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Items: 1 to 50 of 63

1.

Recurrent tumor-specific regulation of alternative polyadenylation of cancer-related genes.

Xue Z, Warren RL, Gibb EA, MacMillan D, Wong J, Chiu R, Hammond SA, Yang C, Nip KM, Ennis CA, Hahn A, Reynolds S, Birol I.

BMC Genomics. 2018 Jul 13;19(1):536. doi: 10.1186/s12864-018-4903-7.

2.

Potent Immune Modulation by MEDI6383, an Engineered Human OX40 Ligand IgG4P Fc Fusion Protein.

Oberst MD, Augé C, Morris C, Kentner S, Mulgrew K, McGlinchey K, Hair J, Hanabuchi S, Du Q, Damschroder M, Feng H, Eck S, Buss N, de Haan L, Pierce AJ, Park H, Sylwester A, Axthelm MK, Picker L, Morris NP, Weinberg A, Hammond SA.

Mol Cancer Ther. 2018 May;17(5):1024-1038. doi: 10.1158/1535-7163.MCT-17-0200. Epub 2018 Mar 15.

PMID:
29545330
3.

A novel approach to wildlife transcriptomics provides evidence of disease-mediated differential expression and changes to the microbiome of amphibian populations.

Campbell LJ, Hammond SA, Price SJ, Sharma MD, Garner TWJ, Birol I, Helbing CC, Wilfert L, Griffiths AGF.

Mol Ecol. 2018 Mar;27(6):1413-1427. doi: 10.1111/mec.14528. Epub 2018 Mar 29.

PMID:
29420865
4.

The Genome of the Beluga Whale (Delphinapterus leucas).

Jones SJM, Taylor GA, Chan S, Warren RL, Hammond SA, Bilobram S, Mordecai G, Suttle CA, Miller KM, Schulze A, Chan AM, Jones SJ, Tse K, Li I, Cheung D, Mungall KL, Choo C, Ally A, Dhalla N, Tam AKY, Troussard A, Kirk H, Pandoh P, Paulino D, Coope RJN, Mungall AJ, Moore R, Zhao Y, Birol I, Ma Y, Marra M, Haulena M.

Genes (Basel). 2017 Dec 11;8(12). pii: E378. doi: 10.3390/genes8120378.

5.

The Genome of the Northern Sea Otter (Enhydra lutris kenyoni).

Jones SJ, Haulena M, Taylor GA, Chan S, Bilobram S, Warren RL, Hammond SA, Mungall KL, Choo C, Kirk H, Pandoh P, Ally A, Dhalla N, Tam AKY, Troussard A, Paulino D, Coope RJN, Mungall AJ, Moore R, Zhao Y, Birol I, Ma Y, Marra M, Jones SJM.

Genes (Basel). 2017 Dec 11;8(12). pii: E379. doi: 10.3390/genes8120379.

6.

Combination therapy with an OX40L fusion protein and a vaccine targeting the transcription factor twist inhibits metastasis in a murine model of breast cancer.

Malamas AS, Hammond SA, Schlom J, Hodge JW.

Oncotarget. 2017 Aug 5;8(53):90825-90841. doi: 10.18632/oncotarget.19967. eCollection 2017 Oct 31.

7.

The North American bullfrog draft genome provides insight into hormonal regulation of long noncoding RNA.

Hammond SA, Warren RL, Vandervalk BP, Kucuk E, Khan H, Gibb EA, Pandoh P, Kirk H, Zhao Y, Jones M, Mungall AJ, Coope R, Pleasance S, Moore RA, Holt RA, Round JM, Ohora S, Walle BV, Veldhoen N, Helbing CC, Birol I.

Nat Commun. 2017 Nov 10;8(1):1433. doi: 10.1038/s41467-017-01316-7.

8.

Enhanced immunotherapy by combining a vaccine with a novel murine GITR ligand fusion protein.

