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Items: 10


A Novel Inhibitor of the LolCDE ABC Transporter Essential for Lipoprotein Trafficking in Gram-Negative Bacteria.

Nickerson NN, Jao CC, Xu Y, Quinn J, Skippington E, Alexander MK, Miu A, Skelton N, Hankins JV, Lopez MS, Koth CM, Rutherford S, Nishiyama M.

Antimicrob Agents Chemother. 2018 Mar 27;62(4). pii: e02151-17. doi: 10.1128/AAC.02151-17. Print 2018 Apr.


The outer membrane of Gram-negative bacteria: lipid A isolation and characterization.

Hankins JV, Madsen JA, Needham BD, Brodbelt JS, Trent MS.

Methods Mol Biol. 2013;966:239-258. doi: 10.1007/978-1-62703-245-2_15.


Amino acid addition to Vibrio cholerae LPS establishes a link between surface remodeling in gram-positive and gram-negative bacteria.

Hankins JV, Madsen JA, Giles DK, Brodbelt JS, Trent MS.

Proc Natl Acad Sci U S A. 2012 May 29;109(22):8722-7. doi: 10.1073/pnas.1201313109. Epub 2012 May 15.


Elucidation of a novel Vibrio cholerae lipid A secondary hydroxy-acyltransferase and its role in innate immune recognition.

Hankins JV, Madsen JA, Giles DK, Childers BM, Klose KE, Brodbelt JS, Trent MS.

Mol Microbiol. 2011 Sep;81(5):1313-29. doi: 10.1111/j.1365-2958.2011.07765.x. Epub 2011 Jul 18.


The pmrCAB operon mediates polymyxin resistance in Acinetobacter baumannii ATCC 17978 and clinical isolates through phosphoethanolamine modification of lipid A.

Arroyo LA, Herrera CM, Fernandez L, Hankins JV, Trent MS, Hancock RE.

Antimicrob Agents Chemother. 2011 Aug;55(8):3743-51. doi: 10.1128/AAC.00256-11. Epub 2011 Jun 6.


Remodelling of the Vibrio cholerae membrane by incorporation of exogenous fatty acids from host and aquatic environments.

Giles DK, Hankins JV, Guan Z, Trent MS.

Mol Microbiol. 2011 Feb;79(3):716-28. doi: 10.1111/j.1365-2958.2010.07476.x. Epub 2010 Dec 7.


Activation of PmrA inhibits LpxT-dependent phosphorylation of lipid A promoting resistance to antimicrobial peptides.

Herrera CM, Hankins JV, Trent MS.

Mol Microbiol. 2010 Jun;76(6):1444-60. doi: 10.1111/j.1365-2958.2010.07150.x. Epub 2010 Apr 1.


Secondary acylation of Vibrio cholerae lipopolysaccharide requires phosphorylation of Kdo.

Hankins JV, Trent MS.

J Biol Chem. 2009 Sep 18;284(38):25804-12. doi: 10.1074/jbc.M109.022772. Epub 2009 Jul 17.


Periplasmic phosphorylation of lipid A is linked to the synthesis of undecaprenyl phosphate.

Touzé T, Tran AX, Hankins JV, Mengin-Lecreulx D, Trent MS.

Mol Microbiol. 2008 Jan;67(2):264-77. Epub 2007 Nov 27.


Diversity of endotoxin and its impact on pathogenesis.

Trent MS, Stead CM, Tran AX, Hankins JV.

J Endotoxin Res. 2006;12(4):205-23. Review.


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