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Items: 1 to 50 of 69

1.

The Utility of MRI in Pediatric Trauma Patients Suspected of Having Cervical Spine Injuries.

Derderian SC, Greenan K, Mirsky DM, Stence NV, Graber S, Hankinson TC, Hubbell N, Alexander A, O'Neill BR, Wilkinson CC, Handler MH.

J Trauma Acute Care Surg. 2019 Aug 16. doi: 10.1097/TA.0000000000002487. [Epub ahead of print]

PMID:
31425496
2.

Establishment of patient-derived orthotopic xenograft model of 1q+ posterior fossa group A ependymoma.

Pierce AM, Witt DA, Donson AM, Gilani A, Sanford B, Sill M, Van Court B, Oweida A, Prince EW, Steiner J, Danis E, Dorris K, Hankinson T, Handler MH, Jones KL, Karam SD, Serkova NJ, Vibhakar R, Foreman NK, Griesinger AM.

Neuro Oncol. 2019 Jul 4. pii: noz116. doi: 10.1093/neuonc/noz116. [Epub ahead of print]

PMID:
31276586
3.

Conformal Radiation Therapy for Pediatric Ependymoma, Chemotherapy for Incompletely Resected Ependymoma, and Observation for Completely Resected, Supratentorial Ependymoma.

Merchant TE, Bendel AE, Sabin ND, Burger PC, Shaw DW, Chang E, Wu S, Zhou T, Eisenstat DD, Foreman NK, Fuller CE, Anderson ET, Hukin J, Lau CC, Pollack IF, Laningham FH, Lustig RH, Armstrong FD, Handler MH, Williams-Hughes C, Kessel S, Kocak M, Ellison DW, Ramaswamy V.

J Clin Oncol. 2019 Apr 20;37(12):974-983. doi: 10.1200/JCO.18.01765. Epub 2019 Feb 27.

PMID:
30811284
4.

Identification of FDA-Approved Oncology Drugs with Selective Potency in High-Risk Childhood Ependymoma.

Donson AM, Amani V, Warner EA, Griesinger AM, Witt DA, Levy JMM, Hoffman LM, Hankinson TC, Handler MH, Vibhakar R, Dorris K, Foreman NK.

Mol Cancer Ther. 2018 Sep;17(9):1984-1994. doi: 10.1158/1535-7163.MCT-17-1185. Epub 2018 Jun 20.

5.

Pediatric versus adult meningioma: comparison of epidemiology, treatments, and outcomes using the Surveillance, Epidemiology, and End Results database.

Dudley RWR, Torok MR, Randall S, Béland B, Handler MH, Mulcahy-Levy JM, Liu AK, Hankinson TC.

J Neurooncol. 2018 May;137(3):621-629. doi: 10.1007/s11060-018-2756-1. Epub 2018 Mar 9.

PMID:
29520612
6.

Specific expression of PD-L1 in RELA-fusion supratentorial ependymoma: Implications for PD-1-targeted therapy.

Witt DA, Donson AM, Amani V, Moreira DC, Sanford B, Hoffman LM, Handler MH, Levy JMM, Jones KL, Nellan A, Foreman NK, Griesinger AM.

Pediatr Blood Cancer. 2018 May;65(5):e26960. doi: 10.1002/pbc.26960. Epub 2018 Jan 19.

7.

Intracranial Ewing sarcoma: four pediatric examples.

Yang MJ, Whelan R, Madden J, Mulcahy Levy JM, Kleinschmidt-DeMasters BK, Hankinson TC, Foreman NK, Handler MH.

Childs Nerv Syst. 2018 Mar;34(3):441-448. doi: 10.1007/s00381-017-3684-7. Epub 2017 Dec 28.

8.

Frontal and occipital horn ratio is associated with multifocal intraparenchymal hemorrhages in neonatal shunted hydrocephalus.

Oushy S, Parker JJ, Campbell K, Palmer C, Wilkinson C, Stence NV, Handler MH, Mirsky DM.

J Neurosurg Pediatr. 2017 Nov;20(5):432-438. doi: 10.3171/2017.6.PEDS16481. Epub 2017 Sep 8.

PMID:
28885094
9.

Characterization of 2 Novel Ependymoma Cell Lines With Chromosome 1q Gain Derived From Posterior Fossa Tumors of Childhood.

Amani V, Donson AM, Lummus SC, Prince EW, Griesinger AM, Witt DA, Hankinson TC, Handler MH, Dorris K, Vibhakar R, Foreman NK, Hoffman LM.

