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Toxicogenomic analysis of publicly available transcriptomic data can predict food, drugs, and chemical-induced asthma.

Hachim MY, Hachim IY, Elemam NM, Hamoudi RA.

Pharmgenomics Pers Med. 2019 Aug 26;12:181-199. doi: 10.2147/PGPM.S217535. eCollection 2019.


Gasdermin D Hypermethylation Inhibits Pyroptosis And LPS-Induced IL-1β Release From NK92 Cells.

Muhammad JS, Jayakumar MN, Elemam NM, Venkatachalam T, Raju TK, Hamoudi RA, Maghazachi AA.

Immunotargets Ther. 2019 Oct 14;8:29-41. doi: 10.2147/ITT.S219867. eCollection 2019.


The Personal Genome Project-UK, an open access resource of human multi-omics data.

Chervova O, Conde L, Guerra-Assunção JA, Moghul I, Webster AP, Berner A, Larose Cadieux E, Tian Y, Voloshin V, Jesus TF, Hamoudi R, Herrero J, Beck S.

Sci Data. 2019 Oct 31;6(1):257. doi: 10.1038/s41597-019-0205-4.


The FTO genetic variants are associated with dietary intake and body mass index amongst Emirati population.

Saber-Ayad M, Manzoor S, Radwan H, Hammoudeh S, Wardeh R, Ashraf A, Jabbar H, Hamoudi R.

PLoS One. 2019 Oct 17;14(10):e0223808. doi: 10.1371/journal.pone.0223808. eCollection 2019.


Reduced Expression of Chl1 gene Impairs Insulin Secretion by Down-Regulating the Expression of Key Molecules of β-cell Function.

Taneera J, Dhaiban S, Hachim M, Mohammed AK, Mukhopadhyay D, Bajbouj K, Hamoudi R, Salehi A, Hamad M.

Exp Clin Endocrinol Diabetes. 2019 Oct 15. doi: 10.1055/a-1014-2544. [Epub ahead of print]


Calibrated Automated Thrombogram During Pregnancy in Unexplained Recurrent Miscarriages: A Pilot Study.

Elias A, Hamoudi R, Schwartz N, Ron G, Elias M.

Isr Med Assoc J. 2019 Oct;21(10):681-685.


Comparative metabolomics of MCF-7 breast cancer cells using different extraction solvents assessed by mass spectroscopy.

Semreen MH, Alniss HY, Grgic SR, El-Awady RA, Almehdi AH, Mousa MK, Hamoudi RA.

Sci Rep. 2019 Sep 11;9(1):13126. doi: 10.1038/s41598-019-49509-y.


Logistic regression prediction model identify type 2 diabetes mellitus as a prognostic factor for human papillomavirus-16 associated head and neck squamous cell carcinoma.

Sobti A, Sharif-Askari FS, Khan S, Sharif-Askari NS, Hachim MY, Williams L, Zhou Y, Hopper C, Hamoudi R.

PLoS One. 2019 May 16;14(5):e0217000. doi: 10.1371/journal.pone.0217000. eCollection 2019.


High TNFRSF14 and low BTLA are associated with poor prognosis in Follicular Lymphoma and in Diffuse Large B-cell Lymphoma transformation.

Carreras J, Lopez-Guillermo A, Kikuti YY, Itoh J, Masashi M, Ikoma H, Tomita S, Hiraiwa S, Hamoudi R, Rosenwald A, Leich E, Martinez A, Roncador G, Villamor N, Colomo L, Perez P, Tsuji NM, Campo E, Nakamura N.

J Clin Exp Hematop. 2019;59(1):1-16. doi: 10.3960/jslrt.19003.


High-throughput quantification of the effect of DMSO on the viability of lung and breast cancer cells using an easy-to-use spectrophotometric trypan blue-based assay.

Hammoudeh SM, Hammoudeh AM, Hamoudi R.

Histochem Cell Biol. 2019 Jul;152(1):75-84. doi: 10.1007/s00418-019-01775-7. Epub 2019 Feb 16.


Correlation of securin and Ki67 in invasive breast carcinoma.

Talaat IM, Hamoudi RA, Yakout NM, Oweiss NY, Omar AM.

Histol Histopathol. 2019 Jun;34(6):697-709. doi: 10.14670/HH-18-071. Epub 2018 Dec 3.


Association Trends Between Antihypertensive Drug Therapies and Diastolic Hypotension in Emirati Patients with Type 2 Diabetes: A Single-Center Retrospective Longitudinal Study.

