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Items: 1 to 50 of 229

1.

Reliable gene mutation prediction in clear cell renal cell carcinoma through multi-classifier multi-objective radiogenomics model.

Chen X, Zhou Z, Hannan R, Thomas K, Pedrosa I, Kapur P, Brugarolas J, Mou X, Wang J.

Phys Med Biol. 2018 Oct 24;63(21):215008. doi: 10.1088/1361-6560/aae5cd.

PMID:
30277889
2.

Incidence and Outcomes of Delayed Targeted Therapy After Cytoreductive Nephrectomy for Metastatic Renal-Cell Carcinoma: A Nationwide Cancer Registry Study.

Woldu SL, Matulay JT, Clinton TN, Singla N, Freifeld Y, Sanli O, Krabbe LM, Hutchinson RC, Lotan Y, Hammers H, Hannan R, Brugarolas J, Bagrodia A, Margulis V.

Clin Genitourin Cancer. 2018 Aug 25. pii: S1558-7673(18)30444-0. doi: 10.1016/j.clgc.2018.08.001. [Epub ahead of print]

PMID:
30217763
3.

High-Content Imaging Approaches to Quantitate Stress-Induced Changes in Nucleolar Morphology.

He JS, Soo P, Evers M, Parsons KM, Hein N, Hannan KM, Hannan RD, George AJ.

Assay Drug Dev Technol. 2018 Aug/Sep;16(6):320-332. doi: 10.1089/adt.2018.861.

PMID:
30148664
4.

Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy.

Lawrence MG, Obinata D, Sandhu S, Selth LA, Wong SQ, Porter LH, Lister N, Pook D, Pezaro CJ, Goode DL, Rebello RJ, Clark AK, Papargiris M, Van Gramberg J, Hanson AR, Banks P, Wang H, Niranjan B, Keerthikumar S, Hedwards S, Huglo A, Yang R, Henzler C, Li Y, Lopez-Campos F, Castro E, Toivanen R, Azad A, Bolton D, Goad J, Grummet J, Harewood L, Kourambas J, Lawrentschuk N, Moon D, Murphy DG, Sengupta S, Snow R, Thorne H, Mitchell C, Pedersen J, Clouston D, Norden S, Ryan A, Dehm SM, Tilley WD, Pearson RB, Hannan RD, Frydenberg M, Furic L, Taylor RA, Risbridger GP.

Eur Urol. 2018 Nov;74(5):562-572. doi: 10.1016/j.eururo.2018.06.020. Epub 2018 Jul 23.

PMID:
30049486
5.

Safety and efficacy of concurrent immune checkpoint inhibitors and hypofractionated body radiotherapy.

Mohamad O, Diaz de Leon A, Schroeder S, Leiker A, Christie A, Zhang-Velten E, Trivedi L, Khan S, Desai NB, Laine A, Albuquerque K, Iyengar P, Arriaga Y, Courtney K, Gerber DE, Hammers H, Choy H, Timmerman R, Brugarolas J, Hannan R.

Oncoimmunology. 2018 Mar 15;7(7):e1440168. doi: 10.1080/2162402X.2018.1440168. eCollection 2018.

PMID:
29900043
6.

An Empirical Approach Leveraging Tumorgrafts to Dissect the Tumor Microenvironment in Renal Cell Carcinoma Identifies Missing Link to Prognostic Inflammatory Factors.

Wang T, Lu R, Kapur P, Jaiswal BS, Hannan R, Zhang Z, Pedrosa I, Luke JJ, Zhang H, Goldstein LD, Yousuf Q, Gu YF, McKenzie T, Joyce A, Kim MS, Wang X, Luo D, Onabolu O, Stevens C, Xie Z, Chen M, Filatenkov A, Torrealba J, Luo X, Guo W, He J, Stawiski E, Modrusan Z, Durinck S, Seshagiri S, Brugarolas J.

Cancer Discov. 2018 Sep;8(9):1142-1155. doi: 10.1158/2159-8290.CD-17-1246. Epub 2018 Jun 8.

