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Items: 1 to 50 of 124

1.

Circulating adrenomedullin mRNA is decreased in women destined to develop term preeclampsia.

Whigham CA, MacDonald TM, Walker SP, Pritchard N, Hannan NJ, Hastie R, Alwis N, Cannon P, Nguyen TV, Tong S, Kaitu'u-Lino T.

Pregnancy Hypertens. 2019 Apr;16:16-25. doi: 10.1016/j.preghy.2019.02.003. Epub 2019 Feb 10.

PMID:
31056153
2.

Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth.

Thilakasiri P, Huynh J, Poh AR, Tan CW, Nero TL, Tran K, Parslow AC, Afshar-Sterle S, Baloyan D, Hannan NJ, Buchert M, Scott AM, Griffin MD, Hollande F, Parker MW, Putoczki TL, Ernst M, Chand AL.

EMBO Mol Med. 2019 Apr;11(4). pii: e9539. doi: 10.15252/emmm.201809539.

3.

Proton Pump Inhibitors and Preeclampsia Risk Among 157 720 Women.

Hastie R, Bergman L, Cluver CA, Wikman A, Hannan NJ, Walker SP, Wikström AK, Tong S, Hesselman S.

Hypertension. 2019 May;73(5):1097-1103. doi: 10.1161/HYPERTENSIONAHA.118.12547.

PMID:
30827143
4.

Sulfasalazine reduces placental secretion of antiangiogenic factors, up-regulates the secretion of placental growth factor and rescues endothelial dysfunction.

Brownfoot FC, Hannan NJ, Cannon P, Nguyen V, Hastie R, Parry LJ, Senadheera S, Tuohey L, Tong S, Kaitu'u-Lino TJ.

EBioMedicine. 2019 Mar;41:636-648. doi: 10.1016/j.ebiom.2019.02.013. Epub 2019 Feb 26.

5.

Sugar off the shelves.

Hannan N, Dagher A.

Br Dent J. 2019 Feb;226(4):241. doi: 10.1038/s41415-019-0039-7. No abstract available.

PMID:
30796379
6.

Mouthwash: more harm than good?

Dagher A, Hannan N.

Br Dent J. 2019 Feb;226(4):240. doi: 10.1038/s41415-019-0036-x. No abstract available.

PMID:
30796376
7.

IFPA meeting 2018 workshop report II: Abnormally invasive placenta; inflammation and infection; preeclampsia; gestational trophoblastic disease and drug delivery.

Albrecht C, Chamley L, Charnock-Jones DS, Collins S, Fujiwara H, Golos T, Grayo S, Hannan N, Harris L, Ichizuka K, Illsley NP, Iwashita M, Kallol S, Al-Khan A, Lash G, Nagamatsu T, Nakashima A, Niimi K, Nomoto M, Redman C, Saito S, Tanimura K, Tomi M, Usui H, Vatish M, Wolfe B, Yamamoto E, O'Tierney-Ginn P.

Placenta. 2019 Feb 12. pii: S0143-4004(18)31200-1. doi: 10.1016/j.placenta.2019.02.006. [Epub ahead of print] Review.

PMID:
30773233
8.

The untapped potential of placenta-enriched molecules for diagnostic and therapeutic development.

Whigham CA, MacDonald TM, Walker SP, Hannan NJ, Tong S, Kaitu'u-Lino TJ.

Placenta. 2019 Feb 4. pii: S0143-4004(18)31203-7. doi: 10.1016/j.placenta.2019.02.002. [Epub ahead of print] Review.

PMID:
30745114
9.

Circulating GATA2 mRNA is decreased among women destined to develop preeclampsia and may be of endothelial origin.

Whigham CA, MacDonald TM, Walker SP, Pritchard N, Hannan NJ, Cannon P, Nguyen TV, Hastie R, Tong S, Kaitu'u-Lino TJ.

Sci Rep. 2019 Jan 18;9(1):235. doi: 10.1038/s41598-018-36645-0.

10.

EGFR (Epidermal Growth Factor Receptor) Signaling and the Mitochondria Regulate sFlt-1 (Soluble FMS-Like Tyrosine Kinase-1) Secretion.

Hastie R, Brownfoot FC, Pritchard N, Hannan NJ, Cannon P, Nguyen V, Palmer K, Beard S, Tong S, Kaitu'u-Lino TJ.

Hypertension. 2019 Mar;73(3):659-670. doi: 10.1161/HYPERTENSIONAHA.118.12300.

