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Items: 36

1.

Resurrection of ancestral effector caspases identifies novel networks for evolution of substrate specificity.

Grinshpon RD, Shrestha S, Titus-McQuillan J, Hamilton PT, Swartz PD, Clark AC.

Biochem J. 2019 Nov 29;476(22):3475-3492. doi: 10.1042/BCJ20190625.

2.

Cancer stemness, intratumoral heterogeneity, and immune response across cancers.

Miranda A, Hamilton PT, Zhang AW, Pattnaik S, Becht E, Mezheyeuski A, Bruun J, Micke P, de Reynies A, Nelson BH.

Proc Natl Acad Sci U S A. 2019 Apr 30;116(18):9020-9029. doi: 10.1073/pnas.1818210116. Epub 2019 Apr 17.

3.

Genetics and Genomics of an Unusual Selfish Sex Ratio Distortion in an Insect.

Hamilton PT, Hodson CN, Curtis CI, Perlman SJ.

Curr Biol. 2018 Dec 3;28(23):3864-3870.e4. doi: 10.1016/j.cub.2018.10.035. Epub 2018 Nov 15.

4.

Interfaces of Malignant and Immunologic Clonal Dynamics in Ovarian Cancer.

Zhang AW, McPherson A, Milne K, Kroeger DR, Hamilton PT, Miranda A, Funnell T, Little N, de Souza CPE, Laan S, LeDoux S, Cochrane DR, Lim JLP, Yang W, Roth A, Smith MA, Ho J, Tse K, Zeng T, Shlafman I, Mayo MR, Moore R, Failmezger H, Heindl A, Wang YK, Bashashati A, Grewal DS, Brown SD, Lai D, Wan ANC, Nielsen CB, Huebner C, Tessier-Cloutier B, Anglesio MS, Bouchard-Côté A, Yuan Y, Wasserman WW, Gilks CB, Karnezis AN, Aparicio S, McAlpine JN, Huntsman DG, Holt RA, Nelson BH, Shah SP.

Cell. 2018 Jun 14;173(7):1755-1769.e22. doi: 10.1016/j.cell.2018.03.073. Epub 2018 May 10.

5.

Mutational Analysis of Gene Fusions Predicts Novel MHC Class I-Restricted T-Cell Epitopes and Immune Signatures in a Subset of Prostate Cancer.

Kalina JL, Neilson DS, Lin YY, Hamilton PT, Comber AP, Loy EMH, Sahinalp SC, Collins CC, Hach F, Lum JJ.

Clin Cancer Res. 2017 Dec 15;23(24):7596-7607. doi: 10.1158/1078-0432.CCR-17-0618. Epub 2017 Sep 27.

6.

An Internship May Not Be Enough: Enhancing Bioscience Industry Job Readiness through Practicum Experiences.

Cramer JM, Hamilton PT.

J Microbiol Biol Educ. 2017 Apr 21;18(1). pii: 18.1.20. doi: 10.1128/jmbe.v18i1.1248. eCollection 2017 Apr.

7.

Paternal Genome Elimination in Liposcelis Booklice (Insecta: Psocodea).

Hodson CN, Hamilton PT, Dilworth D, Nelson CJ, Curtis CI, Perlman SJ.

Genetics. 2017 Jun;206(2):1091-1100. doi: 10.1534/genetics.117.199786. Epub 2017 Mar 14.

8.

Immune genes and divergent antimicrobial peptides in flies of the subgenus Drosophila.

Hanson MA, Hamilton PT, Perlman SJ.

BMC Evol Biol. 2016 Oct 24;16(1):228.

9.

Phage display and structural studies reveal plasticity in substrate specificity of caspase-3a from zebrafish.

Tucker MB, MacKenzie SH, Maciag JJ, Dirscherl Ackerman H, Swartz P, Yoder JA, Hamilton PT, Clay Clark A.

Protein Sci. 2016 Nov;25(11):2076-2088. doi: 10.1002/pro.3032. Epub 2016 Sep 14.

10.

Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA-RON2 pair.

Parker ML, Penarete-Vargas DM, Hamilton PT, Guérin A, Dubey JP, Perlman SJ, Spano F, Lebrun M, Boulanger MJ.

Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):398-403. doi: 10.1073/pnas.1515898113. Epub 2015 Dec 28.

11.

A ribosome-inactivating protein in a Drosophila defensive symbiont.

Hamilton PT, Peng F, Boulanger MJ, Perlman SJ.

Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):350-5. doi: 10.1073/pnas.1518648113. Epub 2015 Dec 28.

12.

Infection Dynamics and Immune Response in a Newly Described Drosophila-Trypanosomatid Association.

Hamilton PT, Votýpka J, Dostálová A, Yurchenko V, Bird NH, Lukeš J, Lemaitre B, Perlman SJ.

MBio. 2015 Sep 15;6(5):e01356-15. doi: 10.1128/mBio.01356-15.

13.

Maternal transmission, sex ratio distortion, and mitochondria.

Perlman SJ, Hodson CN, Hamilton PT, Opit GP, Gowen BE.

Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):10162-8. doi: 10.1073/pnas.1421391112. Epub 2015 Apr 13. Review.

14.

Characterization of a thermophilic bacteriophage of Geobacillus kaustophilus.

Marks TJ, Hamilton PT.

Arch Virol. 2014 Oct;159(10):2771-5. doi: 10.1007/s00705-014-2101-8. Epub 2014 May 6.

PMID:
24796554
15.

Host defense via symbiosis in Drosophila.

Hamilton PT, Perlman SJ.

PLoS Pathog. 2013;9(12):e1003808. doi: 10.1371/journal.ppat.1003808. Epub 2013 Dec 26. Review. No abstract available.

