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Motile Dendritic Cells Sense and Respond to Substrate Geometry.

Bendell AC, Anderson N, Blumenthal D, Williamson EK, Chen CS, Burkhardt JK, Hammer DA.

Ann Biomed Eng. 2018 May 22. doi: 10.1007/s10439-018-2041-7. [Epub ahead of print]


Optochemical Control of Protein Localization and Activity within Cell-like Compartments.

Caldwell RM, Bermudez JG, Thai D, Aonbangkhen C, Schuster BS, Courtney T, Deiters A, Hammer DA, Chenoweth DM, Good MC.

Biochemistry. 2018 May 8;57(18):2590-2596. doi: 10.1021/acs.biochem.8b00131. Epub 2018 Apr 19.


Exploring functional pairing between surface glycoconjugates and human galectins using programmable glycodendrimersomes.

Xiao Q, Ludwig AK, Romanò C, Buzzacchera I, Sherman SE, Vetro M, Vértesy S, Kaltner H, Reed EH, Möller M, Wilson CJ, Hammer DA, Oscarson S, Klein ML, Gabius HJ, Percec V.

Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):E2509-E2518. doi: 10.1073/pnas.1720055115. Epub 2018 Jan 30.


Technique for insulated and non-insulated metal liner X-pinch radiography on a 1 MA pulsed power machine.

Atoyan L, Shelkovenko TA, Pikuz SA, Hammer DA, Byvank T, Greenly JB, Potter WM.

Rev Sci Instrum. 2017 Nov;88(11):113502. doi: 10.1063/1.4989985.


Migration against the direction of flow is LFA-1-dependent in human hematopoietic stem and progenitor cells.

Buffone A Jr, Anderson NR, Hammer DA.

J Cell Sci. 2018 Jan 10;131(1). pii: jcs205575. doi: 10.1242/jcs.205575.


Janus dendrimersomes coassembled from fluorinated, hydrogenated, and hybrid Janus dendrimers as models for cell fusion and fission.

Xiao Q, Sherman SE, Wilner SE, Zhou X, Dazen C, Baumgart T, Reed EH, Hammer DA, Shinoda W, Klein ML, Percec V.

Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):E7045-E7053. doi: 10.1073/pnas.1708380114. Epub 2017 Aug 7.


The Arp2/3 complex binding protein HS1 is required for efficient dendritic cell random migration and force generation.

Bendell AC, Williamson EK, Chen CS, Burkhardt JK, Hammer DA.

Integr Biol (Camb). 2017 Aug 14;9(8):695-708. doi: 10.1039/c7ib00070g.


A compact linear accelerator based on a scalable microelectromechanical-system RF-structure.

Persaud A, Ji Q, Feinberg E, Seidl PA, Waldron WL, Schenkel T, Lal A, Vinayakumar KB, Ardanuc S, Hammer DA.

Rev Sci Instrum. 2017 Jun;88(6):063304. doi: 10.1063/1.4984969.


Effect of M1-M2 Polarization on the Motility and Traction Stresses of Primary Human Macrophages.

Hind LE, Lurier EB, Dembo M, Spiller KL, Hammer DA.

Cell Mol Bioeng. 2016 Sep;9(3):455-465. doi: 10.1007/s12195-016-0435-x. Epub 2016 Apr 18.


A Case Report of the First Nonburn-related Military Trauma Victim Treated with Spray Skin Regenerative Therapy in Combination with a Dermal Regenerate Template.

Valerio IL, Hammer DA, Rendon JL, Latham KP, Fleming ME.

Plast Reconstr Surg Glob Open. 2016 Dec 27;4(12):e1174. doi: 10.1097/GOX.0000000000001174. eCollection 2016 Dec.


Why Do Membranes of Some Unhealthy Cells Adopt a Cubic Architecture?

Xiao Q, Wang Z, Williams D, Leowanawat P, Peterca M, Sherman SE, Zhang S, Hammer DA, Heiney PA, King SR, Markovitz DM, André S, Gabius HJ, Klein ML, Percec V.

ACS Cent Sci. 2016 Dec 28;2(12):943-953. doi: 10.1021/acscentsci.6b00284. Epub 2016 Dec 5.


Injectable, Guest-Host Assembled Polyethylenimine Hydrogel for siRNA Delivery.

