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Items: 48

1.

Transcriptional Activation of Inflammatory Genes: Mechanistic Insight into Selectivity and Diversity.

Ahmed AU, Williams BR, Hannigan GE.

Biomolecules. 2015 Nov 11;5(4):3087-111. doi: 10.3390/biom5043087. Review.

2.

Integrin-linked kinase modulates lipopolysaccharide- and Helicobacter pylori-induced nuclear factor κB-activated tumor necrosis factor-α production via regulation of p65 serine 536 phosphorylation.

Ahmed AU, Sarvestani ST, Gantier MP, Williams BR, Hannigan GE.

J Biol Chem. 2014 Oct 3;289(40):27776-93. doi: 10.1074/jbc.M114.574541. Epub 2014 Aug 6.

3.

Integrin-linked kinase in ciliary Hedgehog signaling.

Hannigan GE.

Cell Cycle. 2014;13(6):871-2. doi: 10.4161/cc.28188. Epub 2014 Feb 11. No abstract available.

4.

Serum integrin-linked kinase (sILK) concentration and survival in non-small cell lung cancer: a pilot study.

Posch F, Setinek U, Flores RM, Bernhard D, Hannigan GE, Mueller MR, Watzka SB.

Clin Transl Oncol. 2014 May;16(5):455-62. doi: 10.1007/s12094-013-1101-6. Epub 2013 Aug 27.

PMID:
23979911
5.

Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling.

Barakat B, Yu L, Lo C, Vu D, De Luca E, Cain JE, Martelotto LG, Dedhar S, Sadler AJ, Wang D, Watkins DN, Hannigan GE.

EMBO Rep. 2013 Sep;14(9):837-44. doi: 10.1038/embor.2013.110. Epub 2013 Jul 23. Erratum in: EMBO Rep. 2013 Oct;14(10):945. Martellotto, Luciano G [corrected to Martelotto, Luciano G].

6.

Selective regulation of p38β protein and signaling by integrin-linked kinase mediates bladder cancer cell migration.

Yu L, Yuan X, Wang D, Barakat B, Williams ED, Hannigan GE.

Oncogene. 2014 Feb 6;33(6):690-701. doi: 10.1038/onc.2013.20. Epub 2013 Feb 25.

PMID:
23435415
7.

Serum concentration of integrin-linked kinase in malignant pleural mesothelioma and after asbestos exposure.

Watzka SB, Posch F, Pass HI, Flores RM, Hannigan GE, Bernhard D, Weber M, Mueller MR.

Eur J Cardiothorac Surg. 2013 May;43(5):940-5. doi: 10.1093/ejcts/ezs521. Epub 2012 Oct 7.

8.

Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer.

O'Toole SA, Machalek DA, Shearer RF, Millar EK, Nair R, Schofield P, McLeod D, Cooper CL, McNeil CM, McFarland A, Nguyen A, Ormandy CJ, Qiu MR, Rabinovich B, Martelotto LG, Vu D, Hannigan GE, Musgrove EA, Christ D, Sutherland RL, Watkins DN, Swarbrick A.

Cancer Res. 2011 Jun 1;71(11):4002-14. doi: 10.1158/0008-5472.CAN-10-3738.

9.

Detection of integrin-linked kinase in the serum of patients with malignant pleural mesothelioma.

Watzka SB, Posch F, Pass HI, Huflejt M, Bernhard D, Hannigan GE, Müller MR.

J Thorac Cardiovasc Surg. 2011 Aug;142(2):384-9. doi: 10.1016/j.jtcvs.2011.04.034. Epub 2011 May 26.

10.

Integrin-linked kinase: not so 'pseudo' after all.

Hannigan GE, McDonald PC, Walsh MP, Dedhar S.

Oncogene. 2011 Oct 27;30(43):4375-85. doi: 10.1038/onc.2011.177. Epub 2011 May 23. Review.

PMID:
21602880
11.

Integrin-linked kinase is a functional Mn2+-dependent protein kinase that regulates glycogen synthase kinase-3β (GSK-3beta) phosphorylation.

Maydan M, McDonald PC, Sanghera J, Yan J, Rallis C, Pinchin S, Hannigan GE, Foster LJ, Ish-Horowicz D, Walsh MP, Dedhar S.

PLoS One. 2010 Aug 23;5(8):e12356. doi: 10.1371/journal.pone.0012356.

12.

The oncogenic and growth-suppressive functions of the integrin-linked kinase are distinguished by JNK1 expression in human cancer cells.

