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Items: 1 to 50 of 127

1.

Wogonin glucuronidation in liver and intestinal microsomes of humans, monkeys, dogs, rats, and mice.

Hanioka N, Isobe T, Tanaka-Kagawa T, Ohkawara S.

Xenobiotica. 2020 Feb 12:1-7. doi: 10.1080/00498254.2020.1725180. [Epub ahead of print]

PMID:
32005083
2.

S-equol glucuronidation in liver and intestinal microsomes of humans, monkeys, dogs, rats, and mice.

Isobe T, Ohkawara S, Ochi S, Tanaka-Kagawa T, Hanioka N.

Food Chem Toxicol. 2019 Sep;131:110542. doi: 10.1016/j.fct.2019.05.050. Epub 2019 Jun 1.

PMID:
31163218
3.

Hydrolysis of di(2-ethylhexyl) phthalate in humans, monkeys, dogs, rats, and mice: An in vitro analysis using liver and intestinal microsomes.

Hanioka N, Isobe T, Ohkawara S, Ochi S, Tanaka-Kagawa T, Jinno H.

Toxicol In Vitro. 2019 Feb;54:237-242. doi: 10.1016/j.tiv.2018.10.006. Epub 2018 Oct 10.

PMID:
30315871
4.

Evaluation of Tumor Tissue Fixation Effects of Formulation Modified Mohs Pastes in Mice and Their Water-Absorbing Properties.

Taguchi M, Shigeyama M, Ogawa N, Murata M, Hanioka N, Yamamoto H, Teramachi H.

Biol Pharm Bull. 2018 Dec 1;41(12):1824-1829. doi: 10.1248/bpb.b18-00528. Epub 2018 Oct 2.

5.

Regioselective glucuronidation of daidzein in liver and intestinal microsomes of humans, monkeys, rats, and mice.

Hanioka N, Ohkawara S, Isobe T, Ochi S, Tanaka-Kagawa T, Jinno H.

Arch Toxicol. 2018 Sep;92(9):2809-2817. doi: 10.1007/s00204-018-2265-1. Epub 2018 Jul 16.

PMID:
30014295
6.

Carbamazepine 10,11-epoxidation in human liver microsomes: influence of the CYP3A5*3 polymorphism.

Miyata-Nozaka Y, Zain SM, Taguchi M, Shigeyama M, Isobe T, Hanioka N.

Pharmazie. 2017 Dec 1;72(12):747-750. doi: 10.1691/ph.2017.7754.

PMID:
29441960
7.

Naringenin glucuronidation in liver and intestine microsomes of humans, monkeys, rats, and mice.

Isobe T, Ohkawara S, Ochi S, Tanaka-Kagawa T, Jinno H, Hanioka N.

Food Chem Toxicol. 2018 Jan;111:417-422. doi: 10.1016/j.fct.2017.11.057. Epub 2017 Dec 1.

PMID:
29198856
8.

Hepatic glucuronidation of 4-tert-octylphenol in humans: inter-individual variability and responsible UDP-glucuronosyltransferase isoforms.

Isobe T, Ohkawara S, Tanaka-Kagawa T, Jinno H, Hanioka N.

Arch Toxicol. 2017 Nov;91(11):3543-3550. doi: 10.1007/s00204-017-1982-1. Epub 2017 May 12.

PMID:
28500425
9.

Preparation and Evaluation of Modified Mohs Paste without Starch.

Taguchi M, Shigeyama M, Ito N, Ogawa N, Takahashi C, Murata M, Hanioka N, Yamamoto H, Teramachi H.

Yakugaku Zasshi. 2017;137(4):477-484. doi: 10.1248/yakushi.16-00248. Japanese.

10.

Glucuronidation of 4-tert-octylphenol in humans, monkeys, rats, and mice: an in vitro analysis using liver and intestine microsomes.

Hanioka N, Isobe T, Ohkawara S, Tanaka-Kagawa T, Jinno H.

Arch Toxicol. 2017 Mar;91(3):1227-1232. doi: 10.1007/s00204-016-1800-1. Epub 2016 Jul 12.

PMID:
27405656
11.