Mussa BM, Hamoudi RA, Abusnana SE.

Diabetes Ther. 2018 Oct;9(5):1853-1868. doi: 10.1007/s13300-018-0469-2. Epub 2018 Jul 24.


Using antibody directed phototherapy to target oesophageal adenocarcinoma with heterogeneous HER2 expression.

Pye H, Butt MA, Funnell L, Reinert HW, Puccio I, Rehman Khan SU, Saouros S, Marklew JS, Stamati I, Qurashi M, Haidry R, Sehgal V, Oukrif D, Gandy M, Whitaker HC, Rodriguez-Justo M, Novelli M, Hamoudi R, Yahioglu G, Deonarain MP, Lovat LB.

Oncotarget. 2018 May 1;9(33):22945-22959. doi: 10.18632/oncotarget.25159. eCollection 2018 May 1.


Immunohistochemical assessment of Survivin and Bcl3 expression as potential biomarkers for NF-κB activation in the Barrett metaplasia-dysplasia-adenocarcinoma sequence.

Puccio I, Khan S, Butt A, Graham D, Sehgal V, Patel D, Novelli M, Lovat LB, Rodriguez-Justo M, Hamoudi RA.

Int J Exp Pathol. 2018 Feb;99(1):10-14. doi: 10.1111/iep.12260. Epub 2018 Feb 23.


Magnetically responsive microbubbles as delivery vehicles for targeted sonodynamic and antimetabolite therapy of pancreatic cancer.

Sheng Y, Beguin E, Nesbitt H, Kamila S, Owen J, Barnsley LC, Callan B, O'Kane C, Nomikou N, Hamoudi R, Taylor MA, Love M, Kelly P, O'Rourke D, Stride E, McHale AP, Callan JF.

J Control Release. 2017 Sep 28;262:192-200. doi: 10.1016/j.jconrel.2017.07.040. Epub 2017 Jul 29.


Management of Radiologically Indeterminate Magnetic Resonance Imaging Signals in Men at Risk of Prostate Cancer.

van der Sar ECA, Kasivisvanathan V, Brizmohun M, Freeman A, Punwani S, Hamoudi R, Emberton M.

Eur Urol Focus. 2019 Jan;5(1):62-68. doi: 10.1016/j.euf.2017.03.016. Epub 2017 Apr 19.


Systematic assessment with I-SCAN magnification endoscopy and acetic acid improves dysplasia detection in patients with Barrett's esophagus.

Lipman G, Bisschops R, Sehgal V, Ortiz-Fernández-Sordo J, Sweis R, Esteban JM, Hamoudi R, Banks MR, Ragunath K, Lovat LB, Haidry RJ.

Endoscopy. 2017 Dec;49(12):1219-1228. doi: 10.1055/s-0043-113441. Epub 2017 Jul 21.


Efficacy of photochemical internalisation using disulfonated chlorin and porphyrin photosensitisers: An in vitro study in 2D and 3D prostate cancer models.

Martinez de Pinillos Bayona A, Woodhams JH, Pye H, Hamoudi RA, Moore CM, MacRobert AJ.

Cancer Lett. 2017 May 1;393:68-75. doi: 10.1016/j.canlet.2017.02.018. Epub 2017 Feb 20.


Upregulation of mucin glycoprotein MUC1 in the progression to esophageal adenocarcinoma and therapeutic potential with a targeted photoactive antibody-drug conjugate.

Adil Butt M, Pye H, Haidry RJ, Oukrif D, Khan SU, Puccio I, Gandy M, Reinert HW, Bloom E, Rashid M, Yahioglu G, Deonarain MP, Hamoudi R, Rodriguez-Justo M, Novelli MR, Lovat LB.

Oncotarget. 2017 Apr 11;8(15):25080-25096. doi: 10.18632/oncotarget.15340.


A HER2 selective theranostic agent for surgical resection guidance and photodynamic therapy.

Pye H, Butt MA, Reinert HW, Maruani A, Nunes JP, Marklew JS, Qurashi M, Funnell L, May A, Stamati I, Hamoudi R, Baker JR, Smith ME, Caddick S, Deonarain MP, Yahioglu G, Chudasama V, Lovat LB.

Photochem Photobiol Sci. 2016 Oct 5;15(10):1227-1238. Epub 2016 Aug 9.


