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Items: 1 to 50 of 63

1.

Structure of 6-diazo-5-oxo-norleucine-bound human gamma-glutamyl transpeptidase 1, a novel mechanism of inactivation.

Terzyan SS, Cook PF, Heroux A, Hanigan MH.

Protein Sci. 2017 Jun;26(6):1196-1205. doi: 10.1002/pro.3172. Epub 2017 Apr 17.

2.

Human γ-Glutamyl Transpeptidase 1: STRUCTURES OF THE FREE ENZYME, INHIBITOR-BOUND TETRAHEDRAL TRANSITION STATES, AND GLUTAMATE-BOUND ENZYME REVEAL NOVEL MOVEMENT WITHIN THE ACTIVE SITE DURING CATALYSIS.

Terzyan SS, Burgett AW, Heroux A, Smith CA, Mooers BH, Hanigan MH.

J Biol Chem. 2015 Jul 10;290(28):17576-86. doi: 10.1074/jbc.M115.659680. Epub 2015 May 26.

3.

Detection of distinct glycosylation patterns on human γ-glutamyl transpeptidase 1 using antibody-lectin sandwich array (ALSA) technology.

West MB, Partyka K, Feasley CL, Maupin KA, Goppallawa I, West CM, Haab BB, Hanigan MH.

BMC Biotechnol. 2014 Dec 6;14:101. doi: 10.1186/s12896-014-0101-0.

4.

Immunolabeling of gamma-glutamyl transferase 5 in normal human tissues reveals that expression and localization differ from gamma-glutamyl transferase 1.

Hanigan MH, Gillies EM, Wickham S, Wakeham N, Wirsig-Wiechmann CR.

Histochem Cell Biol. 2015 May;143(5):505-15. doi: 10.1007/s00418-014-1295-x. Epub 2014 Nov 7.

5.

Gamma-glutamyl transpeptidase: redox regulation and drug resistance.

Hanigan MH.

Adv Cancer Res. 2014;122:103-41. doi: 10.1016/B978-0-12-420117-0.00003-7. Review.

6.

Novel insights into eukaryotic γ-glutamyltranspeptidase 1 from the crystal structure of the glutamate-bound human enzyme.

West MB, Chen Y, Wickham S, Heroux A, Cahill K, Hanigan MH, Mooers BH.

J Biol Chem. 2013 Nov 1;288(44):31902-13. doi: 10.1074/jbc.M113.498139. Epub 2013 Sep 18. Erratum in: J Biol Chem. 2014 Apr 18;289(16):11569.

7.

Human GGT2 does not autocleave into a functional enzyme: A cautionary tale for interpretation of microarray data on redox signaling.

West MB, Wickham S, Parks EE, Sherry DM, Hanigan MH.

Antioxid Redox Signal. 2013 Dec 1;19(16):1877-88. doi: 10.1089/ars.2012.4997. Epub 2013 Jun 28.

8.

Inhibition of human γ-glutamyl transpeptidase: development of more potent, physiologically relevant, uncompetitive inhibitors.

Wickham S, Regan N, West MB, Thai J, Cook PF, Terzyan SS, Li PK, Hanigan MH.

Biochem J. 2013 Mar 15;450(3):547-57. doi: 10.1042/BJ20121435.

9.

Food and Chemical Toxicology, 2011, 'Possible role of cysteine-S-conjugate β-lyase in species differences in cisplatin nephrotoxicity', R. Katayama, S. Nagata, H. Iida, N. Yamagishi, T. Yamashita, K. Furuhama.

Cooper AJ, Hanigan MH.

Food Chem Toxicol. 2011 Dec;49(12):3279-80. doi: 10.1016/j.fct.2011.08.021. Epub 2011 Sep 10. No abstract available.

PMID:
21925563
10.

Divergent effects of compounds on the hydrolysis and transpeptidation reactions of γ-glutamyl transpeptidase.

Wickham S, Regan N, West MB, Kumar VP, Thai J, Li PK, Cook PF, Hanigan MH.

J Enzyme Inhib Med Chem. 2012 Aug;27(4):476-89. doi: 10.3109/14756366.2011.597748. Epub 2011 Aug 24.

11.

Autocatalytic cleavage of human gamma-glutamyl transpeptidase is highly dependent on N-glycosylation at asparagine 95.

West MB, Wickham S, Quinalty LM, Pavlovicz RE, Li C, Hanigan MH.

J Biol Chem. 2011 Aug 19;286(33):28876-88. doi: 10.1074/jbc.M111.248823. Epub 2011 Jun 28.

12.

Gamma-glutamyl compounds: substrate specificity of gamma-glutamyl transpeptidase enzymes.

Wickham S, West MB, Cook PF, Hanigan MH.

Anal Biochem. 2011 Jul 15;414(2):208-14. doi: 10.1016/j.ab.2011.03.026. Epub 2011 Mar 27.

13.

Optimizing chemotherapy: concomitant medication lists.