PMID:
29884728
7.

Controlling Fibrin Network Morphology, Polymerization, and Degradation Dynamics in Fibrin Gels for Promoting Tissue Repair.

Sproul EP, Hannan RT, Brown AC.

Methods Mol Biol. 2018;1758:85-99. doi: 10.1007/978-1-4939-7741-3_7.

PMID:
29679324
8.

Ribosomal DNA copy loss and repeat instability in ATRX-mutated cancers.

Udugama M, Sanij E, Voon HPJ, Son J, Hii L, Henson JD, Chan FL, Chang FTM, Liu Y, Pearson RB, Kalitsis P, Mann JR, Collas P, Hannan RD, Wong LH.

Proc Natl Acad Sci U S A. 2018 May 1;115(18):4737-4742. doi: 10.1073/pnas.1720391115. Epub 2018 Apr 18.

9.

PD-L1 on host cells is essential for PD-L1 blockade-mediated tumor regression.

Tang H, Liang Y, Anders RA, Taube JM, Qiu X, Mulgaonkar A, Liu X, Harrington SM, Guo J, Xin Y, Xiong Y, Nham K, Silvers W, Hao G, Sun X, Chen M, Hannan R, Qiao J, Dong H, Peng H, Fu YX.

J Clin Invest. 2018 Feb 1;128(2):580-588. doi: 10.1172/JCI96061. Epub 2018 Jan 16.

10.

Palbociclib synergizes with BRAF and MEK inhibitors in treatment naïve melanoma but not after the development of BRAF inhibitor resistance.

Martin CA, Cullinane C, Kirby L, Abuhammad S, Lelliott EJ, Waldeck K, Young RJ, Brajanovski N, Cameron DP, Walker R, Sanij E, Poortinga G, Hannan RD, Pearson RB, Hicks RJ, McArthur GA, Sheppard KE.

Int J Cancer. 2018 May 15;142(10):2139-2152. doi: 10.1002/ijc.31220. Epub 2018 Jan 3.

PMID:
29243224
11.

How should new orthopaedic implants be introduced: an example and recommendations for best practice.

Hannan R, Arora V, Beaver R, Harvie P.

ANZ J Surg. 2018 Apr;88(4):284-289. doi: 10.1111/ans.14234. Epub 2017 Nov 9. Review.

PMID:
29124832
12.

Self-reverting mutations partially correct the blood phenotype in a Diamond Blackfan anemia patient.

Venugopal P, Moore S, Lawrence DM, George AJ, Hannan RD, Bray SC, To LB, D'Andrea RJ, Feng J, Tirimacco A, Yeoman AL, Young CC, Fine M, Schreiber AW, Hahn CN, Barnett C, Saxon B, Scott HS.

Haematologica. 2017 Dec;102(12):e506-e509. doi: 10.3324/haematol.2017.166678. Epub 2017 Sep 29. No abstract available.

13.

Comparison of stored red blood cell washing techniques for priming extracorporeal circuits.

Sasaki J, Tirotta C, Lim H, Kubes K, Salvaggio J, Hannan R, Burke R, Ojito J.

Perfusion. 2018 Mar;33(2):130-135. doi: 10.1177/0267659117730134. Epub 2017 Sep 19.

PMID:
28925857
14.

Dosimetric comparison of rectal-sparing capabilities of rectal balloon vs injectable spacer gel in stereotactic body radiation therapy for prostate cancer: lessons learned from prospective trials.

Jones RT, Hassan Rezaeian N, Desai NB, Lotan Y, Jia X, Hannan R, Kim DWN, Hornberger B, Dubas J, Laine AM, Zelefsky MJ, Timmerman RD, Folkert MR.

Med Dosim. 2017 Winter;42(4):341-347. doi: 10.1016/j.meddos.2017.07.002. Epub 2017 Jul 31.

PMID:
28774760
15.