Durbin AD, Pasic I, Wong DK, Hannigan GE, Malkin D.

Cell Cycle. 2010 May 15;9(10):1951-9. Epub 2010 May 15.

PMID:
20495362
13.

Oncogenic ILK, tumor suppression and all that JNK.

Durbin AD, Hannigan GE, Malkin D.

Cell Cycle. 2009 Dec 15;8(24):4060-6. Epub 2009 Dec 15. Review.

PMID:
19923885
14.

JNK1 determines the oncogenic or tumor-suppressive activity of the integrin-linked kinase in human rhabdomyosarcoma.

Durbin AD, Somers GR, Forrester M, Pienkowska M, Hannigan GE, Malkin D.

J Clin Invest. 2009 Jun;119(6):1558-70. doi: 10.1172/JCI37958. Epub 2009 May 26.

15.

Integrin-linked kinase can facilitate syncytialization and hormonal differentiation of the human trophoblast-derived BeWo cell line.

Butler TM, Elustondo PA, Hannigan GE, MacPhee DJ.

Reprod Biol Endocrinol. 2009 May 22;7:51. doi: 10.1186/1477-7827-7-51.

16.

Parvin-beta inhibits breast cancer tumorigenicity and promotes CDK9-mediated peroxisome proliferator-activated receptor gamma 1 phosphorylation.

Johnstone CN, Mongroo PS, Rich AS, Schupp M, Bowser MJ, Delemos AS, Tobias JW, Liu Y, Hannigan GE, Rustgi AK.

Mol Cell Biol. 2008 Jan;28(2):687-704. Epub 2007 Nov 12.

17.

Integrin-linked kinase at the heart of cardiac contractility, repair, and disease.

Hannigan GE, Coles JG, Dedhar S.

Circ Res. 2007 May 25;100(10):1408-14. Review.

PMID:
17525380
18.

An essential role for the integrin-linked kinase-glycogen synthase kinase-3 beta pathway during dendrite initiation and growth.

Naska S, Park KJ, Hannigan GE, Dedhar S, Miller FD, Kaplan DR.

J Neurosci. 2006 Dec 20;26(51):13344-56.

19.

Integrin-linked kinase (ILK) is highly expressed in first trimester human chorionic villi and regulates migration of a human cytotrophoblast-derived cell line.

Elustondo PA, Hannigan GE, Caniggia I, MacPhee DJ.

Biol Reprod. 2006 May;74(5):959-68. Epub 2006 Jan 25.

PMID:
16436524
20.

Integrin-linked kinase mediates bone morphogenetic protein 7-dependent renal epithelial cell morphogenesis.

Leung-Hagesteijn C, Hu MC, Mahendra AS, Hartwig S, Klamut HJ, Rosenblum ND, Hannigan GE.

Mol Cell Biol. 2005 May;25(9):3648-57.

21.

Beta-parvin inhibits integrin-linked kinase signaling and is downregulated in breast cancer.

Mongroo PS, Johnstone CN, Naruszewicz I, Leung-Hagesteijn C, Sung RK, Carnio L, Rustgi AK, Hannigan GE.

Oncogene. 2004 Nov 25;23(55):8959-70.

PMID:
15467740
22.

Integrin-linked kinase regulates the nuclear entry of the c-Jun coactivator alpha-NAC and its coactivation potency.

Quélo I, Gauthier C, Hannigan GE, Dedhar S, St-Arnaud R.

J Biol Chem. 2004 Oct 15;279(42):43893-9. Epub 2004 Aug 6.

23.

Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas.

Hoek K, Rimm DL, Williams KR, Zhao H, Ariyan S, Lin A, Kluger HM, Berger AJ, Cheng E, Trombetta ES, Wu T, Niinobe M, Yoshikawa K, Hannigan GE, Halaban R.

Cancer Res. 2004 Aug 1;64(15):5270-82.

24.

ILKAP regulates ILK signaling and inhibits anchorage-independent growth.

Kumar AS, Naruszewicz I, Wang P, Leung-Hagesteijn C, Hannigan GE.

Oncogene. 2004 Apr 22;23(19):3454-61.

PMID:
14990992
25.

Integrin-linked kinase is a positive mediator of L6 myoblast differentiation.

Miller MG, Naruszewicz I, Kumar AS, Ramlal T, Hannigan GE.

Biochem Biophys Res Commun. 2003 Oct 24;310(3):796-803.

PMID:
14550274
26.

Modulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1.