J Neuropathol Exp Neurol. 2017 Jul 1;76(7):595-604. doi: 10.1093/jnen/nlx040.

10.

Molecular Analyses Reveal Inflammatory Mediators in the Solid Component and Cyst Fluid of Human Adamantinomatous Craniopharyngioma.

Donson AM, Apps J, Griesinger AM, Amani V, Witt DA, Anderson RCE, Niazi TN, Grant G, Souweidane M, Johnston JM, Jackson EM, Kleinschmidt-DeMasters BK, Handler MH, Tan AC, Gore L, Virasami A, Gonzalez-Meljem JM, Jacques TS, Martinez-Barbera JP, Foreman NK, Hankinson TC; Advancing Treatment for Pediatric Craniopharyngioma Consortium.

J Neuropathol Exp Neurol. 2017 Sep 1;76(9):779-788. doi: 10.1093/jnen/nlx061.

11.

NF-κB upregulation through epigenetic silencing of LDOC1 drives tumor biology and specific immunophenotype in Group A ependymoma.

Griesinger AM, Witt DA, Grob ST, Georgio Westover SR, Donson AM, Sanford B, Mulcahy Levy JM, Wong R, Moreira DC, DeSisto JA, Balakrishnan I, Hoffman LM, Handler MH, Jones KL, Vibhakar R, Venkataraman S, Foreman NK.

Neuro Oncol. 2017 Oct 1;19(10):1350-1360. doi: 10.1093/neuonc/nox061.

12.

Chordoma Occurs in Young Children With Tuberous Sclerosis.

Dahl NA, Luebbert T, Loi M, Neuberger I, Handler MH, Kleinschmidt-DeMasters BK, Mulcahy Levy JM.

J Neuropathol Exp Neurol. 2017 Jun 1;76(6):418-423. doi: 10.1093/jnen/nlx032.

13.

Insular epilepsy surgery.

Laoprasert P, Ojemann JG, Handler MH.

Epilepsia. 2017 Apr;58 Suppl 1:35-45. doi: 10.1111/epi.13682. Review.

14.

Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors.

Mulcahy Levy JM, Zahedi S, Griesinger AM, Morin A, Davies KD, Aisner DL, Kleinschmidt-DeMasters BK, Fitzwalter BE, Goodall ML, Thorburn J, Amani V, Donson AM, Birks DK, Mirsky DM, Hankinson TC, Handler MH, Green AL, Vibhakar R, Foreman NK, Thorburn A.

Elife. 2017 Jan 17;6. pii: e19671. doi: 10.7554/eLife.19671.

15.

Use of magnetic resonance imaging to detect occult spinal dysraphism in infants.

O'Neill BR, Gallegos D, Herron A, Palmer C, Stence NV, Hankinson TC, Corbett Wilkinson C, Handler MH.

J Neurosurg Pediatr. 2017 Feb;19(2):217-226. doi: 10.3171/2016.8.PEDS16128. Epub 2016 Dec 2.

PMID:
27911245
16.

Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma.

Prince EW, Balakrishnan I, Shah M, Mulcahy Levy JM, Griesinger AM, Alimova I, Harris PS, Birks DK, Donson AM, Davidson N, Remke M, Taylor MD, Handler MH, Foreman NK, Venkataraman S, Vibhakar R.

Oncotarget. 2016 Aug 16;7(33):53881-53894. doi: 10.18632/oncotarget.10692.

17.

Response to Journal Club: Pediatric Low-Grade Ganglioglioma: Epidemiology, Treatments, and Outcome Analysis of 348 Children From the Surveillance, Epidemiology, and End Results Database.

Dudley RW, Torok MR, Hoffman L, Levy JM, Handler MH, Liu AK, Hankinson TC.

Neurosurgery. 2016 Aug;79(2):309. doi: 10.1227/NEU.0000000000001275. No abstract available.

PMID:
27428632
18.

Rasmussen encephalitis tissue transfer program.

Kruse CA, Pardo CA, Hartman AL, Jallo G, Vining EP, Voros J, Gaillard WD, Liu J, Oluigbo C, Malone S, Bleasel AF, Dexter M, Micati A, Velasco TR, Machado HR, Martino AM, Huang A, Wheatley BM, Grant GA, Granata T, Freri E, Garbelli R, Koh S, Nordli DR, Campos AR, O'Neill B, Handler MH, Chapman KE, Wilfong AA, Curry DJ, Yaun A, Madsen JR, Smyth MD, Mercer D, Bingaman W, Harvey AS, Leventer RJ, Lockhart PJ, Gillies G, Pope K, Giller CA, Park YD, Rojiani AM, Sharma SJ, Jenkins P, Tung S, Huynh MN, Chirwa TW, Cepeda C, Levine MS, Chang JW, Owens GC, Vinters HV, Mathern GW.

