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Items: 1 to 50 of 85

1.

Fasciola gigantica: Ultrastructural cytochemistry of the tegumental surface in newly- excysted metacercariae and in vitro-penetrated juvenile flukes informs a concept of parasite defence at the interface with the host.

Hanna REB, Moffett D, Robinson MW, Jura WGZO, Brennan GP, Fairweather I, Threadgold LT.

Vet Parasitol. 2019 Oct;274:108923. doi: 10.1016/j.vetpar.2019.108923. Epub 2019 Sep 13.

PMID:
31542719
2.

Fasciola gigantica: Comparison of the tegumental ultrastructure in newly excysted metacercariae and in vitro penetrated juvenile flukes indicates intracellular sources of molecules with vaccinal and immunomodulatory potential.

Hanna REB, Moffett D, Robinson MW, Jura WGZO, Brennan GP, Fairweather I.

Vet Parasitol. 2019 Jan;265:38-47. doi: 10.1016/j.vetpar.2018.11.019. Epub 2018 Dec 7.

PMID:
30638519
3.

Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities.

Sanson KR, Hanna RE, Hegde M, Donovan KF, Strand C, Sullender ME, Vaimberg EW, Goodale A, Root DE, Piccioni F, Doench JG.

Nat Commun. 2018 Dec 21;9(1):5416. doi: 10.1038/s41467-018-07901-8.

4.

A case of mistaken identity.

Hanna RE, Doench JG.

Nat Biotechnol. 2018 Sep 6;36(9):802-804. doi: 10.1038/nbt.4208. No abstract available.

PMID:
30188534
5.

Seasonal variation of Fasciola hepatica antibodies in dairy herds in Northern Ireland measured by bulk tank milk ELISA.

Byrne AW, Graham J, McConville J, Milne G, McDowell S, Hanna REB, Guelbenzu-Gonzalo M.

Parasitol Res. 2018 Sep;117(9):2725-2733. doi: 10.1007/s00436-018-5961-0. Epub 2018 Jun 14.

PMID:
29948207
6.

Uncoupling of sgRNAs from their associated barcodes during PCR amplification of combinatorial CRISPR screens.

Hegde M, Strand C, Hanna RE, Doench JG.

PLoS One. 2018 May 25;13(5):e0197547. doi: 10.1371/journal.pone.0197547. eCollection 2018.

7.

Control of Nematodirus spp. infection by sheep flock owners in Northern Ireland.

McMahon C, Edgar HWJ, Barley JP, Hanna REB, Brennan GP, Fairweather I.

Ir Vet J. 2017 Oct 19;70:31. doi: 10.1186/s13620-017-0109-6. eCollection 2017.

8.

Disruption of egg production by triclabendazole-resistant Fasciola hepatica following treatment with a commercial preparation of myrrh (Mirazid).

Abdelaal MMO, Brennan GP, Hanna REB, Abdel-Aziz A, Fairweather I.

Acta Parasitol. 2017 Jun 1;62(2):336-347. doi: 10.1515/ap-2017-0041.

PMID:
28426420
9.

Tapeworm control practices by sheep farmers in Northern Ireland.

McMahon C, Edgar HWJ, Barley JP, Hanna REB, Brennan GP, Fairweather I.

Vet Parasitol Reg Stud Reports. 2017 Jan;7:14-18. doi: 10.1016/j.vprsr.2016.12.003. Epub 2016 Dec 7.

PMID:
31014650
10.

Fasciola hepatica: a light and electron microscope study of the ovary and of the development of oocytes within eggs in the uterus provides an insight into reproductive strategy.

Hanna RE, Moffett D, Forster FI, Trudgett AG, Brennan GP, Fairweather I.

Vet Parasitol. 2016 May 15;221:93-103. doi: 10.1016/j.vetpar.2016.03.011. Epub 2016 Mar 16.

PMID:
27084479
11.

