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Clinical implications of increased testing in primary care.

Watson J, Hamilton F, Bailey S, Mounce L, Hamilton W.

BMJ. 2019 Jan 15;364:l175. doi: 10.1136/bmj.l175. No abstract available.


Association of Primary Care Consultation Patterns With Early Signs and Symptoms of Psychosis.

Sullivan SA, Hamilton W, Tilling K, Redaniel T, Moran P, Lewis G.

JAMA Netw Open. 2018 Nov 2;1(7):e185174. doi: 10.1001/jamanetworkopen.2018.5174.


Development of an intervention to expedite cancer diagnosis through primary care: a protocol.

Stanciu MA, Law RJ, Nafees S, Hendry M, Yeo ST, Hiscock J, Lewis R, Edwards RT, Williams NH, Brain K, Brocklehurst P, Carson-Stevens A, Dolwani S, Emery J, Hamilton W, Hoare Z, Lyratzopoulos G, Rubin G, Smits S, Vedsted P, Walter F, Wilkinson C, Neal RD; WICKED Team on behalf of.

BJGP Open. 2018 Sep 5;2(3):bjgpopen18X101595. doi: 10.3399/bjgpopen18X101595. eCollection 2018 Oct.


Whole-colon investigation vs. flexible sigmoidoscopy for suspected colorectal cancer based on presenting symptoms and signs: a multicentre cohort study.

Cross AJ, Wooldrage K, Robbins EC, Pack K, Brown JP, Hamilton W, Thompson MR, Flashman KG, Halligan S, Thomas-Gibson S, Vance M, Saunders BP, Atkin W.

Br J Cancer. 2018 Dec 19. doi: 10.1038/s41416-018-0335-z. [Epub ahead of print]


Associations between general practice characteristics with use of urgent referrals for suspected cancer and endoscopies: a cross-sectional ecological study.

Mendonca SC, Abel GA, Gildea C, McPhail S, Peake MD, Rubin G, Singh H, Hamilton W, Walter FM, Roland MO, Lyratzopoulos G.

Fam Pract. 2018 Dec 12. doi: 10.1093/fampra/cmy118. [Epub ahead of print]


Can Elite Dancers Return to Dance After Ultrasound-Guided Platelet-Rich Plasma (PRP) Injections?

Jain N, Bauman PA, Hamilton WG, Merkle A, Adler RS.

J Dance Med Sci. 2018 Dec 1;22(4):225-232. doi: 10.12678/1089-313X.22.4.225.


The impact of health literacy on diagnosis and outcomes of symptomatic cancer by ethnicity: a systematic review protocol.

Chiva Giurca B, Hamilton W, Martins T.

Syst Rev. 2018 Oct 17;7(1):164. doi: 10.1186/s13643-018-0831-5.


The Aarhus statement on cancer diagnostic research: turning recommendations into new survey instruments.

Coxon D, Campbell C, Walter FM, Scott SE, Neal RD, Vedsted P, Emery J, Rubin G, Hamilton W, Weller D.

BMC Health Serv Res. 2018 Sep 3;18(1):677. doi: 10.1186/s12913-018-3476-0.


Open Re-rupture of the Achilles Tendon Following Minimally Invasive Repair: A Case Report.

de Cesar Netto C, Bernasconi A, Roberts L, Saito GH, Hamilton WG, O'Malley MJ.

J Foot Ankle Surg. 2018 Nov - Dec;57(6):1272-1277. doi: 10.1053/j.jfas.2018.04.002. Epub 2018 Aug 13.


Early detection of multiple myeloma in primary care using blood tests: a case-control study in primary care.

Koshiaris C, Van den Bruel A, Oke JL, Nicholson BD, Shephard E, Braddick M, Hamilton W.

Br J Gen Pract. 2018 Sep;68(674):e586-e593. doi: 10.3399/bjgp18X698357. Epub 2018 Aug 13.


Prostate Cancer in Primary Care.

Merriel SWD, Funston G, Hamilton W.

Adv Ther. 2018 Sep;35(9):1285-1294. doi: 10.1007/s12325-018-0766-1. Epub 2018 Aug 10. Review.


Case-finding in clinical practice: An appropriate strategy for dementia identification?

Ranson JM, Kuźma E, Hamilton W, Lang I, Llewellyn DJ.

Alzheimers Dement (N Y). 2018 Jul 10;4:288-296. doi: 10.1016/j.trci.2018.04.011. eCollection 2018. Review.


Patient understanding and acceptability of an early lung cancer diagnosis trial: a qualitative study.

