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Items: 1 to 20 of 454

1.

Allogeneic hematopoietic stem cell transplantation in two brothers with DNA ligase IV deficiency: a case report and review of the literature.

Schober S, Schilbach K, Doering M, Cabanillas Stanchi KM, Holzer U, Kasteleiner P, Schittenhelm J, Schaefer JF, Mueller I, Lang P, Handgretinger R.

BMC Pediatr. 2019 Oct 11;19(1):346. doi: 10.1186/s12887-019-1724-z.

PMID:
31604460
2.

Hematopoietic stem cell transplantation for children with acute myeloid leukemia-results of the AML SCT-BFM 2007 trial.

Sauer MG, Lang PJ, Albert MH, Bader P, Creutzig U, Eyrich M, Greil J, Gruhn B, Holter W, Klingebiel T, Kremens B, von der Leyen H, Mauz-Körholz C, Meisel R, Mischke K, Müller I, Niemeyer CM, Peters C, Pohler C, Reinhardt D, Burkhardt B, Schlegel PG, Schulz AS, Schrum J, Sedlacek P, Strahm B, Woessmann W, Handgretinger R, Zimmermann M, Borkhardt A.

Leukemia. 2019 Oct 2. doi: 10.1038/s41375-019-0584-8. [Epub ahead of print]

PMID:
31578451
3.

Clinical applications of donor lymphocyte infusion from an HLA-haploidentical donor: consensus recommendations from the acute leukemia working party of the EBMT.

Dholaria B, Savani BN, Labopin M, Luznik L, Ruggeri A, Mielke S, Al Malki MM, Kongtim P, Fuchs E, Huang XJ, Locatelli F, Aversa F, Castagna L, Bacigalupo A, Martelli M, Blaise D, Ben Soussan P, Arnault Y, Handgretinger R, Roy DC, O'Donnell P, Bashey A, Solomon S, Romee R, Lewalle P, Gayoso J, Maschan M, Lazarus HM, Ballen K, Giebel S, Baron F, Ciceri F, Esteve J, Gorin NC, Spyridonidis A, Schmid C, Ciurea SO, Nagler A, Mohty M.

Haematologica. 2019 Sep 19. pii: haematol.2019.219790. doi: 10.3324/haematol.2019.219790. [Epub ahead of print]

4.

Comparison of procalcitonin and C-reactive protein as early diagnostic marker for the identification of transplant-related adverse events after allogeneic hematopoietic stem cell transplantation in pediatric patients.

Cabanillas Stanchi KM, Queudeville M, Malaval C, Feucht J, Schlegel P, Dobratz M, Seitz C, Müller I, Lang P, Handgretinger R, Döring M.

J Cancer Res Clin Oncol. 2019 Aug 24. doi: 10.1007/s00432-019-03008-9. [Epub ahead of print]

PMID:
31446489
5.

Ex vivo expansion of autologous, donor-derived NK-, γδT-, and cytokine induced killer (CIK) cells post haploidentical hematopoietic stem cell transplantation results in increased antitumor activity.

Schlegel P, Lang AM, Matela M, Horrer A, Schilling A, Jöchner A, Wiedenmann M, Seitz C, Döring M, Feuchtinger T, Heubach F, Rabsteyn A, Handgretinger R, Lang P.

Bone Marrow Transplant. 2019 Aug;54(Suppl 2):727-732. doi: 10.1038/s41409-019-0609-y.

PMID:
31431711
6.

ADCC can improve graft vs leukemia effect after T- and B-cell depleted haploidentical stem cell transplantation in pediatric B-lineage ALL.

Schlegel P, Jung G, Lang AM, Döring M, Schulte JH, Ebinger M, Holzer U, Heubach F, Seitz C, Lang B, Hundsdörfer P, Eggert A, Eichholz T, Kreyenberg H, Lang P, Handgretinger R.

Bone Marrow Transplant. 2019 Aug;54(Suppl 2):689-693. doi: 10.1038/s41409-019-0606-1.

PMID:
31431707
7.

Diagnostic value of whole-body MRI in Opsoclonus-myoclonus syndrome: a clinical case series (3 case reports).

Storz C, Bares R, Ebinger M, Handgretinger R, Tsiflikas I, Schäfer JF.

BMC Med Imaging. 2019 Aug 20;19(1):70. doi: 10.1186/s12880-019-0372-y.

8.

The German National Registry of Primary Immunodeficiencies (2012-2017).