Wang LL, Sloand JN, Gaffey AC, Venkataraman CM, Wang Z, Trubelja A, Hammer DA, Atluri P, Burdick JA.

Biomacromolecules. 2017 Jan 9;18(1):77-86. doi: 10.1021/acs.biomac.6b01378. Epub 2016 Dec 20.


Measuring 20-100 T B-fields using Zeeman splitting of sodium emission lines on a 500 kA pulsed power machine.

Banasek JT, Engelbrecht JT, Pikuz SA, Shelkovenko TA, Hammer DA.

Rev Sci Instrum. 2016 Nov;87(11):11D407.


Measuring 10-20 T magnetic fields in single wire explosions using Zeeman splitting.

Banasek JT, Engelbrecht JT, Pikuz SA, Shelkovenko TA, Hammer DA.

Rev Sci Instrum. 2016 Oct;87(10):103506.


Self-Sorting and Coassembly of Fluorinated, Hydrogenated, and Hybrid Janus Dendrimers into Dendrimersomes.

Xiao Q, Rubien JD, Wang Z, Reed EH, Hammer DA, Sahoo D, Heiney PA, Yadavalli SS, Goulian M, Wilner SE, Baumgart T, Vinogradov SA, Klein ML, Percec V.

J Am Chem Soc. 2016 Sep 28;138(38):12655-63. doi: 10.1021/jacs.6b08069. Epub 2016 Sep 14.


Protease-Triggered, Integrin-Targeted Cellular Uptake of Recombinant Protein Micelles.

Gao C, Vargo KB, Hammer DA.

Macromol Biosci. 2016 Sep;16(9):1398-406. doi: 10.1002/mabi.201600032. Epub 2016 Jun 10.


Bioactive cell-like hybrids coassembled from (glyco)dendrimersomes with bacterial membranes.

Xiao Q, Yadavalli SS, Zhang S, Sherman SE, Fiorin E, da Silva L, Wilson DA, Hammer DA, André S, Gabius HJ, Klein ML, Goulian M, Percec V.

Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1134-41. doi: 10.1073/pnas.1525589113. Epub 2016 Feb 16.


Onion-like glycodendrimersomes from sequence-defined Janus glycodendrimers and influence of architecture on reactivity to a lectin.

Xiao Q, Zhang S, Wang Z, Sherman SE, Moussodia RO, Peterca M, Muncan A, Williams DR, Hammer DA, Vértesy S, André S, Gabius HJ, Klein ML, Percec V.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1162-7. doi: 10.1073/pnas.1524976113. Epub 2016 Jan 19.


Eosinophilic Esophagitis-Associated Chemical and Mechanical Microenvironment Shapes Esophageal Fibroblast Behavior.

Muir AB, Dods K, Henry SJ, Benitez AJ, Lee D, Whelan KA, DeMarshall M, Hammer DA, Falk G, Wells RG, Spergel J, Nakagawa H, Wang ML.

J Pediatr Gastroenterol Nutr. 2016 Aug;63(2):200-9. doi: 10.1097/MPG.0000000000001100.


Stiff substrates enhance monocytic cell capture through E-selectin but not P-selectin.

MacKay JL, Hammer DA.

Integr Biol (Camb). 2016 Jan;8(1):62-72. doi: 10.1039/c5ib00199d. Epub 2015 Dec 2.


Enzymatically triggered rupture of polymersomes.

Jang WS, Park SC, Reed EH, Dooley KP, Wheeler SF, Lee D, Hammer DA.

Soft Matter. 2016 Jan 28;12(4):1014-20. doi: 10.1039/c5sm01881a.


Quantifying patient bacterial exposure risk from reusable phlebotomy tourniquets in a New Zealand secondary level hospital.

Schauer CK, Hammer DA.

J Infect Prev. 2015 Nov;16(6):262-265. doi: 10.1177/1757177415600242. Epub 2015 Aug 21.


Glycodendrimersomes from Sequence-Defined Janus Glycodendrimers Reveal High Activity and Sensor Capacity for the Agglutination by Natural Variants of Human Lectins.

Zhang S, Xiao Q, Sherman SE, Muncan A, Ramos Vicente AD, Wang Z, Hammer DA, Williams D, Chen Y, Pochan DJ, Vértesy S, André S, Klein ML, Gabius HJ, Percec V.