Transcriptional profiles for distinct aggregation states of mutant Huntingtin exon 1 protein unmask new Huntington's disease pathways.

Moily NS, Ormsby AR, Stojilovic A, Ramdzan YM, Diesch J, Hannan RD, Zajac MS, Hannan AJ, Oshlack A, Hatters DM.

Mol Cell Neurosci. 2017 Sep;83:103-112. doi: 10.1016/j.mcn.2017.07.004. Epub 2017 Jul 23.

PMID:
28743452
16.

A new method to reconstruct intra-fractional prostate motion in volumetric modulated arc therapy.

Chi Y, Rezaeian NH, Shen C, Zhou Y, Lu W, Yang M, Hannan R, Jia X.

Phys Med Biol. 2017 Jul 7;62(13):5509-5530. doi: 10.1088/1361-6560/aa6e37.

17.

Safety and Efficacy of Stereotactic Ablative Radiation Therapy for Renal Cell Carcinoma Extracranial Metastases.

Wang CJ, Christie A, Lin MH, Jung M, Weix D, Huelsmann L, Kuhn K, Meyer J, Desai N, Kim DWN, Pedrosa I, Margulis V, Cadeddu J, Sagalowsky A, Gahan J, Laine A, Xie XJ, Choy H, Brugarolas J, Timmerman R, Hannan R.

Int J Radiat Oncol Biol Phys. 2017 May 1;98(1):91-100. doi: 10.1016/j.ijrobp.2017.01.032.

18.

Natural history of 'second' biochemical failure after salvage radiation therapy for prostate cancer: a multi-institution study.

Tumati V, Jackson WC, Abugharib AE, Raj G, Roehrborn C, Lotan Y, Courtney K, Bagrodia A, Gahan JC, Zumsteg ZS, Folkert MR, Laine AM, Hannan R, Spratt DE, Desai NB.

BJU Int. 2018 Mar;121(3):365-372. doi: 10.1111/bju.13926. Epub 2017 Jul 5.

PMID:
28581200
19.

Non-invasive cardiac output monitor validation study in pediatric cardiac surgery patients.

Tirotta CF, Lagueruela RG, Madril D, Velis E, Ojito J, Monroe D, Aguero D, Irizarry M, McBride J, Hannan RL, Burke RP.

J Clin Anesth. 2017 May;38:129-132. doi: 10.1016/j.jclinane.2017.02.001. Epub 2017 Feb 12.

PMID:
28372651
20.

Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population.

Hein N, Cameron DP, Hannan KM, Nguyen NN, Fong CY, Sornkom J, Wall M, Pavy M, Cullinane C, Diesch J, Devlin JR, George AJ, Sanij E, Quin J, Poortinga G, Verbrugge I, Baker A, Drygin D, Harrison SJ, Rozario JD, Powell JA, Pitson SM, Zuber J, Johnstone RW, Dawson MA, Guthridge MA, Wei A, McArthur GA, Pearson RB, Hannan RD.

Blood. 2017 May 25;129(21):2882-2895. doi: 10.1182/blood-2016-05-718171. Epub 2017 Mar 10.

21.

Selective inhibition of RNA polymerase I transcription as a potential approach to treat African trypanosomiasis.

Kerry LE, Pegg EE, Cameron DP, Budzak J, Poortinga G, Hannan KM, Hannan RD, Rudenko G.

PLoS Negl Trop Dis. 2017 Mar 6;11(3):e0005432. doi: 10.1371/journal.pntd.0005432. eCollection 2017 Mar.

22.

Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene.

Lefebure M, Tothill RW, Kruse E, Hawkins ED, Shortt J, Matthews GM, Gregory GP, Martin BP, Kelly MJ, Todorovski I, Doyle MA, Lupat R, Li J, Schroeder J, Wall M, Craig S, Poortinga G, Cameron D, Bywater M, Kats L, Gearhart MD, Bardwell VJ, Dickins RA, Hannan RD, Papenfuss AT, Johnstone RW.

Nat Commun. 2017 Mar 6;8:14581. doi: 10.1038/ncomms14581.

