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Items: 1 to 50 of 835

1.

Omega-3 PUFA attenuate mice myocardial infarction injury by emerging a protective eicosanoid pattern.

Fang X, Cai W, Cheng Q, Ai D, Wang X, Hammock BD, Zhu Y, Zhang X.

Prostaglandins Other Lipid Mediat. 2018 Sep 14. pii: S1098-8823(18)30050-9. doi: 10.1016/j.prostaglandins.2018.09.002. [Epub ahead of print] Review.

PMID:
30223037
2.

Development of a Nanobody-AviTag Fusion Protein and Its Application in a Streptavidin-Biotin-Amplified Enzyme-Linked Immunosorbent Assay for Ochratoxin A in Cereal.

Sun Z, Lv J, Liu X, Tang Z, Wang X, Xu Y, Hammock BD.

Anal Chem. 2018 Sep 4;90(17):10628-10634. doi: 10.1021/acs.analchem.8b03085. Epub 2018 Aug 22.

PMID:
30092629
3.

Strong and oriented conjugation of nanobodies onto magnetosomes for the development of a rapid immunomagnetic assay for the environmental detection of tetrabromobisphenol-A.

He J, Tian J, Xu J, Wang K, Li J, Gee SJ, Hammock BD, Li QX, Xu T.

Anal Bioanal Chem. 2018 Oct;410(25):6633-6642. doi: 10.1007/s00216-018-1270-9. Epub 2018 Aug 1.

PMID:
30066195
4.

Soluble epoxide hydrolase inhibitor promotes immunomodulation to inhibit bone resorption.

Napimoga MH, Rocha EP, Trindade-da-Silva CA, Demasi APD, Martinez EF, Macedo CG, Abdalla HB, Bettaieb A, Haj FG, Clemente-Napimoga JT, Inceoglu B, Hammock BD.

J Periodontal Res. 2018 May 31. doi: 10.1111/jre.12559. [Epub ahead of print]

PMID:
29851077
5.

Celecoxib Does Not Protect against Fibrosis and Inflammation in a Carbon Tetrachloride-Induced Model of Liver Injury.

Harris TR, Kodani S, Rand AA, Yang J, Imai DM, Hwang SH, Hammock BD.

Mol Pharmacol. 2018 Aug;94(2):834-841. doi: 10.1124/mol.118.111831. Epub 2018 May 29.

PMID:
29844231
6.

Adamantyl thioureas as soluble epoxide hydrolase inhibitors.

Burmistrov V, Morisseau C, Pitushkin D, Karlov D, Fayzullin RR, Butov GM, Hammock BD.

Bioorg Med Chem Lett. 2018 Jul 15;28(13):2302-2313. doi: 10.1016/j.bmcl.2018.05.024. Epub 2018 May 23.

PMID:
29803731
7.

An inhibitor of soluble epoxide hydrolase ameliorates diabetes-induced learning and memory impairment in rats.

Minaz N, Razdan R, Hammock BD, Goswami SK.

Prostaglandins Other Lipid Mediat. 2018 May;136:84-89. doi: 10.1016/j.prostaglandins.2018.05.004. Epub 2018 May 8.

PMID:
29751149
8.

Soluble epoxide hydrolase plays a key role in the pathogenesis of Parkinson's disease.

Ren Q, Ma M, Yang J, Nonaka R, Yamaguchi A, Ishikawa KI, Kobayashi K, Murayama S, Hwang SH, Saiki S, Akamatsu W, Hattori N, Hammock BD, Hashimoto K.

Proc Natl Acad Sci U S A. 2018 Jun 19;115(25):E5815-E5823. doi: 10.1073/pnas.1802179115. Epub 2018 May 7.

PMID:
29735655
9.

Lipidomic profiling reveals soluble epoxide hydrolase as a therapeutic target of obesity-induced colonic inflammation.

Wang W, Yang J, Zhang J, Wang Y, Hwang SH, Qi W, Wan D, Kim D, Sun J, Sanidad KZ, Yang H, Park Y, Liu JY, Zhao X, Zheng X, Liu Z, Hammock BD, Zhang G.

Proc Natl Acad Sci U S A. 2018 May 15;115(20):5283-5288. doi: 10.1073/pnas.1721711115. Epub 2018 May 1.

PMID:
29717038
10.

Correction to Optimized Inhibitors of Soluble Epoxide Hydrolase Improve in Vitro Target Residence Time and in Vivo Efficacy.

Lee KSS, Liu JY, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P, Ulu A, Mate CA, Nguyen LV, Hwang SH, Edin ML, Mara AA, Wulff H, Newcomer ME, Zeldin DC, Hammock BD.