PMID:
30636550
11.

Disulfiram inhibits placental soluble FMS-like tyrosine kinase-1 and soluble endoglin secretion independent of the proteasome.

Hastie R, Ye L, Hannan NJ, Brownfoot FC, Cannon P, Nguyen V, Tong S, Kaitu'u-Lino TJ.

Pregnancy Hypertens. 2018 Oct;14:125-130. doi: 10.1016/j.preghy.2018.09.005. Epub 2018 Sep 21.

PMID:
30527099
12.

EGFL7 gene expression is regulated by hypoxia in trophoblast and altered in the plasma of patients with early preeclampsia.

Whitehead CL, Kaitu'u-Lino TJ, Binder NK, Beard S, De Alwis N, Brownfoot F, Tong S, Hannan NJ.

Pregnancy Hypertens. 2018 Oct;14:115-120. doi: 10.1016/j.preghy.2018.09.001. Epub 2018 Sep 5.

PMID:
30527097
13.

Reply.

Cluver C, Hannan N, Tong S.

Am J Obstet Gynecol. 2019 Feb;220(2):207. doi: 10.1016/j.ajog.2018.10.009. Epub 2018 Oct 10. No abstract available.

PMID:
30315783
14.

Effect of sildenafil citrate on circulating levels of sFlt-1 in preeclampsia.

Brownfoot FC, Tong S, Hannan NJ, Cannon P, Nguyen V, Kaitu'u-Lino TJ.

Pregnancy Hypertens. 2018 Jul;13:1-6. doi: 10.1016/j.preghy.2018.04.011. Epub 2018 Apr 11.

PMID:
30177033
15.

Esomeprazole to treat women with preterm preeclampsia: a randomized placebo controlled trial.

Cluver CA, Hannan NJ, van Papendorp E, Hiscock R, Beard S, Mol BW, Theron GB, Hall DR, Decloedt EH, Stander M, Adams KT, Rensburg M, Schubert P, Walker SP, Tong S.

Am J Obstet Gynecol. 2018 Oct;219(4):388.e1-388.e17. doi: 10.1016/j.ajog.2018.07.019. Epub 2018 Jul 26.

PMID:
30055127
16.

hiPSC hepatocyte model demonstrates the role of unfolded protein response and inflammatory networks in α1-antitrypsin deficiency.

Segeritz CP, Rashid ST, de Brito MC, Serra MP, Ordonez A, Morell CM, Kaserman JE, Madrigal P, Hannan NRF, Gatto L, Tan L, Wilson AA, Lilley K, Marciniak SJ, Gooptu B, Lomas DA, Vallier L.

J Hepatol. 2018 Oct;69(4):851-860. doi: 10.1016/j.jhep.2018.05.028. Epub 2018 Jun 5.

17.

Intestinal organoids for modelling intestinal development and disease.

Fair KL, Colquhoun J, Hannan NRF.

Philos Trans R Soc Lond B Biol Sci. 2018 Jul 5;373(1750). pii: 20170217. doi: 10.1098/rstb.2017.0217. Review.

18.
19.

Combining metformin and esomeprazole is additive in reducing sFlt-1 secretion and decreasing endothelial dysfunction - implications for treating preeclampsia.

Kaitu'u-Lino TJ, Brownfoot FC, Beard S, Cannon P, Hastie R, Nguyen TV, Binder NK, Tong S, Hannan NJ.

PLoS One. 2018 Feb 21;13(2):e0188845. doi: 10.1371/journal.pone.0188845. eCollection 2018.

20.

Vinorelbine Potently Induces Placental Cell Death, Does Not Harm Fertility and is a Potential Treatment for Ectopic Pregnancy.

Hastie R, Lim E, Sluka P, Campbell L, Horne AW, Ellett L, Hannan NJ, Brownfoot F, Kaitu'u-Lino TJ, Tong S.

EBioMedicine. 2018 Mar;29:166-176. doi: 10.1016/j.ebiom.2018.01.041. Epub 2018 Feb 2.

21.

IFPA meeting 2017 workshop report: Clinical placentology, 3D structure-based modeling of placental function, placental bed, and treating placental dysfunction.

Acharya G, Aplin J, Brownbill P, Bulmer J, Burton G, Chamley L, Chernyavsky I, Clark A, Collins S, Cottrell E, Dilworth M, Elad D, Filoche M, Hannan N, Heazell AEP, Jensen O, Johnstone ED, Leach L, Lewis R, Morgan T, Myers J, Nye G, Oyen M, Salafia C, Schneider H, O'Tierney-Ginn P.