J Am Chem Soc. 2015 Oct 21;137(41):13334-44. doi: 10.1021/jacs.5b08844. Epub 2015 Oct 7.


Protrusive and Contractile Forces of Spreading Human Neutrophils.

Henry SJ, Chen CS, Crocker JC, Hammer DA.

Biophys J. 2015 Aug 18;109(4):699-709. doi: 10.1016/j.bpj.2015.05.041.


Motile Human Neutrophils Sense Ligand Density Over Their Entire Contact Area.

Henry SJ, Crocker JC, Hammer DA.

Ann Biomed Eng. 2016 Apr;44(4):886-94. doi: 10.1007/s10439-015-1408-2. Epub 2015 Jul 29.


Macrophage motility is driven by frontal-towing with a force magnitude dependent on substrate stiffness.

Hind LE, Dembo M, Hammer DA.

Integr Biol (Camb). 2015 Apr;7(4):447-53. doi: 10.1039/c4ib00260a.


The direction of migration of T-lymphocytes under flow depends upon which adhesion receptors are engaged.

Dominguez GA, Anderson NR, Hammer DA.

Integr Biol (Camb). 2015 Mar;7(3):345-55. doi: 10.1039/c4ib00201f. Epub 2015 Feb 12.


Immobilized IL-8 Triggers Phagocytosis and Dynamic Changes in Membrane Microtopology in Human Neutrophils.

Beste MT, Lomakina EB, Hammer DA, Waugh RE.

Ann Biomed Eng. 2015 Sep;43(9):2207-19. doi: 10.1007/s10439-014-1242-y. Epub 2015 Jan 13.


Caging metal ions with visible light-responsive nanopolymersomes.

Griepenburg JC, Sood N, Vargo KB, Williams D, Rawson J, Therien MJ, Hammer DA, Dmochowski IJ.

Langmuir. 2015 Jan 20;31(2):799-807. doi: 10.1021/la5036689. Epub 2015 Jan 7.


The effect of stabilizer on the mechanical response of double-emulsion-templated polymersomes.

Jang WS, Park SC, Kim M, Doh J, Lee D, Hammer DA.

Macromol Rapid Commun. 2015 Feb;36(4):378-84. doi: 10.1002/marc.201400472. Epub 2014 Dec 16.


Superparamagnetic iron oxide nanoparticle micelles stabilized by recombinant oleosin for targeted magnetic resonance imaging.

Vargo KB, Zaki AA, Warden-Rothman R, Tsourkas A, Hammer DA.

Small. 2015 Mar 25;11(12):1409-13. doi: 10.1002/smll.201402017. Epub 2014 Nov 22.


A doubly curved elliptical crystal spectrometer for the study of localized x-ray absorption in hot plasmas.

Cahill AD, Hoyt CL, Pikuz SA, Shelkovenko T, Hammer DA.

Rev Sci Instrum. 2014 Oct;85(10):103114. doi: 10.1063/1.4898339.


Noncanonical self-assembly of highly asymmetric genetically encoded polypeptide amphiphiles into cylindrical micelles.

McDaniel JR, Weitzhandler I, Prevost S, Vargo KB, Appavou MS, Hammer DA, Gradzielski M, Chilkoti A.

Nano Lett. 2014 Nov 12;14(11):6590-8. doi: 10.1021/nl503221p. Epub 2014 Oct 2.


Recombinant protein-stabilized monodisperse microbubbles with tunable size using a valve-based microfluidic device.

Angilè FE, Vargo KB, Sehgal CM, Hammer DA, Lee D.

Langmuir. 2014 Oct 28;30(42):12610-8. doi: 10.1021/la502610c. Epub 2014 Oct 13.


Two-dimensional motility of a macrophage cell line on microcontact-printed fibronectin.

Hind LE, Mackay JL, Cox D, Hammer DA.

Cytoskeleton (Hoboken). 2014 Sep;71(9):542-54. doi: 10.1002/cm.21191. Epub 2014 Oct 3.


Spherical micelles assembled from variants of recombinant oleosin.

Vargo KB, Sood N, Moeller TD, Heiney PA, Hammer DA.

Langmuir. 2014 Sep 30;30(38):11292-300. doi: 10.1021/la502664e. Epub 2014 Sep 22.