J Med Chem. 2018 May 10;61(9):4271. doi: 10.1021/acs.jmedchem.8b00582. Epub 2018 Apr 27. No abstract available.

11.

Celecoxib use and circulating oxylipins in a colon polyp prevention trial.

Martinez JA, Yang J, Wertheim BC, Roe DJ, Schriewer A, Lance P, Alberts DS, Hammock BD, Thompson PA.

PLoS One. 2018 Apr 26;13(4):e0196398. doi: 10.1371/journal.pone.0196398. eCollection 2018.

12.

Noncompetitive Homogeneous Detection of Small Molecules Using Synthetic Nanopeptamer-Based Luminescent Oxygen Channeling.

Lassabe G, Kramer K, Hammock BD, González-Sapienza G, González-Techera A.

Anal Chem. 2018 May 15;90(10):6187-6192. doi: 10.1021/acs.analchem.8b00657. Epub 2018 May 1.

PMID:
29694028
13.

Effects of triclosan in breast milk on the infant fecal microbiome.

Bever CS, Rand AA, Nording M, Taft D, Kalanetra KM, Mills DA, Breck MA, Smilowitz JT, German JB, Hammock BD.

Chemosphere. 2018 Jul;203:467-473. doi: 10.1016/j.chemosphere.2018.03.186. Epub 2018 Mar 28.

PMID:
29635158
14.

Biotinylated single-chain variable fragment-based enzyme-linked immunosorbent assay for glycocholic acid.

Cui X, Vasylieva N, Shen D, Barnych B, Yang J, He Q, Jiang Z, Zhao S, Hammock BD.

Analyst. 2018 Apr 30;143(9):2057-2065. doi: 10.1039/c7an02024d.

PMID:
29629470
15.

Orally Available Soluble Epoxide Hydrolase/Phosphodiesterase 4 Dual Inhibitor Treats Inflammatory Pain.

Blöcher R, Wagner KM, Gopireddy RR, Harris TR, Wu H, Barnych B, Hwang SH, Xiang YK, Proschak E, Morisseau C, Hammock BD.

J Med Chem. 2018 Apr 26;61(8):3541-3550. doi: 10.1021/acs.jmedchem.7b01804. Epub 2018 Apr 10.

PMID:
29614224
16.

Soluble epoxide hydrolase inhibition decreases reperfusion injury after focal cerebral ischemia.

Tu R, Armstrong J, Lee KSS, Hammock BD, Sapirstein A, Koehler RC.

Sci Rep. 2018 Mar 27;8(1):5279. doi: 10.1038/s41598-018-23504-1.

17.

Two pharmacological epoxyeicosatrienoic acid-enhancing therapies are effectively antihypertensive and reduce the severity of ischemic arrhythmias in rats with angiotensin II-dependent hypertension.

Červenka L, Husková Z, Kopkan L, Kikerlová S, Sedláková L, Vaňourková Z, Alánová P, Kolář F, Hammock BD, Hwang SH, Imig JD, Falck JR, Sadowski J, Kompanowska-Jezierska E, Neckář J.

J Hypertens. 2018 Jun;36(6):1326-1341. doi: 10.1097/HJH.0000000000001708.

PMID:
29570510
18.

Indomethacin Enhances Brown Fat Activity.

Hao L, Kearns J, Scott S, Wu D, Kodani SD, Morisseau C, Hammock BD, Sun X, Zhao L, Wang S.

J Pharmacol Exp Ther. 2018 Jun;365(3):467-475. doi: 10.1124/jpet.117.246256. Epub 2018 Mar 22.

PMID:
29567865
19.

Novel piperidine-derived amide sEH inhibitors as mediators of lipid metabolism with improved stability.

Pecic S, Zeki AA, Xu X, Jin GY, Zhang S, Kodani S, Halim M, Morisseau C, Hammock BD, Deng SX.

Prostaglandins Other Lipid Mediat. 2018 May;136:90-95. doi: 10.1016/j.prostaglandins.2018.02.004. Epub 2018 Mar 20.

PMID:
29567338
20.

Combined Inhibition of Soluble Epoxide Hydrolase and Renin-Angiotensin System Exhibits Superior Renoprotection to Renin-Angiotensin System Blockade in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats with Established Chronic Kidney Disease.

Čertíková Chábová V, Kujal P, Škaroupková P, Varňourková Z, Vacková Š, Husková Z, Kikerlová S, Sadowski J, Kompanowska-Jezierska E, Baranowska I, Hwang SH, Hammock BD, Imig JD, Tesař V, Červenka L.

