Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 131

1.

PI3K: A master regulator of brain metastasis-promoting macrophages/microglia.

Blazquez R, Wlochowitz D, Wolff A, Seitz S, Wachter A, Perera-Bel J, Bleckmann A, Beißbarth T, Salinas G, Riemenschneider MJ, Proescholdt M, Evert M, Utpatel K, Siam L, Schatlo B, Balkenhol M, Stadelmann C, Schildhaus HU, Korf U, Reinz E, Wiemann S, Vollmer E, Schulz M, Ritter U, Hanisch UK, Pukrop T.

Glia. 2018 Nov;66(11):2438-2455. doi: 10.1002/glia.23485. Epub 2018 Oct 25.

PMID:
30357946
2.

Activin A increases phagocytosis of Escherichia coli K1 by primary murine microglial cells activated by toll-like receptor agonists.

Diesselberg C, Ribes S, Seele J, Kaufmann A, Redlich S, Bunkowski S, Hanisch UK, Michel U, Nau R, Schütze S.

J Neuroinflammation. 2018 Jun 7;15(1):175. doi: 10.1186/s12974-018-1209-2.

3.

Treatment with 5-azacitidine delay growth of glioblastoma xenografts: a potential new treatment approach for glioblastomas.

Kratzsch T, Kuhn SA, Joedicke A, Hanisch UK, Vajkoczy P, Hoffmann J, Fichtner I.

J Cancer Res Clin Oncol. 2018 May;144(5):809-819. doi: 10.1007/s00432-018-2600-1. Epub 2018 Feb 9.

PMID:
29427211
4.

Interferon-γ-Driven iNOS: A Molecular Pathway to Terminal Shock in Arenavirus Hemorrhagic Fever.

Remy MM, Sahin M, Flatz L, Regen T, Xu L, Kreutzfeldt M, Fallet B, Doras C, Rieger T, Bestmann L, Hanisch UK, Kaufmann BA, Merkler D, Pinschewer DD.

Cell Host Microbe. 2017 Sep 13;22(3):354-365.e5. doi: 10.1016/j.chom.2017.07.008. Epub 2017 Aug 17.

5.

A presumed antagonistic LPS identifies distinct functional organization of TLR4 in mouse microglia.

Döring C, Regen T, Gertig U, van Rossum D, Winkler A, Saiepour N, Brück W, Hanisch UK, Janova H.

Glia. 2017 Jul;65(7):1176-1185. doi: 10.1002/glia.23151. Epub 2017 May 4.

PMID:
28471051
6.

Evaluation of bone remodeling in regard to the age of scaphoid non-unions.

Rein S, Hanisch U, Schaller HE, Zwipp H, Rammelt S, Weindel S.

World J Orthop. 2016 Jul 18;7(7):418-25. doi: 10.5312/wjo.v7.i7.418. eCollection 2016 Jul 18.

7.

Thioredoxins and Methionine Sulfoxide Reductases in the Pathophysiology of Pneumococcal Meningitis.

Ribes S, Abdullah MR, Saleh M, Hanisch UK, Nau R, Hammerschmidt S.

J Infect Dis. 2016 Sep 15;214(6):953-61. doi: 10.1093/infdis/jiw268. Epub 2016 Jul 1.

PMID:
27368348
8.

Laquinimod prevents cuprizone-induced demyelination independent of Toll-like receptor signaling.

Kramann N, Menken L, Hayardeny L, Hanisch UK, Brück W.

Neurol Neuroimmunol Neuroinflamm. 2016 May 17;3(3):e233. doi: 10.1212/NXI.0000000000000233. eCollection 2016 Jun.

9.

TLR4-activated microglia require IFN-γ to induce severe neuronal dysfunction and death in situ.

Papageorgiou IE, Lewen A, Galow LV, Cesetti T, Scheffel J, Regen T, Hanisch UK, Kann O.

Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):212-7. doi: 10.1073/pnas.1513853113. Epub 2015 Dec 22.

10.

CD14 is a key organizer of microglial responses to CNS infection and injury.

