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Items: 1 to 50 of 135

1.

The Structure of Melanoregulin Reveals a Role for Cholesterol Recognition in the Protein's Ability to Promote Dynein Function.

Rout AK, Wu X, Starich MR, Strub MP, Hammer JA, Tjandra N.

Structure. 2018 Aug 8. pii: S0969-2126(18)30255-7. doi: 10.1016/j.str.2018.07.009. [Epub ahead of print]

PMID:
30174147
2.

Creation of a myosin Va-TAP tagged mouse and identification of potential myosin Va-interacting proteins in the cerebellum.

Alexander CJ, Wagner W, Copeland NG, Jenkins NA, Hammer JA.

Cytoskeleton (Hoboken). 2018 Jul 6. doi: 10.1002/cm.21474. [Epub ahead of print]

PMID:
29979496
3.

Dynamic Ligand Presentation in Biomaterials.

Hammer JA, West JL.

Bioconjug Chem. 2018 Jul 18;29(7):2140-2149. doi: 10.1021/acs.bioconjchem.8b00288. Epub 2018 Jun 14.

PMID:
29791139
4.

Myosin goes for blood.

Hammer JA.

Proc Natl Acad Sci U S A. 2018 May 8;115(19):4813-4815. doi: 10.1073/pnas.1805253115. Epub 2018 Apr 24. No abstract available.

PMID:
29691320
5.

Immunology: Is Actin at the Lytic Synapse a Friend or a Foe?

Hammer JA.

Curr Biol. 2018 Feb 19;28(4):R155-R157. doi: 10.1016/j.cub.2018.01.013.

PMID:
29462581
6.

A centrosomal scaffold shows some self-control.

Varadarajan R, Hammer JA, Rusan NM.

J Biol Chem. 2017 Dec 15;292(50):20410-20411. doi: 10.1074/jbc.H117.806018. Review.

7.

Myosin-X knockout is semi-lethal and demonstrates that myosin-X functions in neural tube closure, pigmentation, hyaloid vasculature regression, and filopodia formation.

Heimsath EG Jr, Yim YI, Mustapha M, Hammer JA, Cheney RE.

Sci Rep. 2017 Dec 11;7(1):17354. doi: 10.1038/s41598-017-17638-x.

8.

Mitochondrial fission facilitates the selective mitophagy of protein aggregates.

Burman JL, Pickles S, Wang C, Sekine S, Vargas JNS, Zhang Z, Youle AM, Nezich CL, Wu X, Hammer JA, Youle RJ.

J Cell Biol. 2017 Oct 2;216(10):3231-3247. doi: 10.1083/jcb.201612106. Epub 2017 Sep 11.

9.

TGF-β1 alters esophageal epithelial barrier function by attenuation of claudin-7 in eosinophilic esophagitis.

Nguyen N, Fernando SD, Biette KA, Hammer JA, Capocelli KE, Kitzenberg DA, Glover LE, Colgan SP, Furuta GT, Masterson JC.

Mucosal Immunol. 2018 Mar;11(2):415-426. doi: 10.1038/mi.2017.72. Epub 2017 Aug 23.

10.

Contractile actomyosin arcs promote the activation of primary mouse T cells in a ligand-dependent manner.

Hong J, Murugesan S, Betzig E, Hammer JA.

PLoS One. 2017 Aug 17;12(8):e0183174. doi: 10.1371/journal.pone.0183174. eCollection 2017.

11.

Re-evaluating the roles of myosin 18Aα and F-actin in determining Golgi morphology.

Bruun K, Beach JR, Heissler SM, Remmert K, Sellers JR, Hammer JA.

Cytoskeleton (Hoboken). 2017 May;74(5):205-218. doi: 10.1002/cm.21364. Epub 2017 May 10.

PMID:
28329908
12.

Actin dynamics and competition for myosin monomer govern the sequential amplification of myosin filaments.

Beach JR, Bruun KS, Shao L, Li D, Swider Z, Remmert K, Zhang Y, Conti MA, Adelstein RS, Rusan NM, Betzig E, Hammer JA.

Nat Cell Biol. 2017 Feb;19(2):85-93. doi: 10.1038/ncb3463. Epub 2017 Jan 23.

13.

Formin-generated actomyosin arcs propel T cell receptor microcluster movement at the immune synapse.