16.

Cooperative Learning through Team-Based Projects in the Biotechnology Industry.

Luginbuhl SC, Hamilton PT.

J Microbiol Biol Educ. 2013 Dec 2;14(2):221-9. doi: 10.1128/jmbe.v14i2.608. eCollection 2013.

17.

Transcriptional responses in a Drosophila defensive symbiosis.

Hamilton PT, Leong JS, Koop BF, Perlman SJ.

Mol Ecol. 2014 Mar;23(6):1558-70. doi: 10.1111/mec.12603. Epub 2013 Dec 28.

PMID:
24274471
18.

Improved bone morphogenetic protein-2 retention in an injectable collagen matrix using bifunctional peptides.

Hamilton PT, Jansen MS, Ganesan S, Benson RE, Hyde-Deruyscher R, Beyer WF, Gile JC, Nair SA, Hodges JA, Grøn H.

PLoS One. 2013 Aug 8;8(8):e70715. doi: 10.1371/journal.pone.0070715. eCollection 2013.

19.

Infectious adaptation: potential host range of a defensive endosymbiont in Drosophila.

Haselkorn TS, Cockburn SN, Hamilton PT, Perlman SJ, Jaenike J.

Evolution. 2013 Apr;67(4):934-45. doi: 10.1111/evo.12020. Epub 2012 Dec 24.

PMID:
23550746
20.

Dynamics of the continent-wide spread of a Drosophila defensive symbiont.

Cockburn SN, Haselkorn TS, Hamilton PT, Landzberg E, Jaenike J, Perlman SJ.

Ecol Lett. 2013 May;16(5):609-16. doi: 10.1111/ele.12087. Epub 2013 Mar 12.

PMID:
23517577
21.

Higher temperature variability increases the impact of Batrachochytrium dendrobatidis and shifts interspecific interactions in tadpole mesocosms.

Hamilton PT, Richardson JM, Govindarajulu P, Anholt BR.

Ecol Evol. 2012 Oct;2(10):2450-9. doi: 10.1002/ece3.369. Epub 2012 Aug 29.

22.

Preparing Science-Trained Professionals for the Biotechnology Industry: A Ten-Year Perspective on a Professional Science Master's Program.

Hamilton PT, Luginbuhl SC, Hyman M.

J Microbiol Biol Educ. 2012 May 3;13(1):39-44. doi: 10.1128/jmbe.v13i1.375. Print 2012.

23.

Intracellular expression of Peptide fusions for demonstration of protein essentiality in bacteria.

Benson RE, Gottlin EB, Christensen DJ, Hamilton PT.

Antimicrob Agents Chemother. 2003 Sep;47(9):2875-81.

24.

Identification and characterization of peptide probes directed against PKCalpha conformations.

Ashraf SS, Anderson E, Duke K, Hamilton PT, Fredericks Z.

J Pept Res. 2003 May;61(5):263-73.

PMID:
12662360
25.

Identification of enzyme inhibitors from phage-displayed combinatorial peptide libraries.

Kay BK, Hamilton PT.

Comb Chem High Throughput Screen. 2001 Nov;4(7):535-43.

PMID:
11562258
26.

Phage display for target-based antibacterial drug discovery.

Christensen DJ, Gottlin EB, Benson RE, Hamilton PT.

Drug Discov Today. 2001 Jul 1;6(14):721-727.

PMID:
11445463
27.

Detection of small-molecule enzyme inhibitors with peptides isolated from phage-displayed combinatorial peptide libraries.

Hyde-DeRuyscher R, Paige LA, Christensen DJ, Hyde-DeRuyscher N, Lim A, Fredericks ZL, Kranz J, Gallant P, Zhang J, Rocklage SM, Fowlkes DM, Wendler PA, Hamilton PT.

Chem Biol. 2000 Jan;7(1):17-25.

28.

Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: discovery of peptide antagonists of estrogen receptors alpha and beta.

Chang Cy, Norris JD, Grøn H, Paige LA, Hamilton PT, Kenan DJ, Fowlkes D, McDonnell DP.

Mol Cell Biol. 1999 Dec;19(12):8226-39.

29.

Peptide antagonists of the human estrogen receptor.

Norris JD, Paige LA, Christensen DJ, Chang CY, Huacani MR, Fan D, Hamilton PT, Fowlkes DM, McDonnell DP.

Science. 1999 Jul 30;285(5428):744-6.

30.

Estrogen receptor (ER) modulators each induce distinct conformational changes in ER alpha and ER beta.

Paige LA, Christensen DJ, Grøn H, Norris JD, Gottlin EB, Padilla KM, Chang CY, Ballas LM, Hamilton PT, McDonnell DP, Fowlkes DM.

Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3999-4004.

31.

Applying genetic engineering to the structural analysis of proteins.

Hamilton PT.

Pharm Biotechnol. 1995;7:329-50. Review.

PMID:
8564022
32.

Nucleotide sequence of the major outer membrane protein gene from Chlamydia trachomatis serovar H.

Hamilton PT, Malinowski DP.

Nucleic Acids Res. 1989 Oct 25;17(20):8366. No abstract available.

33.

A hydrogenase-linked gene in Methanobacterium thermoautotrophicum strain delta H encodes a polyferredoxin.

Reeve JN, Beckler GS, Cram DS, Hamilton PT, Brown JW, Krzycki JA, Kolodziej AF, Alex L, Orme-Johnson WH, Walsh CT.

Proc Natl Acad Sci U S A. 1989 May;86(9):3031-5.

34.
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36.

Beginning genetics with methanogens.

Reeve JN, Trun NJ, Hamilton PT.

Basic Life Sci. 1982;19:233-44. No abstract available.

PMID:
6175305

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