El-Helou SM, Biegner AK, Bode S, Ehl SR, Heeg M, Maccari ME, Ritterbusch H, Speckmann C, Rusch S, Scheible R, Warnatz K, Atschekzei F, Beider R, Ernst D, Gerschmann S, Jablonka A, Mielke G, Schmidt RE, Schürmann G, Sogkas G, Baumann UH, Klemann C, Viemann D, von Bernuth H, Krüger R, Hanitsch LG, Scheibenbogen CM, Wittke K, Albert MH, Eichinger A, Hauck F, Klein C, Rack-Hoch A, Sollinger FM, Avila A, Borte M, Borte S, Fasshauer M, Hauenherm A, Kellner N, Müller AH, Ülzen A, Bader P, Bakhtiar S, Lee JY, Heß U, Schubert R, Wölke S, Zielen S, Ghosh S, Laws HJ, Neubert J, Oommen PT, Hönig M, Schulz A, Steinmann S, Schwarz K, Dückers G, Lamers B, Langemeyer V, Niehues T, Shai S, Graf D, Müglich C, Schmalzing MT, Schwaneck EC, Tony HP, Dirks J, Haase G, Liese JG, Morbach H, Foell D, Hellige A, Wittkowski H, Masjosthusmann K, Mohr M, Geberzahn L, Hedrich CM, Müller C, Rösen-Wolff A, Roesler J, Zimmermann A, Behrends U, Rieber N, Schauer U, Handgretinger R, Holzer U, Henes J, Kanz L, Boesecke C, Rockstroh JK, Schwarze-Zander C, Wasmuth JC, Dilloo D, Hülsmann B, Schönberger S, Schreiber S, Zeuner R, Ankermann T, von Bismarck P, Huppertz HI, Kaiser-Labusch P, Greil J, Jakoby D, Kulozik AE, Metzler M, Naumann-Bartsch N, Sobik B, Graf N, Heine S, Kobbe R, Lehmberg K, Müller I, Herrmann F, Horneff G, Klein A, Peitz J, Schmidt N, Bielack S, Groß-Wieltsch U, Classen CF, Klasen J, Deutz P, Kamitz D, Lassay L, Tenbrock K, Wagner N, Bernbeck B, Brummel B, Lara-Villacanas E, Münstermann E, Schneider DT, Tietsch N, Westkemper M, Weiß M, Kramm C, Kühnle I, Kullmann S, Girschick H, Specker C, Vinnemeier-Laubenthal E, Haenicke H, Schulz C, Schweigerer L, Müller TG, Stiefel M, Belohradsky BH, Soetedjo V, Kindle G, Grimbacher B.

Front Immunol. 2019 Jul 19;10:1272. doi: 10.3389/fimmu.2019.01272. eCollection 2019.

9.

LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis.

Morishima T, Krahl AC, Nasri M, Xu Y, Aghaallaei N, Findik B, Klimiankou M, Ritter M, Hartmann MD, Gloeckner CJ, Stefanczyk S, Lindner C, Oswald B, Bernhard R, Hähnel K, Hermanutz-Klein U, Ebinger M, Handgretinger R, Casadei N, Welte K, Andre M, Müller P, Bajoghli B, Skokowa J.

Blood. 2019 Oct 3;134(14):1159-1175. doi: 10.1182/blood.2019000095. Epub 2019 Jul 31.

PMID:
31366618
10.

Invariant NKT Cells From Donor Lymphocyte Infusions (DLI-iNKTs) Promote ex vivo Lysis of Leukemic Blasts in a CD1d-Dependent Manner.

Jahnke S, Schmid H, Secker KA, Einhaus J, Duerr-Stoerzer S, Keppeler H, Schober-Melms I, Baur R, Schumm M, Handgretinger R, Bethge W, Kanz L, Schneidawind C, Schneidawind D.

Front Immunol. 2019 Jul 9;10:1542. doi: 10.3389/fimmu.2019.01542. eCollection 2019.

11.

Low mutational load in pediatric medulloblastoma still translates into neoantigens as targets for specific T-cell immunotherapy.

Blaeschke F, Paul MC, Schuhmann MU, Rabsteyn A, Schroeder C, Casadei N, Matthes J, Mohr C, Lotfi R, Wagner B, Kaeuferle T, Feucht J, Willier S, Handgretinger R, StevanoviĆ S, Lang P, Feuchtinger T.

Cytotherapy. 2019 Sep;21(9):973-986. doi: 10.1016/j.jcyt.2019.06.009. Epub 2019 Jul 25.

PMID:
31351799
12.

Fast enzymatic synthesis of n.c.a. 6-[18 F]fluorodopamine (FDA) from n.c.a. 6-[18 F]FDOPA and the fate of 6-FDOPA and 6-FDA in neuroblastoma and Caki-1 cells after their uptake.