Janova H, Böttcher C, Holtman IR, Regen T, van Rossum D, Götz A, Ernst AS, Fritsche C, Gertig U, Saiepour N, Gronke K, Wrzos C, Ribes S, Rolfes S, Weinstein J, Ehrenreich H, Pukrop T, Kopatz J, Stadelmann C, Salinas-Riester G, Weber MS, Prinz M, Brück W, Eggen BJ, Boddeke HW, Priller J, Hanisch UK.

Glia. 2016 Apr;64(4):635-49. doi: 10.1002/glia.22955. Epub 2015 Dec 18.

PMID:
26683584
11.

Cell type- and brain region-resolved mouse brain proteome.

Sharma K, Schmitt S, Bergner CG, Tyanova S, Kannaiyan N, Manrique-Hoyos N, Kongi K, Cantuti L, Hanisch UK, Philips MA, Rossner MJ, Mann M, Simons M.

Nat Neurosci. 2015 Dec;18(12):1819-31. doi: 10.1038/nn.4160. Epub 2015 Nov 2.

PMID:
26523646
12.

Ex Vivo Intra-arterial Methylene Blue Injection in Rectal Cancer Specimens Increases the Lymph-Node Harvest, Especially After Preoperative Radiation.

Münster M, Hanisch U, Tuffaha M, Kube R, Ptok H.

World J Surg. 2016 Feb;40(2):463-70. doi: 10.1007/s00268-015-3230-2.

PMID:
26310202
13.

Anti-CSF-1 treatment is effective to prevent carcinoma invasion induced by monocyte-derived cells but scarcely by microglia.

Rietkötter E, Bleckmann A, Bayerlová M, Menck K, Chuang HN, Wenske B, Schwartz H, Erez N, Binder C, Hanisch UK, Pukrop T.

Oncotarget. 2015 Jun 20;6(17):15482-93.

14.

Erythropoietin dampens injury-induced microglial motility.

Mitkovski M, Dahm L, Heinrich R, Monnheimer M, Gerhart S, Stegmüller J, Hanisch UK, Nave KA, Ehrenreich H.

J Cereb Blood Flow Metab. 2015 Aug;35(8):1233-6. doi: 10.1038/jcbfm.2015.100. Epub 2015 May 13.

15.

Long-lasting pro-inflammatory suppression of microglia by LPS-preconditioning is mediated by RelB-dependent epigenetic silencing.

Schaafsma W, Zhang X, van Zomeren KC, Jacobs S, Georgieva PB, Wolf SA, Kettenmann H, Janova H, Saiepour N, Hanisch UK, Meerlo P, van den Elsen PJ, Brouwer N, Boddeke HW, Eggen BJ.

Brain Behav Immun. 2015 Aug;48:205-21. doi: 10.1016/j.bbi.2015.03.013. Epub 2015 Apr 2.

PMID:
25843371
16.

Tyrphostin AG126 exerts neuroprotection in CNS inflammation by a dual mechanism.

Menzfeld C, John M, van Rossum D, Regen T, Scheffel J, Janova H, Götz A, Ribes S, Nau R, Borisch A, Boutin P, Neumann K, Bremes V, Wienands J, Reichardt HM, Lühder F, Tischner D, Waetzig V, Herdegen T, Teismann P, Greig I, Müller M, Pukrop T, Mildner A, Kettenmann H, Brück W, Prinz M, Rotshenker S, Weber MS, Hanisch UK.

Glia. 2015 Jun;63(6):1083-99. doi: 10.1002/glia.22803. Epub 2015 Mar 2.

PMID:
25731696
17.

Vitamin D deficiency decreases survival of bacterial meningoencephalitis in mice.

Djukic M, Sostmann N, Bertsch T, Mecke M, Nessler S, Manig A, Hanisch UK, Triebel J, Bollheimer LC, Sieber C, Nau R.

J Neuroinflammation. 2015 Jan 7;12:208. doi: 10.1186/s12974-014-0208-1.

18.

Higher mortality and impaired elimination of bacteria in aged mice after intracerebral infection with E. coli are associated with an age-related decline of microglia and macrophage functions.

Schütze S, Ribes S, Kaufmann A, Manig A, Scheffel J, Redlich S, Bunkowski S, Hanisch UK, Brück W, Nau R.

Oncotarget. 2014 Dec 30;5(24):12573-92.