Disulfonated tetraphenyl chlorin (TPCS2a)-induced photochemical internalisation of bleomycin in patients with solid malignancies: a phase 1, dose-escalation, first-in-man trial.

Sultan AA, Jerjes W, Berg K, Høgset A, Mosse CA, Hamoudi R, Hamdoon Z, Simeon C, Carnell D, Forster M, Hopper C.

Lancet Oncol. 2016 Sep;17(9):1217-29. doi: 10.1016/S1470-2045(16)30224-8. Epub 2016 Jul 28.


Saturation analysis for whole-genome bisulfite sequencing data.

Libertini E, Heath SC, Hamoudi RA, Gut M, Ziller MJ, Herrero J, Czyz A, Ruotti V, Stunnenberg HG, Frontini M, Ouwehand WH, Meissner A, Gut IG, Beck S.

Nat Biotechnol. 2016 Jul;34(7):691-693. doi: 10.1038/nbt.3524. Epub 2016 Jun 27. No abstract available.


Information recovery from low coverage whole-genome bisulfite sequencing.

Libertini E, Heath SC, Hamoudi RA, Gut M, Ziller MJ, Czyz A, Ruotti V, Stunnenberg HG, Frontini M, Ouwehand WH, Meissner A, Gut IG, Beck S.

Nat Commun. 2016 Jun 27;7:11306. doi: 10.1038/ncomms11306.


Gigantic vascular anomaly in a PHACE syndrome patient managed with photodynamic therapy.

Jerjes W, Hamdoon Z, Hamoudi R, Al-Khawalde M, Hopper C.

Photodiagnosis Photodyn Ther. 2016 Sep;15:79-82. doi: 10.1016/j.pdpdt.2016.05.007. Epub 2016 May 24. No abstract available.


Combined sonodynamic and antimetabolite therapy for the improved treatment of pancreatic cancer using oxygen loaded microbubbles as a delivery vehicle.

McEwan C, Kamila S, Owen J, Nesbitt H, Callan B, Borden M, Nomikou N, Hamoudi RA, Taylor MA, Stride E, McHale AP, Callan JF.

Biomaterials. 2016 Feb;80:20-32. doi: 10.1016/j.biomaterials.2015.11.033. Epub 2015 Nov 26.


Diagnostic value of H3F3A mutations in giant cell tumour of bone compared to osteoclast-rich mimics.

Presneau N, Baumhoer D, Behjati S, Pillay N, Tarpey P, Campbell PJ, Jundt G, Hamoudi R, Wedge DC, Loo PV, Hassan AB, Khatri B, Ye H, Tirabosco R, Amary MF, Flanagan AM.

J Pathol Clin Res. 2015 Mar 16;1(2):113-23. doi: 10.1002/cjp2.13. eCollection 2015 Apr.


Variation in pre-PCR processing of FFPE samples leads to discrepancies in BRAF and EGFR mutation detection: a diagnostic RING trial.

Kapp JR, Diss T, Spicer J, Gandy M, Schrijver I, Jennings LJ, Li MM, Tsongalis GJ, de Castro DG, Bridge JA, Wallace A, Deignan JL, Hing S, Butler R, Verghese E, Latham GJ, Hamoudi RA.

J Clin Pathol. 2015 Feb;68(2):111-8. doi: 10.1136/jclinpath-2014-202644. Epub 2014 Nov 27.


Anaplastic large cell lymphoma-propagating cells are detectable by side population analysis and possess an expression profile reflective of a primitive origin.

Moti N, Malcolm T, Hamoudi R, Mian S, Garland G, Hook CE, Burke GA, Wasik MA, Merkel O, Kenner L, Laurenti E, Dick JE, Turner SD.

Oncogene. 2015 Apr 2;34(14):1843-52. doi: 10.1038/onc.2014.112. Epub 2014 May 12.


Spatiotemporal characterizations of dengue virus in mainland China: insights into the whole genome from 1978 to 2011.

Zhang H, Zhang Y, Hamoudi R, Yan G, Chen X, Zhou Y.

PLoS One. 2014 Feb 14;9(2):e87630. doi: 10.1371/journal.pone.0087630. eCollection 2014.


Wild-type K-ras has a tumour suppressor effect on carcinogen-induced murine colorectal adenoma formation.

Luo F, Poulogiannis G, Ye H, Hamoudi R, Dong G, Zhang W, Ibrahim AE, Arends MJ.