23.

Therapeutic Approaches Targeting MYC-Driven Prostate Cancer.

Rebello RJ, Pearson RB, Hannan RD, Furic L.

Genes (Basel). 2017 Feb 16;8(2). pii: E71. doi: 10.3390/genes8020071. Review.

24.

Anatomical patterns of recurrence following biochemical relapse after post-prostatectomy salvage radiation therapy: a multi-institutional study.

Jackson WC, Desai NB, Abugharib AE, Tumati V, Dess RT, Lee JY, Zhao SG, Soliman M, Folkert M, Laine A, Hannan R, Zumsteg ZS, Sandler H, Hamstra DA, Montgomery JS, Miller DC, Kozminski MA, Hollenbeck BK, Hearn JW, Palapattu G, Tomlins SA, Mehra R, Morgan TM, Feng FY, Spratt DE.

BJU Int. 2017 Sep;120(3):351-357. doi: 10.1111/bju.13792. Epub 2017 Feb 26.

25.

The Potential of Targeting Ribosome Biogenesis in High-Grade Serous Ovarian Cancer.

Yan S, Frank D, Son J, Hannan KM, Hannan RD, Chan KT, Pearson RB, Sanij E.

Int J Mol Sci. 2017 Jan 20;18(1). pii: E210. doi: 10.3390/ijms18010210. Review.

26.

Cell cycle and growth stimuli regulate different steps of RNA polymerase I transcription.

Hung SS, Lesmana A, Peck A, Lee R, Tchoubrieva E, Hannan KM, Lin J, Sheppard KE, Jastrzebski K, Quinn LM, Rothblum LI, Pearson RB, Hannan RD, Sanij E.

Gene. 2017 May 15;612:36-48. doi: 10.1016/j.gene.2016.12.015. Epub 2016 Dec 15.

PMID:
27989772
27.

Evaluation of Residual Coarctation in Infants with a Single Right Ventricle after Stage I Palliation.

Fundora MP, Sasaki J, Muniz JC, Rossi A, Rhodes JF Jr, Hannan RL, Burke RP, Lopez L.

Pediatr Cardiol. 2017 Jan;38(1):115-122. doi: 10.1007/s00246-016-1490-8. Epub 2016 Nov 11.

PMID:
27833994
28.

A cadaver study validating CT assessment of acetabular component orientation: the Perth CT hip protocol.

Arora V, Hannan R, Beaver R, Fletcher T, Harvie P.

Skeletal Radiol. 2017 Feb;46(2):177-183. doi: 10.1007/s00256-016-2527-z. Epub 2016 Nov 8.

PMID:
27826701
29.

Rationale and evidence to combine radiation therapy and immunotherapy for cancer treatment.

Ishihara D, Pop L, Takeshima T, Iyengar P, Hannan R.

Cancer Immunol Immunother. 2017 Mar;66(3):281-298. doi: 10.1007/s00262-016-1914-6. Epub 2016 Oct 14. Review.

PMID:
27743027
30.

Key role for neutrophils in radiation-induced antitumor immune responses: Potentiation with G-CSF.

Takeshima T, Pop LM, Laine A, Iyengar P, Vitetta ES, Hannan R.

Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11300-11305. Epub 2016 Sep 20.

31.

Clustered somatic mutations are frequent in transcription factor binding motifs within proximal promoter regions in melanoma and other cutaneous malignancies.

Colebatch AJ, Di Stefano L, Wong SQ, Hannan RD, Waring PM, Dobrovic A, McArthur GA, Papenfuss AT.

Oncotarget. 2016 Oct 11;7(41):66569-66585. doi: 10.18632/oncotarget.11892.

32.

Combining High-Content Imaging and Phenotypic Classification Analysis of Senescence-Associated Beta-Galactosidase Staining to Identify Regulators of Oncogene-Induced Senescence.

Chan KT, Paavolainen L, Hannan KM, George AJ, Hannan RD, Simpson KJ, Horvath P, Pearson RB.