Kidney Blood Press Res. 2018;43(2):329-349. doi: 10.1159/000487902. Epub 2018 Mar 6.

21.

Effect of angiotensin-converting enzyme blockade, alone or combined with blockade of soluble epoxide hydrolase, on the course of congestive heart failure and occurrence of renal dysfunction in Ren-2 transgenic hypertensive rats with aorto-caval fistula.

Kala P, Sedláková L, Škaroupková P, Kopkan L, Vaňourková Z, Táborský M, Nishiyama A, Hwang SH, Hammock BD, Sadowski J, Melenovský V, Imig JD, Červenka L.

Physiol Res. 2018 Jul 17;67(3):401-415. Epub 2018 Mar 12.

22.

Induction of Amyloid-β42 Production by Fipronil and Other Pyrazole Insecticides.

Cam M, Durieu E, Bodin M, Manousopoulou A, Koslowski S, Vasylieva N, Barnych B, Hammock BD, Bohl B, Koch P, Omori C, Yamamoto K, Hata S, Suzuki T, Karg F, Gizzi P, Haber VE, Bencetic Mihaljevic V, Tavcar B, Portelius E, Pannee J, Blennow K, Zetterberg H, Garbis SD, Auvray P, Gerber H, Fraering J, Fraering PC, Meijer L.

J Alzheimers Dis. 2018;62(4):1663-1681. doi: 10.3233/JAD-170875.

PMID:
29504531
23.

Catalytic activities of mammalian epoxide hydrolases with cis and trans fatty acid epoxides relevant to skin barrier function.

Yamanashi H, Boeglin WE, Morisseau C, Davis RW, Sulikowski GA, Hammock BD, Brash AR.

J Lipid Res. 2018 Apr;59(4):684-695. doi: 10.1194/jlr.M082701. Epub 2018 Feb 19.

PMID:
29459481
24.

Metabolic/inflammatory/vascular comorbidity in psychiatric disorders; soluble epoxide hydrolase (sEH) as a possible new target.

Swardfager W, Hennebelle M, Yu D, Hammock BD, Levitt AJ, Hashimoto K, Taha AY.

Neurosci Biobehav Rev. 2018 Apr;87:56-66. doi: 10.1016/j.neubiorev.2018.01.010. Epub 2018 Feb 2. Review.

PMID:
29407524
25.

Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase.

Kodani SD, Bhakta S, Hwang SH, Pakhomova S, Newcomer ME, Morisseau C, Hammock BD.

Bioorg Med Chem Lett. 2018 Feb 15;28(4):762-768. doi: 10.1016/j.bmcl.2018.01.003. Epub 2018 Jan 4.

PMID:
29366648
26.

LC-MS/MS Analysis of the Epoxides and Diols Derived from the Endocannabinoid Arachidonoyl Ethanolamide.

Rand AA, Helmer PO, Inceoglu B, Hammock BD, Morisseau C.

Methods Mol Biol. 2018;1730:123-133. doi: 10.1007/978-1-4939-7592-1_10.

PMID:
29363071
27.

Inhibition of soluble epoxide hydrolase attenuates eosinophil recruitment and food allergen-induced gastrointestinal inflammation.

Bastan I, Ge XN, Dileepan M, Greenberg YG, Guedes AG, Hwang SH, Hammock BD, Washabau RJ, Rao SP, Sriramarao P.

J Leukoc Biol. 2018 Jul;104(1):109-122. doi: 10.1002/JLB.3MA1017-423R. Epub 2018 Jan 17.

PMID:
29345370
28.

Effects of adamantane alterations on soluble epoxide hydrolase inhibition potency, physical properties and metabolic stability.

Burmistrov V, Morisseau C, Harris TR, Butov G, Hammock BD.

Bioorg Chem. 2018 Feb;76:510-527. doi: 10.1016/j.bioorg.2017.12.024. Epub 2017 Dec 30.

PMID:
29310082
29.

Estrogen-dependent epigenetic regulation of soluble epoxide hydrolase via DNA methylation.

Yang YM, Sun D, Kandhi S, Froogh G, Zhuge J, Huang W, Hammock BD, Huang A.

Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):613-618. doi: 10.1073/pnas.1716016115. Epub 2018 Jan 2.

30.

Phage-Mediated Competitive Chemiluminescent Immunoassay for Detecting Cry1Ab Toxin by Using an Anti-Idiotypic Camel Nanobody.

Qiu Y, Li P, Dong S, Zhang X, Yang Q, Wang Y, Ge J, Hammock BD, Zhang C, Liu X.

J Agric Food Chem. 2018 Jan 31;66(4):950-956. doi: 10.1021/acs.jafc.7b04923. Epub 2018 Jan 22.