Glucuronidation of mono(2-ethylhexyl) phthalate in humans: roles of hepatic and intestinal UDP-glucuronosyltransferases.

Hanioka N, Kinashi Y, Tanaka-Kagawa T, Isobe T, Jinno H.

Arch Toxicol. 2017 Feb;91(2):689-698. doi: 10.1007/s00204-016-1708-9. Epub 2016 Apr 12.

PMID:
27071666
12.

Adsorption of histones on natural polysaccharides: The potential as agent for multiple organ failure in sepsis.

Isobe T, Kofuji K, Okada K, Fujimori J, Murata M, Shigeyama M, Hanioka N, Murata Y.

Int J Biol Macromol. 2016 Mar;84:54-7. doi: 10.1016/j.ijbiomac.2015.11.029. Epub 2015 Nov 25.

PMID:
26627603
13.

Hepatic and intestinal glucuronidation of mono(2-ethylhexyl) phthalate, an active metabolite of di(2-ethylhexyl) phthalate, in humans, dogs, rats, and mice: an in vitro analysis using microsomal fractions.

Hanioka N, Isobe T, Kinashi Y, Tanaka-Kagawa T, Jinno H.

Arch Toxicol. 2016 Jul;90(7):1651-7. doi: 10.1007/s00204-015-1619-1. Epub 2015 Oct 29.

PMID:
26514348
14.

Species and sex differences in propofol glucuronidation in liver microsomes of humans, monkeys, rats and mice.

Mukai M, Isobe T, Okada K, Murata M, Shigeyama M, Hanioka N.

Pharmazie. 2015 Jul;70(7):466-70.

PMID:
26373207
15.

Raloxifene glucuronidation in liver and intestinal microsomes of humans and monkeys: contribution of UGT1A1, UGT1A8 and UGT1A9.

Kishi N, Takasuka A, Kokawa Y, Isobe T, Taguchi M, Shigeyama M, Murata M, Suno M, Hanioka N.

Xenobiotica. 2016;46(4):289-95. doi: 10.3109/00498254.2015.1074301. Epub 2015 Aug 6.

PMID:
26247833
16.

Molecular cloning and functional analysis of minipig UDP-glucuronosyltransferase 1A6.

Miyake Y, Hirose R, Isobe T, Hanioka N.

Xenobiotica. 2016;46(3):193-9. doi: 10.3109/00498254.2015.1060373. Epub 2015 Jul 1.

PMID:
26134041
17.

In vitro glucuronidation of propofol in microsomal fractions from human liver, intestine and kidney: tissue distribution and physiological role of UGT1A9.

Mukai M, Tanaka S, Yamamoto K, Murata M, Okada K, Isobe T, Shigeyama M, Hichiya H, Hanioka N.

Pharmazie. 2014 Nov;69(11):829-32.

PMID:
25985579
18.

Butylbenzyl phthalate hydrolysis in liver microsomes of humans, monkeys, dogs, rats and mice.

Takahara Y, Kinashi Y, Takahara Y, Hichiya H, Okada K, Murata M, Shigeyama M, Hanioka N.

Biol Pharm Bull. 2014;37(4):703-6.

19.

Functional characterization of cynomolgus monkey UDP-glucuronosyltransferase 1A9.

Yamamoto K, Mukai M, Nagaoka K, Hayashi K, Hichiya H, Okada K, Murata M, Shigeyama M, Narimatsu S, Hanioka N.

Eur J Drug Metab Pharmacokinet. 2014 Sep;39(3):195-202. doi: 10.1007/s13318-014-0177-x. Epub 2014 Jan 28.

PMID:
24470170
20.

Effect of UDP-glucuronosyltransferase 1A8 polymorphism on raloxifene glucuronidation.

Kokawa Y, Kishi N, Jinno H, Tanaka-Kagawa T, Narimatsu S, Hanioka N.

Eur J Pharm Sci. 2013 May 13;49(2):199-205. doi: 10.1016/j.ejps.2013.03.001. Epub 2013 Mar 14.

PMID:
23499758
21.

cDNA cloning and functional analysis of minipig uridine diphosphate-glucuronosyltransferase 1A1.

