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Items: 1 to 50 of 95

1.

Nanomaterials in the Environment: Behavior, Fate, Bioavailability, and Effects-An Updated Review.

Lead JR, Batley GE, Alvarez PJJ, Croteau MN, Handy RD, McLaughlin MJ, Judy JD, Schirmer K.

Environ Toxicol Chem. 2018 Apr 6. doi: 10.1002/etc.4147. [Epub ahead of print] Review.

PMID:
29633323
2.

Antifungal properties and biocompatibility of silver nanoparticle coatings on silicone maxillofacial prostheses in vitro.

Meran Z, Besinis A, De Peralta T, Handy RD.

J Biomed Mater Res B Appl Biomater. 2018 Apr;106(3):1038-1051. doi: 10.1002/jbm.b.33917. Epub 2017 May 10.

PMID:
29524329
3.

Low hazard of silver nanoparticles and silver nitrate to the haematopoietic system of rainbow trout.

Clark NJ, Shaw BJ, Handy RD.

Ecotoxicol Environ Saf. 2018 May 15;152:121-131. doi: 10.1016/j.ecoenv.2018.01.030. Epub 2018 Feb 4.

PMID:
29407778
4.

Intravenous injection of unfunctionalized carbon-based nanomaterials confirms the minimal toxicity observed in aqueous and dietary exposures in juvenile rainbow trout (Oncorhynchus mykiss).

Boyle D, Sutton PA, Handy RD, Henry TB.

Environ Pollut. 2018 Jan;232:191-199. doi: 10.1016/j.envpol.2017.09.033. Epub 2017 Sep 20.

PMID:
28941714
5.

Sub-lethal effects of waterborne exposure to copper nanoparticles compared to copper sulphate on the shore crab (Carcinus maenas).

Rossbach LM, Shaw BJ, Piegza D, Vevers WF, Atfield AJ, Handy RD.

Aquat Toxicol. 2017 Oct;191:245-255. doi: 10.1016/j.aquatox.2017.08.006. Epub 2017 Aug 10.

PMID:
28888166
6.

Antibacterial activity and biofilm inhibition by surface modified titanium alloy medical implants following application of silver, titanium dioxide and hydroxyapatite nanocoatings.

Besinis A, Hadi SD, Le HR, Tredwin C, Handy RD.

Nanotoxicology. 2017 Apr;11(3):327-338. doi: 10.1080/17435390.2017.1299890. Epub 2017 Mar 17.

PMID:
28281851
7.

A critical evaluation of the fish early-life stage toxicity test for engineered nanomaterials: experimental modifications and recommendations.

Shaw BJ, Liddle CC, Windeatt KM, Handy RD.

Arch Toxicol. 2016 Sep;90(9):2077-107. doi: 10.1007/s00204-016-1734-7. Epub 2016 Jun 18. Review.

PMID:
27318802
8.

Nanomaterials in the aquatic environment: A European Union-United States perspective on the status of ecotoxicity testing, research priorities, and challenges ahead.

Selck H, Handy RD, Fernandes TF, Klaine SJ, Petersen EJ.

Environ Toxicol Chem. 2016 May;35(5):1055-67. doi: 10.1002/etc.3385. Review.

9.

Sublethal effects of copper sulphate compared to copper nanoparticles in rainbow trout (Oncorhynchus mykiss) at low pH: physiology and metal accumulation.

Al-Bairuty GA, Boyle D, Henry TB, Handy RD.

Aquat Toxicol. 2016 May;174:188-98. doi: 10.1016/j.aquatox.2016.02.006. Epub 2016 Feb 17.

PMID:
26966873
10.

The acute toxicity of thallium to freshwater organisms: Implications for risk assessment.

Tatsi K, Turner A, Handy RD, Shaw BJ.

Sci Total Environ. 2015 Dec 1;536:382-390. doi: 10.1016/j.scitotenv.2015.06.069. Epub 2015 Jul 28.

PMID:
26225743
11.

Review of nanomaterials in dentistry: interactions with the oral microenvironment, clinical applications, hazards, and benefits.

Besinis A, De Peralta T, Tredwin CJ, Handy RD.

ACS Nano. 2015 Mar 24;9(3):2255-89. doi: 10.1021/nn505015e. Epub 2015 Feb 12. Review.

PMID:
25625290
12.

Comparison of intermittent and continuous exposures to inorganic mercury in the mussel, Mytilus edulis: accumulation and sub-lethal physiological effects.

Amachree D, Moody AJ, Handy RD.

Ecotoxicol Environ Saf. 2014 Nov;109:133-42. doi: 10.1016/j.ecoenv.2014.07.025. Epub 2014 Aug 30.

PMID:
25178526
13.