The cancer glycocalyx mechanically primes integrin-mediated growth and survival.

Paszek MJ, DuFort CC, Rossier O, Bainer R, Mouw JK, Godula K, Hudak JE, Lakins JN, Wijekoon AC, Cassereau L, Rubashkin MG, Magbanua MJ, Thorn KS, Davidson MW, Rugo HS, Park JW, Hammer DA, Giannone G, Bertozzi CR, Weaver VM.

Nature. 2014 Jul 17;511(7509):319-25. doi: 10.1038/nature13535. Epub 2014 Jun 25.


Effect of adhesion and chemokine presentation on T-lymphocyte haptokinesis.

Dominguez GA, Hammer DA.

Integr Biol (Camb). 2014 Sep;6(9):862-73. doi: 10.1039/c4ib00094c.


Ligand density elicits a phenotypic switch in human neutrophils.

Henry SJ, Crocker JC, Hammer DA.

Integr Biol (Camb). 2014 Mar;6(3):348-56. doi: 10.1039/c3ib40225h. Epub 2014 Jan 31.


Adhesive dynamics.

Hammer DA.

J Biomech Eng. 2014 Feb;136(2):021006. doi: 10.1115/1.4026402. Review.


Single-vesicle patterning of uniform, giant polymersomes into microarrays.

Kamat NP, Henry SJ, Lee D, Hammer DA.

Small. 2013 Jul 8;9(13):2272-6. doi: 10.1002/smll.201202627. Epub 2013 Mar 6.


Isolation of αL I domain mutants mediating firm cell adhesion using a novel flow-based sorting method.

Pepper LR, Parthasarathy R, Robbins GP, Dang NN, Hammer DA, Boder ET.

Protein Eng Des Sel. 2013 Aug;26(8):515-21. doi: 10.1093/protein/gzt028. Epub 2013 Jun 19.


Modular synthesis of amphiphilic Janus glycodendrimers and their self-assembly into glycodendrimersomes and other complex architectures with bioactivity to biomedically relevant lectins.

Percec V, Leowanawat P, Sun HJ, Kulikov O, Nusbaum CD, Tran TM, Bertin A, Wilson DA, Peterca M, Zhang S, Kamat NP, Vargo K, Moock D, Johnston ED, Hammer DA, Pochan DJ, Chen Y, Chabre YM, Shiao TC, Bergeron-Brlek M, André S, Roy R, Gabius HJ, Heiney PA.

J Am Chem Soc. 2013 Jun 19;135(24):9055-77. doi: 10.1021/ja403323y. Epub 2013 Jun 6.


Self-assembly of thermally responsive nanoparticles of a genetically encoded peptide polymer by drug conjugation.

McDaniel JR, Bhattacharyya J, Vargo KB, Hassouneh W, Hammer DA, Chilkoti A.

Angew Chem Int Ed Engl. 2013 Feb 4;52(6):1683-7. doi: 10.1002/anie.201200899. Epub 2012 Dec 20. No abstract available.


Biodegradable Polymersomes for the Delivery of Gemcitabine to Panc-1 Cells.

Sood N, Jenkins WT, Yang XY, Shah NN, Katz JS, Koch CJ, Frail PR, Therien MJ, Hammer DA, Evans SM.

J Pharm (Cairo). 2013;2013. pii: 932797.


Fiber alignment directs cell motility over chemotactic gradients.

Sundararaghavan HG, Saunders RL, Hammer DA, Burdick JA.

Biotechnol Bioeng. 2013 Apr;110(4):1249-54. doi: 10.1002/bit.24788. Epub 2012 Dec 28.


A collinear self-emission and laser-backlighting imaging diagnostic.

Bott SC, Collins G 4th, Gunasekera K, Mariscal D, Beg FN, Haas DM, Veloso F, Blesener IC, Cahill AD, Hoyt CL, Kusse BR, Hammer DA.

Rev Sci Instrum. 2012 Aug;83(8):083507. doi: 10.1063/1.4746996.


Calibration and analysis of spatially resolved x-ray absorption spectra from a nonuniform plasma.

Knapp PF, Hansen SB, Pikuz SA, Shelkovenko TA, Hammer DA.

Rev Sci Instrum. 2012 Jul;83(7):073502. doi: 10.1063/1.4731664.


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