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Items: 29

1.

Decreased complexity of glucose dynamics in diabetes in rhesus monkeys.

Raubertas R, Beech J, Watson W, Fox S, Tiesma S, Gilberto DB, Bone A, Rebbeck PA, Gantert LT, Conarello S, Knapp W, Gray T, Handt L, Li C.

Sci Rep. 2019 Feb 5;9(1):1438. doi: 10.1038/s41598-018-36776-4.

2.

Differential anti-thrombotic benefit and bleeding risk profiles of antagonists of protease-activated receptor 1 and 4 in Cynomolgus Macaques.

Wickham LA, Sitko G, Stranieri-Michener M, Handt L, Basso A, Fried S, Chu L, Maderia M, Owens K, Castriota G, Chen Z, Metzger JM, Imbriglio J, Wang X, Cai TQ.

Thromb Res. 2016 Sep;145:133-9. doi: 10.1016/j.thromres.2016.06.007. Epub 2016 Jun 11.

PMID:
27318768
3.

Platelet transfusion reverses bleeding evoked by triple anti-platelet therapy including vorapaxar, a novel platelet thrombin receptor antagonist.

Cai TQ, Wickham LA, Sitko G, Michener MS, Raubertas R, Handt L, Chintala M, Seiffert D, Forrest M.

Eur J Pharmacol. 2015 Jul 5;758:107-14. doi: 10.1016/j.ejphar.2015.03.073. Epub 2015 Apr 7.

PMID:
25857224
4.

Pathogenic properties of enterohepatic Helicobacter spp. isolated from rhesus macaques with intestinal adenocarcinoma.

Lertpiriyapong K, Handt L, Feng Y, Mitchell TW, Lodge KE, Shen Z, Dewhirst FE, Muthupalani S, Fox JG.

J Med Microbiol. 2014 Jul;63(Pt 7):1004-16. doi: 10.1099/jmm.0.072462-0. Epub 2014 Apr 2.

5.

Antiviral efficacy upon administration of a HepDirect prodrug of 2'-C-methylcytidine to hepatitis C virus-infected chimpanzees.

Carroll SS, Koeplinger K, Vavrek M, Zhang NR, Handt L, MacCoss M, Olsen DB, Reddy KR, Sun Z, van Poelje PD, Fujitaki JM, Boyer SH, Linemeyer DL, Hecker SJ, Erion MD.

Antimicrob Agents Chemother. 2011 Aug;55(8):3854-60. doi: 10.1128/AAC.01152-10. Epub 2011 May 31.

6.

Sustained viral response in a hepatitis C virus-infected chimpanzee via a combination of direct-acting antiviral agents.

Olsen DB, Davies ME, Handt L, Koeplinger K, Zhang NR, Ludmerer SW, Graham D, Liverton N, MacCoss M, Hazuda D, Carroll SS.

Antimicrob Agents Chemother. 2011 Feb;55(2):937-9. doi: 10.1128/AAC.00990-10. Epub 2010 Nov 29.

7.

Robust antiviral efficacy upon administration of a nucleoside analog to hepatitis C virus-infected chimpanzees.

Carroll SS, Ludmerer S, Handt L, Koeplinger K, Zhang NR, Graham D, Davies ME, MacCoss M, Hazuda D, Olsen DB.

Antimicrob Agents Chemother. 2009 Mar;53(3):926-34. doi: 10.1128/AAC.01032-08. Epub 2008 Dec 15.

8.

A pharmacokinetic study of enrofloxacin and its active metabolite ciprofloxacin after oral and intramuscular dosing of enrofloxacin in rhesus monkeys (Macaca mulatta).

Klein H, Hasselschwert D, Handt L, Kastello M.

J Med Primatol. 2008 Aug;37(4):177-83. doi: 10.1111/j.1600-0684.2008.00280.x. Epub 2008 Mar 31.

PMID:
18384536
9.

Isolation and characterization of a novel helicobacter species, "Helicobacter macacae," from rhesus monkeys with and without chronic idiopathic colitis.

Fox JG, Boutin SR, Handt LK, Taylor NS, Xu S, Rickman B, Marini RP, Dewhirst FE, Paster BJ, Motzel S, Klein HJ.

J Clin Microbiol. 2007 Dec;45(12):4061-3. Epub 2007 Oct 10.