Disruption of spermatogenesis in the liver fluke, Fasciola hepatica by two artemisinin derivatives, artemether and artesunate.

O'Neill JF, Johnston RC, Halferty L, Hanna RE, Brennan GP, Fairweather I.

J Helminthol. 2017 Jan;91(1):55-71. doi: 10.1017/S0022149X16000079. Epub 2016 Mar 16.

PMID:
26979164
12.

Liver fluke control on sheep farms in Northern Ireland: A survey of changing management practices in relation to disease prevalence and perceived triclabendazole resistance.

McMahon C, Edgar HW, Hanna RE, Ellison SE, Flanagan AM, McCoy M, Kajugu PE, Gordon AW, Irwin D, Barley JE, Malone FE, Brennan GP, Fairweather I.

Vet Parasitol. 2016 Jan 30;216:72-83. doi: 10.1016/j.vetpar.2015.11.018. Epub 2015 Dec 12.

PMID:
26801598
13.

Fasciola hepatica: Histological changes in the somatic and reproductive tissues of liver fluke following closantel treatment of experimentally-infected sheep.

Scarcella S, Hanna RE, Brennan GP, Solana H, Fairweather I.

Vet Parasitol. 2016 Jan 15;215:38-47. doi: 10.1016/j.vetpar.2015.10.029. Epub 2015 Nov 10.

PMID:
26790736
14.

Fasciola hepatica: Specificity of a coproantigen ELISA test for diagnosis of fasciolosis in faecal samples from cattle and sheep concurrently infected with gastrointestinal nematodes, coccidians and/or rumen flukes (paramphistomes), under field conditions.

Kajugu PE, Hanna RE, Edgar HW, McMahon C, Cooper M, Gordon A, Barley JP, Malone FE, Brennan GP, Fairweather I.

Vet Parasitol. 2015 Sep 15;212(3-4):181-7. doi: 10.1016/j.vetpar.2015.07.018. Epub 2015 Jul 23.

PMID:
26234898
15.

A comparative study on the impact of two artemisinin derivatives, artemether and artesunate, on the female reproductive system of Fasciola hepatica.

O'Neill JF, Johnston RC, Halferty L, Hanna RE, Brennan GP, Fairweather I.

Vet Parasitol. 2015 Jul 30;211(3-4):182-94. doi: 10.1016/j.vetpar.2015.05.027. Epub 2015 Jun 6.

PMID:
26093822
16.

Fasciola hepatica: a comparative survey of adult fluke resistance to triclabendazole, nitroxynil and closantel on selected upland and lowland sheep farms in Northern Ireland using faecal egg counting, coproantigen ELISA testing and fluke histology.

Hanna RE, McMahon C, Ellison S, Edgar HW, Kajugu PE, Gordon A, Irwin D, Barley JP, Malone FE, Brennan GP, Fairweather I.

Vet Parasitol. 2015 Jan 15;207(1-2):34-43. doi: 10.1016/j.vetpar.2014.11.016. Epub 2014 Nov 24.

PMID:
25529143
17.

Bovine paramphistomes in Ireland.

Zintl A, Garcia-Campos A, Trudgett A, Chryssafidis AL, Talavera-Arce S, Fu Y, Egan S, Lawlor A, Negredo C, Brennan G, Hanna RE, De Waal T, Mulcahy G.

Vet Parasitol. 2014 Aug 29;204(3-4):199-208. doi: 10.1016/j.vetpar.2014.05.024. Epub 2014 May 23.

PMID:
24907069
18.

Anthelmintic resistance in Northern Ireland (I): prevalence of resistance in ovine gastrointestinal nematodes, as determined through faecal egg count reduction testing.

McMahon C, Bartley DJ, Edgar HW, Ellison SE, Barley JP, Malone FE, Hanna RE, Brennan GP, Fairweather I.

Vet Parasitol. 2013 Jul 1;195(1-2):122-30. doi: 10.1016/j.vetpar.2013.01.006. Epub 2013 Jan 21.