Epilepsia. 2016 Jun;57(6):1005-7. doi: 10.1111/epi.13383. No abstract available.

19.

Outcome of hospital discharge on postoperative Day 1 following uncomplicated tethered spinal cord release.

Poonia S, Graber S, Corbett Wilkinson C, O'neill BR, Handler MH, Hankinson TC.

J Neurosurg Pediatr. 2016 Jun;17(6):651-6. doi: 10.3171/2015.10.PEDS15318. Epub 2016 Feb 5.

PMID:
26849810
20.

The Emergence of Zoonotic Onchocerca lupi Infection in the United States--A Case-Series.

Cantey PT, Weeks J, Edwards M, Rao S, Ostovar GA, Dehority W, Alzona M, Swoboda S, Christiaens B, Ballan W, Hartley J, Terranella A, Weatherhead J, Dunn JJ, Marx DP, Hicks MJ, Rauch RA, Smith C, Dishop MK, Handler MH, Dudley RW, Chundu K, Hobohm D, Feiz-Erfan I, Hakes J, Berry RS, Stepensaski S, Greenfield B, Shroeder L, Bishop H, de Almeida M, Mathison B, Eberhard M.

Clin Infect Dis. 2016 Mar 15;62(6):778-83. doi: 10.1093/cid/civ983. Epub 2015 Nov 26.

21.

Short-term mortality following surgical procedures for the diagnosis of pediatric brain tumors: outcome analysis in 5533 children from SEER, 2004-2011.

Hankinson TC, Dudley RW, Torok MR, Patibandla MR, Dorris K, Poonia S, Wilkinson CC, Bruny JL, Handler MH, Liu AK.

J Neurosurg Pediatr. 2016 Mar;17(3):289-97. doi: 10.3171/2015.7.PEDS15224. Epub 2015 Nov 20.

PMID:
26588456
22.

Routine perioperative ketorolac administration is not associated with hemorrhage in pediatric neurosurgery patients.

Richardson MD, Palmeri NO, Williams SA, Torok MR, O'Neill BR, Handler MH, Hankinson TC.

J Neurosurg Pediatr. 2016 Jan;17(1):107-15. doi: 10.3171/2015.4.PEDS14411. Epub 2015 Oct 9.

PMID:
26451718
23.

Atypical pediatric ganglioglioma is common and associated with a less favorable clinical course.

Patibandla MR, Ridder T, Dorris K, Torok MR, Liu AK, Handler MH, Stence NV, Fenton LZ, Hankinson TC.

J Neurosurg Pediatr. 2016 Jan;17(1):41-8. doi: 10.3171/2015.6.PEDS15215. Epub 2015 Oct 2.

PMID:
26431248
24.

Surgery for infants with catastrophic epilepsy: an analysis of complications and efficacy.

Kumar RM, Koh S, Knupp K, Handler MH, O'Neill BR.

Childs Nerv Syst. 2015 Sep;31(9):1479-91. doi: 10.1007/s00381-015-2759-6. Epub 2015 May 29.

PMID:
26022500
25.

Interleukin-6/STAT3 Pathway Signaling Drives an Inflammatory Phenotype in Group A Ependymoma.

Griesinger AM, Josephson RJ, Donson AM, Mulcahy Levy JM, Amani V, Birks DK, Hoffman LM, Furtek SL, Reigan P, Handler MH, Vibhakar R, Foreman NK.

Cancer Immunol Res. 2015 Oct;3(10):1165-74. doi: 10.1158/2326-6066.CIR-15-0061. Epub 2015 May 12.

26.

Incidence of seizures on continuous EEG monitoring following traumatic brain injury in children.

O'Neill BR, Handler MH, Tong S, Chapman KE.

J Neurosurg Pediatr. 2015 Aug;16(2):167-76. doi: 10.3171/2014.12.PEDS14263. Epub 2015 May 8.

PMID:
25955809
27.

A cervical spine mass caused by Onchocerca lupi.

Dudley RWR, Smith C, Dishop M, Mirsky D, Handler MH, Rao S.

Lancet. 2015 Oct 3;386(10001):1372. doi: 10.1016/S0140-6736(14)62255-8. Epub 2015 Apr 3. No abstract available.

PMID:
25843892
28.

Pediatric low-grade ganglioglioma: epidemiology, treatments, and outcome analysis on 348 children from the surveillance, epidemiology, and end results database.

