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Items: 1 to 50 of 630

1.

Hyaluronic acid-based nanogels improve in vivo compatibility of the anti-biofilm peptide DJK-5.

Kłodzińska SN, Pletzer D, Rahanjam N, Rades T, Hancock REW, Nielsen HM.

Nanomedicine. 2019 Jun 4:102022. doi: 10.1016/j.nano.2019.102022. [Epub ahead of print]

PMID:
31170510
2.

Short Cationic Peptide Derived from Archaea with Dual Antibacterial Properties and Anti-Infective Potential.

Cândido ES, Cardoso MH, Chan LY, Torres MDT, Oshiro KGN, Porto WF, Ribeiro SM, Haney EF, Hancock REW, Lu TK, de la Fuente-Nunez C, Craik DJ, Franco OL.

ACS Infect Dis. 2019 May 1. doi: 10.1021/acsinfecdis.9b00073. [Epub ahead of print]

PMID:
31016969
3.

Identification of novel Adenosine Deaminase 2 gene variants and varied clinical phenotype in pediatric vasculitis.

Gibson KM, Morishita KA, Dancey P, Moorehead P, Drögemöller B, Han X, Graham J, Hancock RE, Foell D, Benseler S, Luqmani R, Yeung RSM, Shenoi S, Bohm M, Rosenberg AM, Ross CJ, Cabral DA, Brown KL; PedVas investigators network.

Arthritis Rheumatol. 2019 Apr 22. doi: 10.1002/art.40913. [Epub ahead of print]

PMID:
31008556
4.

NetworkAnalyst 3.0: a visual analytics platform for comprehensive gene expression profiling and meta-analysis.

Zhou G, Soufan O, Ewald J, Hancock REW, Basu N, Xia J.

Nucleic Acids Res. 2019 Apr 1. pii: gkz240. doi: 10.1093/nar/gkz240. [Epub ahead of print]

PMID:
30931480
5.

Dismantling the bacterial virulence program.

Alford MA, Pletzer D, Hancock REW.

Microb Biotechnol. 2019 May;12(3):409-413. doi: 10.1111/1751-7915.13388. Epub 2019 Mar 12.

6.

Dynamic molecular changes during the first week of human life follow a robust developmental trajectory.

Lee AH, Shannon CP, Amenyogbe N, Bennike TB, Diray-Arce J, Idoko OT, Gill EE, Ben-Othman R, Pomat WS, van Haren SD, Cao KL, Cox M, Darboe A, Falsafi R, Ferrari D, Harbeson DJ, He D, Bing C, Hinshaw SJ, Ndure J, Njie-Jobe J, Pettengill MA, Richmond PC, Ford R, Saleu G, Masiria G, Matlam JP, Kirarock W, Roberts E, Malek M, Sanchez-Schmitz G, Singh A, Angelidou A, Smolen KK; EPIC Consortium, Brinkman RR, Ozonoff A, Hancock REW, van den Biggelaar AHJ, Steen H, Tebbutt SJ, Kampmann B, Levy O, Kollmann TR.

Nat Commun. 2019 Mar 12;10(1):1092. doi: 10.1038/s41467-019-08794-x.

7.

Reassessing the Host Defense Peptide Landscape.

Haney EF, Straus SK, Hancock REW.

Front Chem. 2019 Feb 4;7:43. doi: 10.3389/fchem.2019.00043. eCollection 2019. Review.

8.

A lipidic delivery system of a triple vaccine adjuvant enhances mucosal immunity following nasal administration in mice.

Wasan EK, Syeda J, Strom S, Cawthray J, Hancock RE, Wasan KM, Gerdts V.

Vaccine. 2019 Mar 7;37(11):1503-1515. doi: 10.1016/j.vaccine.2019.01.058. Epub 2019 Feb 7.

PMID:
30739796
9.

Aurein-Derived Antimicrobial Peptides Formulated with Pegylated Phospholipid Micelles to Target Methicillin-Resistant Staphylococcus aureus Skin Infections.