Hanigan MH, Dela Cruz BL, Shord SS, Medina PJ, Fazili J, Thompson DM.

Clin Pharmacol Ther. 2011 Jan;89(1):114-9. doi: 10.1038/clpt.2010.253. Epub 2010 Dec 1.

14.

γ-Glutamyl transpeptidase is a heavily N-glycosylated heterodimer in HepG2 cells.

West MB, Hanigan MH.

Arch Biochem Biophys. 2010 Dec 15;504(2):177-81. doi: 10.1016/j.abb.2010.08.019. Epub 2010 Sep 8.

15.

N-Acetylcysteine interacts with copper to generate hydrogen peroxide and selectively induce cancer cell death.

Zheng J, Lou JR, Zhang XX, Benbrook DM, Hanigan MH, Lind SE, Ding WQ.

Cancer Lett. 2010 Dec 8;298(2):186-94. doi: 10.1016/j.canlet.2010.07.003. Epub 2010 Jul 27.

16.

Analysis of site-specific glycosylation of renal and hepatic γ-glutamyl transpeptidase from normal human tissue.

West MB, Segu ZM, Feasley CL, Kang P, Klouckova I, Li C, Novotny MV, West CM, Mechref Y, Hanigan MH.

J Biol Chem. 2010 Sep 17;285(38):29511-24. doi: 10.1074/jbc.M110.145938. Epub 2010 Jul 9.

17.

Possible role of mammography in increased incidence of breast cancer not considered.

Hanigan MH.

Arch Intern Med. 2009 May 25;169(10):998-9. doi: 10.1001/archinternmed.2009.93. No abstract available.

PMID:
19468098
18.

A novel, species-specific class of uncompetitive inhibitors of gamma-glutamyl transpeptidase.

King JB, West MB, Cook PF, Hanigan MH.

J Biol Chem. 2009 Apr 3;284(14):9059-65. doi: 10.1074/jbc.M809608200. Epub 2009 Feb 9.

19.

Over-the-counter medications and cancer patients: growing awareness of drug-drug interactions.

Hanigan MH.

Expert Opin Drug Metab Toxicol. 2009 Feb;5(2):105-7. doi: 10.1517/17425250802685233 . No abstract available.

PMID:
19199376
20.

Metabolism of cisplatin to a nephrotoxin.

Hanigan MH, Townsend DM, Cooper AJ.

Toxicology. 2009 Mar 29;257(3):174-5; author reply 176-7. doi: 10.1016/j.tox.2008.12.014. Epub 2008 Dec 24. No abstract available.

21.

Human papillomavirus 16 E5 induces bi-nucleated cell formation by cell-cell fusion.

Hu L, Plafker K, Vorozhko V, Zuna RE, Hanigan MH, Gorbsky GJ, Plafker SM, Angeletti PC, Ceresa BP.

Virology. 2009 Feb 5;384(1):125-34. doi: 10.1016/j.virol.2008.10.011. Epub 2008 Nov 28.

22.

Role of glutathione S-transferase Pi in cisplatin-induced nephrotoxicity.

Townsend DM, Tew KD, He L, King JB, Hanigan MH.

Biomed Pharmacother. 2009 Feb;63(2):79-85. doi: 10.1016/j.biopha.2008.08.004. Epub 2008 Sep 7.

23.

Use of prescription and nonprescription medications and supplements by cancer patients during chemotherapy: questionnaire validation.

Hanigan MH, Dela Cruz BL, Thompson DM, Farmer KC, Medina PJ.

J Oncol Pharm Pract. 2008 Sep;14(3):123-30. doi: 10.1177/1078155208090624. Erratum in: J Oncol Pharm Pract. 2008 Dec;14(4):233.

24.

Human tumor antigens Tn and sialyl Tn arise from mutations in Cosmc.

Ju T, Lanneau GS, Gautam T, Wang Y, Xia B, Stowell SR, Willard MT, Wang W, Xia JY, Zuna RE, Laszik Z, Benbrook DM, Hanigan MH, Cummings RD.

Cancer Res. 2008 Mar 15;68(6):1636-46. doi: 10.1158/0008-5472.CAN-07-2345. Erratum in: Cancer Res. 2008 Apr 15;68(8):3076.

25.

Cisplatin nephrotoxicity: molecular mechanisms.

Hanigan MH, Devarajan P.

Cancer Ther. 2003;1:47-61.

26.
27.

Effect of concurrent medications on cisplatin-induced nephrotoxicity in patients with head and neck cancer.

Shord SS, Thompson DM, Krempl GA, Hanigan MH.

Anticancer Drugs. 2006 Feb;17(2):207-15.

PMID:
16428940
28.

Endogenous S-nitrosoglutathione modifies 5-lipoxygenase expression in airway epithelial cells.

Zaman K, Hanigan MH, Smith A, Vaughan J, Macdonald T, Jones DR, Hunt JF, Gaston B.