Leung-Hagesteijn C, Mahendra A, Naruszewicz I, Hannigan GE.

EMBO J. 2001 May 1;20(9):2160-70.

27.

Mapping of the gene encoding the integrin-linked kinase, ILK, to human chromosome 11p15.5-p15.4.

Hannigan GE, Bayani J, Weksberg R, Beatty B, Pandita A, Dedhar S, Squire J.

Genomics. 1997 May 15;42(1):177-9.

PMID:
9177792
28.

Rescue of a Drosophila NF1 mutant phenotype by protein kinase A.

The I, Hannigan GE, Cowley GS, Reginald S, Zhong Y, Gusella JF, Hariharan IK, Bernards A.

Science. 1997 May 2;276(5313):791-4.

29.

Protein kinase mediators of integrin signal transduction.

Hannigan GE, Dedhar S.

J Mol Med (Berl). 1997 Jan;75(1):35-44. Review.

PMID:
9020382
30.

Integrin cytoplasmic interactions and bidirectional transmembrane signalling.

Dedhar S, Hannigan GE.

Curr Opin Cell Biol. 1996 Oct;8(5):657-69. Review.

PMID:
8939656
31.

Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase.

Hannigan GE, Leung-Hagesteijn C, Fitz-Gibbon L, Coppolino MG, Radeva G, Filmus J, Bell JC, Dedhar S.

Nature. 1996 Jan 4;379(6560):91-6.

PMID:
8538749
32.

Mouse neurofibromatosis type 1 cDNA sequence reveals high degree of conservation of both coding and non-coding mRNA segments.

Bernards A, Snijders AJ, Hannigan GE, Murthy AE, Gusella JF.

Hum Mol Genet. 1993 Jun;2(6):645-50.

PMID:
8353485
33.

Neurofibromatosis type 1 gene mutations in neuroblastoma.

The I, Murthy AE, Hannigan GE, Jacoby LB, Menon AG, Gusella JF, Bernards A.

Nat Genet. 1993 Jan;3(1):62-6.

PMID:
8490657
34.

Complete human NF1 cDNA sequence: two alternatively spliced mRNAs and absence of expression in a neuroblastoma line.

Bernards A, Haase VH, Murthy AE, Menon A, Hannigan GE, Gusella JF.

DNA Cell Biol. 1992 Dec;11(10):727-34.

PMID:
1457041
35.
38.

Signal transduction by interferon-alpha through arachidonic acid metabolism.

Hannigan GE, Williams BR.

Science. 1991 Jan 11;251(4990):204-7.

PMID:
1898993
39.

Interferon and growth factor modulation of nuclear factors binding to 5' upstream elements of the 2-5A synthetase gene.

Williams BR, Rutherford MN, Hannigan GE.

J Cell Biochem. 1988 Dec;38(4):261-7.

PMID:
3241014
40.

The interaction of interferon-alpha and -gamma: regulation of (2-5)A synthetase activity.

Fish EN, Hannigan GE, Banerjee K, Williams BR.

Virology. 1988 Jul;165(1):87-94.

PMID:
2455384
41.
42.

Roles of globotriosyl- and galabiosylceramide in verotoxin binding and high affinity interferon receptor.

Cohen A, Hannigan GE, Williams BR, Lingwood CA.

J Biol Chem. 1987 Dec 15;262(35):17088-91.

43.

Differential human interferon alpha receptor expression on proliferating and non-proliferating cells.

Hannigan GE, Lau AS, Williams BR.

Eur J Biochem. 1986 May 15;157(1):187-93.

44.

Regulation of interferon receptor expression in human blood lymphocytes in vitro and during interferon therapy.

Lau AS, Hannigan GE, Freedman MH, Williams BR.

J Clin Invest. 1986 May;77(5):1632-8.

45.

Cell growth-dependent changes in interferon-alpha receptor expression and induction of specific genes.

Williams BR, Hannigan GE, Saunders ME.

Prog Clin Biol Res. 1985;202:227-36. No abstract available.

PMID:
2938190
46.
47.

Modulation of human interferon-alpha receptor expression by human interferon-gamma.

Hannigan GE, Fish EN, Williams BR.

J Biol Chem. 1984 Jul 10;259(13):8084-6.

48.

Differential binding of human interferon-alpha subtypes to receptors on lymphoblastoid cells.

Hannigan GE, Gewert DR, Fish EN, Read SE, Williams BR.

Biochem Biophys Res Commun. 1983 Jan 27;110(2):537-44.

PMID:
6301456

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