PMID:
23398988
19.

Anthelmintic resistance in Northern Ireland (III): uptake of 'SCOPS' (Sustainable Control of Parasites in Sheep) recommendations by sheep farmers.

McMahon C, McCoy M, Ellison SE, Barley JP, Edgar HW, Hanna RE, Malone FE, Brennan GP, Fairweather I.

Vet Parasitol. 2013 Mar 31;193(1-3):179-84. doi: 10.1016/j.vetpar.2012.11.032. Epub 2012 Dec 5.

PMID:
23273780
20.

Anthelmintic resistance in Northern Ireland. II: Variations in nematode control practices between lowland and upland sheep flocks.

McMahon C, Barley JP, Edgar HW, Ellison SE, Hanna RE, Malone FE, Brennan GP, Fairweather I.

Vet Parasitol. 2013 Feb 18;192(1-3):173-82. doi: 10.1016/j.vetpar.2012.10.022. Epub 2012 Nov 11.

PMID:
23228496
21.

Substantial genetic divergence between morphologically indistinguishable populations of Fasciola suggests the possibility of cryptic speciation.

Walker SM, Prodöhl PA, Hoey EM, Fairweather I, Hanna RE, Brennan G, Trudgett A.

Int J Parasitol. 2012 Dec;42(13-14):1193-9. doi: 10.1016/j.ijpara.2012.10.007. Epub 2012 Nov 3.

PMID:
23131680
22.

Specificity of a coproantigen ELISA test for fasciolosis: lack of cross-reactivity with Paramphistomum cervi and Taenia hydatigena.

Kajugu PE, Hanna RE, Edgar HW, Forster FI, Malone FE, Brennan GP, Fairweather I.

Vet Rec. 2012 Nov 17;171(20):502. doi: 10.1136/vr.101041. Epub 2012 Oct 17.

PMID:
23077134
24.

The effects of climate change on ovine parasitic gastroenteritis determined using veterinary surveillance and meteorological data for Northern Ireland over the period 1999-2009.

McMahon C, Gordon AW, Edgar HW, Hanna RE, Brennan GP, Fairweather I.

Vet Parasitol. 2012 Nov 23;190(1-2):167-77. doi: 10.1016/j.vetpar.2012.06.016. Epub 2012 Jun 23.

PMID:
22789298
25.

Impact of compound alpha treatment in vivo on egg production by the liver fluke, Fasciola hepatica.

McConville M, Hanna RE, Brennan GP, Edgar HW, McConnell S, McCoy M, Castillo R, Hernández-Campos A, Fairweather I.

Vet Parasitol. 2012 Jun 8;187(1-2):183-95. doi: 10.1016/j.vetpar.2011.12.028. Epub 2011 Dec 28.

PMID:
22285009
26.

Fasciola hepatica: a light and electron microscope study of sustentacular tissue and heterophagy in the testis.

Hanna RE, Moffett D, Brennan GP, Fairweather I.

Vet Parasitol. 2012 Jun 8;187(1-2):168-82. doi: 10.1016/j.vetpar.2011.12.037. Epub 2012 Jan 5.

PMID:
22281149
27.

Early onset of changes to the reproductive system of Fasciola hepatica following in vivo treatment with triclabendazole.

Hanna RE, Scarcella S, Solana H, McConnell S, Fairweather I.

Vet Parasitol. 2012 Mar 23;184(2-4):341-7. doi: 10.1016/j.vetpar.2011.08.023. Epub 2011 Aug 19.

PMID:
21944196
28.

Fasciola hepatica: time-dependent disruption of spermatogenesis following in vivo treatment with triclabendazole.

Toner E, Brennan GP, Hanna RE, Edgar HW, Fairweather I.

Parasitol Res. 2011 Oct;109(4):1035-43. doi: 10.1007/s00436-011-2341-4. Epub 2011 May 4.