Placenta. 2018 Apr;64 Suppl 1:S4-S8. doi: 10.1016/j.placenta.2017.12.011. Epub 2017 Dec 15.

PMID:
29273272
22.

Animal models of preeclampsia: translational failings and why.

Marshall SA, Hannan NJ, Jelinic M, Nguyen TPH, Girling JE, Parry LJ.

Am J Physiol Regul Integr Comp Physiol. 2018 Apr 1;314(4):R499-R508. doi: 10.1152/ajpregu.00355.2017. Epub 2017 Dec 6.

23.

sFlt-1 and soluble endoglin concentrations in serum vs plasma in preterm preeclampsia: Are they interchangeable for biomarker studies?

Brownfoot F, Kaitu'u-Lino T, Beard S, Tong S, Hannan N.

Pregnancy Hypertens. 2017 Oct;10:18-21. doi: 10.1016/j.preghy.2017.07.138. Epub 2017 Jul 22.

PMID:
29153675
24.

Activating Transcription Factor 3 Is Reduced in Preeclamptic Placentas and Negatively Regulates sFlt-1 (Soluble fms-Like Tyrosine Kinase 1), Soluble Endoglin, and Proinflammatory Cytokines in Placenta.

Kaitu'u-Lino TJ, Brownfoot FC, Hastie R, Chand A, Cannon P, Deo M, Tuohey L, Whitehead C, Hannan NJ, Tong S.

Hypertension. 2017 Nov;70(5):1014-1024. doi: 10.1161/HYPERTENSIONAHA.117.09548. Epub 2017 Sep 25.

PMID:
28947613
25.

Immunostaining for DNA Modifications: Computational Analysis of Confocal Images.

Ramsawhook AH, Lewis LC, Eleftheriou M, Abakir A, Durczak P, Markus R, Rajani S, Hannan NRF, Coyle B, Ruzov A.

J Vis Exp. 2017 Sep 7;(127). doi: 10.3791/56318.

26.

Teaching Tip: Simulated Tumors as an Aid to Teaching Principles of Surgical Oncology.

Tan C, Basa R, Bennett P, Hannan N, Walsh WR, Bellenger C.

J Vet Med Educ. Summer 2018;45(2):250-254. doi: 10.3138/jvme.1116-183r. Epub 2017 Sep 8.

PMID:
28885872
27.

Measuring fetal brain and lung transcripts in amniotic fluid supernatant: a comparison of digital PCR and RT-qPCR methods.

Hui L, Beard S, Hannan NJ.

J Matern Fetal Neonatal Med. 2018 Dec;31(23):3191-3196. doi: 10.1080/14767058.2017.1367378. Epub 2017 Aug 24.

PMID:
28805106
28.

Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids.

Sampaziotis F, Justin AW, Tysoe OC, Sawiak S, Godfrey EM, Upponi SS, Gieseck RL 3rd, de Brito MC, Berntsen NL, Gómez-Vázquez MJ, Ortmann D, Yiangou L, Ross A, Bargehr J, Bertero A, Zonneveld MCF, Pedersen MT, Pawlowski M, Valestrand L, Madrigal P, Georgakopoulos N, Pirmadjid N, Skeldon GM, Casey J, Shu W, Materek PM, Snijders KE, Brown SE, Rimland CA, Simonic I, Davies SE, Jensen KB, Zilbauer M, Gelson WTH, Alexander GJ, Sinha S, Hannan NRF, Wynn TA, Karlsen TH, Melum E, Markaki AE, Saeb-Parsy K, Vallier L.

Nat Med. 2017 Aug;23(8):954-963. doi: 10.1038/nm.4360. Epub 2017 Jul 3.

29.

Resveratrol inhibits release of soluble fms-like tyrosine kinase (sFlt-1) and soluble endoglin and improves vascular dysfunction - implications as a preeclampsia treatment.

Hannan NJ, Brownfoot FC, Cannon P, Deo M, Beard S, Nguyen TV, Palmer KR, Tong S, Kaitu'u-Lino TJ.

Sci Rep. 2017 May 12;7(1):1819. doi: 10.1038/s41598-017-01993-w.

30.

The circulating microRNA-200 family in whole blood are potential biomarkers for high-grade serous epithelial ovarian cancer.