Prout HC, Barham A, Bongard E, Tudor-Edwards R, Griffiths G, Hamilton W, Harrop E, Hood K, Hurt CN, Nelson R, Porter C, Roberts K, Rogers T, Thomas-Jones E, Tod A, Yeo ST, Neal RD, Nelson A.

Trials. 2018 Aug 4;19(1):419. doi: 10.1186/s13063-018-2803-4.


Sex and BMI Alter the Benefits and Risks of Sulfonylureas and Thiazolidinediones in Type 2 Diabetes: A Framework for Evaluating Stratification Using Routine Clinical and Individual Trial Data.

Dennis JM, Henley WE, Weedon MN, Lonergan M, Rodgers LR, Jones AG, Hamilton WT, Sattar N, Janmohamed S, Holman RR, Pearson ER, Shields BM, Hattersley AT; MASTERMIND Consortium.

Diabetes Care. 2018 Sep;41(9):1844-1853. doi: 10.2337/dc18-0344. Epub 2018 Aug 2.


Selection of men for investigation of possible testicular cancer in primary care: a large case-control study using electronic patient records.

Shephard EA, Hamilton WT.

Br J Gen Pract. 2018 Aug;68(673):e559-e565. doi: 10.3399/bjgp18X697949. Epub 2018 Jul 2. Erratum in: Br J Gen Pract. 2018 Sep;68(674):416.


Using CPRD data for public health research.

Hamilton W.

Br J Gen Pract. 2018 Jul;68(672):334. doi: 10.3399/bjgp18X697745. No abstract available.


Long read assemblies of geographically dispersed Plasmodium falciparum isolates reveal highly structured subtelomeres.

Otto TD, Böhme U, Sanders M, Reid A, Bruske EI, Duffy CW, Bull PC, Pearson RD, Abdi A, Dimonte S, Stewart LB, Campino S, Kekre M, Hamilton WL, Claessens A, Volkman SK, Ndiaye D, Amambua-Ngwa A, Diakite M, Fairhurst RM, Conway DJ, Franck M, Newbold CI, Berriman M.

Wellcome Open Res. 2018 May 3;3:52. doi: 10.12688/wellcomeopenres.14571.1. eCollection 2018.


Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome.

Weinert BT, Narita T, Satpathy S, Srinivasan B, Hansen BK, Schölz C, Hamilton WB, Zucconi BE, Wang WW, Liu WR, Brickman JM, Kesicki EA, Lai A, Bromberg KD, Cole PA, Choudhary C.

Cell. 2018 Jun 28;174(1):231-244.e12. doi: 10.1016/j.cell.2018.04.033. Epub 2018 May 24.


Health economic evaluation of a serum-based blood test for brain tumour diagnosis: exploration of two clinical scenarios.

Gray E, Butler HJ, Board R, Brennan PM, Chalmers AJ, Dawson T, Goodden J, Hamilton W, Hegarty MG, James A, Jenkinson MD, Kernick D, Lekka E, Livermore LJ, Mills SJ, O'Neill K, Palmer DS, Vaqas B, Baker MJ.

BMJ Open. 2018 May 24;8(5):e017593. doi: 10.1136/bmjopen-2017-017593.


Proton-Pump Inhibitors and Long-Term Risk of Community-Acquired Pneumonia in Older Adults.

Zirk-Sadowski J, Masoli JA, Delgado J, Hamilton W, Strain WD, Henley W, Melzer D, Ble A.

J Am Geriatr Soc. 2018 Jul;66(7):1332-1338. doi: 10.1111/jgs.15385. Epub 2018 Apr 20.


Cancer incidence in patients with a high normal platelet count: a cohort study using primary care data.

Ankus E, Price SJ, Ukoumunne OC, Hamilton W, Bailey SER.

Fam Pract. 2018 Dec 12;35(6):671-675. doi: 10.1093/fampra/cmy018.


Weight loss as a predictor of cancer in primary care: a systematic review and meta-analysis.

Nicholson BD, Hamilton W, O'Sullivan J, Aveyard P, Hobbs FR.

Br J Gen Pract. 2018 May;68(670):e311-e322. doi: 10.3399/bjgp18X695801. Epub 2018 Apr 9.


Correction to: Recognizing Gynecological Cancer in Primary Care: Risk Factors, Red Flags, and Referrals.

Funston G, O'Flynn H, Ryan NAJ, Hamilton W, Crosbie EJ.

Adv Ther. 2018 Apr;35(4):590. doi: 10.1007/s12325-018-0692-2.


Evaluation of an intervention promoting emotion regulation skills for adults with persisting distress due to adverse childhood experiences.

Cameron LD, Carroll P, Hamilton WK.