Morillon YM 2nd, Hammond SA, Durham NM, Schlom J, Greiner JW.

Oncotarget. 2017 Sep 7;8(43):73469-73482. doi: 10.18632/oncotarget.20703. eCollection 2017 Sep 26.

9.

Concurrent PD-1 Blockade Negates the Effects of OX40 Agonist Antibody in Combination Immunotherapy through Inducing T-cell Apoptosis.

Shrimali RK, Ahmad S, Verma V, Zeng P, Ananth S, Gaur P, Gittelman RM, Yusko E, Sanders C, Robins H, Hammond SA, Janik JE, Mkrtichyan M, Gupta S, Khleif SN.

Cancer Immunol Res. 2017 Sep;5(9):755-766. doi: 10.1158/2326-6066.CIR-17-0292.

10.

Oncolytic VSV Primes Differential Responses to Immuno-oncology Therapy.

Durham NM, Mulgrew K, McGlinchey K, Monks NR, Ji H, Herbst R, Suzich J, Hammond SA, Kelly EJ.

Mol Ther. 2017 Aug 2;25(8):1917-1932. doi: 10.1016/j.ymthe.2017.05.006. Epub 2017 Jun 2.

11.

ABySS 2.0: resource-efficient assembly of large genomes using a Bloom filter.

Jackman SD, Vandervalk BP, Mohamadi H, Chu J, Yeo S, Hammond SA, Jahesh G, Khan H, Coombe L, Warren RL, Birol I.

Genome Res. 2017 May;27(5):768-777. doi: 10.1101/gr.214346.116. Epub 2017 Feb 23.

12.

De novo assembly of the ringed seal (Pusa hispida) blubber transcriptome: A tool that enables identification of molecular health indicators associated with PCB exposure.

Brown TM, Hammond SA, Behsaz B, Veldhoen N, Birol I, Helbing CC.

Aquat Toxicol. 2017 Apr;185:48-57. doi: 10.1016/j.aquatox.2017.02.004. Epub 2017 Feb 3.

PMID:
28187360
13.

Kollector: transcript-informed, targeted de novo assembly of gene loci.

Kucuk E, Chu J, Vandervalk BP, Hammond SA, Warren RL, Birol I.

Bioinformatics. 2017 Jun 15;33(12):1782-1788. doi: 10.1093/bioinformatics/btx078. Erratum in: Bioinformatics. 2017 Sep 1;33(17 ):2789.

14.

A Novel Murine GITR Ligand Fusion Protein Induces Antitumor Activity as a Monotherapy That Is Further Enhanced in Combination with an OX40 Agonist.

Leyland R, Watkins A, Mulgrew KA, Holoweckyj N, Bamber L, Tigue NJ, Offer E, Andrews J, Yan L, Mullins S, Oberst MD, Coates Ulrichsen J, Leinster DA, McGlinchey K, Young L, Morrow M, Hammond SA, Mallinder P, Herath A, Leow CC, Wilkinson RW, Stewart R.

Clin Cancer Res. 2017 Jul 1;23(13):3416-3427. doi: 10.1158/1078-0432.CCR-16-2000. Epub 2017 Jan 9.

15.

Targeting CD73 in the tumor microenvironment with MEDI9447.

Hay CM, Sult E, Huang Q, Mulgrew K, Fuhrmann SR, McGlinchey KA, Hammond SA, Rothstein R, Rios-Doria J, Poon E, Holoweckyj N, Durham NM, Leow CC, Diedrich G, Damschroder M, Herbst R, Hollingsworth RE, Sachsenmeier KF.

Oncoimmunology. 2016 Jul 11;5(8):e1208875. doi: 10.1080/2162402X.2016.1208875. eCollection 2016 Aug.

16.

The Human Vaccines Project: A roadmap for cancer vaccine development.

