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Items: 1 to 50 of 107

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2,3,7,8‑Tetrachlorodibenzo‑p‑dioxin suppresses the growth of human liver cancer HepG2 cells in vitro: Involvement of cell signaling factors.

Yamaguchi M, Hankinson O.

Int J Oncol. 2018 Oct;53(4):1657-1666. doi: 10.3892/ijo.2018.4507. Epub 2018 Jul 27.

5.

ChIP-re-ChIP: Co-occupancy Analysis by Sequential Chromatin Immunoprecipitation.

Beischlag TV, Prefontaine GG, Hankinson O.

Methods Mol Biol. 2018;1689:103-112. doi: 10.1007/978-1-4939-7380-4_9.

PMID:
29027168
6.

The role of AHR-inducible cytochrome P450s in metabolism of polyunsaturated fatty acids.

Hankinson O.

Drug Metab Rev. 2016 Aug;48(3):342-50. doi: 10.1080/03602532.2016.1197240. Epub 2016 Jun 30. Review.

7.

Role of diets rich in omega-3 and omega-6 in the development of cancer.

Huerta-Yépez S, Tirado-Rodriguez AB, Hankinson O.

Bol Med Hosp Infant Mex. 2016 Nov - Dec;73(6):446-456. doi: 10.1016/j.bmhimx.2016.11.001. Epub 2016 Nov 30. Review.

8.

SIN3A, generally regarded as a transcriptional repressor, is required for induction of gene transcription by the aryl hydrocarbon receptor.

Solaimani P, Wang F, Hankinson O.

J Biol Chem. 2014 Nov 28;289(48):33655-62. doi: 10.1074/jbc.M114.611236. Epub 2014 Oct 10.

10.

Genome-wide RNAi high-throughput screen identifies proteins necessary for the AHR-dependent induction of CYP1A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Solaimani P, Damoiseaux R, Hankinson O.

Toxicol Sci. 2013 Nov;136(1):107-19. doi: 10.1093/toxsci/kft191. Epub 2013 Aug 31.

11.

Potential role of epigenetic mechanisms in the regulation of drug metabolism and transport.

Ingelman-Sundberg M, Zhong XB, Hankinson O, Beedanagari S, Yu AM, Peng L, Osawa Y.

Drug Metab Dispos. 2013 Oct;41(10):1725-31. doi: 10.1124/dmd.113.053157. Epub 2013 Aug 5.

12.

HIF-1 expression is associated with CCL2 chemokine expression in airway inflammatory cells: implications in allergic airway inflammation.

Baay-Guzman GJ, Bebenek IG, Zeidler M, Hernandez-Pando R, Vega MI, Garcia-Zepeda EA, Antonio-Andres G, Bonavida B, Riedl M, Kleerup E, Tashkin DP, Hankinson O, Huerta-Yepez S.

Respir Res. 2012 Jul 23;13:60. doi: 10.1186/1465-9921-13-60.

13.

The transcription factor encyclopedia.

Yusuf D, Butland SL, Swanson MI, Bolotin E, Ticoll A, Cheung WA, Zhang XY, Dickman CT, Fulton DL, Lim JS, Schnabl JM, Ramos OH, Vasseur-Cognet M, de Leeuw CN, Simpson EM, Ryffel GU, Lam EW, Kist R, Wilson MS, Marco-Ferreres R, Brosens JJ, Beccari LL, Bovolenta P, Benayoun BA, Monteiro LJ, Schwenen HD, Grontved L, Wederell E, Mandrup S, Veitia RA, Chakravarthy H, Hoodless PA, Mancarelli MM, Torbett BE, Banham AH, Reddy SP, Cullum RL, Liedtke M, Tschan MP, Vaz M, Rizzino A, Zannini M, Frietze S, Farnham PJ, Eijkelenboom A, Brown PJ, Laperrière D, Leprince D, de Cristofaro T, Prince KL, Putker M, del Peso L, Camenisch G, Wenger RH, Mikula M, Rozendaal M, Mader S, Ostrowski J, Rhodes SJ, Van Rechem C, Boulay G, Olechnowicz SW, Breslin MB, Lan MS, Nanan KK, Wegner M, Hou J, Mullen RD, Colvin SC, Noy PJ, Webb CF, Witek ME, Ferrell S, Daniel JM, Park J, Waldman SA, Peet DJ, Taggart M, Jayaraman PS, Karrich JJ, Blom B, Vesuna F, O'Geen H, Sun Y, Gronostajski RM, Woodcroft MW, Hough MR, Chen E, Europe-Finner GN, Karolczak-Bayatti M, Bailey J, Hankinson O, Raman V, LeBrun DP, Biswal S, Harvey CJ, DeBruyne JP, Hogenesch JB, Hevner RF, Héligon C, Luo XM, Blank MC, Millen KJ, Sharlin DS, Forrest D, Dahlman-Wright K, Zhao C, Mishima Y, Sinha S, Chakrabarti R, Portales-Casamar E, Sladek FM, Bradley PH, Wasserman WW.