Kumar P, Pletzer D, Haney EF, Rahanjam N, Cheng JTJ, Yue M, Aljehani W, Hancock REW, Kizhakkedathu JN, Straus SK.

ACS Infect Dis. 2019 Mar 8;5(3):443-453. doi: 10.1021/acsinfecdis.8b00319. Epub 2019 Jan 2.

PMID:
30565465
10.

Bone Environment Influences Irreversible Adhesion of a Methicillin-Susceptible Staphylococcus aureus Strain.

Reffuveille F, Josse J, Velard F, Lamret F, Varin-Simon J, Dubus M, Haney EF, Hancock REW, Mongaret C, Gangloff SC.

Front Microbiol. 2018 Nov 27;9:2865. doi: 10.3389/fmicb.2018.02865. eCollection 2018.

11.

S100A12 Serum Levels and PMN Counts Are Elevated in Childhood Systemic Vasculitides Especially Involving Proteinase 3 Specific Anti-neutrophil Cytoplasmic Antibodies.

Brown KL, Lubieniecka JM, Armaroli G, Kessel K, Gibson KM, Graham J, Liu D, Hancock REW, Ross CJ, Benseler SM, Luqmani RA, Cabral DA, Foell D, Kessel C.

Front Pediatr. 2018 Nov 23;6:341. doi: 10.3389/fped.2018.00341. eCollection 2018.

12.

Is synergy the key to treating high-density infections?

Pletzer D, Hancock RE.

Future Microbiol. 2018 Nov;13:1629-1632. doi: 10.2217/fmb-2018-0216. Epub 2018 Nov 14. No abstract available.

PMID:
30426796
13.

Characterization of Host Responses during Pseudomonas aeruginosa Acute Infection in the Lungs and Blood and after Treatment with the Synthetic Immunomodulatory Peptide IDR-1002.

Wuerth K, Lee AHY, Falsafi R, Gill EE, Hancock REW.

Infect Immun. 2018 Dec 19;87(1). pii: e00661-18. doi: 10.1128/IAI.00661-18. Print 2019 Jan.

14.

Antimicrobial Effect of Peptide DJK-5 Used Alone or Mixed with EDTA on Mono- and Multispecies Biofilms in Dentin Canals.

Wang D, Shen Y, Hancock REW, Ma J, Haapasalo M.

J Endod. 2018 Nov;44(11):1709-1713. doi: 10.1016/j.joen.2018.07.018. Epub 2018 Sep 19.

PMID:
30243660
15.

Surfing Motility: a Conserved yet Diverse Adaptation among Motile Bacteria.

Sun E, Liu S, Hancock REW.

J Bacteriol. 2018 Nov 6;200(23). pii: e00394-18. doi: 10.1128/JB.00394-18. Print 2018 Dec 1.

16.

Interleukin-22 promotes phagolysosomal fusion to induce protection against Salmonella enterica Typhimurium in human epithelial cells.

Forbester JL, Lees EA, Goulding D, Forrest S, Yeung A, Speak A, Clare S, Coomber EL, Mukhopadhyay S, Kraiczy J, Schreiber F, Lawley TD, Hancock REW, Uhlig HH, Zilbauer M, Powrie F, Dougan G.

Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):10118-10123. doi: 10.1073/pnas.1811866115. Epub 2018 Sep 14.

17.

Design and Assessment of Anti-Biofilm Peptides: Steps Toward Clinical Application.

Dostert M, Belanger CR, Hancock REW.

J Innate Immun. 2019;11(3):193-204. doi: 10.1159/000491497. Epub 2018 Aug 22. Review.

18.

Broad-Spectrum Adaptive Antibiotic Resistance Associated with Pseudomonas aeruginosa Mucin-Dependent Surfing Motility.

Sun E, Gill EE, Falsafi R, Yeung A, Liu S, Hancock REW.

Antimicrob Agents Chemother. 2018 Aug 27;62(9). pii: e00848-18. doi: 10.1128/AAC.00848-18. Print 2018 Sep.

19.