Romero P, Banchereau J, Bhardwaj N, Cockett M, Disis ML, Dranoff G, Gilboa E, Hammond SA, Hershberg R, Korman AJ, Kvistborg P, Melief C, Mellman I, Palucka AK, Redchenko I, Robins H, Sallusto F, Schenkelberg T, Schoenberger S, Sosman J, Türeci Ö, Van den Eynde B, Koff W, Coukos G.

Sci Transl Med. 2016 Apr 13;8(334):334ps9. doi: 10.1126/scitranslmed.aaf0685. Review.

PMID:
27075624
17.

Environmental influences on the epigenomes of herpetofauna and fish.

Hammond SA, Nelson CJ, Helbing CC.

Biochem Cell Biol. 2016 Apr;94(2):95-100. doi: 10.1139/bcb-2015-0111. Epub 2015 Nov 10. Review.

PMID:
26794843
18.

A high density of tertiary lymphoid structure B cells in lung tumors is associated with increased CD4+ T cell receptor repertoire clonality.

Zhu W, Germain C, Liu Z, Sebastian Y, Devi P, Knockaert S, Brohawn P, Lehmann K, Damotte D, Validire P, Yao Y, Valge-Archer V, Hammond SA, Dieu-Nosjean MC, Higgs BW.

Oncoimmunology. 2015 Jun 1;4(12):e1051922. eCollection 2015 Dec.

19.

De novo Transcriptome Assemblies of Rana (Lithobates) catesbeiana and Xenopus laevis Tadpole Livers for Comparative Genomics without Reference Genomes.

Birol I, Behsaz B, Hammond SA, Kucuk E, Veldhoen N, Helbing CC.

PLoS One. 2015 Jun 29;10(6):e0130720. doi: 10.1371/journal.pone.0130720. eCollection 2015.

20.

Identification and Characterization of MEDI4736, an Antagonistic Anti-PD-L1 Monoclonal Antibody.

Stewart R, Morrow M, Hammond SA, Mulgrew K, Marcus D, Poon E, Watkins A, Mullins S, Chodorge M, Andrews J, Bannister D, Dick E, Crawford N, Parmentier J, Alimzhanov M, Babcook JS, Foltz IN, Buchanan A, Bedian V, Wilkinson RW, McCourt M.

Cancer Immunol Res. 2015 Sep;3(9):1052-62. doi: 10.1158/2326-6066.CIR-14-0191. Epub 2015 May 5.

21.

CEA/CD3-bispecific T cell-engaging (BiTE) antibody-mediated T lymphocyte cytotoxicity maximized by inhibition of both PD1 and PD-L1.

Osada T, Patel SP, Hammond SA, Osada K, Morse MA, Lyerly HK.

Cancer Immunol Immunother. 2015 Jun;64(6):677-88. doi: 10.1007/s00262-015-1671-y. Epub 2015 Mar 6.

PMID:
25742933
22.

Influence of temperature on thyroid hormone signaling and endocrine disruptor action in Rana (Lithobates) catesbeiana tadpoles.

Hammond SA, Veldhoen N, Helbing CC.

Gen Comp Endocrinol. 2015 Aug 1;219:6-15. doi: 10.1016/j.ygcen.2014.12.001. Epub 2015 Jan 9.

PMID:
25583582
23.

CEA/CD3 bispecific antibody MEDI-565/AMG 211 activation of T cells and subsequent killing of human tumors is independent of mutations commonly found in colorectal adenocarcinomas.

Oberst MD, Fuhrmann S, Mulgrew K, Amann M, Cheng L, Lutterbuese P, Richman L, Coats S, Baeuerle PA, Hammond SA.

MAbs. 2014;6(6):1571-84. doi: 10.4161/19420862.2014.975660.

24.

Tertiary lymphoid structures in human lung cancers, a new driver of antitumor immune responses.

Goc J, Fridman WH, Hammond SA, Sautès-Fridman C, Dieu-Nosjean MC.

Oncoimmunology. 2014 May 29;3:e28976. eCollection 2014.

25.

The immune microenvironment: a major player in human cancers.