Genome Biol. 2012;13(3):R24. doi: 10.1186/gb-2012-13-3-r24.

14.

2,3,7,8-Tetrachlorodibenzo-p-dioxin treatment alters eicosanoid levels in several organs of the mouse in an aryl hydrocarbon receptor-dependent fashion.

Bui P, Solaimani P, Wu X, Hankinson O.

Toxicol Appl Pharmacol. 2012 Mar 1;259(2):143-51. doi: 10.1016/j.taap.2011.12.009. Epub 2011 Dec 20.

15.

CYP2S1 is negatively regulated by corticosteroids in human cell lines.

Bebenek IG, Solaimani P, Bui P, Hankinson O.

Toxicol Lett. 2012 Feb 25;209(1):30-4. doi: 10.1016/j.toxlet.2011.11.020. Epub 2011 Nov 30.

PMID:
22155357
16.

Hypoxia inducible factor promotes murine allergic airway inflammation and is increased in asthma and rhinitis.

Huerta-Yepez S, Baay-Guzman GJ, Bebenek IG, Hernandez-Pando R, Vega MI, Chi L, Riedl M, Diaz-Sanchez D, Kleerup E, Tashkin DP, Gonzalez FJ, Bonavida B, Zeidler M, Hankinson O.

Allergy. 2011 Jul;66(7):909-18. doi: 10.1111/j.1398-9995.2011.02594.x. Epub 2011 Apr 26.

17.

Comparison of mibefradil and derivative NNC 55-0396 effects on behavior, cytochrome P450 activity, and tremor in mouse models of essential tremor.

Quesada A, Bui PH, Homanics GE, Hankinson O, Handforth A.

Eur J Pharmacol. 2011 May 20;659(1):30-6. doi: 10.1016/j.ejphar.2011.01.004. Epub 2011 Jan 21.

18.

Human CYP2S1 metabolizes cyclooxygenase- and lipoxygenase-derived eicosanoids.

Bui P, Imaizumi S, Beedanagari SR, Reddy ST, Hankinson O.

Drug Metab Dispos. 2011 Feb;39(2):180-90. doi: 10.1124/dmd.110.035121. Epub 2010 Nov 10.

19.

Role of epigenetic mechanisms in differential regulation of the dioxin-inducible human CYP1A1 and CYP1B1 genes.

Beedanagari SR, Taylor RT, Bui P, Wang F, Nickerson DW, Hankinson O.

Mol Pharmacol. 2010 Oct;78(4):608-16. doi: 10.1124/mol.110.064899. Epub 2010 Jul 14.

20.

Roles of coactivators in hypoxic induction of the erythropoietin gene.

Wang F, Zhang R, Wu X, Hankinson O.

PLoS One. 2010 Apr 2;5(4):e10002. doi: 10.1371/journal.pone.0010002.

21.

Differential regulation of the dioxin-induced Cyp1a1 and Cyp1b1 genes in mouse hepatoma and fibroblast cell lines.

Beedanagari SR, Taylor RT, Hankinson O.

Toxicol Lett. 2010 Apr 15;194(1-2):26-33. doi: 10.1016/j.toxlet.2010.01.019. Epub 2010 Jan 29.

22.

Aryl hydrocarbon nuclear translocator (hypoxia inducible factor 1beta) activity is required more during early than late tumor growth.