10.

PrimaTB STAT-PAK assay, a novel, rapid lateral-flow test for tuberculosis in nonhuman primates.

Lyashchenko KP, Greenwald R, Esfandiari J, Greenwald D, Nacy CA, Gibson S, Didier PJ, Washington M, Szczerba P, Motzel S, Handt L, Pollock JM, McNair J, Andersen P, Langermans JA, Verreck F, Ervin S, Ervin F, McCombs C.

Clin Vaccine Immunol. 2007 Sep;14(9):1158-64. Epub 2007 Jul 25.

11.

Early depletion of proliferating B cells of germinal center in rapidly progressive simian immunodeficiency virus infection.

Zhang ZQ, Casimiro DR, Schleif WA, Chen M, Citron M, Davies ME, Burns J, Liang X, Fu TM, Handt L, Emini EA, Shiver JW.

Virology. 2007 May 10;361(2):455-64. Epub 2007 Jan 16.

12.

Vectored Gag and Env but not Tat show efficacy against simian-human immunodeficiency virus 89.6P challenge in Mamu-A*01-negative rhesus monkeys.

Liang X, Casimiro DR, Schleif WA, Wang F, Davies ME, Zhang ZQ, Fu TM, Finnefrock AC, Handt L, Citron MP, Heidecker G, Tang A, Chen M, Wilson KA, Gabryelski L, McElhaugh M, Carella A, Moyer C, Huang L, Vitelli S, Patel D, Lin J, Emini EA, Shiver JW.

J Virol. 2005 Oct;79(19):12321-31.

13.

Integrase inhibitors and cellular immunity suppress retroviral replication in rhesus macaques.

Hazuda DJ, Young SD, Guare JP, Anthony NJ, Gomez RP, Wai JS, Vacca JP, Handt L, Motzel SL, Klein HJ, Dornadula G, Danovich RM, Witmer MV, Wilson KA, Tussey L, Schleif WA, Gabryelski LS, Jin L, Miller MD, Casimiro DR, Emini EA, Shiver JW.

Science. 2004 Jul 23;305(5683):528-32. Epub 2004 Jul 8.

14.

The impact of early immune destruction on the kinetics of postacute viral replication in rhesus monkey infected with the simian-human immunodeficiency virus 89.6P.

Zhang ZQ, Schleif WA, Casimiro DR, Handt L, Chen M, Davies ME, Liang X, Fu TM, Tang A, Wilson KA, McElhaugh M, Carella A, Tan C, Connolly B, Hill S, Klein H, Emini EA, Shiver JW.

Virology. 2004 Mar 1;320(1):75-84.

15.

Clinical and microbiologic characterization of hemorrhagic pneumonia due to extraintestinal pathogenic Escherichia coli in four young dogs.

Handt LK, Stoffregen DA, Prescott JS, Pouch WJ, Ngai DT, Anderson CA, Gatto NT, DebRoy C, Fairbrother JM, Motzel SL, Klein HJ.

Comp Med. 2003 Dec;53(6):663-70.

PMID:
14727816
16.

Effects of inhibition of alpha-CGRP receptors on cardiac and peripheral vascular dynamics in conscious dogs with chronic heart failure.

Shen YT, Mallee JJ, Handt LK, Gilberto DB, Lynch JJ Jr, Hargreaves RJ, Koblan KS, Gould RJ, Kane SA.

J Cardiovasc Pharmacol. 2003 Nov;42(5):656-61.

PMID:
14576515
17.

Novel Techniques for Testing of Esophageal Irritancy of Liquids and Tablets in Dogs.

Smith S, Handt L, Peter C, Klein H.

Contemp Top Lab Anim Sci. 1998 May;37(3):66-69.

PMID:
12456165
18.

Mamu-A*01 allele-mediated attenuation of disease progression in simian-human immunodeficiency virus infection.

Zhang ZQ, Fu TM, Casimiro DR, Davies ME, Liang X, Schleif WA, Handt L, Tussey L, Chen M, Tang A, Wilson KA, Trigona WL, Freed DC, Tan CY, Horton M, Emini EA, Shiver JW.

J Virol. 2002 Dec;76(24):12845-54.

19.

Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity.

