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Items: 1 to 50 of 61

1.

Renal hemodynamics and fatty acid uptake: effects of obesity and weight loss.

Rebelos E, Dadson P, Oikonen V, Iida H, Hannukainen JC, Iozzo P, Ferrannini E, Nuutila P.

Am J Physiol Endocrinol Metab. 2019 Nov 1;317(5):E871-E878. doi: 10.1152/ajpendo.00135.2019. Epub 2019 Sep 24.

PMID:
31550182
2.

Exercise Training Modulates Gut Microbiota Profile and Improves Endotoxemia.

Motiani KK, Collado MC, Eskelinen JJ, Virtanen KA, Löyttyniemi E, Salminen S, Nuutila P, Kalliokoski KK, Hannukainen JC.

Med Sci Sports Exerc. 2020 Jan;52(1):94-104. doi: 10.1249/MSS.0000000000002112.

PMID:
31425383
3.

Exercise training alters lipoprotein particles independent of brown adipose tissue metabolic activity.

Motiani P, Teuho J, Saari T, Virtanen KA, Honkala SM, Middelbeek RJ, Goodyear LJ, Eskola O, Andersson J, Löyttyniemi E, Hannukainen JC, Nuutila P.

Obes Sci Pract. 2019 Apr 24;5(3):258-272. doi: 10.1002/osp4.330. eCollection 2019 Jun.

4.

TGF-β2 is an exercise-induced adipokine that regulates glucose and fatty acid metabolism.

Takahashi H, Alves CRR, Stanford KI, Middelbeek RJW, Pasquale Nigro, Ryan RE, Xue R, Sakaguchi M, Lynes MD, So K, Mul JD, Lee MY, Balan E, Pan H, Dreyfuss JM, Hirshman MF, Azhar M, Hannukainen JC, Nuutila P, Kalliokoski KK, Nielsen S, Pedersen BK, Kahn CR, Tseng YH, Goodyear LJ.

Nat Metab. 2019 Feb;1(2):291-303. doi: 10.1038/s42255-018-0030-7. Epub 2019 Feb 11.

5.

Effects of short-term sprint interval and moderate-intensity continuous training on liver fat content, lipoprotein profile, and substrate uptake: a randomized trial.

Motiani KK, Savolainen AM, Toivanen J, Eskelinen JJ, Yli-Karjanmaa M, Virtanen KA, Saunavaara V, Heiskanen MA, Parkkola R, Haaparanta-Solin M, Solin O, Savisto N, Löyttyniemi E, Knuuti J, Nuutila P, Kalliokoski KK, Hannukainen JC.

J Appl Physiol (1985). 2019 Jun 1;126(6):1756-1768. doi: 10.1152/japplphysiol.00900.2018. Epub 2019 Apr 18.

PMID:
30998125
6.

The SGLT2 Inhibitor Dapagliflozin Reduces Liver Fat but Does Not Affect Tissue Insulin Sensitivity: A Randomized, Double-Blind, Placebo-Controlled Study With 8-Week Treatment in Type 2 Diabetes Patients.

Latva-Rasku A, Honka MJ, Kullberg J, Mononen N, Lehtimäki T, Saltevo J, Kirjavainen AK, Saunavaara V, Iozzo P, Johansson L, Oscarsson J, Hannukainen JC, Nuutila P.

Diabetes Care. 2019 May;42(5):931-937. doi: 10.2337/dc18-1569. Epub 2019 Mar 18.

PMID:
30885955
7.

Intramyocellular lipid accumulation after sprint interval and moderate-intensity continuous training in healthy and diabetic subjects.

Sjöros T, Saunavaara V, Löyttyniemi E, Koivumäki M, Heinonen IHA, Eskelinen JJ, Virtanen KA, Hannukainen JC, Kalliokoski KK.

Physiol Rep. 2019 Feb;7(3):e13980. doi: 10.14814/phy2.13980.

8.

Effects of bariatric surgery on retinal microvascular architecture in obese patients.

Viljanen A, Soinio M, Cheung CY, Hannukainen JC, Karlsson HK, Wong TY, Hughes AD, Salminen P, Nuutila P, Vesti E, Tapp RJ.