Int J Exp Pathol. 2014 Feb;95(1):8-15. doi: 10.1111/iep.12064. Epub 2013 Dec 20.


Key differences identified between actinic keratosis and cutaneous squamous cell carcinoma by transcriptome profiling.

Lambert SR, Mladkova N, Gulati A, Hamoudi R, Purdie K, Cerio R, Leigh I, Proby C, Harwood CA.

Br J Cancer. 2014 Jan 21;110(2):520-9. doi: 10.1038/bjc.2013.760. Epub 2013 Dec 12.


Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone.

Behjati S, Tarpey PS, Presneau N, Scheipl S, Pillay N, Van Loo P, Wedge DC, Cooke SL, Gundem G, Davies H, Nik-Zainal S, Martin S, McLaren S, Goodie V, Robinson B, Butler A, Teague JW, Halai D, Khatri B, Myklebost O, Baumhoer D, Jundt G, Hamoudi R, Tirabosco R, Amary MF, Futreal PA, Stratton MR, Campbell PJ, Flanagan AM.

Nat Genet. 2013 Dec;45(12):1479-82. doi: 10.1038/ng.2814. Epub 2013 Oct 27. Erratum in: Nat Genet. 2014 Mar;46(3):316. Goodie, Victoria [corrected to Goody, Victoria].


Simultaneous bilateral torsion of the adnexae in an adult female without any history of ovarian stimulation.

Abdusamad K, Hamoudi R, Maiti S.

BMJ Case Rep. 2013 Jan 30;2013. pii: bcr2012007909. doi: 10.1136/bcr-2012-007909.


An integrated genomic and expression analysis of 7q deletion in splenic marginal zone lymphoma.

Watkins AJ, Hamoudi RA, Zeng N, Yan Q, Huang Y, Liu H, Zhang J, Braggio E, Fonseca R, de Leval L, Isaacson PG, Wotherspoon A, McPhail ED, Dogan A, Du MQ.

PLoS One. 2012;7(9):e44997. doi: 10.1371/journal.pone.0044997. Epub 2012 Sep 13.


Predicting sustained viral response to hepatitis C using a rapid and simple IL28B rs8099917 genotyping assay.

Li W, Zeng Y, Wang J, Zhou B, Zhang J, Zhang H, Li J, Wu Y, Hamoudi R, Zhou Y.

Antiviral Res. 2012 Apr;94(1):54-6. doi: 10.1016/j.antiviral.2012.02.007. Epub 2012 Feb 22.


A20 inactivation in ocular adnexal MALT lymphoma.

Bi Y, Zeng N, Chanudet E, Huang Y, Hamoudi RA, Liu H, Dong G, Watkins AJ, Ley SC, Zou L, Chen R, Zhu X, Du MQ.

Haematologica. 2012 Jun;97(6):926-30. doi: 10.3324/haematol.2010.036798. Epub 2011 Dec 29.


BCR and TLR signaling pathways are recurrently targeted by genetic changes in splenic marginal zone lymphomas.

Yan Q, Huang Y, Watkins AJ, Kocialkowski S, Zeng N, Hamoudi RA, Isaacson PG, de Leval L, Wotherspoon A, Du MQ.

Haematologica. 2012 Apr;97(4):595-8. doi: 10.3324/haematol.2011.054080. Epub 2011 Nov 18.


MGMT CpG island is invariably methylated in adult astrocytic and oligodendroglial tumors with IDH1 or IDH2 mutations.

Mulholland S, Pearson DM, Hamoudi RA, Malley DS, Smith CM, Weaver JM, Jones DT, Kocialkowski S, Bäcklund LM, Collins VP, Ichimura K.

Int J Cancer. 2012 Sep 1;131(5):1104-13. doi: 10.1002/ijc.26499. Epub 2012 Jan 11.


BIOMED-2 PCR assays for IGK gene rearrangements are essential for B-cell clonality analysis in follicular lymphoma.

Payne K, Wright P, Grant JW, Huang Y, Hamoudi R, Bacon CM, Du MQ, Liu H.

Br J Haematol. 2011 Oct;155(1):84-92. doi: 10.1111/j.1365-2141.2011.08803.x. Epub 2011 Jul 26.


Synergism between K-rasVal12 and mutant Apc accelerates murine large intestinal tumourigenesis.

Luo F, Poulogiannis G, Ye H, Hamoudi R, Arends MJ.