Murugesan S, Hong J, Yi J, Li D, Beach JR, Shao L, Meinhardt J, Madison G, Wu X, Betzig E, Hammer JA.

J Cell Biol. 2016 Nov 7;215(3):383-399. Epub 2016 Oct 31.

14.

V-1 regulates capping protein activity in vivo.

Jung G, Alexander CJ, Wu XS, Piszczek G, Chen BC, Betzig E, Hammer JA.

Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6610-E6619. Epub 2016 Oct 10.

15.

Optimization of cerebellar purkinje neuron cultures and development of a plasmid-based method for purkinje neuron-specific, miRNA-mediated protein knockdown.

Alexander CJ, Hammer JA 3rd.

Methods Cell Biol. 2016;131:177-97. doi: 10.1016/bs.mcb.2015.06.004. Epub 2015 Sep 2.

PMID:
26794514
16.

ADVANCED IMAGING. Extended-resolution structured illumination imaging of endocytic and cytoskeletal dynamics.

Li D, Shao L, Chen BC, Zhang X, Zhang M, Moses B, Milkie DE, Beach JR, Hammer JA 3rd, Pasham M, Kirchhausen T, Baird MA, Davidson MW, Xu P, Betzig E.

Science. 2015 Aug 28;349(6251):aab3500. doi: 10.1126/science.aab3500.

17.

Cooperative interactions of LPPR family members in membrane localization and alteration of cellular morphology.

Yu P, Agbaegbu C, Malide DA, Wu X, Katagiri Y, Hammer JA, Geller HM.

J Cell Sci. 2015 Sep 1;128(17):3210-22. doi: 10.1242/jcs.169789. Epub 2015 Jul 16.

18.

Myosin 18A coassembles with nonmuscle myosin 2 to form mixed bipolar filaments.

Billington N, Beach JR, Heissler SM, Remmert K, Guzik-Lendrum S, Nagy A, Takagi Y, Shao L, Li D, Yang Y, Zhang Y, Barzik M, Betzig E, Hammer JA 3rd, Sellers JR.

Curr Biol. 2015 Mar 30;25(7):942-8. doi: 10.1016/j.cub.2015.02.012. Epub 2015 Mar 5.

19.

Myosin II isoform co-assembly and differential regulation in mammalian systems.

Beach JR, Hammer JA 3rd.

Exp Cell Res. 2015 May 15;334(1):2-9. doi: 10.1016/j.yexcr.2015.01.012. Epub 2015 Feb 2. Review.

20.

Nonmuscle Myosin II Isoforms Coassemble in Living Cells.

Beach JR, Shao L, Remmert K, Li D, Betzig E, Hammer JA 3rd.

Curr Biol. 2015 Feb 2;25(3):402. doi: 10.1016/j.cub.2015.01.028. Epub 2015 Feb 2. No abstract available.

21.

Lattice light-sheet microscopy: imaging molecules to embryos at high spatiotemporal resolution.

Chen BC, Legant WR, Wang K, Shao L, Milkie DE, Davidson MW, Janetopoulos C, Wu XS, Hammer JA 3rd, Liu Z, English BP, Mimori-Kiyosue Y, Romero DP, Ritter AT, Lippincott-Schwartz J, Fritz-Laylin L, Mullins RD, Mitchell DM, Bembenek JN, Reymann AC, Böhme R, Grill SW, Wang JT, Seydoux G, Tulu US, Kiehart DP, Betzig E.

Science. 2014 Oct 24;346(6208):1257998. doi: 10.1126/science.1257998. Epub 2014 Oct 23.

22.

Nonmuscle myosin II isoforms coassemble in living cells.

Beach JR, Shao L, Remmert K, Li D, Betzig E, Hammer JA 3rd.

Curr Biol. 2014 May 19;24(10):1160-6. doi: 10.1016/j.cub.2014.03.071. Epub 2014 May 8. Erratum in: Curr Biol. 2015 Feb 2;25(3):402. Curr Biol. 2015 Feb 2;25(3):402.

23.

Capping protein regulatory cycle driven by CARMIL and V-1 may promote actin network assembly at protruding edges.

Fujiwara I, Remmert K, Piszczek G, Hammer JA.

Proc Natl Acad Sci U S A. 2014 May 13;111(19):E1970-9. doi: 10.1073/pnas.1313738111. Epub 2014 Apr 28.

24.

Melanosome transfer: it is best to give and receive.