19.

CD11c-positive cells from brain, spleen, lung, and liver exhibit site-specific immune phenotypes and plastically adapt to new environments.

Immig K, Gericke M, Menzel F, Merz F, Krueger M, Schiefenhövel F, Lösche A, Jäger K, Hanisch UK, Biber K, Bechmann I.

Glia. 2015 Apr;63(4):611-25. doi: 10.1002/glia.22771. Epub 2014 Dec 3.

PMID:
25471735
20.

Influence of intrathecal delivery of bone marrow-derived mesenchymal stem cells on spinal inflammation and pain hypersensitivity in a rat model of peripheral nerve injury.

Schäfer S, Berger JV, Deumens R, Goursaud S, Hanisch UK, Hermans E.

J Neuroinflammation. 2014 Sep 12;11:157. doi: 10.1186/s12974-014-0157-8.

21.

Microglial diversity by responses and responders.

Gertig U, Hanisch UK.

Front Cell Neurosci. 2014 Apr 1;8:101. doi: 10.3389/fncel.2014.00101. eCollection 2014. Review.

22.

Vitamin d deficiency reduces the immune response, phagocytosis rate, and intracellular killing rate of microglial cells.

Djukic M, Onken ML, Schütze S, Redlich S, Götz A, Hanisch UK, Bertsch T, Ribes S, Hanenberg A, Schneider S, Bollheimer C, Sieber C, Nau R.

Infect Immun. 2014 Jun;82(6):2585-94. doi: 10.1128/IAI.01814-14. Epub 2014 Mar 31.

23.

Overexpression of protease-activated receptor type 1 (PAR-1) in glioblastoma multiforme WHO IV cells and blood vessels revealed by NCAM-assisted glioblastoma border labeling.

Kuhn SA, Martin M, Brodhun M, Kratzsch T, Hanisch UK, Haberl H.

Neurol Res. 2014 Aug;36(8):709-21. doi: 10.1179/1743132813Y.0000000303. Epub 2014 Jan 29.

PMID:
24620969
24.

Linking STAT and TLR signaling in microglia: a new role for the histone demethylase Jmjd3.

Hanisch UK.

J Mol Med (Berl). 2014 Mar;92(3):197-200. doi: 10.1007/s00109-014-1122-9. No abstract available.

PMID:
24500110
25.

Intraperitoneal prophylaxis with CpG oligodeoxynucleotides protects neutropenic mice against intracerebral Escherichia coli K1 infection.

Ribes S, Meister T, Ott M, Redlich S, Janova H, Hanisch UK, Nessler S, Nau R.

J Neuroinflammation. 2014 Jan 23;11:14. doi: 10.1186/1742-2094-11-14.

26.

Rho kinase inhibition modulates microglia activation and improves survival in a model of amyotrophic lateral sclerosis.

Tönges L, Günther R, Suhr M, Jansen J, Balck A, Saal KA, Barski E, Nientied T, Götz AA, Koch JC, Mueller BK, Weishaupt JH, Sereda MW, Hanisch UK, Bähr M, Lingor P.

Glia. 2014 Feb;62(2):217-32. doi: 10.1002/glia.22601. Epub 2013 Dec 6.

PMID:
24311453
27.

Coculture system with an organotypic brain slice and 3D spheroid of carcinoma cells.

Chuang HN, Lohaus R, Hanisch UK, Binder C, Dehghani F, Pukrop T.

J Vis Exp. 2013 Oct 9;(80). doi: 10.3791/50881.

28.

Zoledronic acid inhibits macrophage/microglia-assisted breast cancer cell invasion.

Rietkötter E, Menck K, Bleckmann A, Farhat K, Schaffrinski M, Schulz M, Hanisch UK, Binder C, Pukrop T.

Oncotarget. 2013 Sep;4(9):1449-60.

29.

Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion.

Vinnakota K, Hu F, Ku MC, Georgieva PB, Szulzewsky F, Pohlmann A, Waiczies S, Waiczies H, Niendorf T, Lehnardt S, Hanisch UK, Synowitz M, Markovic D, Wolf SA, Glass R, Kettenmann H.