Int J Obes (Lond). 2019 Sep;43(9):1675-1680. doi: 10.1038/s41366-018-0242-7. Epub 2018 Dec 5.

PMID:
30518825
9.

Comment on 'Exercise training decreases pancreatic fat content and improves beta cell function regardless of baseline glucose tolerance: a randomised controlled trial'. Reply to Amini P and Moharamzadeh S [letter].

Heiskanen MA, Motiani KK, Mari A, Eskelinen JJ, Virtanen KA, Löyttyniemi E, Kalliokoski KK, Hannukainen JC.

Diabetologia. 2019 Jan;62(1):204-206. doi: 10.1007/s00125-018-4762-4. Epub 2018 Nov 8. No abstract available.

PMID:
30406809
10.

Physical Activity Associates with Muscle Insulin Sensitivity Postbariatric Surgery.

Savolainen AM, Karmi A, Immonen H, Soinio M, Saunavaara V, Pham T, Salminen P, Helmiö M, Ovaska J, Löyttyniemi E, Heiskanen MA, Lehtimäki T, Mari A, Nuutila P, Hannukainen JC.

Med Sci Sports Exerc. 2019 Feb;51(2):278-287. doi: 10.1249/MSS.0000000000001778.

11.

The effect of bariatric surgery on intraocular pressure.

Viljanen A, Hannukainen JC, Soinio M, Karlsson HK, Salminen P, Nuutila P, Vesti E.

Acta Ophthalmol. 2018 Dec;96(8):849-852. doi: 10.1111/aos.13826. Epub 2018 Sep 20.

12.

Brain glucose uptake is associated with endogenous glucose production in obese patients before and after bariatric surgery and predicts metabolic outcome at follow-up.

Rebelos E, Immonen H, Bucci M, Hannukainen JC, Nummenmaa L, Honka MJ, Soinio M, Salminen P, Ferrannini E, Iozzo P, Nuutila P.

Diabetes Obes Metab. 2019 Feb;21(2):218-226. doi: 10.1111/dom.13501. Epub 2018 Sep 16.

13.

Exercise training decreases pancreatic fat content and improves beta cell function regardless of baseline glucose tolerance: a randomised controlled trial.

Heiskanen MA, Motiani KK, Mari A, Saunavaara V, Eskelinen JJ, Virtanen KA, Koivumäki M, Löyttyniemi E, Nuutila P, Kalliokoski KK, Hannukainen JC.

Diabetologia. 2018 Aug;61(8):1817-1828. doi: 10.1007/s00125-018-4627-x. Epub 2018 May 2.

14.

Insulin-stimulated glucose uptake in skeletal muscle, adipose tissue and liver: a positron emission tomography study.

Honka MJ, Latva-Rasku A, Bucci M, Virtanen KA, Hannukainen JC, Kalliokoski KK, Nuutila P.

Eur J Endocrinol. 2018 May;178(5):523-531. doi: 10.1530/EJE-17-0882. Epub 2018 Mar 13.

15.

Brown adipose tissue lipid metabolism in morbid obesity: Effect of bariatric surgery-induced weight loss.

Dadson P, Hannukainen JC, Din MU, Lahesmaa M, Kalliokoski KK, Iozzo P, Pihlajamäki J, Karlsson HK, Parkkola R, Salminen P, Virtanen KA, Nuutila P.

Diabetes Obes Metab. 2018 May;20(5):1280-1288. doi: 10.1111/dom.13233. Epub 2018 Feb 22.

PMID:
29377423
16.

Reversibility of myocardial metabolism and remodelling in morbidly obese patients 6 months after bariatric surgery.

Hannukainen JC, Lautamäki R, Pärkkä J, Strandberg M, Saunavaara V, Hurme S, Soinio M, Dadson P, Virtanen KA, Grönroos T, Forsback S, Salminen P, Iozzo P, Nuutila P.

Diabetes Obes Metab. 2018 Apr;20(4):963-973. doi: 10.1111/dom.13183. Epub 2018 Jan 17.

17.

Increased Liver Fatty Acid Uptake Is Partly Reversed and Liver Fat Content Normalized After Bariatric Surgery.

Immonen H, Hannukainen JC, Kudomi N, Pihlajamäki J, Saunavaara V, Laine J, Salminen P, Lehtimäki T, Pham T, Iozzo P, Nuutila P.

