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Items: 1 to 50 of 54

1.

MB0 and MBI Are Independent and Distinct Transactivation Domains in MYC that Are Essential for Transformation.

Zhang Q, West-Osterfield K, Spears E, Li Z, Panaccione A, Hann SR.

Genes (Basel). 2017 May 6;8(5). pii: E134. doi: 10.3390/genes8050134.

2.

Small-molecule high-throughput screening utilizing Xenopus egg extract.

Broadus MR, Yew PR, Hann SR, Lee E.

Methods Mol Biol. 2015;1263:63-73. doi: 10.1007/978-1-4939-2269-7_5.

3.

Targeting nucleophosmin 1 represents a rational strategy for radiation sensitization.

Sekhar KR, Benamar M, Venkateswaran A, Sasi S, Penthala NR, Crooks PA, Hann SR, Geng L, Balusu R, Abbas T, Freeman ML.

Int J Radiat Oncol Biol Phys. 2014 Aug 1;89(5):1106-1114. doi: 10.1016/j.ijrobp.2014.04.012. Epub 2014 Jul 8.

4.

MYC cofactors: molecular switches controlling diverse biological outcomes.

Hann SR.

Cold Spring Harb Perspect Med. 2014 Jun 17;4(9):a014399. doi: 10.1101/cshperspect.a014399. Review.

5.

Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity.

Zhang Q, Spears E, Boone DN, Li Z, Gregory MA, Hann SR.

Proc Natl Acad Sci U S A. 2013 Jan 15;110(3):978-83. doi: 10.1073/pnas.1208334110. Epub 2012 Dec 31.

6.

Thr 163 phosphorylation causes Mcl-1 stabilization when degradation is independent of the adjacent GSK3-targeted phosphodegron, promoting drug resistance in cancer.

Nifoussi SK, Vrana JA, Domina AM, De Biasio A, Gui J, Gregory MA, Hann SR, Craig RW.

PLoS One. 2012;7(10):e47060. doi: 10.1371/journal.pone.0047060. Epub 2012 Oct 9.

7.

Nucleophosmin is essential for c-Myc nucleolar localization and c-Myc-mediated rDNA transcription.

Li Z, Hann SR.

Oncogene. 2013 Apr 11;32(15):1988-94. doi: 10.1038/onc.2012.227. Epub 2012 Jun 4.

8.

The Myc-ARF-Egr1 pathway: unleashing the apoptotic power of c-Myc.

Boone DN, Hann SR.

Cell Cycle. 2011 Jul 1;10(13):2043-4. No abstract available.

9.

Egr1 mediates p53-independent c-Myc-induced apoptosis via a noncanonical ARF-dependent transcriptional mechanism.

Boone DN, Qi Y, Li Z, Hann SR.

Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):632-7. doi: 10.1073/pnas.1008848108. Epub 2010 Dec 27.

10.

The Myc-nucleophosmin-ARF network: a complex web unveiled.

Li Z, Hann SR.

Cell Cycle. 2009 Sep 1;8(17):2703-7. Epub 2009 Sep 2. Review.

11.

Nucleophosmin interacts directly with c-Myc and controls c-Myc-induced hyperproliferation and transformation.

Li Z, Boone D, Hann SR.

Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18794-9. doi: 10.1073/pnas.0806879105. Epub 2008 Nov 24.

12.

c-Myc represses FOXO3a-mediated transcription of the gene encoding the p27(Kip1) cyclin dependent kinase inhibitor.

Chandramohan V, Mineva ND, Burke B, Jeay S, Wu M, Shen J, Yang W, Hann SR, Sonenshein GE.

J Cell Biochem. 2008 Aug 15;104(6):2091-106. doi: 10.1002/jcb.21765.

PMID:
18393360
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The alpha1 subunit of GABAA receptor is repressed by c-myc and is pro-apoptotic.

Vaknin UA, Hann SR.

J Cell Biochem. 2006 Apr 1;97(5):1094-103.

PMID:
16294320
16.

The ARF tumor suppressor: keeping Myc on a leash.

Gregory MA, Qi Y, Hann SR.