Dudley RW, Torok MR, Gallegos DR, Mulcahy-Levy JM, Hoffman LM, Liu AK, Handler MH, Hankinson TC.

Neurosurgery. 2015 Mar;76(3):313-9; discussion 319; quiz 319-20. doi: 10.1227/NEU.0000000000000619.

29.

Pediatric choroid plexus tumors: epidemiology, treatments, and outcome analysis on 202 children from the SEER database.

Dudley RW, Torok MR, Gallegos D, Liu AK, Handler MH, Hankinson TC.

J Neurooncol. 2015 Jan;121(1):201-7. doi: 10.1007/s11060-014-1628-6. Epub 2014 Oct 9.

PMID:
25297498
30.

Autophagy inhibition improves chemosensitivity in BRAF(V600E) brain tumors.

Levy JM, Thompson JC, Griesinger AM, Amani V, Donson AM, Birks DK, Morgan MJ, Mirsky DM, Handler MH, Foreman NK, Thorburn A.

Cancer Discov. 2014 Jul;4(7):773-80. doi: 10.1158/2159-8290.CD-14-0049. Epub 2014 May 13.

31.

Patterns of care for craniopharyngioma: survey of members of the american association of neurological surgeons.

Hankinson TC, Palmeri NO, Williams SA, Torok MR, Serrano CA, Foreman NK, Handler MH, Liu AK.

Pediatr Neurosurg. 2013;49(3):131-6. doi: 10.1159/000357783. Epub 2014 Feb 21.

32.

Molecular sub-group-specific immunophenotypic changes are associated with outcome in recurrent posterior fossa ependymoma.

Hoffman LM, Donson AM, Nakachi I, Griesinger AM, Birks DK, Amani V, Hemenway MS, Liu AK, Wang M, Hankinson TC, Handler MH, Foreman NK.

Acta Neuropathol. 2014 May;127(5):731-45. doi: 10.1007/s00401-013-1212-8. Epub 2013 Nov 17.

33.

Pediatric brainstem gangliogliomas show BRAF(V600E) mutation in a high percentage of cases.

Donson AM, Kleinschmidt-DeMasters BK, Aisner DL, Bemis LT, Birks DK, Levy JM, Smith AA, Handler MH, Foreman NK, Rush SZ.

Brain Pathol. 2014 Mar;24(2):173-83. doi: 10.1111/bpa.12103. Epub 2013 Dec 23.

34.

Characterization of distinct immunophenotypes across pediatric brain tumor types.

Griesinger AM, Birks DK, Donson AM, Amani V, Hoffman LM, Waziri A, Wang M, Handler MH, Foreman NK.

J Immunol. 2013 Nov 1;191(9):4880-8. doi: 10.4049/jimmunol.1301966. Epub 2013 Sep 27.

35.

Fractionated stereotactic radiosurgery for recurrent ependymoma in children.

Hoffman LM, Plimpton SR, Foreman NK, Stence NV, Hankinson TC, Handler MH, Hemenway MS, Vibhakar R, Liu AK.

J Neurooncol. 2014 Jan;116(1):107-11.

36.

Minimally invasive technique for insertion of ventriculopleural shunt catheters.

Richardson MD, Handler MH.

J Neurosurg Pediatr. 2013 Nov;12(5):501-4. doi: 10.3171/2013.8.PEDS12517. Epub 2013 Sep 6.

PMID:
24011369
37.

Insulin-like growth factor 2 mRNA binding protein 3 expression is an independent prognostic factor in pediatric pilocytic and pilomyxoid astrocytoma.

Barton VN, Donson AM, Birks DK, Kleinschmidt-DeMasters BK, Handler MH, Foreman NK, Rush SZ.

J Neuropathol Exp Neurol. 2013 May;72(5):442-9. doi: 10.1097/NEN.0b013e31829023dd.

38.

Pediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes.

Birks DK, Donson AM, Patel PR, Sufit A, Algar EM, Dunham C, Kleinschmidt-DeMasters BK, Handler MH, Vibhakar R, Foreman NK.

Pediatr Blood Cancer. 2013 Jul;60(7):1095-102. doi: 10.1002/pbc.24481. Epub 2013 Feb 4.

39.

B7-H3, a potential therapeutic target, is expressed in diffuse intrinsic pontine glioma.

Zhou Z, Luther N, Ibrahim GM, Hawkins C, Vibhakar R, Handler MH, Souweidane MM.

J Neurooncol. 2013 Feb;111(3):257-64. doi: 10.1007/s11060-012-1021-2. Epub 2012 Dec 12.

40.