Diabetes Care. 2018 Feb;41(2):368-371. doi: 10.2337/dc17-0738. Epub 2017 Nov 20.

PMID:
29158250
18.

Short-term interval training alters brain glucose metabolism in subjects with insulin resistance.

Honkala SM, Johansson J, Motiani KK, Eskelinen JJ, Virtanen KA, Löyttyniemi E, Knuuti J, Nuutila P, Kalliokoski KK, Hannukainen JC.

J Cereb Blood Flow Metab. 2018 Oct;38(10):1828-1838. doi: 10.1177/0271678X17734998. Epub 2017 Sep 29. Erratum in: J Cereb Blood Flow Metab. 2018 Jan 1;:271678X18766840.

19.

Sprint interval training decreases left-ventricular glucose uptake compared to moderate-intensity continuous training in subjects with type 2 diabetes or prediabetes.

Heiskanen MA, Sjöros TJ, Heinonen IHA, Löyttyniemi E, Koivumäki M, Motiani KK, Eskelinen JJ, Virtanen KA, Knuuti J, Hannukainen JC, Kalliokoski KK.

Sci Rep. 2017 Sep 5;7(1):10531. doi: 10.1038/s41598-017-10931-9.

20.

Affective Adaptation to Repeated SIT and MICT Protocols in Insulin-Resistant Subjects.

Saanijoki T, Nummenmaa L, Koivumäki M, Löyttyniemi E, Kalliokoski KK, Hannukainen JC.

Med Sci Sports Exerc. 2018 Jan;50(1):18-27. doi: 10.1249/MSS.0000000000001415.

PMID:
28857909
21.

Erratum. Weight Loss After Bariatric Surgery Reverses Insulin-Induced Increases in Brain Glucose Metabolism of the Morbidly Obese. Diabetes 2013;62:2747-2751.

Tuulari JJ, Karlsson HK, Hirvonen J, Hannukainen JC, Bucci M, Helmiö M, Ovaska J, Soinio M, Salminen P, Savisto N, Nummenmaa L, Nuutila P.

Diabetes. 2017 Oct;66(10):2724. doi: 10.2337/db17-er10a. Epub 2017 Aug 1. No abstract available.

22.

Exercise Training Reduces Intrathoracic Fat Regardless of Defective Glucose Tolerance.

Honkala SM, Motiani KK, Eskelinen JJ, Savolainen A, Saunavaara V, Virtanen KA, Löyttyniemi E, Kapanen J, Knuuti J, Kalliokoski KK, Hannukainen JC.

Med Sci Sports Exerc. 2017 Jul;49(7):1313-1322. doi: 10.1249/MSS.0000000000001232.

23.

Fatty acid uptake and blood flow in adipose tissue compartments of morbidly obese subjects with or without type 2 diabetes: effects of bariatric surgery.

Dadson P, Ferrannini E, Landini L, Hannukainen JC, Kalliokoski KK, Vaittinen M, Honka H, Karlsson HK, Tuulari JJ, Soinio M, Salminen P, Parkkola R, Pihlajamäki J, Iozzo P, Nuutila P.

Am J Physiol Endocrinol Metab. 2017 Aug 1;313(2):E175-E182. doi: 10.1152/ajpendo.00044.2017. Epub 2017 Apr 11.

24.

Decreased insulin-stimulated brown adipose tissue glucose uptake after short-term exercise training in healthy middle-aged men.

Motiani P, Virtanen KA, Motiani KK, Eskelinen JJ, Middelbeek RJ, Goodyear LJ, Savolainen AM, Kemppainen J, Jensen J, Din MU, Saunavaara V, Parkkola R, Löyttyniemi E, Knuuti J, Nuutila P, Kalliokoski KK, Hannukainen JC.

Diabetes Obes Metab. 2017 Oct;19(10):1379-1388. doi: 10.1111/dom.12947. Epub 2017 Jul 6.

25.

Increased insulin-stimulated glucose uptake in both leg and arm muscles after sprint interval and moderate-intensity training in subjects with type 2 diabetes or prediabetes.