Am J Respir Cell Mol Biol. 2006 Apr;34(4):387-93. Epub 2006 Jan 13.

29.

Sphingosine-1-phosphate lyase regulates sensitivity of human cells to select chemotherapy drugs in a p38-dependent manner.

Min J, Van Veldhoven PP, Zhang L, Hanigan MH, Alexander H, Alexander S.

Mol Cancer Res. 2005 May;3(5):287-96.

30.

Sphingosine kinase regulates the sensitivity of Dictyostelium discoideum cells to the anticancer drug cisplatin.

Min J, Traynor D, Stegner AL, Zhang L, Hanigan MH, Alexander H, Alexander S.

Eukaryot Cell. 2005 Jan;4(1):178-89.

31.

Stress response inhibits the nephrotoxicity of cisplatin.

Hanigan MH, Deng M, Zhang L, Taylor PT Jr, Lapus MG.

Am J Physiol Renal Physiol. 2005 Jan;288(1):F125-32. Epub 2004 Sep 7.

32.

High pressure liquid chromatography and mass spectrometry characterization of the nephrotoxic biotransformation products of Cisplatin.

Townsend DM, Marto JA, Deng M, Macdonald TJ, Hanigan MH.

Drug Metab Dispos. 2003 Jun;31(6):705-13.

33.

Role of cysteine S-conjugate beta-lyase in the metabolism of cisplatin.

Zhang L, Hanigan MH.

J Pharmacol Exp Ther. 2003 Sep;306(3):988-94. Epub 2003 May 15.

PMID:
12750429
34.

Metabolism of Cisplatin to a nephrotoxin in proximal tubule cells.

Townsend DM, Deng M, Zhang L, Lapus MG, Hanigan MH.

J Am Soc Nephrol. 2003 Jan;14(1):1-10.

36.

Gamma-glutamyl transpeptidase-deficient mice are resistant to the nephrotoxic effects of cisplatin.

Hanigan MH, Lykissa ED, Townsend DM, Ou CN, Barrios R, Lieberman MW.

Am J Pathol. 2001 Nov;159(5):1889-94.

37.

Human germ cell tumours: expression of gamma-glutamyl transpeptidase and sensitivity to cisplatin.

Hanigan MH, Frierson HF Jr, Abeler VM, Kaern J, Taylor PT Jr.

Br J Cancer. 1999 Sep;81(1):75-9.

38.

Gamma-glutamyl transpeptidase accelerates tumor growth and increases the resistance of tumors to cisplatin in vivo.

Hanigan MH, Gallagher BC, Townsend DM, Gabarra V.

Carcinogenesis. 1999 Apr;20(4):553-9.

39.

Altered expression of gamma-glutamyl transpeptidase in human tumors.

Hanigan MH, Frierson HF Jr, Swanson PE, De Young BR.

Hum Pathol. 1999 Mar;30(3):300-5.

PMID:
10088549
41.
42.

gamma-Glutamyl transpeptidase, a glutathionase: its expression and function in carcinogenesis.

Hanigan MH.

Chem Biol Interact. 1998 Apr 24;111-112:333-42. Review.

PMID:
9679564
43.

Association between expression of glutathione-associated enzymes and response to platinum-based chemotherapy in head and neck cancer.

Nishimura T, Newkirk K, Sessions RB, Andrews PA, Trock BJ, Rusmussen AA, Montogomery EA, Bischoff EK, Hanigan MH, Cullen KJ.

Chem Biol Interact. 1998 Apr 24;111-112:187-98.

PMID:
9679554
44.

Gamma-glutamyl transpeptidase immunoreactivity in benign and malignant breast tissue.

Durham JR, Frierson HF Jr, Hanigan MH.

Breast Cancer Res Treat. 1997 Aug;45(1):55-62.

PMID:
9285117
45.

gamma-Glutamyl transpeptidase in normal and neoplastic prostate glands.

Frierson HF Jr, Theodorescu D, Mills SE, Hanigan MH.

Mod Pathol. 1997 Jan;10(1):1-6.

PMID:
9021720
46.

Immunohistochemical detection of gamma-glutamyl transpeptidase in normal human tissue.

Hanigan MH, Frierson HF Jr.

J Histochem Cytochem. 1996 Oct;44(10):1101-8.

PMID:
8813074
47.

Automated immunohistochemical assay for estrogen receptor status in breast cancer using monoclonal antibody CC4-5 on the Ventana ES.

Nichols GE, Frierson HF Jr, Boyd JC, Hanigan MH.

Am J Clin Pathol. 1996 Sep;106(3):332-8.

PMID:
8816590
48.
50.

Inhibition of gamma-glutamyl transpeptidase activity by acivicin in vivo protects the kidney from cisplatin-induced toxicity.

Hanigan MH, Gallagher BC, Taylor PT Jr, Large MK.

Cancer Res. 1994 Nov 15;54(22):5925-9.

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