Pendlebury A, Hannan NJ, Binder N, Beard S, Mcgauran M, Grant P, Tong S, Whitehead CL.

Biomed Rep. 2017 Mar;6(3):319-322. doi: 10.3892/br.2017.847. Epub 2017 Jan 25.

31.

The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma.

Coulson R, Liew SH, Connelly AA, Yee NS, Deb S, Kumar B, Vargas AC, O'Toole SA, Parslow AC, Poh A, Putoczki T, Morrow RJ, Alorro M, Lazarus KA, Yeap EFW, Walton KL, Harrison CA, Hannan NJ, George AJ, Clyne CD, Ernst M, Allen AM, Chand AL.

Oncotarget. 2017 Mar 21;8(12):18640-18656. doi: 10.18632/oncotarget.15553.

32.

Relaxin treatment reduces angiotensin II-induced vasoconstriction in pregnancy and protects against endothelial dysfunction†.

Marshall SA, Leo CH, Girling JE, Tare M, Beard S, Hannan NJ, Parry LJ.

Biol Reprod. 2017 Apr 1;96(4):895-906. doi: 10.1093/biolre/iox023.

PMID:
28379296
33.

Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells.

Sampaziotis F, de Brito MC, Geti I, Bertero A, Hannan NR, Vallier L.

Nat Protoc. 2017 Apr;12(4):814-827. doi: 10.1038/nprot.2017.011. Epub 2017 Mar 23.

34.

Key players of the necroptosis pathway RIPK1 and SIRT2 are altered in placenta from preeclampsia and fetal growth restriction.

Hannan NJ, Beard S, Binder NK, Onda K, Kaitu'u-Lino TJ, Chen Q, Tuohey L, De Silva M, Tong S.

Placenta. 2017 Mar;51:1-9. doi: 10.1016/j.placenta.2017.01.002. Epub 2017 Jan 4.

PMID:
28292463
35.

Dynamics of 5-carboxylcytosine during hepatic differentiation: Potential general role for active demethylation by DNA repair in lineage specification.

Lewis LC, Lo PC, Foster JM, Dai N, Corrêa IR, Durczak PM, Duncan G, Ramsawhook A, Aithal GP, Denning C, Hannan NR, Ruzov A.

Epigenetics. 2017 Apr 3;12(4):277-286. doi: 10.1080/15592294.2017.1292189. Epub 2017 Mar 7.

36.

Enoxaparin for the prevention of preeclampsia and intrauterine growth restriction in women with a history: a randomized trial.

Groom KM, McCowan LM, Mackay LK, Lee AC, Said JM, Kane SC, Walker SP, van Mens TE, Hannan NJ, Tong S, Chamley LW, Stone PR, McLintock C; Enoxaparin for Prevention of Preeclampsia and Intrauterine Growth Restriction Trial Investigator Group.

Am J Obstet Gynecol. 2017 Mar;216(3):296.e1-296.e14. doi: 10.1016/j.ajog.2017.01.014. Epub 2017 Jan 30.

PMID:
28153659
37.

Proton Pump Inhibitors Decrease Soluble fms-Like Tyrosine Kinase-1 and Soluble Endoglin Secretion, Decrease Hypertension, and Rescue Endothelial Dysfunction.

Onda K, Tong S, Beard S, Binder N, Muto M, Senadheera SN, Parry L, Dilworth M, Renshall L, Brownfoot F, Hastie R, Tuohey L, Palmer K, Hirano T, Ikawa M, Kaitu'u-Lino T, Hannan NJ.

Hypertension. 2017 Mar;69(3):457-468. doi: 10.1161/HYPERTENSIONAHA.116.08408. Epub 2017 Jan 23. Erratum in: Hypertension. 2018 Apr;71(4):e11.

PMID:
28115513
38.

Epidermal Growth Factor Rescues Endothelial Dysfunction in Primary Human Tissues In Vitro.

Hastie R, Tong S, Hannan NJ, Brownfoot F, Cannon P, Kaitu'u-Lino TJ.

Reprod Sci. 2017 Sep;24(9):1245-1252. doi: 10.1177/1933719116681516. Epub 2016 Dec 5. Review.

PMID:
27920343
39.

Optimized inducible shRNA and CRISPR/Cas9 platforms for in vitro studies of human development using hPSCs.