Assay Drug Dev Technol. 2016 Sep;14(7):416-28. doi: 10.1089/adt.2016.739.

PMID:
27552145
33.

The Dual Inhibition of RNA Pol I Transcription and PIM Kinase as a New Therapeutic Approach to Treat Advanced Prostate Cancer.

Rebello RJ, Kusnadi E, Cameron DP, Pearson HB, Lesmana A, Devlin JR, Drygin D, Clark AK, Porter L, Pedersen J, Sandhu S, Risbridger GP, Pearson RB, Hannan RD, Furic L.

Clin Cancer Res. 2016 Nov 15;22(22):5539-5552. doi: 10.1158/1078-0432.CCR-16-0124. Epub 2016 Aug 2.

34.

Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling.

Quin J, Chan KT, Devlin JR, Cameron DP, Diesch J, Cullinane C, Ahern J, Khot A, Hein N, George AJ, Hannan KM, Poortinga G, Sheppard KE, Khanna KK, Johnstone RW, Drygin D, McArthur GA, Pearson RB, Sanij E, Hannan RD.

Oncotarget. 2016 Aug 2;7(31):49800-49818. doi: 10.18632/oncotarget.10452.

35.

Amino acid-dependent signaling via S6K1 and MYC is essential for regulation of rDNA transcription.

Kang J, Kusnadi EP, Ogden AJ, Hicks RJ, Bammert L, Kutay U, Hung S, Sanij E, Hannan RD, Hannan KM, Pearson RB.

Oncotarget. 2016 Aug 2;7(31):48887-48904. doi: 10.18632/oncotarget.10346.

36.

Defining the essential function of FBP/KSRP proteins: Drosophila Psi interacts with the mediator complex to modulate MYC transcription and tissue growth.

Guo L, Zaysteva O, Nie Z, Mitchell NC, Amanda Lee JE, Ware T, Parsons L, Luwor R, Poortinga G, Hannan RD, Levens DL, Quinn LM.

Nucleic Acids Res. 2016 Sep 19;44(16):7646-58. doi: 10.1093/nar/gkw461. Epub 2016 May 20.

37.

Preoperative Intubation and Lack of Enteral Nutrition are Associated with Prolonged Stay After Arterial Switch Operation.

Iliopoulos I, Burke R, Hannan R, Bolivar J, Cooper DS, Zafar F, Rossi A.

Pediatr Cardiol. 2016 Aug;37(6):1078-84. doi: 10.1007/s00246-016-1394-7. Epub 2016 Apr 15.

PMID:
27084382
38.

Stereotactic body radiation therapy for low and intermediate risk prostate cancer-Results from a multi-institutional clinical trial.

Hannan R, Tumati V, Xie XJ, Cho LC, Kavanagh BD, Brindle J, Raben D, Nanda A, Cooley S, Kim DWN, Pistenmaa D, Lotan Y, Timmerman R.

Eur J Cancer. 2016 May;59:142-151. doi: 10.1016/j.ejca.2016.02.014. Epub 2016 Mar 29.

PMID:
27035363
39.

Echocardiographic and Surgical Correlation of Coronary Artery Patterns in Transposition of the Great Arteries.

Fundora MP, Aregullin EO, Wernovsky G, Welch EM, Muniz JC, Sasaki N, Hannan RL, Burke RP, Lopez L.

Congenit Heart Dis. 2016 Dec;11(6):570-577. doi: 10.1111/chd.12338. Epub 2016 Mar 2.

PMID:
26931510
40.

Risk Factors for Longer Hospital Stay Following the Fontan Operation.

Sasaki J, Dykes JC, Sosa LJ, Salvaggio JL, Tablante MD, Ojito J, Khan DM, Hannan RL, Rossi AF, Burke RP, Wernovsky G.

Pediatr Crit Care Med. 2016 May;17(5):411-9. doi: 10.1097/PCC.0000000000000701.

PMID:
26927939
41.