Shiver JW, Fu TM, Chen L, Casimiro DR, Davies ME, Evans RK, Zhang ZQ, Simon AJ, Trigona WL, Dubey SA, Huang L, Harris VA, Long RS, Liang X, Handt L, Schleif WA, Zhu L, Freed DC, Persaud NV, Guan L, Punt KS, Tang A, Chen M, Wilson KA, Collins KB, Heidecker GJ, Fernandez VR, Perry HC, Joyce JG, Grimm KM, Cook JC, Keller PM, Kresock DS, Mach H, Troutman RD, Isopi LA, Williams DM, Xu Z, Bohannon KE, Volkin DB, Montefiori DC, Miura A, Krivulka GR, Lifton MA, Kuroda MJ, Schmitz JE, Letvin NL, Caulfield MJ, Bett AJ, Youil R, Kaslow DC, Emini EA.

Nature. 2002 Jan 17;415(6869):331-5.

PMID:
11797011
20.

Novel Helicobacter species isolated from rhesus monkeys with chronic idiopathic colitis.

Fox JG, Handt L, Xu S, Shen Z, Dewhirst FE, Paster BJ, Dangler CA, Lodge K, Motzel S, Klein H.

J Med Microbiol. 2001 May;50(5):421-9.

PMID:
11339249
21.

Isolation of Helicobacter cinaedi from the colon, liver, and mesenteric lymph node of a rhesus monkey with chronic colitis and hepatitis.

Fox JG, Handt L, Sheppard BJ, Xu S, Dewhirst FE, Motzel S, Klein H.

J Clin Microbiol. 2001 Apr;39(4):1580-5.

22.

Insulin-like growth factor-1 and growth hormone (GH) levels in canine cerebrospinal fluid are unaffected by GH or GH secretagogue (MK-0677) administration.

Prahalada S, Block G, Handt L, DeBurlet G, Cahill M, Hoe CM, van Zwieten MJ.

Horm Metab Res. 1999 Feb-Mar;31(2-3):133-7.

PMID:
10226793
23.

Esophageal irritation due to alendronate sodium tablets: possible mechanisms.

Peter CP, Handt LK, Smith SM.

Dig Dis Sci. 1998 Sep;43(9):1998-2002.

PMID:
9753265
24.

Potent, protective anti-HIV immune responses generated by bimodal HIV envelope DNA plus protein vaccination.

Letvin NL, Montefiori DC, Yasutomi Y, Perry HC, Davies ME, Lekutis C, Alroy M, Freed DC, Lord CI, Handt LK, Liu MA, Shiver JW.

Proc Natl Acad Sci U S A. 1997 Aug 19;94(17):9378-83.

25.

Diagnosis of Helicobacter pylori infection in a colony of rhesus monkeys (Macaca mulatta).

Handt LK, Fox JG, Yan LL, Shen Z, Pouch WJ, Ngai D, Motzel SL, Nolan TE, Klein HJ.

J Clin Microbiol. 1997 Jan;35(1):165-8.

26.

Evaluation of two commercial serologic tests for the diagnosis of Helicobacter pylori infection in the rhesus monkey.

Handt LK, Klein HJ, Rozmiarek H, Fox JG, Pouch WJ, Motzel SL.

Lab Anim Sci. 1995 Oct;45(5):613-7. No abstract available.

PMID:
8569170
27.

Characterization of feline Helicobacter pylori strains and associated gastritis in a colony of domestic cats.

Handt LK, Fox JG, Stalis IH, Rufo R, Lee G, Linn J, Li X, Kleanthous H.

J Clin Microbiol. 1995 Sep;33(9):2280-9.

28.

Helicobacter pylori-induced gastritis in the domestic cat.

Fox JG, Batchelder M, Marini R, Yan L, Handt L, Li X, Shames B, Hayward A, Campbell J, Murphy JC.

Infect Immun. 1995 Jul;63(7):2674-81.

29.

Helicobacter pylori isolated from the domestic cat: public health implications.

Handt LK, Fox JG, Dewhirst FE, Fraser GJ, Paster BJ, Yan LL, Rozmiarek H, Rufo R, Stalis IH.

Infect Immun. 1994 Jun;62(6):2367-74. Erratum in: Infect Immun 1995 Mar;63(3):1146.

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