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Items: 18


Regulation of myofilament force and loaded shortening by skeletal myosin binding protein C.

Robinett JC, Hanft LM, Geist J, Kontrogianni-Konstantopoulos A, McDonald KS.

J Gen Physiol. 2019 Jan 31. pii: jgp.201812200. doi: 10.1085/jgp.201812200. [Epub ahead of print]


Regulating myofilament power: The determinant of health.

Hanft LM, McDonald KS.

Arch Biochem Biophys. 2019 Mar 15;663:160-164. doi: 10.1016/ Epub 2019 Jan 10. Review. No abstract available.


Cardiac myofibrillar contractile properties during the progression from hypertension to decompensated heart failure.

Hanft LM, Emter CA, McDonald KS.

Am J Physiol Heart Circ Physiol. 2017 Jul 1;313(1):H103-H113. doi: 10.1152/ajpheart.00069.2017. Epub 2017 Apr 28.


Molecule specific effects of PKA-mediated phosphorylation on rat isolated heart and cardiac myofibrillar function.

Hanft LM, Cornell TD, McDonald CA, Rovetto MJ, Emter CA, McDonald KS.

Arch Biochem Biophys. 2016 Jul 1;601:22-31. doi: 10.1016/ Epub 2016 Feb 15.


Attenuated sarcomere lengthening of the aged murine left ventricle observed using two-photon fluorescence microscopy.

Nance ME, Whitfield JT, Zhu Y, Gibson AK, Hanft LM, Campbell KS, Meininger GA, McDonald KS, Segal SS, Domeier TL.

Am J Physiol Heart Circ Physiol. 2015 Sep;309(5):H918-25. doi: 10.1152/ajpheart.00315.2015. Epub 2015 Jul 24.


Elevated Ca2+ transients and increased myofibrillar power generation cause cardiac hypercontractility in a model of Noonan syndrome with multiple lentigines.

Clay SA, Domeier TL, Hanft LM, McDonald KS, Krenz M.

Am J Physiol Heart Circ Physiol. 2015 May 1;308(9):H1086-95. doi: 10.1152/ajpheart.00501.2014. Epub 2015 Feb 27.


Dantrolene suppresses spontaneous Ca2+ release without altering excitation-contraction coupling in cardiomyocytes of aged mice.

Domeier TL, Roberts CJ, Gibson AK, Hanft LM, McDonald KS, Segal SS.

Am J Physiol Heart Circ Physiol. 2014 Sep 15;307(6):H818-29. doi: 10.1152/ajpheart.00287.2014. Epub 2014 Jul 18.


Titin-mediated control of cardiac myofibrillar function.

Hanft LM, Greaser ML, McDonald KS.

Arch Biochem Biophys. 2014 Jun 15;552-553:83-91. doi: 10.1016/ Epub 2013 Nov 20.


Length dependence of striated muscle force generation is controlled by phosphorylation of cTnI at serines 23/24.

Hanft LM, Biesiadecki BJ, McDonald KS.

J Physiol. 2013 Sep 15;591(18):4535-47. doi: 10.1113/jphysiol.2013.258400. Epub 2013 Jul 8.


Heart failure with preserved ejection fraction: chronic low-intensity interval exercise training preserves myocardial O2 balance and diastolic function.

Marshall KD, Muller BN, Krenz M, Hanft LM, McDonald KS, Dellsperger KC, Emter CA.

J Appl Physiol (1985). 2013 Jan 1;114(1):131-47. doi: 10.1152/japplphysiol.01059.2012. Epub 2012 Oct 25.


Length and PKA Dependence of Force Generation and Loaded Shortening in Porcine Cardiac Myocytes.

McDonald KS, Hanft LM, Domeier TL, Emter CA.

Biochem Res Int. 2012;2012:371415. doi: 10.1155/2012/371415. Epub 2012 Jul 5.


Protein kinase C depresses cardiac myocyte power output and attenuates myofilament responses induced by protein kinase A.

Hinken AC, Hanft LM, Scruggs SB, Sadayappan S, Robbins J, Solaro RJ, McDonald KS.

J Muscle Res Cell Motil. 2012 Dec;33(6):439-48. doi: 10.1007/s10974-012-9294-9. Epub 2012 Apr 22.


Length dependence of force generation exhibit similarities between rat cardiac myocytes and skeletal muscle fibres.

Hanft LM, McDonald KS.

J Physiol. 2010 Aug 1;588(Pt 15):2891-903. doi: 10.1113/jphysiol.2010.190504. Epub 2010 Jun 7.


TEAD-1 overexpression in the mouse heart promotes an age-dependent heart dysfunction.

Tsika RW, Ma L, Kehat I, Schramm C, Simmer G, Morgan B, Fine DM, Hanft LM, McDonald KS, Molkentin JD, Krenz M, Yang S, Ji J.

J Biol Chem. 2010 Apr 30;285(18):13721-35. doi: 10.1074/jbc.M109.063057. Epub 2010 Mar 1.


Sarcomere length dependence of power output is increased after PKA treatment in rat cardiac myocytes.

Hanft LM, McDonald KS.

Am J Physiol Heart Circ Physiol. 2009 May;296(5):H1524-31. doi: 10.1152/ajpheart.00864.2008. Epub 2009 Feb 27.


Cardiac function and modulation of sarcomeric function by length.

Hanft LM, Korte FS, McDonald KS.

Cardiovasc Res. 2008 Mar 1;77(4):627-36. Epub 2007 Dec 12. Review.


Cytoplasmic gamma-actin expression in diverse animal models of muscular dystrophy.

Hanft LM, Bogan DJ, Mayer U, Kaufman SJ, Kornegay JN, Ervasti JM.

Neuromuscul Disord. 2007 Jul;17(7):569-74. Epub 2007 May 1.


Cytoplasmic gamma-actin contributes to a compensatory remodeling response in dystrophin-deficient muscle.

Hanft LM, Rybakova IN, Patel JR, Rafael-Fortney JA, Ervasti JM.

Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5385-90. Epub 2006 Mar 24.

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