Sjöros TJ, Heiskanen MA, Motiani KK, Löyttyniemi E, Eskelinen JJ, Virtanen KA, Savisto NJ, Solin O, Hannukainen JC, Kalliokoski KK.

Scand J Med Sci Sports. 2018 Jan;28(1):77-87. doi: 10.1111/sms.12875. Epub 2017 Apr 10.

PMID:
28295686
26.

Two weeks of moderate-intensity continuous training, but not high-intensity interval training, increases insulin-stimulated intestinal glucose uptake.

Motiani KK, Savolainen AM, Eskelinen JJ, Toivanen J, Ishizu T, Yli-Karjanmaa M, Virtanen KA, Parkkola R, Kapanen J, Grönroos TJ, Haaparanta-Solin M, Solin O, Savisto N, Ahotupa M, Löyttyniemi E, Knuuti J, Nuutila P, Kalliokoski KK, Hannukainen JC.

J Appl Physiol (1985). 2017 May 1;122(5):1188-1197. doi: 10.1152/japplphysiol.00431.2016. Epub 2017 Feb 9.

27.

Changes in bone metabolism after bariatric surgery by gastric bypass or sleeve gastrectomy.

Ivaska KK, Huovinen V, Soinio M, Hannukainen JC, Saunavaara V, Salminen P, Helmiö M, Parkkola R, Nuutila P, Kiviranta R.

Bone. 2017 Feb;95:47-54. doi: 10.1016/j.bone.2016.11.001. Epub 2016 Nov 3.

PMID:
27818311
28.

Left ventricular vascular and metabolic adaptations to high-intensity interval and moderate intensity continuous training: a randomized trial in healthy middle-aged men.

Eskelinen JJ, Heinonen I, Löyttyniemi E, Hakala J, Heiskanen MA, Motiani KK, Virtanen K, Pärkkä JP, Knuuti J, Hannukainen JC, Kalliokoski KK.

J Physiol. 2016 Dec 1;594(23):7127-7140. doi: 10.1113/JP273089. Epub 2016 Sep 27.

29.

Right ventricular metabolic adaptations to high-intensity interval and moderate-intensity continuous training in healthy middle-aged men.

Heiskanen MA, Leskinen T, Heinonen IH, Löyttyniemi E, Eskelinen JJ, Virtanen K, Hannukainen JC, Kalliokoski KK.

Am J Physiol Heart Circ Physiol. 2016 Sep 1;311(3):H667-75. doi: 10.1152/ajpheart.00399.2016. Epub 2016 Jul 22.

30.

Influence of triple disease modifying anti-rheumatic drug therapy on carotid artery inflammation in drug-naive patients with recent onset of rheumatoid arthritis.

Haavisto M, Saraste A, Pirilä L, Hannukainen JC, Kalliokoski KK, Kirjavainen A, Kemppainen J, Möttönen T, Knuuti J, Yli-Kerttula T, Roivainen A.

Rheumatology (Oxford). 2016 Oct;55(10):1777-85. doi: 10.1093/rheumatology/kew240. Epub 2016 Jun 21.

PMID:
27330160
31.

Home-Based Exercise Training Improves Left Ventricle Diastolic Function in Survivors of Childhood ALL: A Tissue Doppler and Velocity Vector Imaging Study.

Järvelä LS, Saraste M, Niinikoski H, Hannukainen JC, Heinonen OJ, Lähteenmäki PM, Arola M, Kemppainen J.

Pediatr Blood Cancer. 2016 Sep;63(9):1629-35. doi: 10.1002/pbc.26051. Epub 2016 May 16.

PMID:
27198652
32.

Elevated Glucose Oxidation, Reduced Insulin Secretion, and a Fatty Heart May Be Protective Adaptions in Ischemic CAD.

Hannukainen JC, Lautamäki R, Mari A, Pärkkä JP, Bucci M, Guzzardi MA, Kajander S, Tuokkola T, Knuuti J, Iozzo P.

J Clin Endocrinol Metab. 2016 Jul;101(7):2701-10. doi: 10.1210/jc.2015-4091. Epub 2016 Apr 5.

33.

Different Predictors of Right and Left Ventricular Metabolism in Healthy Middle-Aged Men.