Fridman WH, Remark R, Goc J, Giraldo NA, Becht E, Hammond SA, Damotte D, Dieu-Nosjean MC, Sautès-Fridman C.

Int Arch Allergy Immunol. 2014;164(1):13-26. doi: 10.1159/000362332. Epub 2014 May 13. Review.

PMID:
24852691
26.

Dendritic cells in tumor-associated tertiary lymphoid structures signal a Th1 cytotoxic immune contexture and license the positive prognostic value of infiltrating CD8+ T cells.

Goc J, Germain C, Vo-Bourgais TK, Lupo A, Klein C, Knockaert S, de Chaisemartin L, Ouakrim H, Becht E, Alifano M, Validire P, Remark R, Hammond SA, Cremer I, Damotte D, Fridman WH, Sautès-Fridman C, Dieu-Nosjean MC.

Cancer Res. 2014 Feb 1;74(3):705-15. doi: 10.1158/0008-5472.CAN-13-1342. Epub 2013 Dec 23.

27.

Evaluation of the effects of titanium dioxide nanoparticles on cultured Rana catesbeiana tailfin tissue.

Hammond SA, Carew AC, Helbing CC.

Front Genet. 2013 Nov 21;4:251. doi: 10.3389/fgene.2013.00251. eCollection 2013.

28.

Characterization of gene expression endpoints during postembryonic development of the northern green frog (Rana clamitans melanota).

Hammond SA, Veldhoen N, Kobylarz M, Webber NR, Jordan J, Rehaume V, Boone MD, Helbing CC.

Zoolog Sci. 2013 May;30(5):392-401. doi: 10.2108/zsj.30.392.

PMID:
23647014
29.

Specific time of exposure during tadpole development influences biological effects of the insecticide carbaryl in green frogs (Lithobates clamitans).

Boone MD, Hammond SA, Veldhoen N, Youngquist M, Helbing CC.

Aquat Toxicol. 2013 Apr 15;130-131:139-48. doi: 10.1016/j.aquatox.2012.12.022. Epub 2013 Jan 8.

PMID:
23399446
30.

The CEA/CD3-bispecific antibody MEDI-565 (MT111) binds a nonlinear epitope in the full-length but not a short splice variant of CEA.

Peng L, Oberst MD, Huang J, Brohawn P, Morehouse C, Lekstrom K, Baeuerle PA, Wu H, Yao Y, Coats SR, Dall'Acqua W, Damschroder M, Hammond SA.

PLoS One. 2012;7(5):e36412. doi: 10.1371/journal.pone.0036412. Epub 2012 May 4.

31.

Phenylalanine induces Burkholderia cenocepacia phenylacetic acid catabolism through degradation to phenylacetyl-CoA in synthetic cystic fibrosis sputum medium.

Yudistira H, McClarty L, Bloodworth RA, Hammond SA, Butcher H, Mark BL, Cardona ST.

Microb Pathog. 2011 Sep;51(3):186-93. doi: 10.1016/j.micpath.2011.04.002. Epub 2011 Apr 13.

PMID:
21511027
32.

Potent control of tumor growth by CEA/CD3-bispecific single-chain antibody constructs that are not competitively inhibited by soluble CEA.

Lutterbuese R, Raum T, Kischel R, Lutterbuese P, Schlereth B, Schaller E, Mangold S, Rau D, Meier P, Kiener PA, Mulgrew K, Oberst MD, Hammond SA, Baeuerle PA, Kufer P.

J Immunother. 2009 May;32(4):341-52. doi: 10.1097/CJI.0b013e31819b7c70.

PMID:
19342971
33.

Strictly target cell-dependent activation of T cells by bispecific single-chain antibody constructs of the BiTE class.

Brischwein K, Parr L, Pflanz S, Volkland J, Lumsden J, Klinger M, Locher M, Hammond SA, Kiener P, Kufer P, Schlereth B, Baeuerle PA.