Effects of metal nanoparticles on the lateral line system and behaviour in early life stages of zebrafish (Danio rerio).

McNeil PL, Boyle D, Henry TB, Handy RD, Sloman KA.

Aquat Toxicol. 2014 Jul;152:318-23. doi: 10.1016/j.aquatox.2014.04.022. Epub 2014 Apr 25.

PMID:
24813264
14.

Impaired behavioural response to alarm substance in rainbow trout exposed to copper nanoparticles.

Sovová T, Boyle D, Sloman KA, Vanegas Pérez C, Handy RD.

Aquat Toxicol. 2014 Jul;152:195-204. doi: 10.1016/j.aquatox.2014.04.003. Epub 2014 Apr 13.

15.

Uptake of different crystal structures of TiO₂ nanoparticles by Caco-2 intestinal cells.

Gitrowski C, Al-Jubory AR, Handy RD.

Toxicol Lett. 2014 May 2;226(3):264-76. doi: 10.1016/j.toxlet.2014.02.014. Epub 2014 Feb 25.

16.

Effects of silver nanoparticles (NM-300K) on Lumbricus rubellus earthworms and particle characterization in relevant test matrices including soil.

van der Ploeg MJ, Handy RD, Waalewijn-Kool PL, van den Berg JH, Herrera Rivera ZE, Bovenschen J, Molleman B, Baveco JM, Tromp P, Peters RJ, Koopmans GF, Rietjens IM, van den Brink NW.

Environ Toxicol Chem. 2014 Apr;33(4):743-52. doi: 10.1002/etc.2487.

PMID:
24318461
17.

Minimal effects of waterborne exposure to single-walled carbon nanotubes on behaviour and physiology of juvenile rainbow trout (Oncorhynchus mykiss).

Boyle D, Fox JE, Akerman JM, Sloman KA, Henry TB, Handy RD.

Aquat Toxicol. 2014 Jan;146:154-64. doi: 10.1016/j.aquatox.2013.11.006. Epub 2013 Nov 18.

PMID:
24308918
18.

Uptake epithelia behave in a cell-centric and not systems homeostatic manner in response to zinc depletion and supplementation.

Zheng D, Feeney GP, Handy RD, Hogstrand C, Kille P.

Metallomics. 2014 Jan;6(1):154-65. doi: 10.1039/c3mt00212h.

19.

Critical comparison of intravenous injection of TiO2 nanoparticles with waterborne and dietary exposures concludes minimal environmentally-relevant toxicity in juvenile rainbow trout Oncorhynchus mykiss.

Boyle D, Al-Bairuty GA, Henry TB, Handy RD.

Environ Pollut. 2013 Nov;182:70-9. doi: 10.1016/j.envpol.2013.07.001. Epub 2013 Jul 27.

PMID:
23896679
20.

Inhibition of biofilm formation and antibacterial properties of a silver nano-coating on human dentine.

Besinis A, De Peralta T, Handy RD.

Nanotoxicology. 2014 Nov;8(7):745-54. doi: 10.3109/17435390.2013.825343. Epub 2013 Aug 7.

PMID:
23875717
21.

Biological impact assessment of nanomaterial used in nanomedicine. introduction to the NanoTEST project.

Juillerat-Jeanneret L, Dusinska M, Fjellsbø LM, Collins AR, Handy RD, Riediker M; NanoTEST Consortium.

Nanotoxicology. 2015 May;9 Suppl 1:5-12. doi: 10.3109/17435390.2013.826743. Epub 2013 Sep 16.

PMID:
23875681
22.

Health effects of selected nanoparticles in vivo: liver function and hepatotoxicity following intravenous injection of titanium dioxide and Na-oleate-coated iron oxide nanoparticles in rodents.

Volkovova K, Handy RD, Staruchova M, Tulinska J, Kebis A, Pribojova J, Ulicna O, Kucharská J, Dusinska M.

Nanotoxicology. 2015 May;9 Suppl 1:95-105. doi: 10.3109/17435390.2013.815285.

PMID:
23763576
23.

Comparison of intermittent and continuous exposures to cadmium in the blue mussel, Mytilus edulis: accumulation and sub-lethal physiological effects.

Amachree D, Moody AJ, Handy RD.

Ecotoxicol Environ Saf. 2013 Sep;95:19-26. doi: 10.1016/j.ecoenv.2013.04.023. Epub 2013 Jun 6.

PMID:
23747128
24.

Towards a Consensus View on Understanding Nanomaterials Hazards and Managing Exposure: Knowledge Gaps and Recommendations.

Hunt G, Lynch I, Cassee F, Handy RD, Fernandes TF, Berges M, Kuhlbusch TAJ, Dusinska M, Riediker M.