Oncol Rep. 2011 Jul;26(1):125-33. doi: 10.3892/or.2011.1288. Epub 2011 Apr 29.


A distinct region of the MGMT CpG island critical for transcriptional regulation is preferentially methylated in glioblastoma cells and xenografts.

Malley DS, Hamoudi RA, Kocialkowski S, Pearson DM, Collins VP, Ichimura K.

Acta Neuropathol. 2011 May;121(5):651-61. doi: 10.1007/s00401-011-0803-5. Epub 2011 Feb 3.


Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation.

Rosebeck S, Madden L, Jin X, Gu S, Apel IJ, Appert A, Hamoudi RA, Noels H, Sagaert X, Van Loo P, Baens M, Du MQ, Lucas PC, McAllister-Lucas LM.

Science. 2011 Jan 28;331(6016):468-72. doi: 10.1126/science.1198946. Erratum in: Science. 2011 Apr 22;332(6028):421.


A20, ABIN-1/2, and CARD11 mutations and their prognostic value in gastrointestinal diffuse large B-cell lymphoma.

Dong G, Chanudet E, Zeng N, Appert A, Chen YW, Au WY, Hamoudi RA, Watkins AJ, Ye H, Liu H, Gao Z, Chuang SS, Srivastava G, Du MQ.

Clin Cancer Res. 2011 Mar 15;17(6):1440-51. doi: 10.1158/1078-0432.CCR-10-1859. Epub 2011 Jan 25.


Mutant K-ras promotes carcinogen-induced murine colorectal tumourigenesis, but does not alter tumour chromosome stability.

Luo F, Poulogiannis G, Ye H, Hamoudi R, Zhang W, Dong G, Arends MJ.

J Pathol. 2011 Feb;223(3):390-9. doi: 10.1002/path.2790. Epub 2010 Nov 11.


Primary effusion lymphoma: genomic profiling revealed amplification of SELPLG and CORO1C encoding for proteins important for cell migration.

Luan SL, Boulanger E, Ye H, Chanudet E, Johnson N, Hamoudi RA, Bacon CM, Liu H, Huang Y, Said J, Chu P, Clemen CS, Cesarman E, Chadburn A, Isaacson PG, Du MQ.

J Pathol. 2010 Oct;222(2):166-79. doi: 10.1002/path.2752.


Differential expression of NF-kappaB target genes in MALT lymphoma with and without chromosome translocation: insights into molecular mechanism.

Hamoudi RA, Appert A, Ye H, Ruskone-Fourmestraux A, Streubel B, Chott A, Raderer M, Gong L, Wlodarska I, De Wolf-Peeters C, MacLennan KA, de Leval L, Isaacson PG, Du MQ.

Leukemia. 2010 Aug;24(8):1487-97. doi: 10.1038/leu.2010.118. Epub 2010 Jun 3.


K-ras exon 4A has a tumour suppressor effect on carcinogen-induced murine colonic adenoma formation.

Luo F, Ye H, Hamoudi R, Dong G, Zhang W, Patek CE, Poulogiannis G, Arends MJ.

J Pathol. 2010 Apr;220(5):542-50. doi: 10.1002/path.2672.


Splenic marginal zone lymphoma: characterization of 7q deletion and its value in diagnosis.

Watkins AJ, Huang Y, Ye H, Chanudet E, Johnson N, Hamoudi R, Liu H, Dong G, Attygalle A, McPhail ED, Law ME, Isaacson PG, de Leval L, Wotherspoon A, Du MQ.

J Pathol. 2010 Mar;220(4):461-74. doi: 10.1002/path.2665.


Continual monitoring of intraepithelial lymphocyte immunophenotype and clonality is more important than snapshot analysis in the surveillance of refractory coeliac disease.

Liu H, Brais R, Lavergne-Slove A, Jeng Q, Payne K, Ye H, Liu Z, Carreras J, Huang Y, Bacon CM, Hamoudi RA, Save V, Venkatraman L, Isaacson PG, Woodward J, Du MQ.

Gut. 2010 Apr;59(4):452-60. doi: 10.1136/gut.2009.186007. Epub 2009 Dec 8.


Prognostic relevance of DNA copy number changes in colorectal cancer.

Poulogiannis G, Ichimura K, Hamoudi RA, Luo F, Leung SY, Yuen ST, Harrison DJ, Wyllie AH, Arends MJ.

J Pathol. 2010 Feb;220(3):338-47. doi: 10.1002/path.2640.


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