Miyake Y, Mayumi K, Jinno H, Tanaka-Kagawa T, Narimatsu S, Hanioka N.

Biol Pharm Bull. 2013;36(3):452-61.

22.

Characterization of marmoset CYP2B6: cDNA cloning, protein expression and enzymatic functions.

Mayumi K, Hanioka N, Masuda K, Koeda A, Naito S, Miyata A, Narimatsu S.

Biochem Pharmacol. 2013 Apr 15;85(8):1182-94. doi: 10.1016/j.bcp.2013.01.024. Epub 2013 Feb 5.

PMID:
23395694
23.

Evaluation of animal models for intestinal first-pass metabolism of drug candidates to be metabolized by CYP3A enzymes via in vivo and in vitro oxidation of midazolam and triazolam.

Kuze J, Mutoh T, Takenaka T, Oda N, Hanioka N, Narimatsu S.

Xenobiotica. 2013 Jul;43(7):598-606. doi: 10.3109/00498254.2012.751517. Epub 2013 Jan 3.

PMID:
23282066
24.

Stereoselective glucuronidation of carvedilol in human liver and intestinal microsomes.

Hanioka N, Tanaka S, Moriguchi Y, Narimatsu S.

Pharmacology. 2012;90(3-4):117-24. doi: 10.1159/000340020. Epub 2012 Jul 18.

PMID:
22814440
25.

Effect of aflatoxin B1 on UDP-glucuronosyltransferase mRNA expression in HepG2 cells.

Hanioka N, Nonaka Y, Saito K, Negishi T, Okamoto K, Kataoka H, Narimatsu S.

Chemosphere. 2012 Oct;89(5):526-9. doi: 10.1016/j.chemosphere.2012.05.039. Epub 2012 Jun 29.

PMID:
22749127
26.

Hydrolysis of di-n-butyl phthalate, butylbenzyl phthalate and di(2-ethylhexyl) phthalate in human liver microsomes.

Hanioka N, Takahara Y, Takahara Y, Tanaka-Kagawa T, Jinno H, Narimatsu S.

Chemosphere. 2012 Nov;89(9):1112-7. doi: 10.1016/j.chemosphere.2012.05.095. Epub 2012 Jun 25.

PMID:
22739543
27.

The effects of N-glycosylation on the glucuronidation of zidovudine and morphine by UGT2B7 expressed in HEK293 cells.

Nagaoka K, Hanioka N, Ikushiro S, Yamano S, Narimatsu S.

Drug Metab Pharmacokinet. 2012;27(4):388-97. Epub 2012 Jan 13.

28.

Characterization of inhibitory effects of perfluorooctane sulfonate on human hepatic cytochrome P450 isoenzymes: focusing on CYP2A6.

Narimatsu S, Nakanishi R, Hanioka N, Saito K, Kataoka H.

Chem Biol Interact. 2011 Nov 15;194(2-3):120-6. doi: 10.1016/j.cbi.2011.09.002. Epub 2011 Sep 19.

PMID:
21964418
29.

Expression and inducibility of UDP-glucuronosyltransferase 1As in MCF-7 human breast carcinoma cells.

Hanioka N, Iwabu H, Hanafusa H, Nakada S, Narimatsu S.

Basic Clin Pharmacol Toxicol. 2012 Mar;110(3):253-8. doi: 10.1111/j.1742-7843.2011.00790.x. Epub 2011 Oct 10.

30.

Effect of UDP-glucuronosyltransferase 2B15 polymorphism on bisphenol A glucuronidation.

Hanioka N, Oka H, Nagaoka K, Ikushiro S, Narimatsu S.

Arch Toxicol. 2011 Nov;85(11):1373-81. doi: 10.1007/s00204-011-0690-5. Epub 2011 Mar 15.

PMID:
21404072
31.

Influence of CYP2C8*13 and CYP2C8*14 alleles on amiodarone N-deethylation.

Hanioka N, Matsumoto K, Saito Y, Narimatsu S.

Basic Clin Pharmacol Toxicol. 2011 May;108(5):359-62. doi: 10.1111/j.1742-7843.2010.00669.x. Epub 2011 Jan 31. No abstract available.

32.