Materials (Basel). 2013 Mar 20;6(3):1090-1117. doi: 10.3390/ma6031090.

25.

A simplified method for determining titanium from TiO2 nanoparticles in fish tissue with a concomitant multi-element analysis.

Shaw BJ, Ramsden CS, Turner A, Handy RD.

Chemosphere. 2013 Aug;92(9):1136-44. doi: 10.1016/j.chemosphere.2013.01.065. Epub 2013 Mar 7.

PMID:
23473697
26.

Effect of pollution history on immunological responses and organ histology in the marine mussel Mytilus edulis exposed to cadmium.

Sheir SK, Handy RD, Henry TB.

Arch Environ Contam Toxicol. 2013 May;64(4):701-16. doi: 10.1007/s00244-012-9868-y. Epub 2013 Jan 24.

PMID:
23344845
27.

Ingestion of metal-nanoparticle contaminated food disrupts endogenous microbiota in zebrafish (Danio rerio).

Merrifield DL, Shaw BJ, Harper GM, Saoud IP, Davies SJ, Handy RD, Henry TB.

Environ Pollut. 2013 Mar;174:157-63. doi: 10.1016/j.envpol.2012.11.017. Epub 2012 Dec 20.

PMID:
23262071
28.

Subtle alterations in swimming speed distributions of rainbow trout exposed to titanium dioxide nanoparticles are associated with gill rather than brain injury.

Boyle D, Al-Bairuty GA, Ramsden CS, Sloman KA, Henry TB, Handy RD.

Aquat Toxicol. 2013 Jan 15;126:116-27. doi: 10.1016/j.aquatox.2012.10.006. Epub 2012 Oct 17.

PMID:
23178178
29.

Histopathological effects of waterborne copper nanoparticles and copper sulphate on the organs of rainbow trout (Oncorhynchus mykiss).

Al-Bairuty GA, Shaw BJ, Handy RD, Henry TB.

Aquat Toxicol. 2013 Jan 15;126:104-15. doi: 10.1016/j.aquatox.2012.10.005. Epub 2012 Oct 13.

PMID:
23174144
30.
31.

Sub-lethal effects of titanium dioxide nanoparticles on the physiology and reproduction of zebrafish.

Ramsden CS, Henry TB, Handy RD.

Aquat Toxicol. 2013 Jan 15;126:404-13. doi: 10.1016/j.aquatox.2012.08.021. Epub 2012 Sep 7.

PMID:
23084046
32.

Uptake of titanium from TiO₂ nanoparticle exposure in the isolated perfused intestine of rainbow trout: nystatin, vanadate and novel CO₂-sensitive components.

Al-Jubory AR, Handy RD.

Nanotoxicology. 2013 Dec;7(8):1282-301. doi: 10.3109/17435390.2012.735268. Epub 2012 Oct 30.

PMID:
23020080
33.

Dietary preference and feeding selectivity of common dragonet Callionymus lyra in U.K.

Griffin R, Pearce B, Handy RD.

J Fish Biol. 2012 Aug;81(3):1019-31. doi: 10.1111/j.1095-8649.2012.03375.x.

PMID:
22880734
34.

Effects of waterborne copper nanoparticles and copper sulphate on rainbow trout, (Oncorhynchus mykiss): physiology and accumulation.

Shaw BJ, Al-Bairuty G, Handy RD.

Aquat Toxicol. 2012 Jul 15;116-117:90-101. doi: 10.1016/j.aquatox.2012.02.032. Epub 2012 Mar 5.

PMID:
22480992
35.

Practical considerations for conducting ecotoxicity test methods with manufactured nanomaterials: what have we learnt so far?

Handy RD, van den Brink N, Chappell M, Mühling M, Behra R, Dušinská M, Simpson P, Ahtiainen J, Jha AN, Seiter J, Bednar A, Kennedy A, Fernandes TF, Riediker M.

Ecotoxicology. 2012 May;21(4):933-72. doi: 10.1007/s10646-012-0862-y. Epub 2012 Mar 16. Review.

36.

C60 exposure induced tissue damage and gene expression alterations in the earthworm Lumbricus rubellus.

Van Der Ploeg MJ, Handy RD, Heckmann LH, Van Der Hout A, Van Den Brink NW.

Nanotoxicology. 2013 Jun;7(4):432-40. doi: 10.3109/17435390.2012.668569. Epub 2012 Mar 20.

PMID:
22394349
37.

Effect of nanomaterials on the compound action potential of the shore crab, Carcinus maenas.

Windeatt KM, Handy RD.

Nanotoxicology. 2013 Jun;7(4):378-88. doi: 10.3109/17435390.2012.663809. Epub 2012 Mar 6.

PMID:
22394242
38.

