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Year Number of Results
1984 2
1995 1
1996 1
1997 2
1998 5
1999 11
2000 15
2001 8
2002 21
2003 18
2004 18
2005 18
2006 15
2007 14
2008 18
2009 15
2010 26
2011 32
2012 20
2013 25
2014 27
2015 24
2016 20
2017 41
2018 35
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655 results

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Page 1
HAND2-AS1: A functional cancer-related long non-coding RNA.
Gu X, Zheng Q, Chu Q, Zhu H. Gu X, et al. Biomed Pharmacother. 2021 May;137:111317. doi: 10.1016/j.biopha.2021.111317. Epub 2021 Feb 5. Biomed Pharmacother. 2021. PMID: 33556872 Free article. Review.
The aberrant expression of HAND2-AS1 was strongly linked to tumor progression and prognosis. ...This review summarizes data on the expression profile, functions, underlying mechanism, and clinical value of HAND2-AS1 in cancer. The expression profile of HAND2- …
The aberrant expression of HAND2-AS1 was strongly linked to tumor progression and prognosis. ...This review summarizes data on the ex …
A review on the role of HAND2-AS1 in cancer.
Ghafouri-Fard S, Hussen BM, Abdullah SR, Dadyar M, Taheri M, Kiani A. Ghafouri-Fard S, et al. Clin Exp Med. 2023 Nov;23(7):3179-3188. doi: 10.1007/s10238-023-01092-3. Epub 2023 May 19. Clin Exp Med. 2023. PMID: 37204522 Free PMC article. Review.
HAND2 antisense RNA 1 (HAND2-AS1) is a newly recognized lncRNA encoded by a gene on 4q34.1. ...Moreover, HAND2-AS1 has been shown to regulate expression of several targets with possible roles in the carcinogenesis through serving as a sponge for miRNAs. ...
HAND2 antisense RNA 1 (HAND2-AS1) is a newly recognized lncRNA encoded by a gene on 4q34.1. ...Moreover, HAND2-AS1 has …
Role of HAND2-AS1 in human tumors.
Da CM, Cheng ZY, Gong CY, Nan W, Zhou KS, Zhao GH, Zhang HH. Da CM, et al. Clin Chim Acta. 2020 Dec;511:189-197. doi: 10.1016/j.cca.2020.10.020. Epub 2020 Oct 21. Clin Chim Acta. 2020. PMID: 33096034 Review.
Therefore, HAND2-AS1 may be a promising tumor biomarker and therapeutic target. Here, we review the biological functions, mechanisms, and potential clinical significance of HAND2-AS1 in numerous human tumors....
Therefore, HAND2-AS1 may be a promising tumor biomarker and therapeutic target. Here, we review the biological functions, mechanisms, …
Long noncoding RNA HAND2-AS1: A crucial regulator of malignancy.
Huang Z, Wang Z, Xia H, Ge Z, Yu L, Li J, Bao H, Liang Z, Cui Y, Xu Y. Huang Z, et al. Clin Chim Acta. 2023 Jan 15;539:162-169. doi: 10.1016/j.cca.2022.12.010. Epub 2022 Dec 15. Clin Chim Acta. 2023. PMID: 36528049 Review.
Additionally, aberrantly expressed HAND2-AS1 was closely related to the clinical pathological characteristics of cancer patients and serve as a promising tumor diagnostic and prognostic biomarker. This article aims to review the roles of HAND2-AS1 in tumorigenesis a …
Additionally, aberrantly expressed HAND2-AS1 was closely related to the clinical pathological characteristics of cancer patients and …
HAND2 Assists MYCN Enhancer Invasion to Regulate a Noradrenergic Neuroblastoma Phenotype.
Xu M, Sun M, Zhang X, Nguyen R, Lei H, Shern JF, Thiele CJ, Liu Z. Xu M, et al. Cancer Res. 2023 Mar 2;83(5):686-699. doi: 10.1158/0008-5472.CAN-22-2042. Cancer Res. 2023. PMID: 36598365 Free PMC article.