PMID:
29293334
31.

COX-2/sEH Dual Inhibitor PTUPB Potentiates the Antitumor Efficacy of Cisplatin.

Wang F, Zhang H, Ma AH, Yu W, Zimmermann M, Yang J, Hwang SH, Zhu D, Lin TY, Malfatti M, Turteltaub KW, Henderson PT, Airhart S, Hammock BD, Yuan J, de Vere White RW, Pan CX.

Mol Cancer Ther. 2018 Feb;17(2):474-483. doi: 10.1158/1535-7163.MCT-16-0818. Epub 2017 Dec 28.

PMID:
29284644
32.

Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy.

Hu J, Dziumbla S, Lin J, Bibli SI, Zukunft S, de Mos J, Awwad K, Frömel T, Jungmann A, Devraj K, Cheng Z, Wang L, Fauser S, Eberhart CG, Sodhi A, Hammock BD, Liebner S, Müller OJ, Glaubitz C, Hammes HP, Popp R, Fleming I.

Nature. 2017 Dec 14;552(7684):248-252. doi: 10.1038/nature25013. Epub 2017 Dec 6.

PMID:
29211719
33.

Evaluation of antiparkinson activity of PTUPB by measuring dopamine and its metabolites in Drosophila melanogaster: LC-MS/MS method development.

Lakkappa N, Krishnamurthy PT, Yamjala K, Hwang SH, Hammock BD, Babu B.

J Pharm Biomed Anal. 2018 Feb 5;149:457-464. doi: 10.1016/j.jpba.2017.11.043. Epub 2017 Nov 16.

PMID:
29169114
34.

COX-2/sEH dual inhibitor PTUPB suppresses glioblastoma growth by targeting epidermal growth factor receptor and hyaluronan mediated motility receptor.

Li J, Zhou Y, Wang H, Gao Y, Li L, Hwang SH, Ji X, Hammock BD.

Oncotarget. 2017 Sep 15;8(50):87353-87363. doi: 10.18632/oncotarget.20928. eCollection 2017 Oct 20.

35.

Epoxide metabolites of arachidonate and docosahexaenoate function conversely in acute kidney injury involved in GSK3β signaling.

Deng BQ, Luo Y, Kang X, Li CB, Morisseau C, Yang J, Lee KSS, Huang J, Hu DY, Wu MY, Peng A, Hammock BD, Liu JY.

Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12608-12613. doi: 10.1073/pnas.1705615114. Epub 2017 Nov 6.

36.

Pharmacokinetics and antinociceptive effects of the soluble epoxide hydrolase inhibitor t-TUCB in horses with experimentally induced radiocarpal synovitis.

Guedes AGP, Aristizabal F, Sole A, Adedeji A, Brosnan R, Knych H, Yang J, Hwang SH, Morisseau C, Hammock BD.

J Vet Pharmacol Ther. 2018 Apr;41(2):230-238. doi: 10.1111/jvp.12463. Epub 2017 Oct 25.

PMID:
29067696
37.

Omega-6 and omega-3 oxylipins are implicated in soybean oil-induced obesity in mice.

Deol P, Fahrmann J, Yang J, Evans JR, Rizo A, Grapov D, Salemi M, Wanichthanarak K, Fiehn O, Phinney B, Hammock BD, Sladek FM.

Sci Rep. 2017 Oct 2;7(1):12488. doi: 10.1038/s41598-017-12624-9.

38.

Development of an Indirect Competitive Enzyme-Linked Immunosorbent Assay for Glycocholic Acid Based on Chicken Single-Chain Variable Fragment Antibodies.

Cui X, Vasylieva N, Wu P, Barnych B, Yang J, Shen D, He Q, Gee SJ, Zhao S, Hammock BD.

Anal Chem. 2017 Oct 17;89(20):11091-11097. doi: 10.1021/acs.analchem.7b03190. Epub 2017 Oct 4.

PMID:
28942640
39.

Postprandial effect to decrease soluble epoxide hydrolase activity: roles of insulin and gut microbiota.

Yang J, Oh YT, Wan D, Watanabe RM, Hammock BD, Youn JH.

J Nutr Biochem. 2017 Nov;49:8-14. doi: 10.1016/j.jnutbio.2017.07.006. Epub 2017 Jul 21.

PMID:
28863368
40.

Modulation of mitochondrial dysfunction and endoplasmic reticulum stress are key mechanisms for the wide-ranging actions of epoxy fatty acids and soluble epoxide hydrolase inhibitors.

Inceoglu B, Bettaieb A, Haj FG, Gomes AV, Hammock BD.