Cell Cycle. 2005 Feb;4(2):249-52. Epub 2005 Feb 21.

PMID:
15655352
17.

p19ARF directly and differentially controls the functions of c-Myc independently of p53.

Qi Y, Gregory MA, Li Z, Brousal JP, West K, Hann SR.

Nature. 2004 Oct 7;431(7009):712-7. Epub 2004 Sep 8.

PMID:
15361884
18.
19.

Phosphorylation by glycogen synthase kinase-3 controls c-myc proteolysis and subnuclear localization.

Gregory MA, Qi Y, Hann SR.

J Biol Chem. 2003 Dec 19;278(51):51606-12. Epub 2003 Oct 16.

20.

B-Myc, a proximal caput epididymal protein, is dependent on androgens and testicular factors for expression.

Cornwall GA, Collis R, Xiao Q, Hsia N, Hann SR.

Biol Reprod. 2001 Jun;64(6):1600-7.

PMID:
11369584
21.

B-Myc is preferentially expressed in hormonally-controlled tissues and inhibits cellular proliferation.

Gregory MA, Xiao Q, Cornwall GA, Lutterbach B, Hann SR.

Oncogene. 2000 Oct 5;19(42):4886-95.

22.
23.

Disruption of Myc-tubulin interaction by hyperphosphorylation of c-Myc during mitosis or by constitutive hyperphosphorylation of mutant c-Myc in Burkitt's lymphoma.

Niklinski J, Claassen G, Meyers C, Gregory MA, Allegra CJ, Kaye FJ, Hann SR, Zajac-Kaye M.

Mol Cell Biol. 2000 Jul;20(14):5276-84.

24.

The c-Myc transactivation domain is a direct modulator of apoptotic versus proliferative signals.

Chang DW, Claassen GF, Hann SR, Cole MD.

Mol Cell Biol. 2000 Jun;20(12):4309-19.

25.
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Myc-mediated transformation: the repression connection.

Claassen GF, Hann SR.

Oncogene. 1999 May 13;18(19):2925-33. Review.

27.
28.

Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation.

Greenberg RA, O'Hagan RC, Deng H, Xiao Q, Hann SR, Adams RR, Lichtsteiner S, Chin L, Morin GB, DePinho RA.

Oncogene. 1999 Feb 4;18(5):1219-26.

29.

Transactivation-defective c-MycS retains the ability to regulate proliferation and apoptosis.

Xiao Q, Claassen G, Shi J, Adachi S, Sedivy J, Hann SR.

Genes Dev. 1998 Dec 15;12(24):3803-8.

31.

Overexpression of c-Myc and cell immortalization alters c-Myc phosphorylation.

Lutterbach B, Hann SR.

Oncogene. 1997 Feb 27;14(8):967-75.

32.

Variant Max protein, derived by alternative splicing, associates with c-Myc in vivo and inhibits transactivation.

Arsura M, Deshpande A, Hann SR, Sonenshein GE.

Mol Cell Biol. 1995 Dec;15(12):6702-9.

33.

Specialized gene expression in the epididymis.

Cornwall GA, Hann SR.

J Androl. 1995 Sep-Oct;16(5):379-83. Review. No abstract available.

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39.

Regulation and function of non-AUG-initiated proto-oncogenes.

Hann SR.

Biochimie. 1994;76(9):880-6. Review.

PMID:
7880905
40.
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45.

Antisense inhibition of c-myc expression reveals common and distinct mechanisms of growth inhibition by TGF beta and TNF alpha.

Robinson-Benion C, Salhany KE, Hann SR, Holt JT.

J Cell Biochem. 1991 Feb;45(2):188-95.

PMID:
2055946
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49.

Proteins expressed by the c-myc oncogene in lymphomas of human and avian origin.

Eisenman RN, Hann SR.

Proc R Soc Lond B Biol Sci. 1985 Oct 22;226(1242):73-8.

PMID:
2866525
50.

c-myc oncogene protein synthesis is independent of the cell cycle in human and avian cells.

Hann SR, Thompson CB, Eisenman RN.

Nature. 1985 Mar 28-Apr 3;314(6009):366-9.

PMID:
3885045

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