MicroRNA 218 acts as a tumor suppressor by targeting multiple cancer phenotype-associated genes in medulloblastoma.

Venkataraman S, Birks DK, Balakrishnan I, Alimova I, Harris PS, Patel PR, Handler MH, Dubuc A, Taylor MD, Foreman NK, Vibhakar R.

J Biol Chem. 2013 Jan 18;288(3):1918-28. doi: 10.1074/jbc.M112.396762. Epub 2012 Dec 4.

41.

Limited utility despite accuracy of the national SEER dataset for the study of craniopharyngioma.

Hankinson TC, Fields EC, Torok MR, Beaty BL, Handler MH, Foreman NK, O'neill BR, Liu AK.

J Neurooncol. 2012 Nov;110(2):271-8. doi: 10.1007/s11060-012-0966-5. Epub 2012 Aug 23.

PMID:
22915191
42.

Increased immune gene expression and immune cell infiltration in high-grade astrocytoma distinguish long-term from short-term survivors.

Donson AM, Birks DK, Schittone SA, Kleinschmidt-DeMasters BK, Sun DY, Hemenway MF, Handler MH, Waziri AE, Wang M, Foreman NK.

J Immunol. 2012 Aug 15;189(4):1920-7. doi: 10.4049/jimmunol.1103373. Epub 2012 Jul 16.

43.

Diffuse intrinsic pontine tumors: a study of primitive neuroectodermal tumors versus the more common diffuse intrinsic pontine gliomas.

Sufit A, Donson AM, Birks DK, Knipstein JA, Fenton LZ, Jedlicka P, Hankinson TC, Handler MH, Foreman NK.

J Neurosurg Pediatr. 2012 Aug;10(2):81-8. doi: 10.3171/2012.3.PEDS11316. Epub 2012 Jun 29.

44.

Clinical and molecular characteristics of congenital glioblastoma.

Macy ME, Birks DK, Barton VN, Chan MH, Donson AM, Kleinschmidt-Demasters BK, Bemis LT, Handler MH, Foreman NK.

Neuro Oncol. 2012 Jul;14(7):931-41. doi: 10.1093/neuonc/nos125. Epub 2012 Jun 18.

45.

Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells.

Harris PS, Venkataraman S, Alimova I, Birks DK, Donson AM, Knipstein J, Dubuc A, Taylor MD, Handler MH, Foreman NK, Vibhakar R.

BMC Cancer. 2012 Mar 5;12:80. doi: 10.1186/1471-2407-12-80.

46.

Comparison of outcomes following decompressive craniectomy in children with accidental and nonaccidental blunt cranial trauma.

Oluigbo CO, Wilkinson CC, Stence NV, Fenton LZ, McNatt SA, Handler MH.

J Neurosurg Pediatr. 2012 Feb;9(2):125-32. doi: 10.3171/2011.11.PEDS09449.

PMID:
22295915
47.

A proteomic analysis of pediatric seizure cases associated with astrocytic inclusions.

Visanji NP, Wong JC, Wang SX, Cappel B, Kleinschmidt-Demasters BK, Handler MH, Ochi A, Otsubo H, Rutka JT, Go C, Weiss S, Vinters HV, Hawkins CE, Desouza LV, Siu KW, Hazrati LN.

Epilepsia. 2012 Mar;53(3):e50-4. doi: 10.1111/j.1528-1167.2011.03369.x. Epub 2012 Jan 5.

48.

High expression of BMP pathway genes distinguishes a subset of atypical teratoid/rhabdoid tumors associated with shorter survival.

Birks DK, Donson AM, Patel PR, Dunham C, Muscat A, Algar EM, Ashley DM, Kleinschmidt-Demasters BK, Vibhakar R, Handler MH, Foreman NK.

Neuro Oncol. 2011 Dec;13(12):1296-307. doi: 10.1093/neuonc/nor140. Epub 2011 Sep 23.

49.

Interpretation of magnetic resonance images in diffuse intrinsic pontine glioma: a survey of pediatric neurosurgeons.

Hankinson TC, Campagna EJ, Foreman NK, Handler MH.

J Neurosurg Pediatr. 2011 Jul;8(1):97-102. doi: 10.3171/2011.4.PEDS1180.

PMID:
21721895
50.

Survey of MicroRNA expression in pediatric brain tumors.

Birks DK, Barton VN, Donson AM, Handler MH, Vibhakar R, Foreman NK.

Pediatr Blood Cancer. 2011 Feb;56(2):211-6. doi: 10.1002/pbc.22723. Epub 2010 Nov 3.

PMID:
21157891

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