H1N1)pdm09 vaccination: shaping the research on the observed signal.

van der Most R, Van Mechelen M, Destexhe E, Wettendorff M, Hanon E.

Hum Vaccin Immunother. 2014;10(3):572-6. Epub 2013 Dec 16.

20.

Sampling and storage conditions influencing the measurement of parathyroid hormone in blood samples: a systematic review.

Hanon EA, Sturgeon CM, Lamb EJ.

Clin Chem Lab Med. 2013 Oct;51(10):1925-41. doi: 10.1515/cclm-2013-0315. Review.

PMID:
24072573
21.

Advantageous safety profile of a dual selective alpha(2C) agonist/alpha(2A) antagonist antinociceptive agent.

Delaunois A, De Ron P, Dedoncker P, Rosseels ML, Cornet M, Jnoff E, Hanon E, Guyaux M, Depelchin BO.

Fundam Clin Pharmacol. 2014 Aug;28(4):423-38. doi: 10.1111/fcp.12047. Epub 2013 Sep 11.

PMID:
24020399
22.

Determining the relative efficacy of positive allosteric modulators of the GABAA receptor: design of a screening approach.

Ghisdal P, Noel N, Pacico N, Martini M, Foerch P, Hanon E, Wolff C.

J Biomol Screen. 2014 Mar;19(3):462-7. doi: 10.1177/1087057113501555. Epub 2013 Aug 29.

PMID:
23989455
23.

Hydroxypropyl-β-cyclodextrin impacts renal and systemic hemodynamics in the anesthetized dog.

Rosseels ML, Delaunois AG, Hanon E, Guillaume PJ, Martin FD, van den Dobbelsteen DJ.

Regul Toxicol Pharmacol. 2013 Dec;67(3):351-9. doi: 10.1016/j.yrtph.2013.08.013. Epub 2013 Aug 23.

PMID:
23978386
24.

Long-term persistence of humoral and cellular immune responses induced by an AS03A-adjuvanted H1N1 2009 influenza vaccine: an open-label, randomized study in adults aged 18-60 years and older.

Van Damme P, Kafeja F, Bambure V, Hanon E, Moris P, Roman F, Gillard P.

Hum Vaccin Immunother. 2013 Jul;9(7):1512-22. doi: 10.4161/hv.24504. Epub 2013 Apr 9.

PMID:
23571166
25.

Photoperiodic variation in CD45-positive cells and cell proliferation in the mediobasal hypothalamus of the Soay sheep.

Hazlerigg DG, Wyse CA, Dardente H, Hanon EA, Lincoln GA.

Chronobiol Int. 2013 May;30(4):548-58. doi: 10.3109/07420528.2012.754450. Epub 2013 Feb 20.

PMID:
23425358
26.

Circannual variation in thyroid hormone deiodinases in a short-day breeder.

Sáenz de Miera C, Hanon EA, Dardente H, Birnie M, Simonneaux V, Lincoln GA, Hazlerigg DG.

J Neuroendocrinol. 2013 Apr;25(4):412-21. doi: 10.1111/jne.12013.

PMID:
23282080
27.

Analysis of the diastereoisomers of alliin by HPLC.

Dethier B, Laloux M, Hanon E, Nott K, Heuskin S, Wathelet JP.

Talanta. 2012 Nov 15;101:447-52. doi: 10.1016/j.talanta.2012.09.058. Epub 2012 Oct 5.

PMID:
23158347
28.

The use of real-time cell analyzer technology in drug discovery: defining optimal cell culture conditions and assay reproducibility with different adherent cellular models.

Atienzar FA, Tilmant K, Gerets HH, Toussaint G, Speeckaert S, Hanon E, Depelchin O, Dhalluin S.

J Biomol Screen. 2011 Jul;16(6):575-87. doi: 10.1177/1087057111402825. Epub 2011 Apr 25.

PMID:
21518825
29.

Comparison of a genomic and a multiplex cell imaging approach for the detection of phospholipidosis.

Tilmant K, Gerets HH, Dhalluin S, Hanon E, Depelchin O, Cossu-Leguille C, Vasseur P, Atienzar FA.

Toxicol In Vitro. 2011 Oct;25(7):1414-24. doi: 10.1016/j.tiv.2011.04.010. Epub 2011 Apr 15.

PMID:
21515356
30.

Will isomalto-oligosaccharides, a well-established functional food in Asia, break through the European and American market? The status of knowledge on these prebiotics.