PMID:
21541756
29.

Fasciola hepatica: comparative effects of host resistance and parasite intra-specific interactions on size and reproductive histology in flukes from rats infected with isolates differing in triclabendazole sensitivity.

Hanna RE, Gordon AW, Moffett D, Edgar HW, Oliver LF, McConnell S, Shaw L, Brennan GP, Fairweather I.

Vet Parasitol. 2011 Jun 10;178(3-4):251-63. doi: 10.1016/j.vetpar.2011.01.045. Epub 2011 Feb 1.

PMID:
21333449
30.

Reproductive disruption in Fasciola hepatica associated with incomplete efficacy of a new experimental formulation of triclabendazole.

Scarcella S, Fiel C, Guzman M, Alzola R, Felipe A, Hanna RE, Fairweather I, McConnell S, Solana H.

Vet Parasitol. 2011 Mar 10;176(2-3):157-64. doi: 10.1016/j.vetpar.2010.11.009. Epub 2010 Nov 19.

PMID:
21167645
31.

Disruption of egg formation by Fasciola hepatica following treatment in vivo with triclabendazole in the sheep host.

Toner E, Brennan GP, Hanna RE, Edgar HW, Fairweather I.

Vet Parasitol. 2011 Apr 19;177(1-2):79-89. doi: 10.1016/j.vetpar.2010.11.032. Epub 2010 Nov 25.

PMID:
21163580
32.

Comparison of two assays, a faecal egg count reduction test (FECRT) and a coproantigen reduction test (CRT), for the diagnosis of resistance to triclabendazole in Fasciola hepatica in sheep.

Flanagan A, Edgar HW, Gordon A, Hanna RE, Brennan GP, Fairweather I.

Vet Parasitol. 2011 Mar 10;176(2-3):170-6. doi: 10.1016/j.vetpar.2010.10.057. Epub 2010 Nov 5.

PMID:
21112153
33.

Standardisation of a coproantigen reduction test (CRT) protocol for the diagnosis of resistance to triclabendazole in Fasciola hepatica.

Flanagan AM, Edgar HW, Forster F, Gordon A, Hanna RE, McCoy M, Brennan GP, Fairweather I.

Vet Parasitol. 2011 Feb 28;176(1):34-42. doi: 10.1016/j.vetpar.2010.10.037. Epub 2010 Oct 27.

PMID:
21093156
34.

Time-dependent changes to the tegumental system and gastrodermis of adult Fasciola hepatica following treatment in vivo with triclabendazole in the sheep host.

Toner E, Brennan GP, Hanna RE, Edgar HW, Fairweather I.

Vet Parasitol. 2010 Dec 15;174(3-4):218-27. doi: 10.1016/j.vetpar.2010.09.008. Epub 2010 Sep 16.

PMID:
20933333
35.

Tegumental surface changes in adult Fasciola hepatica in response to treatment in vivo with triclabendazole in the sheep host.

Toner E, Brennan GP, Hanna RE, Edgar HW, Fairweather I.

Vet Parasitol. 2010 Sep 20;172(3-4):238-48. doi: 10.1016/j.vetpar.2010.05.012. Epub 2010 May 16.

PMID:
20627418
36.

Fasciola hepatica: histological changes in the reproductive structures of triclabendazole (TCBZ)-sensitive and TCBZ-resistant flukes after treatment in vivo with TCBZ and the related benzimidazole derivative, Compound Alpha.

Hanna RE, Edgar HW, McConnell S, Toner E, McConville M, Brennan GP, Devine C, Flanagan A, Halferty L, Meaney M, Shaw L, Moffett D, McCoy M, Fairweather I.

Vet Parasitol. 2010 Mar 25;168(3-4):240-54. doi: 10.1016/j.vetpar.2009.11.014. Epub 2009 Nov 27.

PMID:
20053501
37.

