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Items: 41

1.

Development of combination therapies to maximize the impact of KRAS-G12C inhibitors in lung cancer.

Molina-Arcas M, Moore C, Rana S, van Maldegem F, Mugarza E, Romero-Clavijo P, Herbert E, Horswell S, Li LS, Janes MR, Hancock DC, Downward J.

Sci Transl Med. 2019 Sep 18;11(510). pii: eaaw7999. doi: 10.1126/scitranslmed.aaw7999.

PMID:
31534020
2.

RAC1P29S Induces a Mesenchymal Phenotypic Switch via Serum Response Factor to Promote Melanoma Development and Therapy Resistance.

Lionarons DA, Hancock DC, Rana S, East P, Moore C, Murillo MM, Carvalho J, Spencer-Dene B, Herbert E, Stamp G, Damry D, Calado DP, Rosewell I, Fritsch R, Neubig RR, Molina-Arcas M, Downward J.

Cancer Cell. 2019 Jul 8;36(1):68-83.e9. doi: 10.1016/j.ccell.2019.05.015. Epub 2019 Jun 27.

3.

AKT signalling selectively regulates PINK1 mitophagy in SHSY5Y cells and human iPSC-derived neurons.

Soutar MPM, Kempthorne L, Miyakawa S, Annuario E, Melandri D, Harley J, O'Sullivan GA, Wray S, Hancock DC, Cookson MR, Downward J, Carlton M, Plun-Favreau H.

Sci Rep. 2018 Jun 11;8(1):8855. doi: 10.1038/s41598-018-26949-6.

4.

Expectations and experiences of nursing students in clinical courses: A descriptive study.

Cowen KJ, Hubbard LJ, Hancock DC.

Nurse Educ Today. 2018 Aug;67:15-20. doi: 10.1016/j.nedt.2018.04.024. Epub 2018 Apr 25.

PMID:
29727825
5.

Concerns of nursing students beginning clinical courses: A descriptive study.

Cowen KJ, Hubbard LJ, Hancock DC.

Nurse Educ Today. 2016 Aug;43:64-8. doi: 10.1016/j.nedt.2016.05.001. Epub 2016 May 12.

PMID:
27286947
6.

ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1.

Wang Y, Bu F, Royer C, Serres S, Larkin JR, Soto MS, Sibson NR, Salter V, Fritzsche F, Turnquist C, Koch S, Zak J, Zhong S, Wu G, Liang A, Olofsen PA, Moch H, Hancock DC, Downward J, Goldin RD, Zhao J, Tong X, Guo Y, Lu X.

Nat Cell Biol. 2014 Nov;16(11):1092-104. doi: 10.1038/ncb3050. Epub 2014 Oct 26.

PMID:
25344754
7.

Coordinate direct input of both KRAS and IGF1 receptor to activation of PI3 kinase in KRAS-mutant lung cancer.

Molina-Arcas M, Hancock DC, Sheridan C, Kumar MS, Downward J.

Cancer Discov. 2013 May;3(5):548-63. doi: 10.1158/2159-8290.CD-12-0446. Epub 2013 Mar 1.

8.

Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies.

Steckel M, Molina-Arcas M, Weigelt B, Marani M, Warne PH, Kuznetsov H, Kelly G, Saunders B, Howell M, Downward J, Hancock DC.

Cell Res. 2012 Aug;22(8):1227-45. doi: 10.1038/cr.2012.82. Epub 2012 May 22.

9.

The GATA2 transcriptional network is requisite for RAS oncogene-driven non-small cell lung cancer.

Kumar MS, Hancock DC, Molina-Arcas M, Steckel M, East P, Diefenbacher M, Armenteros-Monterroso E, Lassailly F, Matthews N, Nye E, Stamp G, Behrens A, Downward J.

Cell. 2012 Apr 27;149(3):642-55. doi: 10.1016/j.cell.2012.02.059.

10.

Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells.

Nicke B, Bastien J, Khanna SJ, Warne PH, Cowling V, Cook SJ, Peters G, Delpuech O, Schulze A, Berns K, Mullenders J, Beijersbergen RL, Bernards R, Ganesan TS, Downward J, Hancock DC.

Mol Cell. 2005 Dec 9;20(5):673-85.

11.

Production of polyclonal antibodies in rabbits.

Hancock DC, O'Reilly NJ.

Methods Mol Biol. 2005;295:27-40.

PMID:
15596886
12.

Synthetic peptides as antigens for antibody production.

Hancock DC, O'Reilly NJ.

Methods Mol Biol. 2005;295:13-26.

PMID:
15596885
13.

Suppression of c-Myc-induced apoptosis by the Epstein-Barr virus gene product BHRF1.

Fanidi A, Hancock DC, Littlewood TD.

J Virol. 1998 Oct;72(10):8392-5.

14.

Synthesis of peptides for use as immunogens.

Hancock DC, O'Reilly NJ, Evan GI.

Methods Mol Biol. 1998;80:69-79. No abstract available.

PMID:
9664364
15.

Production and characterization of antibodies against synthetic peptides.

Hancock DC, Evan GI.

Methods Mol Biol. 1998;80:15-22. No abstract available.

PMID:
9664360
16.

FosB in the suprachiasmatic nucleus of the Syrian and Siberian hamster.

Ebling FJ, Maywood ES, Mehta M, Hancock DC, McNulty S, De Bono J, Bray SJ, Hastings MH.

Brain Res Bull. 1996;41(5):257-68.

PMID:
8924036
17.

Synthetic peptides in biochemical research.