Child Abuse Negl. 2018 May;79:423-433. doi: 10.1016/j.chiabu.2018.03.002. Epub 2018 Mar 20.


Global Incidence and mortality of oesophageal cancer and their correlation with socioeconomic indicators temporal patterns and trends in 41 countries.

Wong MCS, Hamilton W, Whiteman DC, Jiang JY, Qiao Y, Fung FDH, Wang HHX, Chiu PWY, Ng EKW, Wu JCY, Yu J, Chan FKL, Sung JJY.

Sci Rep. 2018 Mar 14;8(1):4522. doi: 10.1038/s41598-018-19819-8.


Recognizing Gynecological Cancer in Primary Care: Risk Factors, Red Flags, and Referrals.

Funston G, O'Flynn H, Ryan NAJ, Hamilton W, Crosbie EJ.

Adv Ther. 2018 Apr;35(4):577-589. doi: 10.1007/s12325-018-0683-3. Epub 2018 Mar 7. Erratum in: Adv Ther. 2018 Apr 4;:.


Operating room traffic in total joint arthroplasty: Identifying patterns and training the team to keep the door shut.

Hamilton WG, Balkam CB, Purcell RL, Parks NL, Holdsworth JE.

Am J Infect Control. 2018 Jun;46(6):633-636. doi: 10.1016/j.ajic.2017.12.019. Epub 2018 Feb 15.


The Lawrence D. Dorr Surgical Techniques & Technologies Award: "Running Two Rooms" Does Not Compromise Outcomes or Patient Safety in Joint Arthroplasty.

Hamilton WG, Ho H, Parks NL, Strait AV, Hopper RH Jr, McDonald JF 3rd, Goyal N, Fricka KB, Engh CA Jr.

J Arthroplasty. 2018 Jul;33(7S):S8-S12. doi: 10.1016/j.arth.2018.01.011. Epub 2018 Jan 31.


Symptoms in primary care with time to diagnosis of brain tumours.

Ozawa M, Brennan PM, Zienius K, Kurian KM, Hollingworth W, Weller D, Hamilton W, Grant R, Ben-Shlomo Y.

Fam Pract. 2018 Sep 18;35(5):551-558. doi: 10.1093/fampra/cmx139.


Imported gnathostomiasis manifesting as cutaneous larva migrans and Löffler's syndrome.

Hamilton WL, Agranoff D.

BMJ Case Rep. 2018 Feb 2;2018. pii: bcr-2017-223132. doi: 10.1136/bcr-2017-223132.


The nature and frequency of abdominal symptoms in cancer patients and their associations with time to help-seeking: evidence from a national audit of cancer diagnosis.

Koo MM, von Wagner C, Abel GA, McPhail S, Hamilton W, Rubin GP, Lyratzopoulos G.

J Public Health (Oxf). 2018 Sep 1;40(3):e388-e395. doi: 10.1093/pubmed/fdx188.


Elevated vasopressin in pregnant mice induces T-helper subset alterations consistent with human preeclampsia.

Scroggins SM, Santillan DA, Lund JM, Sandgren JA, Krotz LK, Hamilton WS, Devor EJ, Davis HA, Pierce GL, Gibson-Corley KN, Sigmund CD, Grobe JL, Santillan MK.

Clin Sci (Lond). 2018 Feb 14;132(3):419-436. doi: 10.1042/CS20171059. Print 2018 Feb 14.


Loyalty in Online Communities.

Hamilton WL, Zhang J, Danescu-Niculescu-Mizil C, Jurafsky D, Leskovec J.

Proc Int AAAI Conf Weblogs Soc Media. 2017 May;2017:540-543.


Community Identity and User Engagement in a Multi-Community Landscape.

Zhang J, Hamilton WL, Danescu-Niculescu-Mizil C, Jurafsky D, Leskovec J.

Proc Int AAAI Conf Weblogs Soc Media. 2017 May;2017:377-386.


Harnessing the power of intelligent machines to enhance primary care.

Moore SF, Hamilton W, Llewellyn DJ.

Br J Gen Pract. 2018 Jan;68(666):6-7. doi: 10.3399/bjgp17X693965. No abstract available.


Associations between diagnostic activity and measures of patient experience in primary care: a cross-sectional ecological study of English general practices.

Lyratzopoulos G, Mendonca SC, Gildea C, McPhail S, Peake MD, Rubin G, Singh H, Hamilton W, Walter FM, Roland M, Abel GA.

Br J Gen Pract. 2018 Jan;68(666):e9-e17. doi: 10.3399/bjgp17X694097. Epub 2017 Dec 18.