Neuro Oncol. 2013 Nov;15(11):1457-68. doi: 10.1093/neuonc/not115. Epub 2013 Sep 5.

30.

Empty liposomes induce antitumoral effects associated with macrophage responses distinct from those of the TLR1/2 agonist Pam3CSK 4 (BLP).

König S, Regen T, Dittmann K, Engelke M, Wienands J, Schwendener R, Hanisch UK, Pukrop T, Hahn H.

Cancer Immunol Immunother. 2013 Oct;62(10):1587-97. doi: 10.1007/s00262-013-1444-4. Epub 2013 Aug 6.

31.

Microglial phenotype and adaptation.

Eggen BJ, Raj D, Hanisch UK, Boddeke HW.

J Neuroimmune Pharmacol. 2013 Sep;8(4):807-23. doi: 10.1007/s11481-013-9490-4. Epub 2013 Jul 25. Review.

PMID:
23881706
32.

Carcinoma cells misuse the host tissue damage response to invade the brain.

Chuang HN, van Rossum D, Sieger D, Siam L, Klemm F, Bleckmann A, Bayerlová M, Farhat K, Scheffel J, Schulz M, Dehghani F, Stadelmann C, Hanisch UK, Binder C, Pukrop T.

Glia. 2013 Aug;61(8):1331-46. doi: 10.1002/glia.22518. Epub 2013 Jul 6.

33.

Functional diversity of microglia - how heterogeneous are they to begin with?

Hanisch UK.

Front Cell Neurosci. 2013 May 14;7:65. doi: 10.3389/fncel.2013.00065. eCollection 2013.

34.

Histone deacetylase inhibitors suppress immune activation in primary mouse microglia.

Kannan V, Brouwer N, Hanisch UK, Regen T, Eggen BJ, Boddeke HW.

J Neurosci Res. 2013 Sep;91(9):1133-42. doi: 10.1002/jnr.23221. Epub 2013 May 17.

PMID:
23686642
35.

Resistance of the brain to Escherichia coli K1 infection depends on MyD88 signaling and the contribution of neutrophils and monocytes.

Ribes S, Regen T, Meister T, Tauber SC, Schütze S, Mildner A, Mack M, Hanisch UK, Nau R.

Infect Immun. 2013 May;81(5):1810-9. doi: 10.1128/IAI.01349-12. Epub 2013 Mar 11.

36.

Comparative analysis of inter- and intraligamentous distribution of sensory nerve endings in ankle ligaments: a cadaver study.

Rein S, Hanisch U, Zwipp H, Fieguth A, Lwowski S, Hagert E.

Foot Ankle Int. 2013 Jul;34(7):1017-24. doi: 10.1177/1071100713480862. Epub 2013 Mar 1.

PMID:
23456084
37.

Proteins in microglial activation--inputs and outputs by subsets.

Hanisch UK.

Curr Protein Pept Sci. 2013 Feb;14(1):3-15. Review.

PMID:
23441901
38.

Immunohistochemical analysis of sensory nerve endings in ankle ligaments: a cadaver study.

Rein S, Hagert E, Hanisch U, Lwowski S, Fieguth A, Zwipp H.

Cells Tissues Organs. 2013;197(1):64-76. doi: 10.1159/000339877. Epub 2012 Sep 4.

39.

Influence of methylene blue on microglia-induced inflammation and motor neuron degeneration in the SOD1(G93A) model for ALS.

Dibaj P, Zschüntzsch J, Steffens H, Scheffel J, Göricke B, Weishaupt JH, Le Meur K, Kirchhoff F, Hanisch UK, Schomburg ED, Neusch C.

PLoS One. 2012;7(8):e43963. doi: 10.1371/journal.pone.0043963. Epub 2012 Aug 27.

40.

Toll-like receptor activation reveals developmental reorganization and unmasks responder subsets of microglia.

Scheffel J, Regen T, Van Rossum D, Seifert S, Ribes S, Nau R, Parsa R, Harris RA, Boddeke HW, Chuang HN, Pukrop T, Wessels JT, Jürgens T, Merkler D, Brück W, Schnaars M, Simons M, Kettenmann H, Hanisch UK.

Glia. 2012 Dec;60(12):1930-43. doi: 10.1002/glia.22409. Epub 2012 Aug 21.