Prostaglandins Other Lipid Mediat. 2017 Nov;133:68-78. doi: 10.1016/j.prostaglandins.2017.08.003. Epub 2017 Aug 25. Review.

PMID:
28847566
41.

Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization.

Hasegawa E, Inafuku S, Mulki L, Okunuki Y, Yanai R, Smith KE, Kim CB, Klokman G, Bielenberg DR, Puli N, Falck JR, Husain D, Miller JW, Edin ML, Zeldin DC, Lee KSS, Hammock BD, Schunck WH, Connor KM.

Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):E7545-E7553. doi: 10.1073/pnas.1620898114. Epub 2017 Aug 21.

42.

Soluble epoxide hydrolase in podocytes is a significant contributor to renal function under hyperglycemia.

Bettaieb A, Koike S, Hsu MF, Ito Y, Chahed S, Bachaalany S, Gruzdev A, Calvo-Rubio M, Lee KSS, Inceoglu B, Imig JD, Villalba JM, Zeldin DC, Hammock BD, Haj FG.

Biochim Biophys Acta Gen Subj. 2017 Nov;1861(11 Pt A):2758-2765. doi: 10.1016/j.bbagen.2017.07.021. Epub 2017 Jul 27.

PMID:
28757338
43.

Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission.

Hennebelle M, Zhang Z, Metherel AH, Kitson AP, Otoki Y, Richardson CE, Yang J, Lee KSS, Hammock BD, Zhang L, Bazinet RP, Taha AY.

Sci Rep. 2017 Jun 28;7(1):4342. doi: 10.1038/s41598-017-02914-7.

44.

Shexiang Baoxin pills promotes angiogenesis in myocardial infarction rats via up-regulation of 20-HETE-mediated endothelial progenitor cells mobilization.

Huang F, Liu Y, Yang X, Che D, Qiu K, Hammock BD, Wang J, Wang MH, Chen J, Huang H.

Atherosclerosis. 2017 Aug;263:184-191. doi: 10.1016/j.atherosclerosis.2017.06.012. Epub 2017 Jun 7.

45.

Soluble epoxide hydrolase as a therapeutic target for pain, inflammatory and neurodegenerative diseases.

Wagner KM, McReynolds CB, Schmidt WK, Hammock BD.

Pharmacol Ther. 2017 Dec;180:62-76. doi: 10.1016/j.pharmthera.2017.06.006. Epub 2017 Jun 19. Review.

PMID:
28642117
46.

Lipoxygenase Activity Accelerates Programmed Spore Germination in Aspergillus fumigatus.

Fischer GJ, Bacon W, Yang J, Palmer JM, Dagenais T, Hammock BD, Keller NP.

Front Microbiol. 2017 May 9;8:831. doi: 10.3389/fmicb.2017.00831. eCollection 2017.

47.

Pharmacological inhibition of soluble epoxide hydrolase or genetic deletion reduces diclofenac-induced gastric ulcers.

Goswami SK, Rand AA, Wan D, Yang J, Inceoglu B, Thomas M, Morisseau C, Yang GY, Hammock BD.

Life Sci. 2017 Jul 1;180:114-122. doi: 10.1016/j.lfs.2017.05.018. Epub 2017 May 15.

48.

Podocyte-specific soluble epoxide hydrolase deficiency in mice attenuates acute kidney injury.

Bettaieb A, Koike S, Chahed S, Zhao Y, Bachaalany S, Hashoush N, Graham J, Fatima H, Havel PJ, Gruzdev A, Zeldin DC, Hammock BD, Haj FG.

FEBS J. 2017 Jul;284(13):1970-1986. doi: 10.1111/febs.14100. Epub 2017 May 29. Erratum in: FEBS J. 2018 Feb;285(3):629-632.

49.

Reduced carboxylesterase 1 is associated with endothelial injury in methamphetamine-induced pulmonary arterial hypertension.

Orcholski ME, Khurshudyan A, Shamskhou EA, Yuan K, Chen IY, Kodani SD, Morisseau C, Hammock BD, Hong EM, Alexandrova L, Alastalo TP, Berry G, Zamanian RT, de Jesus Perez VA.

Am J Physiol Lung Cell Mol Physiol. 2017 Aug 1;313(2):L252-L266. doi: 10.1152/ajplung.00453.2016. Epub 2017 May 4.

50.

Occurrence of urea-based soluble epoxide hydrolase inhibitors from the plants in the order Brassicales.

Kitamura S, Morisseau C, Harris TR, Inceoglu B, Hammock BD.

PLoS One. 2017 May 4;12(5):e0176571. doi: 10.1371/journal.pone.0176571. eCollection 2017.

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