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Items: 20


Anti-tumor T-cell homeostatic activation is uncoupled from homeostatic inhibition by checkpoint blockade.

Marshall N, Hutchinson K, Marron TU, Aleynick M, Hammerich L, Upadhyay R, Svensson-Arvelund J, Brown BD, Merad M, Brody JD.

Cancer Discov. 2019 Aug 2. pii: CD-19-0391. doi: 10.1158/2159-8290.CD-19-0391. [Epub ahead of print]


Systemic clinical tumor regressions and potentiation of PD1 blockade with in situ vaccination.

Hammerich L, Marron TU, Upadhyay R, Svensson-Arvelund J, Dhainaut M, Hussein S, Zhan Y, Ostrowski D, Yellin M, Marsh H, Salazar AM, Rahman AH, Brown BD, Merad M, Brody JD.

Nat Med. 2019 May;25(5):814-824. doi: 10.1038/s41591-019-0410-x. Epub 2019 Apr 8.


Targeting CCl4 -induced liver fibrosis by RNA interference-mediated inhibition of cyclin E1 in mice.

Bangen JM, Hammerich L, Sonntag R, Baues M, Haas U, Lambertz D, Longerich T, Lammers T, Tacke F, Trautwein C, Liedtke C.

Hepatology. 2017 Oct;66(4):1242-1257. doi: 10.1002/hep.29275. Epub 2017 Aug 26.


In situ vaccination for the treatment of cancer.

Hammerich L, Bhardwaj N, Kohrt HE, Brody JD.

Immunotherapy. 2016;8(3):315-30. doi: 10.2217/imt.15.120. Epub 2016 Feb 9. Review.


In situ vaccination: Cancer immunotherapy both personalized and off-the-shelf.

Hammerich L, Binder A, Brody JD.

Mol Oncol. 2015 Dec;9(10):1966-81. doi: 10.1016/j.molonc.2015.10.016. Epub 2015 Nov 10. Review.


Emerging roles of myeloid derived suppressor cells in hepatic inflammation and fibrosis.

Hammerich L, Tacke F.

World J Gastrointest Pathophysiol. 2015 Aug 15;6(3):43-50. doi: 10.4291/wjgp.v6.i3.43.


Lymphoma: immune evasion strategies.

Upadhyay R, Hammerich L, Peng P, Brown B, Merad M, Brody JD.

Cancers (Basel). 2015 Apr 30;7(2):736-62. doi: 10.3390/cancers7020736. Review.


Cyclic adenosine monophosphate-responsive element modulator alpha overexpression impairs function of hepatic myeloid-derived suppressor cells and aggravates immune-mediated hepatitis in mice.

Hammerich L, Warzecha KT, Stefkova M, Bartneck M, Ohl K, Gassler N, Luedde T, Trautwein C, Tenbrock K, Tacke F.

Hepatology. 2015 Mar;61(3):990-1002. doi: 10.1002/hep.27571. Epub 2015 Jan 30.


Interleukins in chronic liver disease: lessons learned from experimental mouse models.

Hammerich L, Tacke F.

Clin Exp Gastroenterol. 2014 Sep 1;7:297-306. doi: 10.2147/CEG.S43737. eCollection 2014. Review.


Role of gamma-delta T cells in liver inflammation and fibrosis.

Hammerich L, Tacke F.

World J Gastrointest Pathophysiol. 2014 May 15;5(2):107-13. doi: 10.4291/wjgp.v5.i2.107. Review.


Eat more carrots? Dampening cell death in ethanol-induced liver fibrosis by β-carotene.

Hammerich L, Tacke F.

Hepatobiliary Surg Nutr. 2013 Oct;2(5):248-51. doi: 10.3978/j.issn.2304-3881.2013.10.03.


Origin of regenerating tubular cells after acute kidney injury.

Berger K, Bangen JM, Hammerich L, Liedtke C, Floege J, Smeets B, Moeller MJ.

Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1533-8. doi: 10.1073/pnas.1316177111. Epub 2014 Jan 13.


RIP3 inhibits inflammatory hepatocarcinogenesis but promotes cholestasis by controlling caspase-8- and JNK-dependent compensatory cell proliferation.

Vucur M, Reisinger F, Gautheron J, Janssen J, Roderburg C, Cardenas DV, Kreggenwinkel K, Koppe C, Hammerich L, Hakem R, Unger K, Weber A, Gassler N, Luedde M, Frey N, Neumann UP, Tacke F, Trautwein C, Heikenwalder M, Luedde T.

Cell Rep. 2013 Aug 29;4(4):776-90. doi: 10.1016/j.celrep.2013.07.035. Epub 2013 Aug 22.


Chemokine receptor CCR6-dependent accumulation of γδ T cells in injured liver restricts hepatic inflammation and fibrosis.

Hammerich L, Bangen JM, Govaere O, Zimmermann HW, Gassler N, Huss S, Liedtke C, Prinz I, Lira SA, Luedde T, Roskams T, Trautwein C, Heymann F, Tacke F.

Hepatology. 2014 Feb;59(2):630-42. doi: 10.1002/hep.26697. Epub 2013 Dec 23.


Chemokine receptor CXCR6-dependent hepatic NK T Cell accumulation promotes inflammation and liver fibrosis.

Wehr A, Baeck C, Heymann F, Niemietz PM, Hammerich L, Martin C, Zimmermann HW, Pack O, Gassler N, Hittatiya K, Ludwig A, Luedde T, Trautwein C, Tacke F.

J Immunol. 2013 May 15;190(10):5226-36. doi: 10.4049/jimmunol.1202909. Epub 2013 Apr 17.


Met-CCL5 modifies monocyte subpopulations during liver fibrosis regression.

Stock MK, Hammerich L, do O NT, Berres ML, Alsamman M, Heinrichs D, Nellen A, Trautwein C, Tacke F, Wasmuth HE, Sahin H.

Int J Clin Exp Pathol. 2013;6(4):678-85. Epub 2013 Mar 15.


Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor C-C motif chemokine receptor 8 in mice.

Heymann F, Hammerich L, Storch D, Bartneck M, Huss S, Rüsseler V, Gassler N, Lira SA, Luedde T, Trautwein C, Tacke F.

Hepatology. 2012 Mar;55(3):898-909. doi: 10.1002/hep.24764. Epub 2012 Jan 13.


Role of IL-17 and Th17 cells in liver diseases.

Hammerich L, Heymann F, Tacke F.

Clin Dev Immunol. 2011;2011:345803. doi: 10.1155/2011/345803. Epub 2010 Dec 15. Review.


Kidney Dendritic Cells Become Pathogenic during Crescentic Glomerulonephritis with Proteinuria.

Hochheiser K, Engel DR, Hammerich L, Heymann F, Knolle PA, Panzer U, Kurts C.

J Am Soc Nephrol. 2011 Feb;22(2):306-16. doi: 10.1681/ASN.2010050548. Epub 2010 Dec 16.


Kidney dendritic cell activation is required for progression of renal disease in a mouse model of glomerular injury.

Heymann F, Meyer-Schwesinger C, Hamilton-Williams EE, Hammerich L, Panzer U, Kaden S, Quaggin SE, Floege J, Gröne HJ, Kurts C.

J Clin Invest. 2009 May;119(5):1286-97. doi: 10.1172/JCI38399. Epub 2009 Apr 20. Erratum in: J Clin Invest. 2009 Jul;119(7):2114.

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