Goffin D, Delzenne N, Blecker C, Hanon E, Deroanne C, Paquot M.

Crit Rev Food Sci Nutr. 2011 May;51(5):394-409. doi: 10.1080/10408391003628955. Review.

PMID:
21491266
31.

Effect on cellular and humoral immune responses of the AS03 adjuvant system in an A/H1N1/2009 influenza virus vaccine administered to adults during two randomized controlled trials.

Roman F, Clément F, Dewé W, Walravens K, Maes C, Willekens J, De Boever F, Hanon E, Leroux-Roels G.

Clin Vaccine Immunol. 2011 May;18(5):835-43. doi: 10.1128/CVI.00480-10. Epub 2011 Mar 30.

32.

Pandemic H1N1 vaccine requires the use of an adjuvant to protect against challenge in naïve ferrets.

Baras B, de Waal L, Stittelaar KJ, Jacob V, Giannini S, Kroeze EJ, van den Brand JM, van Amerongen G, Simon JH, Hanon E, Mossman SP, Osterhaus AD.

Vaccine. 2011 Mar 3;29(11):2120-6. doi: 10.1016/j.vaccine.2010.12.125. Epub 2011 Jan 14.

PMID:
21238573
33.

Longevity of the protective immune response induced after vaccination with one or two doses of AS03A-adjuvanted split H5N1 vaccine in ferrets.

Baras B, Stittelaar KJ, Kuiken T, Jacob V, Bernhard R, Giannini S, de Waal L, van Amerongen G, Simon JH, Osterhaus AD, Hanon E, Mossman SP.

Vaccine. 2011 Mar 3;29(11):2092-9. doi: 10.1016/j.vaccine.2010.12.128. Epub 2011 Jan 13.

PMID:
21237275
34.

H5N1 influenza vaccine formulated with AS03 A induces strong cross-reactive and polyfunctional CD4 T-cell responses.

Moris P, van der Most R, Leroux-Roels I, Clement F, Dramé M, Hanon E, Leroux-Roels GG, Van Mechelen M.

J Clin Immunol. 2011 Jun;31(3):443-54. doi: 10.1007/s10875-010-9490-6. Epub 2010 Dec 21.

35.

AS03(A)-Adjuvanted influenza A (H1N1) 2009 vaccine for adults up to 85 years of age.

Roman F, Vaman T, Kafeja F, Hanon E, Van Damme P.

Clin Infect Dis. 2010 Sep 15;51(6):668-77. doi: 10.1086/655830.

PMID:
20687838
36.

Brivaracetam does not alter spatial learning and memory in both normal and amygdala-kindled rats.

Detrait ER, Leclercq K, Löscher W, Potschka H, Niespodziany I, Hanon E, Kaminski RM, Matagne A, Lamberty Y.

Epilepsy Res. 2010 Sep;91(1):74-83. doi: 10.1016/j.eplepsyres.2010.06.014. Epub 2010 Aug 1.

PMID:
20678901
37.

Effect of photoperiod on the thyroid-stimulating hormone neuroendocrine system in the European hamster (Cricetus cricetus).

Hanon EA, Routledge K, Dardente H, Masson-Pévet M, Morgan PJ, Hazlerigg DG.

J Neuroendocrinol. 2010 Jan;22(1):51-5. doi: 10.1111/j.1365-2826.2009.01937.x. Epub 2009 Nov 14.

PMID:
19912472
38.

Priming with AS03 A-adjuvanted H5N1 influenza vaccine improves the kinetics, magnitude and durability of the immune response after a heterologous booster vaccination: an open non-randomised extension of a double-blind randomised primary study.

Leroux-Roels I, Roman F, Forgus S, Maes C, De Boever F, Dramé M, Gillard P, van der Most R, Van Mechelen M, Hanon E, Leroux-Roels G.

Vaccine. 2010 Jan 8;28(3):849-57. doi: 10.1016/j.vaccine.2009.10.017. Epub 2009 Oct 14.

PMID:
19835828
39.

Repeated assessment of cardiovascular and respiratory functions using combined telemetry and whole-body plethysmography in the rat.

Delaunois A, Dedoncker P, Hanon E, Guyaux M.

J Pharmacol Toxicol Methods. 2009 Sep-Oct;60(2):117-29. doi: 10.1016/j.vascn.2009.07.003. Epub 2009 Jul 17.

PMID:
19616108
40.