Liposomal Therapy Attenuates Dermonecrosis Induced by Community-Associated Methicillin-Resistant Staphylococcus aureus by Targeting α-Type Phenol-Soluble Modulins and α-Hemolysin.

Wolfmeier H, Mansour SC, Liu LT, Pletzer D, Draeger A, Babiychuk EB, Hancock REW.

EBioMedicine. 2018 Jul;33:211-217. doi: 10.1016/j.ebiom.2018.06.016. Epub 2018 Jun 20.

20.

Synergy between conventional antibiotics and anti-biofilm peptides in a murine, sub-cutaneous abscess model caused by recalcitrant ESKAPE pathogens.

Pletzer D, Mansour SC, Hancock REW.

PLoS Pathog. 2018 Jun 21;14(6):e1007084. doi: 10.1371/journal.ppat.1007084. eCollection 2018 Jun.

21.

Critical Assessment of Methods to Quantify Biofilm Growth and Evaluate Antibiofilm Activity of Host Defence Peptides.

Haney EF, Trimble MJ, Cheng JT, Vallé Q, Hancock REW.

Biomolecules. 2018 May 21;8(2). pii: E29. doi: 10.3390/biom8020029.

22.

Retinoic acid elicits a coordinated expression of gut homing markers on T lymphocytes of Zambian men receiving oral Vivotif, but not Rotarix, Dukoral or OPVERO vaccines.

Mwanza-Lisulo M, Chomba MS, Chama M, Besa EC, Funjika E, Zyambo K, Banda R, Imikendu M, Sianongo S, Hancock REW, Lee A, Chilengi R, Stagg AJ, Namangala B, Kelly PM.

Vaccine. 2018 Jun 27;36(28):4134-4141. doi: 10.1016/j.vaccine.2018.04.083. Epub 2018 May 22.

23.

Development of Molecularly Imprinted Polymers To Block Quorum Sensing and Inhibit Bacterial Biofilm Formation.

Ma L, Feng S, Fuente-Núñez C, Hancock REW, Lu X.

ACS Appl Mater Interfaces. 2018 Jun 6;10(22):18450-18457. doi: 10.1021/acsami.8b01584. Epub 2018 May 25.

PMID:
29767954
24.

Helicobacter pylori Biofilm Formation Is Differentially Affected by Common Culture Conditions, and Proteins Play a Central Role in the Biofilm Matrix.

Windham IH, Servetas SL, Whitmire JM, Pletzer D, Hancock REW, Merrell DS.

Appl Environ Microbiol. 2018 Jul 2;84(14). pii: e00391-18. doi: 10.1128/AEM.00391-18. Print 2018 Jul 15.

25.

MetaBridge: enabling network-based integrative analysis via direct protein interactors of metabolites.

Hinshaw SJ, Lee AHY, Gill EE, Hancock REW.

Bioinformatics. 2018 Sep 15;34(18):3225-3227. doi: 10.1093/bioinformatics/bty331.

PMID:
29688253
26.

In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design.

Porto WF, Irazazabal L, Alves ESF, Ribeiro SM, Matos CO, Pires ÁS, Fensterseifer ICM, Miranda VJ, Haney EF, Humblot V, Torres MDT, Hancock REW, Liao LM, Ladram A, Lu TK, de la Fuente-Nunez C, Franco OL.

Nat Commun. 2018 Apr 16;9(1):1490. doi: 10.1038/s41467-018-03746-3.

27.

High-throughput detection of RNA processing in bacteria.

Gill EE, Chan LS, Winsor GL, Dobson N, Lo R, Ho Sui SJ, Dhillon BK, Taylor PK, Shrestha R, Spencer C, Hancock REW, Unrau PJ, Brinkman FSL.

BMC Genomics. 2018 Mar 27;19(1):223. doi: 10.1186/s12864-018-4538-8.

28.

Computer-aided Discovery of Peptides that Specifically Attack Bacterial Biofilms.

Haney EF, Brito-Sánchez Y, Trimble MJ, Mansour SC, Cherkasov A, Hancock REW.

Sci Rep. 2018 Jan 30;8(1):1871. doi: 10.1038/s41598-018-19669-4.