Wu X, Hammer JA.

Curr Opin Cell Biol. 2014 Aug;29:1-7. doi: 10.1016/j.ceb.2014.02.003. Epub 2014 Mar 21. Review.

25.

Organelle interactions: melanosomes and mitochondria get cozy.

Wu X, Hammer JA.

Curr Biol. 2014 Mar 17;24(6):R240-2. doi: 10.1016/j.cub.2014.02.014.

26.

Functions of class V myosins in neurons.

Hammer JA 3rd, Wagner W.

J Biol Chem. 2013 Oct 4;288(40):28428-34. doi: 10.1074/jbc.R113.514497. Epub 2013 Aug 29. Review.

27.

Centrosome repositioning in T cells is biphasic and driven by microtubule end-on capture-shrinkage.

Yi J, Wu X, Chung AH, Chen JK, Kapoor TM, Hammer JA.

J Cell Biol. 2013 Sep 2;202(5):779-92. doi: 10.1083/jcb.201301004. Epub 2013 Aug 26.

28.

Controversy and consensus regarding myosin II function at the immunological synapse.

Hammer JA 3rd, Burkhardt JK.

Curr Opin Immunol. 2013 Jun;25(3):300-6. doi: 10.1016/j.coi.2013.03.010. Epub 2013 Apr 24. Review.

29.

Semi-interpenetrating network (sIPN) gelatin nanofiber scaffolds for oral mucosal drug delivery.

Aduba DC Jr, Hammer JA, Yuan Q, Yeudall WA, Bowlin GL, Yang H.

Acta Biomater. 2013 May;9(5):6576-84. doi: 10.1016/j.actbio.2013.02.006. Epub 2013 Feb 13.

30.

Melanoregulin is stably targeted to the melanosome membrane by palmitoylation.

Wu XS, Martina JA, Hammer JA 3rd.

Biochem Biophys Res Commun. 2012 Sep 21;426(2):209-14. doi: 10.1016/j.bbrc.2012.08.064. Epub 2012 Aug 23.

31.

Rab10 and myosin-Va mediate insulin-stimulated GLUT4 storage vesicle translocation in adipocytes.

Chen Y, Wang Y, Zhang J, Deng Y, Jiang L, Song E, Wu XS, Hammer JA, Xu T, Lippincott-Schwartz J.

J Cell Biol. 2012 Aug 20;198(4):545-60. doi: 10.1083/jcb.201111091.

32.

Melanoregulin regulates a shedding mechanism that drives melanosome transfer from melanocytes to keratinocytes.

Wu XS, Masedunskas A, Weigert R, Copeland NG, Jenkins NA, Hammer JA.

Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):E2101-9. doi: 10.1073/pnas.1209397109. Epub 2012 Jul 2.

33.

The impact of laminin on 3D neurite extension in collagen gels.

Swindle-Reilly KE, Papke JB, Kutosky HP, Throm A, Hammer JA, Harkins AB, Willits RK.

J Neural Eng. 2012 Aug;9(4):046007. doi: 10.1088/1741-2560/9/4/046007. Epub 2012 Jun 27.

PMID:
22736189
34.

Rapid response teams and failure to rescue: one community's experience.

Hammer JA, Jones TL, Brown SA.

J Nurs Care Qual. 2012 Oct-Dec;27(4):352-8. doi: 10.1097/NCQ.0b013e31825a8e2f.

PMID:
22648017
35.

Actin retrograde flow and actomyosin II arc contraction drive receptor cluster dynamics at the immunological synapse in Jurkat T cells.

Yi J, Wu XS, Crites T, Hammer JA 3rd.

Mol Biol Cell. 2012 Mar;23(5):834-52. doi: 10.1091/mbc.E11-08-0731. Epub 2012 Jan 4.

36.

Aspergillus myosin-V supports polarized growth in the absence of microtubule-based transport.

Zhang J, Tan K, Wu X, Chen G, Sun J, Reck-Peterson SL, Hammer JA 3rd, Xiang X.

PLoS One. 2011;6(12):e28575. doi: 10.1371/journal.pone.0028575. Epub 2011 Dec 14.

37.

Walking to work: roles for class V myosins as cargo transporters.

Hammer JA 3rd, Sellers JR.

Nat Rev Mol Cell Biol. 2011 Dec 7;13(1):13-26. doi: 10.1038/nrm3248. Review.

PMID:
22146746
38.