Shi S, Yoon DY, Hodge-Bell K, Huerta-Yepez S, Hankinson O.

Mol Carcinog. 2010 Feb;49(2):157-65. doi: 10.1002/mc.20585.

23.

The aryl hydrocarbon receptor nuclear translocator (Arnt) is required for tumor initiation by benzo[a]pyrene.

Shi S, Yoon DY, Hodge-Bell KC, Bebenek IG, Whitekus MJ, Zhang R, Cochran AJ, Huerta-Yepez S, Yim SH, Gonzalez FJ, Jaiswal AK, Hankinson O.

Carcinogenesis. 2009 Nov;30(11):1957-61. doi: 10.1093/carcin/bgp201. Epub 2009 Sep 15.

24.

Functional characterization of human cytochrome P450 2S1 using a synthetic gene-expressed protein in Escherichia coli.

Bui PH, Hankinson O.

Mol Pharmacol. 2009 Nov;76(5):1031-43. doi: 10.1124/mol.109.057752. Epub 2009 Aug 27.

25.

Fatty acid hydroperoxides support cytochrome P450 2S1-mediated bioactivation of benzo[a]pyrene-7,8-dihydrodiol.

Bui PH, Hsu EL, Hankinson O.

Mol Pharmacol. 2009 Nov;76(5):1044-52. doi: 10.1124/mol.109.057760. Epub 2009 Aug 27.

26.

Repression of aryl hydrocarbon receptor transcriptional activity by epidermal growth factor.

Hankinson O.

Mol Interv. 2009 Jun;9(3):116-8. doi: 10.1124/mi.9.3.4.

27.

Resveratrol inhibits dioxin-induced expression of human CYP1A1 and CYP1B1 by inhibiting recruitment of the aryl hydrocarbon receptor complex and RNA polymerase II to the regulatory regions of the corresponding genes.

Beedanagari SR, Bebenek I, Bui P, Hankinson O.

Toxicol Sci. 2009 Jul;110(1):61-7. doi: 10.1093/toxsci/kfp079. Epub 2009 Apr 17. Erratum in: Toxicol Sci. 2010 Aug;116(2):693.

28.

Modulation of CXCR4, CXCL12, and Tumor Cell Invasion Potential In Vitro by Phytochemicals.

Hsu EL, Chen N, Westbrook A, Wang F, Zhang R, Taylor RT, Hankinson O.

J Oncol. 2009;2009:491985. doi: 10.1155/2009/491985. Epub 2009 Mar 24.

29.

Transcriptional regulation of urokinase-type plasminogen activator receptor by hypoxia-inducible factor 1 is crucial for invasion of pancreatic and liver cancer.

Büchler P, Reber HA, Tomlinson JS, Hankinson O, Kallifatidis G, Friess H, Herr I, Hines OJ.

Neoplasia. 2009 Feb;11(2):196-206.

30.

Roles of coactivator proteins in dioxin induction of CYP1A1 and CYP1B1 in human breast cancer cells.

Taylor RT, Wang F, Hsu EL, Hankinson O.

Toxicol Sci. 2009 Jan;107(1):1-8. doi: 10.1093/toxsci/kfn217. Epub 2008 Oct 8.

31.

The mibefradil derivative NNC55-0396, a specific T-type calcium channel antagonist, exhibits less CYP3A4 inhibition than mibefradil.

Bui PH, Quesada A, Handforth A, Hankinson O.

Drug Metab Dispos. 2008 Jul;36(7):1291-9. doi: 10.1124/dmd.107.020115. Epub 2008 Apr 14.

32.

Why does ARNT2 behave differently from ARNT?

Hankinson O.

Toxicol Sci. 2008 May;103(1):1-3. doi: 10.1093/toxsci/kfn032. No abstract available.

33.

CXCR4 and CXCL12 down-regulation: a novel mechanism for the chemoprotection of 3,3'-diindolylmethane for breast and ovarian cancers.

Hsu EL, Chen N, Westbrook A, Wang F, Zhang R, Taylor RT, Hankinson O.

Cancer Lett. 2008 Jun 28;265(1):113-23. doi: 10.1016/j.canlet.2008.02.033. Epub 2008 Apr 2.

PMID:
18378071
34.