Kuçi Z, Ehrlichmann W, Sauer J, Handgretinger R, Bruchelt G, Reischl G.

J Labelled Comp Radiopharm. 2019 Jun 30;62(8):438-447. doi: 10.1002/jlcr.3752.

PMID:
31090094
13.

Therapeutic targeting of mutant p53 in pediatric acute lymphoblastic leukemia.

Demir S, Boldrin E, Sun Q, Hampp S, Tausch E, Eckert C, Ebinger M, Handgretinger R, Te Kronnie G, Wiesmüller L, Stilgenbauer S, Selivanova G, Debatin KM, Meyer LH.

Haematologica. 2019 May 9. pii: haematol.2018.199364. doi: 10.3324/haematol.2018.199364. [Epub ahead of print]

14.

Pediatric Langerhans cell histiocytosis: the impact of mutational profile on clinical progression and late sequelae.

Nann D, Schneckenburger P, Steinhilber J, Metzler G, Beschorner R, Schwarze CP, Lang P, Handgretinger R, Fend F, Ebinger M, Bonzheim I.

Ann Hematol. 2019 Jul;98(7):1617-1626. doi: 10.1007/s00277-019-03678-y. Epub 2019 Mar 28.

PMID:
30923995
15.

G-CSF administration prior to donor lymphocyte apheresis promotes anti-leukaemic effects in allogeneic HCT patients.

Schneidawind C, Jahnke S, Schober-Melms I, Schumm M, Handgretinger R, Faul C, Kanz L, Bethge W, Schneidawind D.

Br J Haematol. 2019 Jul;186(1):60-71. doi: 10.1111/bjh.15881. Epub 2019 Mar 27.

PMID:
30916396
16.

CRISPR/Cas9-modified hematopoietic stem cells-present and future perspectives for stem cell transplantation.

Daniel-Moreno A, Lamsfus-Calle A, Raju J, Antony JS, Handgretinger R, Mezger M.

Bone Marrow Transplant. 2019 Mar 22. doi: 10.1038/s41409-019-0510-8. [Epub ahead of print] Review.

PMID:
30903024
17.

The European Society for Blood and Marrow Transplantation (EBMT) consensus recommendations for donor selection in haploidentical hematopoietic cell transplantation.

Ciurea SO, Al Malki MM, Kongtim P, Fuchs EJ, Luznik L, Huang XJ, Ciceri F, Locatelli F, Aversa F, Castagna L, Bacigalupo A, Martelli M, Blaise D, Ben Soussan P, Arnault Y, Handgretinger R, Roy DC, O'Donnell PV, Bashey A, Solomon S, Romee R, Gayoso J, Lazarus HM, Ballen K, Savani BN, Mohty M, Nagler A.

Bone Marrow Transplant. 2019 Mar 4. doi: 10.1038/s41409-019-0499-z. [Epub ahead of print] Review.

PMID:
30833742
18.

Immunosuppressive Total Nodal Irradiation-Based Reconditioning Regimens After Graft Rejection or Graft Failure in Pediatric Patients Treated With Myeloablative Allogeneic Hematopoietic Cell Transplantation.

Wegener D, Lang P, Paulsen F, Weidner N, Zips D, Ebinger M, Holzer U, Döring M, Basu O, Gruhn B, Wittig A, Teltschik HM, Handgretinger R, Heinzelmann F.

Int J Radiat Oncol Biol Phys. 2019 May 1;104(1):137-143. doi: 10.1016/j.ijrobp.2018.12.031. Epub 2018 Dec 26.

PMID:
30593907
19.

Gene correction of HBB mutations in CD34+ hematopoietic stem cells using Cas9 mRNA and ssODN donors.

Antony JS, Latifi N, Haque AKMA, Lamsfus-Calle A, Daniel-Moreno A, Graeter S, Baskaran P, Weinmann P, Mezger M, Handgretinger R, Kormann MSD.

Mol Cell Pediatr. 2018 Nov 14;5(1):9. doi: 10.1186/s40348-018-0086-1.

20.

Chemically modified hCFTR mRNAs recuperate lung function in a mouse model of cystic fibrosis.

Haque AKMA, Dewerth A, Antony JS, Riethmüller J, Schweizer GR, Weinmann P, Latifi N, Yasar H, Pedemonte N, Sondo E, Weidensee B, Ralhan A, Laval J, Schlegel P, Seitz C, Loretz B, Lehr CM, Handgretinger R, Kormann MSD.

Sci Rep. 2018 Nov 13;8(1):16776. doi: 10.1038/s41598-018-34960-0.

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