Regio- and stereoselective oxidation of propranolol enantiomers by human CYP2D6, cynomolgus monkey CYP2D17 and marmoset CYP2D19.

Narimatsu S, Nakata T, Shimizudani T, Nagaoka K, Nakura H, Masuda K, Katsu T, Koeda A, Naito S, Yamano S, Miyata A, Hanioka N.

Chem Biol Interact. 2011 Feb 1;189(3):146-52. doi: 10.1016/j.cbi.2010.12.014. Epub 2010 Dec 22.

PMID:
21184751
33.

Determination of polycyclic aromatic hydrocarbons in food samples by automated on-line in-tube solid-phase microextraction coupled with high-performance liquid chromatography-fluorescence detection.

Ishizaki A, Saito K, Hanioka N, Narimatsu S, Kataoka H.

J Chromatogr A. 2010 Aug 27;1217(35):5555-63. doi: 10.1016/j.chroma.2010.06.068. Epub 2010 Jun 30.

PMID:
20637468
34.

Functional characterization of human and cynomolgus monkey UDP-glucuronosyltransferase 1A1 enzymes.

Hanioka N, Tanabe N, Jinno H, Tanaka-Kagawa T, Nagaoka K, Naito S, Koeda A, Narimatsu S.

Life Sci. 2010 Aug 14;87(7-8):261-8. doi: 10.1016/j.lfs.2010.07.001. Epub 2010 Jul 8.

PMID:
20620155
35.

Functional characterization of CYP2C8.13 and CYP2C8.14: catalytic activities toward paclitaxel.

Hanioka N, Matsumoto K, Saito Y, Narimatsu S.

Basic Clin Pharmacol Toxicol. 2010 Jul;107(1):565-9. doi: 10.1111/j.1742-7843.2010.00543.x. Epub 2010 Feb 10.

36.

Functional characterization of human cytochrome P4502E1 allelic variants: in vitro metabolism of benzene and toluene by recombinant enzymes expressed in yeast cells.

Hanioka N, Yamamoto M, Tanaka-Kagawa T, Jinno H, Narimatsu S.

Arch Toxicol. 2010 May;84(5):363-71. doi: 10.1007/s00204-009-0504-1. Epub 2009 Dec 24.

PMID:
20033806
37.

Comparative study of the oxidation of propranolol enantiomers in hepatic and small intestinal microsomes from cynomolgus and marmoset monkeys.

Shimizudani T, Nagaoka K, Hanioka N, Yamano S, Narimatsu S.

Chem Biol Interact. 2010 Jan 5;183(1):67-78. doi: 10.1016/j.cbi.2009.10.007.

PMID:
19853591
38.

Separate evaluation of intestinal and hepatic metabolism of three benzodiazepines in rats with cannulated portal and jugular veins: comparison with the profile in non-cannulated mice.

Kuze J, Mutoh T, Takenaka T, Morisaki K, Nakura H, Hanioka N, Narimatsu S.

Xenobiotica. 2009 Nov;39(11):871-80. doi: 10.3109/00498250903215382.

PMID:
19845438
39.

Determination of aflatoxins in food samples by automated on-line in-tube solid-phase microextraction coupled with liquid chromatography-mass spectrometry.

Nonaka Y, Saito K, Hanioka N, Narimatsu S, Kataoka H.

J Chromatogr A. 2009 May 15;1216(20):4416-22. doi: 10.1016/j.chroma.2009.03.035. Epub 2009 Mar 18.

PMID:
19328492
40.

Functional characterization of CYP3A4.16: catalytic activities toward midazolam and carbamazepine.

Maekawa K, Yoshimura T, Saito Y, Fujimura Y, Aohara F, Emoto C, Iwasaki K, Hanioka N, Narimatsu S, Niwa T, Sawada J.

Xenobiotica. 2009 Feb;39(2):140-7. doi: 10.1080/00498250802617746.

PMID:
19255940
41.

The mechanism causing the difference in kinetic properties between rat CYP2D4 and human CYP2D6 in the oxidation of dextromethorphan and bufuralol.

Narimatsu S, Kazamori D, Masuda K, Katsu T, Funae Y, Naito S, Nakura H, Yamano S, Hanioka N.