Moreover, HAND2 cooperated with MYCN to compete with nucleosomes to regulate global gene transcription. ...SIGNIFICANCE: HAND2 and MYCN compete with nucleosomes to regulate global gene transcription and to drive a malignant neuroblastoma phenotype....
Moreover, HAND2 cooperated with MYCN to compete with nucleosomes to regulate global gene transcription. ...SIGNIFICANCE: HAND2 …
The Hand2 gene dosage effect in developmental defects and human congenital disorders.
Tamura M, Amano T, Shiroishi T. Tamura M, et al. Curr Top Dev Biol. 2014;110:129-52. doi: 10.1016/B978-0-12-405943-6.00003-8. Curr Top Dev Biol. 2014. PMID: 25248475 Review.
They form heterodimers with Twist1 via their HLH domain. Disruption of the expression balance between Hand2 and Twist1 causes limb malformation, indicating that the expression level of Hand2 relative to Twist1 is essential for limb development. ...In this review, we …
They form heterodimers with Twist1 via their HLH domain. Disruption of the expression balance between Hand2 and Twist1 causes limb ma …
HAND2-AS1 targeting miR-1208/SIRT1 axis alleviates foam cell formation in atherosclerosis.
Ma L, He S, Li H, Zhang S, Yin Y. Ma L, et al. Int J Cardiol. 2022 Jan 1;346:53-61. doi: 10.1016/j.ijcard.2021.11.019. Epub 2021 Nov 13. Int J Cardiol. 2022. PMID: 34780888
HAND2-AS1 endogenously sponged miR-128 and suppressed its activity via sequence complementation. ...Besides, HAND2-AS1 may be used to be the possible anti-AS therapeutic target....
HAND2-AS1 endogenously sponged miR-128 and suppressed its activity via sequence complementation. ...Besides, HAND2-AS1 may be …
HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling.
Giroud M, Tsokanos FF, Caratti G, Kotschi S, Khani S, Jouffe C, Vogl ES, Irmler M, Glantschnig C, Gil-Lozano M, Hass D, Khan AA, Garcia MR, Mattijssen F, Maida A, Tews D, Fischer-Posovszky P, Feuchtinger A, Virtanen KA, Beckers J, Wabitsch M, Uhlenhaut H, Blüher M, Tuckermann J, Scheideler M, Bartelt A, Herzig S. Giroud M, et al. Diabetologia. 2021 Aug;64(8):1850-1865. doi: 10.1007/s00125-021-05470-y. Epub 2021 May 20. Diabetologia. 2021. PMID: 34014371 Free PMC article.
A combinatorial RNA sequencing (RNAseq) and ChIP qPCR approach was used to identify target genes regulated by HAND2. In vivo, we created a conditional adipocyte Hand2 deletion mouse model using Cre under control of the Adipoq promoter (Hand2(AdipoqCre)) and p …
A combinatorial RNA sequencing (RNAseq) and ChIP qPCR approach was used to identify target genes regulated by HAND2. In vivo, we crea …
Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma.
Prummel KD, Crowell HL, Nieuwenhuize S, Brombacher EC, Daetwyler S, Soneson C, Kresoja-Rakic J, Kocere A, Ronner M, Ernst A, Labbaf Z, Clouthier DE, Firulli AB, Sánchez-Iranzo H, Naganathan SR, O'Rourke R, Raz E, Mercader N, Burger A, Felley-Bosco E, Huisken J, Robinson MD, Mosimann C. Prummel KD, et al. Nat Commun. 2022 Mar 30;13(1):1677. doi: 10.1038/s41467-022-29311-7. Nat Commun. 2022. PMID: 35354817 Free PMC article.
Single-cell transcriptomics uncovers a post-gastrulation gene expression signature centered on hand2 in distinct LPM progenitor cells. We map mesothelial progenitors to lateral-most, hand2-expressing LPM and confirm conservation in mouse. ...In mouse and human mesot …
Single-cell transcriptomics uncovers a post-gastrulation gene expression signature centered on hand2 in distinct LPM progenitor cells …
655 results