Heiskanen MA, Leskinen T, Eskelinen JJ, Heinonen IH, Löyttyniemi E, Virtanen K, Pärkkä JP, Hannukainen JC, Kalliokoski KK.

Front Physiol. 2015 Dec 21;6:389. doi: 10.3389/fphys.2015.00389. eCollection 2015.

34.

Effect of Bariatric Surgery on Adipose Tissue Glucose Metabolism in Different Depots in Patients With or Without Type 2 Diabetes.

Dadson P, Landini L, Helmiö M, Hannukainen JC, Immonen H, Honka MJ, Bucci M, Savisto N, Soinio M, Salminen P, Parkkola R, Pihlajamäki J, Iozzo P, Ferrannini E, Nuutila P.

Diabetes Care. 2016 Feb;39(2):292-9. doi: 10.2337/dc15-1447. Epub 2015 Dec 17.

PMID:
26681717
35.

ADIPOSITY-RELATED CANCER AND FUNCTIONAL IMAGING OF BROWN ADIPOSE TISSUE.

Santhanam P, Solnes L, Hannukainen JC, Taïeb D.

Endocr Pract. 2015 Nov;21(11):1282-90. doi: 10.4158/EP15870.RA. Epub 2015 Aug 17. Review.

PMID:
26280202
36.

Autonomic Function Predicts Fitness Response to Short-Term High-Intensity Interval Training.

Kiviniemi AM, Tulppo MP, Eskelinen JJ, Savolainen AM, Kapanen J, Heinonen IH, Hautala AJ, Hannukainen JC, Kalliokoski KK.

Int J Sports Med. 2015 Nov;36(11):915-21. doi: 10.1055/s-0035-1549854. Epub 2015 Jul 3.

PMID:
26140689
37.

Affective Responses to Repeated Sessions of High-Intensity Interval Training.

Saanijoki T, Nummenmaa L, Eskelinen JJ, Savolainen AM, Vahlberg T, Kalliokoski KK, Hannukainen JC.

Med Sci Sports Exerc. 2015 Dec;47(12):2604-11. doi: 10.1249/MSS.0000000000000721.

PMID:
26110694
38.

Muscle-specific glucose and free fatty acid uptake after sprint interval and moderate-intensity training in healthy middle-aged men.

Eskelinen JJ, Heinonen I, Löyttyniemi E, Saunavaara V, Kirjavainen A, Virtanen KA, Hannukainen JC, Kalliokoski KK.

J Appl Physiol (1985). 2015 May 1;118(9):1172-80. doi: 10.1152/japplphysiol.01122.2014. Epub 2015 Mar 12. Erratum in: J Appl Physiol (1985). 2016 Mar 15;120(6):721-2.

39.

The effects of bariatric surgery on pancreatic lipid metabolism and blood flow.

Honka H, Koffert J, Hannukainen JC, Tuulari JJ, Karlsson HK, Immonen H, Oikonen V, Tolvanen T, Soinio M, Salminen P, Kudomi N, Mari A, Iozzo P, Nuutila P.

J Clin Endocrinol Metab. 2015 May;100(5):2015-23. doi: 10.1210/jc.2014-4236. Epub 2015 Mar 3.

PMID:
25734253
40.

Obesity-associated intestinal insulin resistance is ameliorated after bariatric surgery.

Mäkinen J, Hannukainen JC, Karmi A, Immonen HM, Soinio M, Nelimarkka L, Savisto N, Helmiö M, Ovaska J, Salminen P, Iozzo P, Nuutila P.

Diabetologia. 2015 May;58(5):1055-62. doi: 10.1007/s00125-015-3501-3. Epub 2015 Jan 29.

41.

Organ-specific physiological responses to acute physical exercise and long-term training in humans.

Heinonen I, Kalliokoski KK, Hannukainen JC, Duncker DJ, Nuutila P, Knuuti J.

Physiology (Bethesda). 2014 Nov;29(6):421-36. doi: 10.1152/physiol.00067.2013. Review.

42.

Enhanced fatty acid uptake in visceral adipose tissue is not reversed by weight loss in obese individuals with the metabolic syndrome.