29.

Induction by innate defence regulator peptide 1018 of pro-angiogenic molecules and endothelial cell migration in a high glucose environment.

Marin-Luevano P, Trujillo V, Rodriguez-Carlos A, González-Curiel I, Enciso-Moreno JA, Hancock REW, Rivas-Santiago B.

Peptides. 2018 Mar;101:135-144. doi: 10.1016/j.peptides.2018.01.010. Epub 2018 Jan 17.

PMID:
29353019
30.

New Perspectives in Biofilm Eradication.

Wolfmeier H, Pletzer D, Mansour SC, Hancock REW.

ACS Infect Dis. 2018 Feb 9;4(2):93-106. doi: 10.1021/acsinfecdis.7b00170. Epub 2017 Dec 27. Review.

PMID:
29280609
31.

Synthetic host defense peptide IDR-1002 reduces inflammation in Pseudomonas aeruginosa lung infection.

Wuerth KC, Falsafi R, Hancock REW.

PLoS One. 2017 Nov 6;12(11):e0187565. doi: 10.1371/journal.pone.0187565. eCollection 2017.

32.

Synthetic Peptides to Target Stringent Response-Controlled Virulence in a Pseudomonas aeruginosa Murine Cutaneous Infection Model.

Pletzer D, Wolfmeier H, Bains M, Hancock REW.

Front Microbiol. 2017 Sep 27;8:1867. doi: 10.3389/fmicb.2017.01867. eCollection 2017.

33.

Mechanisms of the Innate Defense Regulator Peptide-1002 Anti-Inflammatory Activity in a Sterile Inflammation Mouse Model.

Wu BC, Lee AH, Hancock REW.

J Immunol. 2017 Nov 15;199(10):3592-3603. doi: 10.4049/jimmunol.1700985. Epub 2017 Oct 9.

34.

Antibiofilm Effect of D-enantiomeric Peptide Alone and Combined with EDTA In Vitro.

Wang D, Shen Y, Ma J, Hancock REW, Haapasalo M.

J Endod. 2017 Nov;43(11):1862-1867. doi: 10.1016/j.joen.2017.06.037. Epub 2017 Sep 23.

PMID:
28951034
35.

Aggregation and Its Influence on the Immunomodulatory Activity of Synthetic Innate Defense Regulator Peptides.

Haney EF, Wu BC, Lee K, Hilchie AL, Hancock REW.

Cell Chem Biol. 2017 Aug 17;24(8):969-980.e4. doi: 10.1016/j.chembiol.2017.07.010. Epub 2017 Aug 10.

36.

Sensing Mg2+ contributes to the resistance of Pseudomonas aeruginosa to complement-mediated opsonophagocytosis.

Qadi M, Izquierdo-Rabassa S, Mateu Borrás M, Doménech-Sánchez A, Juan C, Goldberg JB, Hancock REW, Albertí S.

Environ Microbiol. 2017 Oct;19(10):4278-4286. doi: 10.1111/1462-2920.13889. Epub 2017 Sep 15.

PMID:
28805355
37.

A novel small RNA is important for biofilm formation and pathogenicity in Pseudomonas aeruginosa.

Taylor PK, Van Kessel ATM, Colavita A, Hancock REW, Mah TF.

PLoS One. 2017 Aug 3;12(8):e0182582. doi: 10.1371/journal.pone.0182582. eCollection 2017.

38.

Ciprofloxacin-nitroxide hybrids with potential for biofilm control.

Verderosa AD, de la Fuente-Núñez C, Mansour SC, Cao J, Lu TK, Hancock REW, Fairfull-Smith KE.

Eur J Med Chem. 2017 Sep 29;138:590-601. doi: 10.1016/j.ejmech.2017.06.058. Epub 2017 Jun 28.

PMID:
28709125
39.

An Immunomodulatory Peptide Confers Protection in an Experimental Candidemia Murine Model.

Freitas CG, Lima SMF, Freire MS, Cantuária APC, Júnior NGO, Santos TS, Folha JS, Ribeiro SM, Dias SC, Rezende TMB, Albuquerque P, Nicola AM, de la Fuente-Núñez C, Hancock REW, Franco OL, Felipe MSS.

Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e02518-16. doi: 10.1128/AAC.02518-16. Print 2017 Aug.

40.

Return to Play After Shoulder Instability Surgery in National Collegiate Athletic Association Division I Intercollegiate Football Athletes.

Robins RJ, Daruwalla JH, Gamradt SC, McCarty EC, Dragoo JL, Hancock RE, Guy JA, Cotsonis GA, Xerogeanes JW; ASP Collaborative Group, Tuman JM, Tibone JE, Javernick MA, Yochem EM, Boden SA, Pilato A, Miley JH, Greis PE.

Am J Sports Med. 2017 Aug;45(10):2329-2335. doi: 10.1177/0363546517705635. Epub 2017 May 30.

PMID:
28557527
41.

Exploiting induced pluripotent stem cell-derived macrophages to unravel host factors influencing Chlamydia trachomatis pathogenesis.

Yeung ATY, Hale C, Lee AH, Gill EE, Bushell W, Parry-Smith D, Goulding D, Pickard D, Roumeliotis T, Choudhary J, Thomson N, Skarnes WC, Dougan G, Hancock REW.

Nat Commun. 2017 Apr 25;8:15013. doi: 10.1038/ncomms15013.

42.

Exosomes, your body's answer to immune health.

Baquir B, Hancock RE.

Ann Transl Med. 2017 Feb;5(4):81. doi: 10.21037/atm.2017.01.50. No abstract available.

43.

An alternative approach to treating antibiotic-resistant infections.

Trimble MJ, Hancock RE.

Future Microbiol. 2017 Mar;12:201-204. doi: 10.2217/fmb-2016-0222. Epub 2017 Feb 15. No abstract available.

PMID:
28262044
44.

Antimicrobial efficacy against Pseudomonas aeruginosa biofilm formation in a three-dimensional lung epithelial model and the influence of fetal bovine serum.

Crabbé A, Liu Y, Matthijs N, Rigole P, De La Fuente-Nùñez C, Davis R, Ledesma MA, Sarker S, Van Houdt R, Hancock RE, Coenye T, Nickerson CA.

Sci Rep. 2017 Mar 3;7:43321. doi: 10.1038/srep43321.

45.

New Mouse Model for Chronic Infections by Gram-Negative Bacteria Enabling the Study of Anti-Infective Efficacy and Host-Microbe Interactions.

Pletzer D, Mansour SC, Wuerth K, Rahanjam N, Hancock RE.

MBio. 2017 Feb 28;8(1). pii: e00140-17. doi: 10.1128/mBio.00140-17.

46.

Anticancer activities of bovine and human lactoferricin-derived peptides.

Arias M, Hilchie AL, Haney EF, Bolscher JG, Hyndman ME, Hancock RE, Vogel HJ.

Biochem Cell Biol. 2017 Feb;95(1):91-98. doi: 10.1139/bcb-2016-0175. Epub 2016 Nov 3.

PMID:
28165293
47.

High-Performance Liquid Chromatography and Mass Spectrometry-Based Design of Proteolytically Stable Antimicrobial Peptides.

Bagheri M, Hancock RE.

Methods Mol Biol. 2017;1548:61-71. doi: 10.1007/978-1-4939-6737-7_5.

PMID:
28013497
48.

Antimicrobial Peptides: An Introduction.

Haney EF, Mansour SC, Hancock RE.

Methods Mol Biol. 2017;1548:3-22. doi: 10.1007/978-1-4939-6737-7_1. Review.

PMID:
28013493
49.
50.

Anti-adhesive antimicrobial peptide coating prevents catheter associated infection in a mouse urinary infection model.

Yu K, Lo JC, Yan M, Yang X, Brooks DE, Hancock RE, Lange D, Kizhakkedathu JN.

Biomaterials. 2017 Feb;116:69-81. doi: 10.1016/j.biomaterials.2016.11.047. Epub 2016 Nov 24.

PMID:
27914268

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