Hancock DC, O'Reilly NJ, Evan GI.

Mol Biotechnol. 1995 Aug;4(1):73-86. Review.

PMID:
8521041
18.

A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins.

Littlewood TD, Hancock DC, Danielian PS, Parker MG, Evan GI.

Nucleic Acids Res. 1995 May 25;23(10):1686-90.

19.

Down-regulation of the c-myc proto-oncogene in inhibition of vascular smooth-muscle cell proliferation: a signal for growth arrest?

Bennett MR, Littlewood TD, Hancock DC, Evan GI, Newby AC.

Biochem J. 1994 Sep 15;302 ( Pt 3):701-8.

20.

Adenine phosphoribosyltransferase deficiency with renal deposition of 2,8-dihydroxyadenine leading to nephrolithiasis and chronic renal failure.

Fye KH, Sahota A, Hancock DC, Gelb AB, Chen J, Sparks JW, Sibley RK, Tischfield JA.

Arch Intern Med. 1993 Mar 22;153(6):767-70.

PMID:
8447714
21.

Expression of c-fos in regions of the basal limbic forebrain following intracerebroventricular corticotropin-releasing factor in unstressed or stressed male rats.

Arnold FJ, De Lucas Bueno M, Shiers H, Hancock DC, Evan GI, Herbert J.

Neuroscience. 1992 Nov;51(2):377-90.

PMID:
1465198
22.

Renal insufficiency secondary to 2,8-dihydroxyadenine urolithiasis.

Gelb AB, Fye KH, Tischfield JA, Sahota AS, Sparks JW, Hancock DC, Sibley RK.

Hum Pathol. 1992 Sep;23(9):1081-5.

PMID:
1516930
23.

Induction of apoptosis in fibroblasts by c-myc protein.

Evan GI, Wyllie AH, Gilbert CS, Littlewood TD, Land H, Brooks M, Waters CM, Penn LZ, Hancock DC.

Cell. 1992 Apr 3;69(1):119-28.

PMID:
1555236
24.

Production and characterization of antibodies against synthetic peptides.

Hancock DC, Evan GI.

Methods Mol Biol. 1992;10:33-41. doi: 10.1385/0-89603-204-3:33.

PMID:
23150294
25.

Synthesis of peptides for use as immunogens.

Hancock DC, Evan GI.

Methods Mol Biol. 1992;10:23-32. doi: 10.1385/0-89603-204-3:23.

PMID:
23150293
26.

Production and characterization of antibodies against synthetic peptides.

Hancock DC, Evan GI.

Methods Mol Biol. 1992;80:33-41. doi: 10.1385/0-89603-204-3:33.

PMID:
22351197
27.

Synthesis of peptides for use as immunogens.

Hancock DC, Evan GI.

Methods Mol Biol. 1992;80:23-32. doi: 10.1385/0-89603-204-3:23.

PMID:
22351196
28.

The role of N-methyl-d-aspartate-type glutamatergic neurotransmission in the photic induction of immediate-early gene expression in the suprachiasmatic nuclei of the Syrian hamster.

Ebling FJ, Maywood ES, Staley K, Humby T, Hancock DC, Waters CM, Evant GI, Hastings MH.

J Neuroendocrinol. 1991 Dec 1;3(6):641-52. doi: 10.1111/j.1365-2826.1991.tb00329.x.

PMID:
19215534
29.

c-myc protein expression in untransformed fibroblasts.

Waters CM, Littlewood TD, Hancock DC, Moore JP, Evan GI.

Oncogene. 1991 May;6(5):797-805.

PMID:
2052358
30.
31.
32.

A sensitive enzyme-linked immunosorbence assay for the c-fos and v-fos oncoproteins.

Moore JP, Littlewood TD, Hancock DC, Evan GI.

Biochim Biophys Acta. 1988 Apr 14;965(1):60-7.

PMID:
3126820
33.

Immunological probes in the analysis of myc protein expression.

Evan GI, Moore JP, Ibson JM, Waters CM, Hancock DC, Littlewood TD.

Curr Top Microbiol Immunol. 1988;141:189-201. No abstract available.

PMID:
3063442
34.

Characterization of a heat shock-induced insoluble complex in the nuclei of cells.

Littlewood TD, Hancock DC, Evan GI.

J Cell Sci. 1987 Aug;88 ( Pt 1):65-72.

35.

A sensitive and quantitative enzyme-linked immunosorbence assay for the c-myc and N-myc oncoproteins.

Moore JP, Hancock DC, Littlewood TD, Evan GI.

Oncogene Res. 1987;2(1):65-80.

PMID:
3333275
36.
37.

Characterisation of human myc proteins.

Evan GI, Hancock DC, Littlewood TD, Gee NS.

Curr Top Microbiol Immunol. 1986;132:362-74. No abstract available.

PMID:
3539540
38.

Characterization of the human c-myc protein using antibodies prepared against synthetic peptides.

Evan GI, Hancock DC, Littlewood T, Pauza CD.

Ciba Found Symp. 1986;119:245-63. Review.

PMID:
3525040
40.

Intestinal barrier to large particulates in mice.

LeFevre ME, Hancock DC, Joel DD.

J Toxicol Environ Health. 1980 Jul;6(4):691-704.

PMID:
7420474
41.

Histochemical studies of wound healing in the hair-loss mouse.

Hancock DC Jr, Wilber CG, Nash DJ.

Z Rechtsmed. 1978 Nov 10;82(2):121-7. No abstract available.

PMID:
735445

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