The inhibitory avoidance test optimized for discovery of cognitive enhancers.

Detrait ER, Hanon E, Dardenne B, Lamberty Y.

Behav Res Methods. 2009 Aug;41(3):805-11. doi: 10.3758/BRM.41.3.805.

PMID:
19587195
41.

Proepileptic phenotype of SV2A-deficient mice is associated with reduced anticonvulsant efficacy of levetiracetam.

Kaminski RM, Gillard M, Leclercq K, Hanon E, Lorent G, Dassesse D, Matagne A, Klitgaard H.

Epilepsia. 2009 Jul;50(7):1729-40. doi: 10.1111/j.1528-1167.2009.02089.x. Epub 2009 Apr 19.

42.

A vaccine manufacturer's approach to address medical needs related to seasonal and pandemic influenza viruses.

Baras B, Bouveret N, Devaster JM, Fries L, Gillard P, Sänger R, Hanon E.

Influenza Other Respir Viruses. 2008 Nov;2(6):251-60. doi: 10.1111/j.1750-2659.2008.00054.x. Review.

43.

Vaccination strategies against influenza.

Hanon E.

Bull Mem Acad R Med Belg. 2009;164(10):283-7.

PMID:
20669618
44.

Selection of cytotoxicity markers for the screening of new chemical entities in a pharmaceutical context: a preliminary study using a multiplexing approach.

Gerets HH, Hanon E, Cornet M, Dhalluin S, Depelchin O, Canning M, Atienzar FA.

Toxicol In Vitro. 2009 Mar;23(2):319-32. doi: 10.1016/j.tiv.2008.11.012. Epub 2008 Dec 10.

PMID:
19110050
45.

Ancestral TSH mechanism signals summer in a photoperiodic mammal.

Hanon EA, Lincoln GA, Fustin JM, Dardente H, Masson-Pévet M, Morgan PJ, Hazlerigg DG.

Curr Biol. 2008 Aug 5;18(15):1147-52. doi: 10.1016/j.cub.2008.06.076.

46.

Broad Clade 2 cross-reactive immunity induced by an adjuvanted clade 1 rH5N1 pandemic influenza vaccine.

Leroux-Roels I, Bernhard R, Gérard P, Dramé M, Hanon E, Leroux-Roels G.

PLoS One. 2008 Feb 27;3(2):e1665. doi: 10.1371/journal.pone.0001665.

47.

Vaccine adjuvant systems containing monophosphoryl lipid A and QS21 induce strong and persistent humoral and T cell responses against hepatitis B surface antigen in healthy adult volunteers.

Vandepapelière P, Horsmans Y, Moris P, Van Mechelen M, Janssens M, Koutsoukos M, Van Belle P, Clement F, Hanon E, Wettendorff M, Garçon N, Leroux-Roels G.

Vaccine. 2008 Mar 4;26(10):1375-86. doi: 10.1016/j.vaccine.2007.12.038. Epub 2008 Jan 14.

PMID:
18272264
48.

Enrichment of anhydrous milk fat in polyunsaturated fatty acid residues from linseed and rapeseed oils through enzymatic interesterification.

Aguedo M, Hanon E, Danthine S, Paquot M, Lognay G, Thomas A, Vandenbol M, Thonart P, Wathelet JP, Blecker C.

J Agric Food Chem. 2008 Mar 12;56(5):1757-65. doi: 10.1021/jf0722203. Epub 2008 Feb 14.

PMID:
18271538
49.

Cross-protection against lethal H5N1 challenge in ferrets with an adjuvanted pandemic influenza vaccine.

Baras B, Stittelaar KJ, Simon JH, Thoolen RJ, Mossman SP, Pistoor FH, van Amerongen G, Wettendorff MA, Hanon E, Osterhaus AD.

PLoS One. 2008 Jan 2;3(1):e1401. doi: 10.1371/journal.pone.0001401.

50.

Enhanced humoral and memory B cellular immunity using HPV16/18 L1 VLP vaccine formulated with the MPL/aluminium salt combination (AS04) compared to aluminium salt only.

Giannini SL, Hanon E, Moris P, Van Mechelen M, Morel S, Dessy F, Fourneau MA, Colau B, Suzich J, Losonksy G, Martin MT, Dubin G, Wettendorff MA.

Vaccine. 2006 Aug 14;24(33-34):5937-49. Epub 2006 Jun 19.

PMID:
16828940

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