Inhibitory effects of nitric oxide on invasion of human cancer cells.

Wang F, Zhang R, Xia T, Hsu E, Cai Y, Gu Z, Hankinson O.

Cancer Lett. 2007 Nov 18;257(2):274-82. Epub 2007 Sep 14.

35.

Identification of novel dioxin-responsive genes by representational difference analysis.

Rivera SP, Saarikoski ST, Sun W, Hankinson O.

Xenobiotica. 2007 Mar;37(3):271-9.

PMID:
17624025
36.

A proposed mechanism for the protective effect of dioxin against breast cancer.

Hsu EL, Yoon D, Choi HH, Wang F, Taylor RT, Chen N, Zhang R, Hankinson O.

Toxicol Sci. 2007 Aug;98(2):436-44. Epub 2007 May 21.

PMID:
17517823
37.

A novel promoter element containing multiple overlapping xenobiotic and hypoxia response elements mediates induction of cytochrome P4502S1 by both dioxin and hypoxia.

Rivera SP, Wang F, Saarikoski ST, Taylor RT, Chapman B, Zhang R, Hankinson O.

J Biol Chem. 2007 Apr 13;282(15):10881-93. Epub 2007 Feb 2.

38.
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CYP2S1: a short review.

Saarikoski ST, Rivera SP, Hankinson O, Husgafvel-Pursiainen K.

Toxicol Appl Pharmacol. 2005 Sep 1;207(2 Suppl):62-9. Review.

PMID:
16054184
41.

Identification of aldehyde oxidase 1 and aldehyde oxidase homologue 1 as dioxin-inducible genes.

Rivera SP, Choi HH, Chapman B, Whitekus MJ, Terao M, Garattini E, Hankinson O.

Toxicology. 2005 Feb 28;207(3):401-9.

PMID:
15664268
42.

Role of coactivators in transcriptional activation by the aryl hydrocarbon receptor.

Hankinson O.

Arch Biochem Biophys. 2005 Jan 15;433(2):379-86. Review.

PMID:
15581594
44.

Recruitment of thyroid hormone receptor/retinoblastoma-interacting protein 230 by the aryl hydrocarbon receptor nuclear translocator is required for the transcriptional response to both dioxin and hypoxia.

Beischlag TV, Taylor RT, Rose DW, Yoon D, Chen Y, Lee WH, Rosenfeld MG, Hankinson O.

J Biol Chem. 2004 Dec 24;279(52):54620-8. Epub 2004 Oct 13.

45.

Roles of Brahma and Brahma/SWI2-related gene 1 in hypoxic induction of the erythropoietin gene.

Wang F, Zhang R, Beischlag TV, Muchardt C, Yaniv M, Hankinson O.

J Biol Chem. 2004 Nov 5;279(45):46733-41. Epub 2004 Sep 3.

46.

Role of mediator in transcriptional activation by the aryl hydrocarbon receptor.

Wang S, Ge K, Roeder RG, Hankinson O.

J Biol Chem. 2004 Apr 2;279(14):13593-600. Epub 2004 Jan 16.

47.

Prostate-specific membrane antigen association with filamin A modulates its internalization and NAALADase activity.

Anilkumar G, Rajasekaran SA, Wang S, Hankinson O, Bander NH, Rajasekaran AK.

Cancer Res. 2003 May 15;63(10):2645-8.

48.

Mitogen-inducible gene 6 (MIG-6), adipophilin and tuftelin are inducible by hypoxia.

Saarikoski ST, Rivera SP, Hankinson O.

FEBS Lett. 2002 Oct 23;530(1-3):186-90.

49.

Recruitment of the NCoA/SRC-1/p160 family of transcriptional coactivators by the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator complex.

Beischlag TV, Wang S, Rose DW, Torchia J, Reisz-Porszasz S, Muhammad K, Nelson WE, Probst MR, Rosenfeld MG, Hankinson O.

Mol Cell Biol. 2002 Jun;22(12):4319-33.

50.

Identification of a novel dioxin-inducible cytochrome P450.

Rivera SP, Saarikoski ST, Hankinson O.

Mol Pharmacol. 2002 Feb;61(2):255-9.

PMID:
11809848

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