J Immunother. 2007 Nov-Dec;30(8):798-807.

PMID:
18049331
34.

Selective targeting and potent control of tumor growth using an EphA2/CD3-Bispecific single-chain antibody construct.

Hammond SA, Lutterbuese R, Roff S, Lutterbuese P, Schlereth B, Bruckheimer E, Kinch MS, Coats S, Baeuerle PA, Kufer P, Kiener PA.

Cancer Res. 2007 Apr 15;67(8):3927-35.

35.

Immunostimulant patch enhances immune responses to influenza virus vaccine in aged mice.

Guebre-Xabier M, Hammond SA, Ellingsworth LR, Glenn GM.

J Virol. 2004 Jul;78(14):7610-8.

36.

Transcutaneous immunization induces mucosal CTLs and protective immunity by migration of primed skin dendritic cells.

Belyakov IM, Hammond SA, Ahlers JD, Glenn GM, Berzofsky JA.

J Clin Invest. 2004 Apr;113(7):998-1007.

37.

Transcutaneous immunization and immunostimulant strategies.

Glenn GM, Kenney RT, Hammond SA, Ellingsworth LR.

Immunol Allergy Clin North Am. 2003 Nov;23(4):787-813. Review.

PMID:
14753392
38.

Transcutaneous immunization and immunostimulant strategies: capitalizing on the immunocompetence of the skin.

Glenn GM, Kenney RT, Ellingsworth LR, Frech SA, Hammond SA, Zoeteweij JP.

Expert Rev Vaccines. 2003 Apr;2(2):253-67. Review.

PMID:
12899576
39.
40.
41.

Transcutaneous immunization using colonization factor and heat-labile enterotoxin induces correlates of protective immunity for enterotoxigenic Escherichia coli.

Yu J, Cassels F, Scharton-Kersten T, Hammond SA, Hartman A, Angov E, Corthésy B, Alving C, Glenn G.

Infect Immun. 2002 Mar;70(3):1056-68.

42.

Transcutaneous immunization: an emerging route of immunization and potent immunostimulation strategy.

Hammond SA, Guebre-Xabier M, Yu J, Glenn GM.

Crit Rev Ther Drug Carrier Syst. 2001;18(5):503-26. Review.

PMID:
11763499
43.

Transcutaneous immunization: T cell responses and boosting of existing immunity.

Hammond SA, Walwender D, Alving CR, Glenn GM.

Vaccine. 2001 Mar 21;19(17-19):2701-7.

PMID:
11257412
44.

Transcutaneous immunization of domestic animals: opportunities and challenges.

Hammond SA, Tsonis C, Sellins K, Rushlow K, Scharton-Kersten T, Colditz I, Glenn GM.

Adv Drug Deliv Rev. 2000 Sep 15;43(1):45-55. Review.

PMID:
10967220
45.

Immune responses and viral replication in long-term inapparent carrier ponies inoculated with equine infectious anemia virus.

Hammond SA, Li F, McKeon BM Sr, Cook SJ, Issel CJ, Montelaro RC.

J Virol. 2000 Jul;74(13):5968-81.

46.

Functional characterization of equine dendritic cells propagated ex vivo using recombinant human GM-CSF and recombinant equine IL-4.

Hammond SA, Horohov D, Montelaro RC.

Vet Immunol Immunopathol. 1999 Nov 30;71(3-4):197-214.

PMID:
10587301
47.
48.
49.

Maturation of immune responses to lentivirus infection: implications for AIDS vaccine development.

Montelaro RC, Cole KS, Hammond SA.

AIDS Res Hum Retroviruses. 1998 Oct;14 Suppl 3:S255-9. Review.

PMID:
9814952
50.

General method for the detection and in vitro expansion of equine cytolytic T lymphocytes.

Hammond SA, Issel CJ, Montelaro RC.

J Immunol Methods. 1998 Apr 1;213(1):73-85.

PMID:
9671126

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