Are reproduction impairments of free spawning marine invertebrates exposed to zero-valent nano-iron associated with dissolution of nanoparticles?

Kadar E, Dyson O, Handy RD, Al-Subiai SN.

Nanotoxicology. 2013 Mar;7(2):135-43. doi: 10.3109/17435390.2011.647927. Epub 2012 Jan 20.

PMID:
22263896
39.

Paradigms to assess the environmental impact of manufactured nanomaterials.

Klaine SJ, Koelmans AA, Horne N, Carley S, Handy RD, Kapustka L, Nowack B, von der Kammer F.

Environ Toxicol Chem. 2012 Jan;31(1):3-14. doi: 10.1002/etc.733. No abstract available.

PMID:
22162122
40.

Ecotoxicity test methods for engineered nanomaterials: practical experiences and recommendations from the bench.

Handy RD, Cornelis G, Fernandes T, Tsyusko O, Decho A, Sabo-Attwood T, Metcalfe C, Steevens JA, Klaine SJ, Koelmans AA, Horne N.

Environ Toxicol Chem. 2012 Jan;31(1):15-31. doi: 10.1002/etc.706. Epub 2011 Nov 18. Review.

PMID:
22002667
41.

Effects of manufactured nanomaterials on fishes: a target organ and body systems physiology approach.

Handy RD, Al-Bairuty G, Al-Jubory A, Ramsden CS, Boyle D, Shaw BJ, Henry TB.

J Fish Biol. 2011 Oct;79(4):821-53. doi: 10.1111/j.1095-8649.2011.03080.x. Review.

PMID:
21967577
42.

Physiological effects of nanoparticles on fish: a comparison of nanometals versus metal ions.

Shaw BJ, Handy RD.

Environ Int. 2011 Aug;37(6):1083-97. doi: 10.1016/j.envint.2011.03.009. Epub 2011 Apr 6. Review.

PMID:
21474182
43.

Dietary toxicity of single-walled carbon nanotubes and fullerenes (C60) in rainbow trout (Oncorhynchus mykiss).

Fraser TW, Reinardy HC, Shaw BJ, Henry TB, Handy RD.

Nanotoxicology. 2011 Mar;5(1):98-108. doi: 10.3109/17435390.2010.502978. Epub 2010 Jul 15.

PMID:
21417691
44.

Limited DNA damage in human endothelial cells after hyperbaric oxygen treatment and protection from subsequent hydrogen peroxide exposure.

Yuan J, Handy RD, Moody AJ, Smerdon G, Bryson P.

Biochim Biophys Acta. 2011 May;1810(5):526-31. doi: 10.1016/j.bbagen.2011.02.007. Epub 2011 Mar 1.

PMID:
21371529
45.

Endosulfan affects health variables in adult zebrafish (Danio rerio) and induces alterations in larvae development.

Velasco-Santamaría YM, Handy RD, Sloman KA.

Comp Biochem Physiol C Toxicol Pharmacol. 2011 May;153(4):372-80. doi: 10.1016/j.cbpc.2011.01.001. Epub 2011 Jan 22.

PMID:
21262389
46.

Dynamic transcriptomic profiles of zebrafish gills in response to zinc supplementation.

Zheng D, Kille P, Feeney GP, Cunningham P, Handy RD, Hogstrand C.

BMC Genomics. 2010 Oct 11;11:553. doi: 10.1186/1471-2164-11-553.

47.

Dynamic transcriptomic profiles of zebrafish gills in response to zinc depletion.

Zheng D, Kille P, Feeney GP, Cunningham P, Handy RD, Hogstrand C.

BMC Genomics. 2010 Oct 8;11:548. doi: 10.1186/1471-2164-11-548.

48.

Prey selection and functional response of juvenile lemon sharks Negaprion brevirostris.

Reeve A, Handy RD, Gruber SH.

J Fish Biol. 2009 Jul;75(1):276-81. doi: 10.1111/j.1095-8649.2009.02265.x.

PMID:
20738496
49.

Tissue injury and cellular immune responses to mercuric chloride exposure in the common mussel Mytilus edulis: modulation by lipopolysaccharide.

Sheir SK, Handy RD, Galloway TS.

Ecotoxicol Environ Saf. 2010 Sep;73(6):1338-44. doi: 10.1016/j.ecoenv.2010.01.014. Epub 2010 Jul 2.

PMID:
20598371
50.

Tissue injury and cellular immune responses to cadmium chloride exposure in the common mussel Mytilus edulis: modulation by lipopolysaccharide.

Sheir SK, Handy RD.

Arch Environ Contam Toxicol. 2010 Nov;59(4):602-13. doi: 10.1007/s00244-010-9502-9. Epub 2010 Apr 3.

PMID:
20364252

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