Bertero A, Pawlowski M, Ortmann D, Snijders K, Yiangou L, Cardoso de Brito M, Brown S, Bernard WG, Cooper JD, Giacomelli E, Gambardella L, Hannan NR, Iyer D, Sampaziotis F, Serrano F, Zonneveld MC, Sinha S, Kotter M, Vallier L.

Development. 2016 Dec 1;143(23):4405-4418.

40.

Steroid sulfatase is increased in the placentas and whole blood of women with early-onset preeclampsia.

Gratton AM, Ye L, Brownfoot FC, Hannan NJ, Whitehead C, Cannon P, Deo M, Fuller PJ, Tong S, Kaitu'u-Lino TJ.

Placenta. 2016 Dec;48:72-79. doi: 10.1016/j.placenta.2016.10.008. Epub 2016 Oct 15.

PMID:
27871476
41.

Nuclear factor of activated T-cells (NFAT) regulates soluble fms-like tyrosine kinase-1 secretion (sFlt-1) from human placenta.

Ye L, Gratton A, Hannan NJ, Cannon P, Deo M, Palmer KR, Tong S, Kaitu'u-Lino TJ, Brownfoot FC.

Placenta. 2016 Dec;48:110-118. doi: 10.1016/j.placenta.2016.10.013. Epub 2016 Oct 21.

PMID:
27871461
42.

Placental Growth Factor Is Secreted by the Human Endometrium and Has Potential Important Functions during Embryo Development and Implantation.

Binder NK, Evans J, Salamonsen LA, Gardner DK, Kaitu'u-Lino TJ, Hannan NJ.

PLoS One. 2016 Oct 6;11(10):e0163096. doi: 10.1371/journal.pone.0163096. eCollection 2016.

43.

Derivation of Intestinal Organoids from Human Induced Pluripotent Stem Cells for Use as an Infection System.

Forbester JL, Hannan N, Vallier L, Dougan G.

Methods Mol Biol. 2016 Aug 31. [Epub ahead of print]

PMID:
27576565
44.

Abnormal plasma DNA profiles in early ovarian cancer using a non-invasive prenatal testing platform: implications for cancer screening.

Cohen PA, Flowers N, Tong S, Hannan N, Pertile MD, Hui L.

BMC Med. 2016 Aug 24;14(1):126. doi: 10.1186/s12916-016-0667-6.

45.

Evidence of proteinuria, but no other characteristics of pre-eclampsia, in relaxin-deficient mice.

O'Sullivan KP, Marshall SA, Cullen S, Saunders T, Hannan NJ, Senadheera SN, Parry LJ.

Reprod Fertil Dev. 2017 Aug;29(8):1477-1485. doi: 10.1071/RD16056.

PMID:
27489037
46.

A comparison of sample collection methods for quantifying cell-free fetal neurodevelopment transcripts in amniotic fluid.

Hui L, Tong S, Kaitu'u-Lino TJ, Hannan NJ.

BMC Res Notes. 2016 Jul 7;9:335. doi: 10.1186/s13104-016-2146-8.

47.
48.

Loss of Akt increases soluble endoglin release from endothelial cells but not placenta.

Kaitu'u-Lino TJ, Hastie R, Hannan NJ, Brownfoot F, De Silva M, Cannon P, Tuohey L, Tong S.

Pregnancy Hypertens. 2016 Apr;6(2):95-102. doi: 10.1016/j.preghy.2016.02.002. Epub 2016 Mar 28.

PMID:
27155335
49.

Identifying late-onset fetal growth restriction by measuring circulating placental RNA in the maternal blood at 28 weeks' gestation.

Whitehead CL, McNamara H, Walker SP, Alexiadis M, Fuller PJ, Vickers DK, Hannan NJ, Hastie R, Tuohey L, Kaitu'u-Lino TJ, Tong S.

Am J Obstet Gynecol. 2016 Apr;214(4):521.e1-521.e8. doi: 10.1016/j.ajog.2016.01.191. Epub 2016 Feb 12.

PMID:
26880734
50.

Jumonji Domain Containing Protein 6 Is Decreased in Human Preeclamptic Placentas and Regulates sFLT-1 Splice Variant Production.

Palmer KR, Tong S, Tuohey L, Cannon P, Ye L, Hannan NJ, Brownfoot FC, Illanes SE, Kaitu'u-Lino TJ.

Biol Reprod. 2016 Mar;94(3):59. doi: 10.1095/biolreprod.115.134460. Epub 2016 Jan 27.

PMID:
26819475

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