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Items: 22


The promise and challenges of immune agonist antibody development in cancer.

Mayes PA, Hance KW, Hoos A.

Nat Rev Drug Discov. 2018 Jul;17(7):509-527. doi: 10.1038/nrd.2018.75. Epub 2018 Jun 15. Review.


Enhanced preclinical antitumor activity of M7824, a bifunctional fusion protein simultaneously targeting PD-L1 and TGF-╬▓.

Lan Y, Zhang D, Xu C, Hance KW, Marelli B, Qi J, Yu H, Qin G, Sircar A, Hernández VM, Jenkins MH, Fontana RE, Deshpande A, Locke G, Sabzevari H, Radvanyi L, Lo KM.

Sci Transl Med. 2018 Jan 17;10(424). pii: eaan5488. doi: 10.1126/scitranslmed.aan5488.


Cutting edge: epigenetic regulation of Foxp3 defines a stable population of CD4+ regulatory T cells in tumors from mice and humans.

Waight JD, Takai S, Marelli B, Qin G, Hance KW, Zhang D, Tighe R, Lan Y, Lo KM, Sabzevari H, Hofmeister R, Wilson NS.

J Immunol. 2015 Feb 1;194(3):878-82. doi: 10.4049/jimmunol.1402725. Epub 2014 Dec 29.


Serum macrophage inhibitory cytokine-1 (MIC-1/GDF15): a potential screening tool for the prevention of colon cancer?

Brown DA, Hance KW, Rogers CJ, Sansbury LB, Albert PS, Murphy G, Laiyemo AO, Wang Z, Cross AJ, Schatzkin A, Danta M, Srasuebkul P, Amin J, Law M, Breit SN, Lanza E.

Cancer Epidemiol Biomarkers Prev. 2012 Feb;21(2):337-46. doi: 10.1158/1055-9965.EPI-11-0786. Epub 2011 Dec 5.


Analysis of circulating regulatory T cells in patients with metastatic prostate cancer pre- versus post-vaccination.

Vergati M, Cereda V, Madan RA, Gulley JL, Huen NY, Rogers CJ, Hance KW, Arlen PM, Schlom J, Tsang KY.

Cancer Immunol Immunother. 2011 Feb;60(2):197-206. doi: 10.1007/s00262-010-0927-9. Epub 2010 Oct 26.


Intratumoral immunotherapy of established solid tumors with chitosan/IL-12.

Zaharoff DA, Hance KW, Rogers CJ, Schlom J, Greiner JW.

J Immunother. 2010 Sep;33(7):697-705. doi: 10.1097/CJI.0b013e3181eb826d.


Serum adiponectin, leptin, C-peptide, homocysteine, and colorectal adenoma recurrence in the Polyp Prevention Trial.

Bobe G, Murphy G, Rogers CJ, Hance KW, Albert PS, Laiyemo AO, Sansbury LB, Lanza E, Schatzkin A, Cross AJ.

Cancer Epidemiol Biomarkers Prev. 2010 Jun;19(6):1441-52. doi: 10.1158/1055-9965.EPI-09-1082. Epub 2010 May 25.


Intravesical immunotherapy of superficial bladder cancer with chitosan/interleukin-12.

Zaharoff DA, Hoffman BS, Hooper HB, Benjamin CJ Jr, Khurana KK, Hance KW, Rogers CJ, Pinto PA, Schlom J, Greiner JW.

Cancer Res. 2009 Aug 1;69(15):6192-9. doi: 10.1158/0008-5472.CAN-09-1114. Epub 2009 Jul 28.


The antitumor and immunoadjuvant effects of IFN-alpha in combination with recombinant poxvirus vaccines.

Hance KW, Rogers CJ, Zaharoff DA, Canter D, Schlom J, Greiner JW.

Clin Cancer Res. 2009 Apr 1;15(7):2387-96. doi: 10.1158/1078-0432.CCR-08-1752. Epub 2009 Mar 10.


Effects of MAPK signaling on 1,25-dihydroxyvitamin D-mediated CYP24 gene expression in the enterocyte-like cell line, Caco-2.

Cui M, Zhao Y, Hance KW, Shao A, Wood RJ, Fleet JC.

J Cell Physiol. 2009 Apr;219(1):132-42. doi: 10.1002/jcp.21657.


Exercise enhances vaccine-induced antigen-specific T cell responses.

Rogers CJ, Zaharoff DA, Hance KW, Perkins SN, Hursting SD, Schlom J, Greiner JW.

Vaccine. 2008 Oct 3;26(42):5407-15. doi: 10.1016/j.vaccine.2008.07.081. Epub 2008 Aug 14.


Vaccination with a recombinant Saccharomyces cerevisiae expressing a tumor antigen breaks immune tolerance and elicits therapeutic antitumor responses.

Wansley EK, Chakraborty M, Hance KW, Bernstein MB, Boehm AL, Guo Z, Quick D, Franzusoff A, Greiner JW, Schlom J, Hodge JW.

Clin Cancer Res. 2008 Jul 1;14(13):4316-25. doi: 10.1158/1078-0432.CCR-08-0393.


Energy restriction and exercise differentially enhance components of systemic and mucosal immunity in mice.

Rogers CJ, Berrigan D, Zaharoff DA, Hance KW, Patel AC, Perkins SN, Schlom J, Greiner JW, Hursting SD.

J Nutr. 2008 Jan;138(1):115-22.


Chitosan solution enhances the immunoadjuvant properties of GM-CSF.

Zaharoff DA, Rogers CJ, Hance KW, Schlom J, Greiner JW.

Vaccine. 2007 Dec 17;25(52):8673-86. Epub 2007 Nov 5.


Combination of physical activity, nutrition, or other metabolic factors and vaccine response.

Hance KW, Rogers CJ, Hursting SD, Greiner JW.

Front Biosci. 2007 Sep 1;12:4997-5029. Review.


Chitosan solution enhances both humoral and cell-mediated immune responses to subcutaneous vaccination.

Zaharoff DA, Rogers CJ, Hance KW, Schlom J, Greiner JW.

Vaccine. 2007 Mar 1;25(11):2085-94. Epub 2006 Dec 4.


Nucleo-cytoplasmic cycling of the vitamin D receptor in the enterocyte-like cell line, Caco-2.

Klopot A, Hance KW, Peleg S, Barsony J, Fleet JC.

J Cell Biochem. 2007 Feb 15;100(3):617-28.


Epidemiology of inflammatory breast cancer (IBC).

Anderson WF, Schairer C, Chen BE, Hance KW, Levine PH.

Breast Dis. 2005-2006;22:9-23. Review.


Vitamin D-inducible calcium transport and gene expression in three Caco-2 cell lines.

Fleet JC, Eksir F, Hance KW, Wood RJ.

Am J Physiol Gastrointest Liver Physiol. 2002 Sep;283(3):G618-25.

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