Symptom Signatures and Diagnostic Timeliness in Cancer Patients: A Review of Current Evidence.

Koo MM, Hamilton W, Walter FM, Rubin GP, Lyratzopoulos G.

Neoplasia. 2018 Feb;20(2):165-174. doi: 10.1016/j.neo.2017.11.005. Epub 2017 Dec 16. Review.


The researchers' role in knowledge translation: a realist evaluation of the development and implementation of diagnostic pathways for cancer in two United Kingdom localities.

Banks J, Wye L, Hall N, Rooney J, Walter FM, Hamilton W, Gjini A, Rubin G.

Health Res Policy Syst. 2017 Dec 13;15(1):103. doi: 10.1186/s12961-017-0267-8.


Lumbar chance fracture after direct anterior total hip arthroplasty.

Pitta M, Wallach CJ, Bauk C, Hamilton WG.

Arthroplast Today. 2017 Jul 10;3(4):247-250. doi: 10.1016/j.artd.2017.05.010. eCollection 2017 Dec.


Variation in 'fast-track' referrals for suspected cancer by patient characteristic and cancer diagnosis: evidence from 670 000 patients with cancers of 35 different sites.

Zhou Y, Mendonca SC, Abel GA, Hamilton W, Walter FM, Johnson S, Shelton J, Elliss-Brookes L, McPhail S, Lyratzopoulos G.

Br J Cancer. 2018 Jan;118(1):24-31. doi: 10.1038/bjc.2017.381. Epub 2017 Nov 28.


Identifying clinical features in primary care electronic health record studies: methods for codelist development.

Watson J, Nicholson BD, Hamilton W, Price S.

BMJ Open. 2017 Nov 22;7(11):e019637. doi: 10.1136/bmjopen-2017-019637.


Is whole-colon investigation by colonoscopy, computerised tomography colonography or barium enema necessary for all patients with colorectal cancer symptoms, and for which patients would flexible sigmoidoscopy suffice? A retrospective cohort study.

Atkin W, Wooldrage K, Shah U, Skinner K, Brown JP, Hamilton W, Kralj-Hans I, Thompson MR, Flashman KG, Halligan S, Thomas-Gibson S, Vance M, Cross AJ.

Health Technol Assess. 2017 Nov;21(66):1-80. doi: 10.3310/hta21660.


Identifying frailty in primary care.

Hamilton W, Round J.

BMJ. 2017 Sep 27;358:j4478. doi: 10.1136/bmj.j4478. No abstract available.


Insulin fine-tunes self-renewal pathways governing naive pluripotency and extra-embryonic endoderm.

Anderson KGV, Hamilton WB, Roske FV, Azad A, Knudsen TE, Canham MA, Forrester LM, Brickman JM.

Nat Cell Biol. 2017 Oct;19(10):1164-1177. doi: 10.1038/ncb3617. Epub 2017 Sep 25.


The effect of crowder charge in a model polymer-colloid system for macromolecular crowding: Polymer structure and dynamics.

Palit S, He L, Hamilton WA, Yethiraj A, Yethiraj A.

J Chem Phys. 2017 Sep 21;147(11):114902. doi: 10.1063/1.4986353.


Are we missing hypoglycaemia? Elderly patients with insulin-treated diabetes present to primary care frequently with non-specific symptoms associated with hypoglycaemia.

Hope SV, Taylor PJ, Shields BM, Hattersley AT, Hamilton W.

Prim Care Diabetes. 2018 Apr;12(2):139-146. doi: 10.1016/j.pcd.2017.08.004. Epub 2017 Sep 11.


Understanding symptom appraisal and help-seeking in people with symptoms suggestive of pancreatic cancer: a qualitative study.

Mills K, Birt L, Emery JD, Hall N, Banks J, Johnson M, Lancaster J, Hamilton W, Rubin GP, Walter FM.

BMJ Open. 2017 Sep 3;7(9):e015682. doi: 10.1136/bmjopen-2016-015682.


Perioperative Pain Management and Anesthesia: A Critical Component to Rapid Recovery Total Joint Arthroplasty.

Russo MW, Parks NL, Hamilton WG.

Orthop Clin North Am. 2017 Oct;48(4):401-405. doi: 10.1016/j.ocl.2017.06.006. Review.


Comparison of Wound Complications and Deep Infections With Direct Anterior and Posterior Approaches in Obese Hip Arthroplasty Patients.

Purcell RL, Parks NL, Cody JP, Hamilton WG.

J Arthroplasty. 2018 Jan;33(1):220-223. doi: 10.1016/j.arth.2017.07.047. Epub 2017 Aug 4.


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