Biochem Pharmacol. 2009 Mar 1;77(5):920-31. doi: 10.1016/j.bcp.2008.11.006. Epub 2008 Nov 17.

PMID:
19059219
42.

Human UDP-glucuronosyltransferase isoforms involved in bisphenol A glucuronidation.

Hanioka N, Naito T, Narimatsu S.

Chemosphere. 2008 Dec;74(1):33-6. doi: 10.1016/j.chemosphere.2008.09.053. Epub 2008 Nov 5.

PMID:
18990428
43.

Stereoselective glucuronidation of propranolol in human and cynomolgus monkey liver microsomes: role of human hepatic UDP-glucuronosyltransferase isoforms, UGT1A9, UGT2B4 and UGT2B7.

Hanioka N, Hayashi K, Shimizudani T, Nagaoka K, Koeda A, Naito S, Narimatsu S.

Pharmacology. 2008;82(4):293-303. doi: 10.1159/000165100. Epub 2008 Oct 21.

PMID:
18936551
44.

A caffeine-sensitive membrane electrode: previous misleading report and present approach.

Katsu T, Tsunamoto Y, Hanioka N, Komagoe K, Masuda K, Narimatsu S.

Anal Chim Acta. 2008 Jul 14;620(1-2):50-4. doi: 10.1016/j.aca.2008.05.027. Epub 2008 May 21.

45.

Influence of CYP2C19*18 and CYP2C19*19 alleles on omeprazole 5-hydroxylation: in vitro functional analysis of recombinant enzymes expressed in Saccharomyces cerevisiae.

Hanioka N, Tsuneto Y, Saito Y, Maekawa K, Sawada J, Narimatsu S.

Basic Clin Pharmacol Toxicol. 2008 Apr;102(4):388-93. doi: 10.1111/j.1742-7843.2008.00222.x. Epub 2008 Feb 29.

46.

Interaction of bisphenol A with human UDP-glucuronosyltransferase 1A6 enzyme.

Hanioka N, Takeda Y, Tanaka-Kagawa T, Hayashi K, Jinno H, Narimatsu S.

Environ Toxicol. 2008 Jun;23(3):407-12. doi: 10.1002/tox.20345.

PMID:
18214896
47.

The roles of amino acid residues at positions 216 and 219 in the structural stability and metabolic functions of rat cytochrome P450 2D1 and 2D2.

Narimatsu S, Kiryu K, Yonemoto R, Yoshino M, Kobatake M, Kazamori D, Hagino S, Masuda K, Katsu T, Asanuma M, Kumamoto T, Ishikawa T, Funae Y, Yamano S, Hanioka N, Naito S.

Chem Biol Interact. 2008 Mar 10;172(1):11-21. doi: 10.1016/j.cbi.2007.11.010. Epub 2007 Nov 28.

PMID:
18191824
48.

Oxidation of 5-methoxy-N,N-diisopropyltryptamine in rat liver microsomes and recombinant cytochrome P450 enzymes.

Narimatsu S, Yonemoto R, Masuda K, Katsu T, Asanuma M, Kamata T, Katagi M, Tsuchihashi H, Kumamoto T, Ishikawa T, Naito S, Yamano S, Hanioka N.

Biochem Pharmacol. 2008 Feb 1;75(3):752-60. Epub 2007 Sep 29.

PMID:
17980859
49.

Functional characterization of human and cynomolgus monkey cytochrome P450 2E1 enzymes.

Hanioka N, Yamamoto M, Iwabu H, Jinno H, Tanaka-Kagawa T, Naito S, Shimizu T, Masuda K, Katsu T, Narimatsu S.

Life Sci. 2007 Oct 27;81(19-20):1436-45. Epub 2007 Sep 15.

PMID:
17935737
50.

Stereoselective hexobarbital 3'-hydroxylation by CYP2C19 expressed in yeast cells and the roles of amino acid residues at positions 300 and 476.

Saito K, Dan H, Masuda K, Katsu T, Hanioka N, Yamamoto S, Miyano K, Yamano S, Narimatsu S.

Chirality. 2007 Jul;19(7):550-8.

PMID:
17487889

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