Fasciola hepatica: disruption of spermatogenesis by the fasciolicide compound alpha.

McConville M, Hanna RE, Brennan GP, McCoy M, Edgar HW, McConnell S, Castillo R, Hernández-Campos A, Fairweather I.

Parasitol Res. 2010 Jan;106(2):311-23. doi: 10.1007/s00436-009-1649-9. Epub 2009 Nov 18.

PMID:
19921260
38.

Surface changes in adult Fasciola hepatica following treatment in vivo with the experimental fasciolicide, compound alpha.

McConville M, Brennan GP, Flanagan A, Hanna RE, Edgar HW, Castillo R, Hernández-Campos A, Fairweather I.

Parasitol Res. 2009 Sep;105(3):757-67. doi: 10.1007/s00436-009-1453-6. Epub 2009 May 21.

PMID:
19458965
39.

An evaluation of the efficacy of compound alpha and triclabendazole against two isolates of Fasciola hepatica.

McConville M, Brennan GP, Flanagan A, Edgar HW, Hanna RE, McCoy M, Gordon AW, Castillo R, Hernández-Campos A, Fairweather I.

Vet Parasitol. 2009 May 26;162(1-2):75-88. doi: 10.1016/j.vetpar.2009.02.004. Epub 2009 Feb 12.

PMID:
19282108
40.

Fasciola hepatica: Histology of the testis in egg-producing adults of several laboratory-maintained isolates of flukes grown to maturity in cattle and sheep and in flukes from naturally infected hosts.

Hanna RE, Edgar H, Moffett D, McConnell S, Fairweather I, Brennan GP, Trudgett A, Hoey EM, Cromie L, Taylor SM, Daniel R.

Vet Parasitol. 2008 Nov 7;157(3-4):222-34. doi: 10.1016/j.vetpar.2008.07.022. Epub 2008 Jul 26.

PMID:
18774647
41.

Tegumental surface changes in juvenile Fasciola hepatica in response to treatment in vivo with triclabendazole.

Halferty L, Brennan GP, Hanna RE, Edgar HW, Meaney MM, McConville M, Trudgett A, Hoey L, Fairweather I.

Vet Parasitol. 2008 Aug 1;155(1-2):49-58. doi: 10.1016/j.vetpar.2008.04.011. Epub 2008 Apr 22.

PMID:
18511199
42.

Evidence for multiple mitochondrial lineages of Fasciola hepatica (liver fluke) within infrapopulations from cattle and sheep.

Walker SM, Prodöhl PA, Fletcher HL, Hanna RE, Kantzoura V, Hoey EM, Trudgett A.

Parasitol Res. 2007 Jun;101(1):117-25. Epub 2007 Jan 11.

PMID:
17216485
43.

The effect of a parenteral ivermectin/closantel injection on the growth and reproductive development of early immature Fasciola hepatica in cattle.

Hanna RE, Cromie L, Taylor SM, Couper A.

Vet Parasitol. 2006 Nov 30;142(1-2):78-90. Epub 2006 Aug 9.

PMID:
16901648
44.

Ultrastructure of the male reproductive system in a rumen amphistome Cotylophoron cotylophorum.

Sharma PN, Swarnakar G, Hanna RE.

J Helminthol. 1994 Sep;68(3):255-8.

PMID:
7829847
45.
46.

Serotoninergic and peptidergic nerve elements in the protoscolex of Echinococcus granulosus (Cestoda, Cyclophyllidea).

Fairweather I, McMullan MT, Johnston CF, Rogan MT, Hanna RE.

Parasitol Res. 1994;80(8):649-56.

PMID:
7533908
50.

Ultrastructural observations on the redial tegument of Paramphistomum epiclitum from the planorbid snail, Indoplanorbis exustus.

Dunn TS, Dang PH, Mattison G, Hanna RE, Nizami WA.

J Helminthol. 1992 Sep;66(3):167-76.

PMID:
1452991

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