Bucci M, Karmi AC, Iozzo P, Fielding BA, Viljanen A, Badeau RM, Borra R, Saunavaara V, Pham T, Hannukainen JC, Kalliokoski K, Haaparanta-Solin M, Viljanen T, Parkkola R, Frayn KN, Nuutila P.

Diabetologia. 2015 Jan;58(1):158-64. doi: 10.1007/s00125-014-3402-x. Epub 2014 Oct 21.

PMID:
25331375
43.

Imaging of Organ Metabolism in Obesity and Diabetes: Treatment Perspectives.

Hannukainen JC, Guzzardi MA, Virtanen KA, Sanguinetti E, Nuutila P, Iozzo P.

Curr Pharm Des. 2014;20(39):6126-49. Review.

PMID:
24745922
44.

Cardiac autonomic function and high-intensity interval training in middle-age men.

Kiviniemi AM, Tulppo MP, Eskelinen JJ, Savolainen AM, Kapanen J, Heinonen IH, Huikuri HV, Hannukainen JC, Kalliokoski KK.

Med Sci Sports Exerc. 2014 Oct;46(10):1960-7. doi: 10.1249/MSS.0000000000000307.

PMID:
24561814
45.

Pancreatic metabolism, blood flow, and β-cell function in obese humans.

Honka H, Hannukainen JC, Tarkia M, Karlsson H, Saunavaara V, Salminen P, Soinio M, Mikkola K, Kudomi N, Oikonen V, Haaparanta-Solin M, Roivainen A, Parkkola R, Iozzo P, Nuutila P.

J Clin Endocrinol Metab. 2014 Jun;99(6):E981-90. doi: 10.1210/jc.2013-4369. Epub 2014 Feb 14.

PMID:
24527718
46.

Hyperthyroidism increases brown fat metabolism in humans.

Lahesmaa M, Orava J, Schalin-Jäntti C, Soinio M, Hannukainen JC, Noponen T, Kirjavainen A, Iida H, Kudomi N, Enerbäck S, Virtanen KA, Nuutila P.

J Clin Endocrinol Metab. 2014 Jan;99(1):E28-35. doi: 10.1210/jc.2013-2312. Epub 2013 Dec 20.

PMID:
24152690
47.

Effect of bariatric surgery on liver glucose metabolism in morbidly obese diabetic and non-diabetic patients.

Immonen H, Hannukainen JC, Iozzo P, Soinio M, Salminen P, Saunavaara V, Borra R, Parkkola R, Mari A, Lehtimäki T, Pham T, Laine J, Kärjä V, Pihlajamäki J, Nelimarkka L, Nuutila P.

J Hepatol. 2014 Feb;60(2):377-83. doi: 10.1016/j.jhep.2013.09.012. Epub 2013 Sep 20.

PMID:
24060855
48.

Measurement of brown adipose tissue mass using a novel dual-echo magnetic resonance imaging approach: a validation study.

Holstila M, Virtanen KA, Grönroos TJ, Laine J, Lepomäki V, Saunavaara J, Lisinen I, Komu M, Hannukainen JC, Nuutila P, Parkkola R, Borra RJ.

Metabolism. 2013 Aug;62(8):1189-98. doi: 10.1016/j.metabol.2013.03.002. Epub 2013 Apr 13.

PMID:
23587549
49.

Obesity is associated with white matter atrophy: a combined diffusion tensor imaging and voxel-based morphometric study.

Karlsson HK, Tuulari JJ, Hirvonen J, Lepomäki V, Parkkola R, Hiltunen J, Hannukainen JC, Soinio M, Pham T, Salminen P, Nuutila P, Nummenmaa L.

Obesity (Silver Spring). 2013 Dec;21(12):2530-7. doi: 10.1002/oby.20386. Epub 2013 Jun 11.

50.

Weight loss after bariatric surgery reverses insulin-induced increases in brain glucose metabolism of the morbidly obese.

Tuulari JJ, Karlsson HK, Hirvonen J, Hannukainen JC, Bucci M, Helmiö M, Ovaska J, Soinio M, Salminen P, Savisto N, Nummenmaa L, Nuutila P.

Diabetes. 2013 Aug;62(8):2747-51. doi: 10.2337/db12-1460. Epub 2013 Mar 14. Erratum in: Diabetes. 2017 Oct;66(10 ):2724.

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