Fibrin Network Changes in Neonates after Cardiopulmonary Bypass.

Brown AC, Hannan RT, Timmins LH, Fernandez JD, Barker TH, Guzzetta NA.

Anesthesiology. 2016 May;124(5):1021-31. doi: 10.1097/ALN.0000000000001058. Erratum in: Anesthesiology. 2016 Sep;125(3):610.

42.

Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma.

Devlin JR, Hannan KM, Hein N, Cullinane C, Kusnadi E, Ng PY, George AJ, Shortt J, Bywater MJ, Poortinga G, Sanij E, Kang J, Drygin D, O'Brien S, Johnstone RW, McArthur GA, Hannan RD, Pearson RB.

Cancer Discov. 2016 Jan;6(1):59-70. doi: 10.1158/2159-8290.CD-14-0673. Epub 2015 Oct 21.

43.

Genome wide mapping of UBF binding-sites in mouse and human cell lines.

Diesch J, Hannan RD, Sanij E.

Genom Data. 2015 Jan 5;3:103-5. doi: 10.1016/j.gdata.2014.12.005. eCollection 2015 Mar.

44.

Pretreatment biopsy analysis of DAB2IP identifies subpopulation of high-risk prostate cancer patients with worse survival following radiation therapy.

Jacobs C, Tumati V, Kapur P, Yan J, Xie XJ, Hannan R, Hsieh JT, Kim DW, Saha D.

Cancer Med. 2015 Dec;4(12):1844-52. doi: 10.1002/cam4.554. Epub 2015 Oct 16.

45.

Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia.

Sjögren SE, Siva K, Soneji S, George AJ, Winkler M, Jaako P, Wlodarski M, Karlsson S, Hannan RD, Flygare J.

Br J Haematol. 2015 Nov;171(4):517-29. doi: 10.1111/bjh.13632. Epub 2015 Aug 25.

46.

S6 Kinase is essential for MYC-dependent rDNA transcription in Drosophila.

Mitchell NC, Tchoubrieva EB, Chahal A, Woods S, Lee A, Lin JI, Parsons L, Jastrzebski K, Poortinga G, Hannan KM, Pearson RB, Hannan RD, Quinn LM.

Cell Signal. 2015 Oct;27(10):2045-53. doi: 10.1016/j.cellsig.2015.07.018. Epub 2015 Jul 26.

PMID:
26215099
47.

Defective Hfp-dependent transcriptional repression of dMYC is fundamental to tissue overgrowth in Drosophila XPB models.

Lee JE, Mitchell NC, Zaytseva O, Chahal A, Mendis P, Cartier-Michaud A, Parsons LM, Poortinga G, Levens DL, Hannan RD, Quinn LM.

Nat Commun. 2015 Jun 15;6:7404. doi: 10.1038/ncomms8404.

PMID:
26074141
48.

A Phase I Dose-Escalation Trial of Single-Fraction Stereotactic Radiation Therapy for Liver Metastases.

Meyer JJ, Foster RD, Lev-Cohain N, Yokoo T, Dong Y, Schwarz RE, Rule W, Tian J, Xie Y, Hannan R, Nedzi L, Solberg T, Timmerman R.

Ann Surg Oncol. 2016 Jan;23(1):218-24. doi: 10.1245/s10434-015-4579-z. Epub 2015 May 12.

49.

Stereotactic radiation therapy of renal cancer inferior vena cava tumor thrombus.

Hannan R, Margulis V, Chun SG, Cannon N, Kim DW, Abdulrahman RE, Sagalowsky A, Pedrosa I, Choy H, Brugarolas J, Timmerman RD.

Cancer Biol Ther. 2015;16(5):657-61. doi: 10.1080/15384047.2015.1026506.

50.

Unexpected role of CDK4 in a G2/M checkpoint.

Sheppard KE, Pearson RB, Hannan RD.

Cell Cycle. 2015;14(9):1351-2. doi: 10.1080/15384101.2015.1022060. No abstract available.

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