Imaging of lytic granule exocytosis in CD8+ cytotoxic T lymphocytes reveals a modified form of full fusion.

Martina JA, Wu XS, Catalfamo M, Sakamoto T, Yi C, Hammer JA 3rd.

Cell Immunol. 2011;271(2):267-79. doi: 10.1016/j.cellimm.2011.07.004. Epub 2011 Jul 24.

39.

An efficient method for the long-term and specific expression of exogenous cDNAs in cultured Purkinje neurons.

Wagner W, McCroskery S, Hammer JA 3rd.

J Neurosci Methods. 2011 Sep 15;200(2):95-105. doi: 10.1016/j.jneumeth.2011.06.006. Epub 2011 Jun 25.

40.

Two modes of lytic granule fusion during degranulation by natural killer cells.

Liu D, Martina JA, Wu XS, Hammer JA 3rd, Long EO.

Immunol Cell Biol. 2011 Aug;89(6):728-38. doi: 10.1038/icb.2010.167. Epub 2011 Apr 12.

41.

Myosin-Va transports the endoplasmic reticulum into the dendritic spines of Purkinje neurons.

Wagner W, Brenowitz SD, Hammer JA 3rd.

Nat Cell Biol. 2011 Jan;13(1):40-8. doi: 10.1038/ncb2132. Epub 2010 Dec 12.

42.

A new delta-COP on the block--linking pigmentation defects with neurodegeneration.

Wagner W, Hammer JA 3rd.

Pigment Cell Melanoma Res. 2011 Feb;24(1):14-6. doi: 10.1111/j.1755-148X.2010.00818.x. No abstract available.

43.

Molecular basis for barbed end uncapping by CARMIL homology domain 3 of mouse CARMIL-1.

Zwolak A, Uruno T, Piszczek G, Hammer JA 3rd, Tjandra N.

J Biol Chem. 2010 Sep 10;285(37):29014-26. doi: 10.1074/jbc.M110.134221. Epub 2010 Jul 13.

44.

Structural basis for capping protein sequestration by myotrophin (V-1).

Zwolak A, Fujiwara I, Hammer JA 3rd, Tjandra N.

J Biol Chem. 2010 Aug 13;285(33):25767-81. doi: 10.1074/jbc.M110.135848. Epub 2010 Jun 10.

45.

Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearing.

Kitajiri S, Sakamoto T, Belyantseva IA, Goodyear RJ, Stepanyan R, Fujiwara I, Bird JE, Riazuddin S, Riazuddin S, Ahmed ZM, Hinshaw JE, Sellers J, Bartles JR, Hammer JA 3rd, Richardson GP, Griffith AJ, Frolenkov GI, Friedman TB.

Cell. 2010 May 28;141(5):786-98. doi: 10.1016/j.cell.2010.03.049.

46.

Linking molecular motors to membrane cargo.

Akhmanova A, Hammer JA 3rd.

Curr Opin Cell Biol. 2010 Aug;22(4):479-87. doi: 10.1016/j.ceb.2010.04.008. Epub 2010 May 11. Review.

47.

Direct observation of the uncapping of capping protein-capped actin filaments by CARMIL homology domain 3.

Fujiwara I, Remmert K, Hammer JA 3rd.

J Biol Chem. 2010 Jan 22;285(4):2707-20. doi: 10.1074/jbc.M109.031203. Epub 2009 Nov 19.

48.

Dominant-negative myosin Va impairs retrograde but not anterograde axonal transport of large dense core vesicles.

Bittins CM, Eichler TW, Hammer JA 3rd, Gerdes HH.

Cell Mol Neurobiol. 2010 Apr;30(3):369-79. doi: 10.1007/s10571-009-9459-2. Epub 2009 Sep 29.

49.

The Dictyostelium type V myosin MyoJ is responsible for the cortical association and motility of contractile vacuole membranes.

Jung G, Titus MA, Hammer JA 3rd.

J Cell Biol. 2009 Aug 24;186(4):555-70. doi: 10.1083/jcb.200810147. Epub 2009 Aug 17.

50.

Purification of capping protein using the capping protein binding site of CARMIL as an affinity matrix.

Remmert K, Uruno T, Hammer JA 3rd.

Protein Expr Purif. 2009 Oct;67(2):113-9. doi: 10.1016/j.pep.2009.05.002. Epub 2009 May 8.

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