PMID:
22911652
41.

The nucleotide-binding oligomerization domain-containing-2 ligand muramyl dipeptide enhances phagocytosis and intracellular killing of Escherichia coli K1 by Toll-like receptor agonists in microglial cells.

Ribes S, Adam N, Schütze S, Regen T, Redlich S, Janova H, Borisch A, Hanisch UK, Nau R.

J Neuroimmunol. 2012 Nov 15;252(1-2):16-23. doi: 10.1016/j.jneuroim.2012.07.012. Epub 2012 Aug 11.

PMID:
22889567
42.

Complement receptor-3 negatively regulates the phagocytosis of degenerated myelin through tyrosine kinase Syk and cofilin.

Hadas S, Spira M, Hanisch UK, Reichert F, Rotshenker S.

J Neuroinflammation. 2012 Jul 9;9:166. doi: 10.1186/1742-2094-9-166.

43.

Reduced astrocytic NF-κB activation by laquinimod protects from cuprizone-induced demyelination.

Brück W, Pförtner R, Pham T, Zhang J, Hayardeny L, Piryatinsky V, Hanisch UK, Regen T, van Rossum D, Brakelmann L, Hagemeier K, Kuhlmann T, Stadelmann C, John GR, Kramann N, Wegner C.

Acta Neuropathol. 2012 Sep;124(3):411-24. doi: 10.1007/s00401-012-1009-1. Epub 2012 Jul 6.

44.

Do pharmacokinetics explain persistent restenosis inhibition by a single dose of paclitaxel?

Speck U, Cremers B, Kelsch B, Biedermann M, Clever YP, Schaffner S, Mahnkopf D, Hanisch U, Böhm M, Scheller B.

Circ Cardiovasc Interv. 2012 Jun;5(3):392-400. doi: 10.1161/CIRCINTERVENTIONS.111.967794. Epub 2012 May 22.

PMID:
22619258
45.

Straightforward thiol-mediated protein labelling with DTPA: Synthesis of a highly active 111In-annexin A5-DTPA tracer.

Kratz H, Haeckel A, Michel R, Schönzart L, Hanisch U, Hamm B, Schellenberger E.

EJNMMI Res. 2012 Apr 27;2(1):17. doi: 10.1186/2191-219X-2-17.

46.

Expression of coagulation factors and their receptors in tumor tissue and coagulation factor upregulation in peripheral blood of patients with cerebral carcinoma metastases.

Walter J, Handel LL, Brodhun M, van Rossum D, Hanisch UK, Liebmann L, Heppner F, Goldbrunner R, Koch A, Kuhn SA.

J Cancer Res Clin Oncol. 2012 Jan;138(1):141-51. doi: 10.1007/s00432-011-1078-x. Epub 2011 Nov 8.

PMID:
22065054
47.

Physiology of microglia.

Kettenmann H, Hanisch UK, Noda M, Verkhratsky A.

Physiol Rev. 2011 Apr;91(2):461-553. doi: 10.1152/physrev.00011.2010. Review.

48.

Neonatal freshwater drowning after birth in the bathroom.

Dressler J, Schmidt U, Hanisch U, Demmler G, Riehn A, Pollak S.

Am J Forensic Med Pathol. 2011 Jun;32(2):119-23. doi: 10.1097/PAF.0b013e318187dff9.

PMID:
21297437
49.

Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis.

Fitzner D, Schnaars M, van Rossum D, Krishnamoorthy G, Dibaj P, Bakhti M, Regen T, Hanisch UK, Simons M.

J Cell Sci. 2011 Feb 1;124(Pt 3):447-58. doi: 10.1242/jcs.074088.

50.

CD14 and TRIF govern distinct responsiveness and responses in mouse microglial TLR4 challenges by structural variants of LPS.

Regen T, van Rossum D, Scheffel J, Kastriti ME, Revelo NH, Prinz M, Brück W, Hanisch UK.

Brain Behav Immun. 2011 Jul;25(5):957-70. doi: 10.1016/j.bbi.2010.10.009. Epub 2010 Oct 15.

PMID:
20951794

Supplemental Content

Loading ...
Support Center