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Items: 1 to 50 of 134

1.

Neuroendocrine drivers of risk and resilience: The influence of metabolism & mitochondria.

Turkson S, Kloster A, Hamilton PJ, Neigh GN.

Front Neuroendocrinol. 2019 Jul 6:100770. doi: 10.1016/j.yfrne.2019.100770. [Epub ahead of print] Review.

PMID:
31288042
2.

Epigenetics and addiction.

Hamilton PJ, Nestler EJ.

Curr Opin Neurobiol. 2019 Jun 27;59:128-136. doi: 10.1016/j.conb.2019.05.005. [Epub ahead of print] Review.

PMID:
31255844
3.

Stereotaxic Surgery and Viral Delivery of Zinc-Finger Epigenetic Editing Tools in Rodent Brain.

Hamilton PJ, Lim CJ, Nestler EJ, Heller EA.

Methods Mol Biol. 2018;1867:229-238. doi: 10.1007/978-1-4939-8799-3_17.

4.

Transcriptional and physiological adaptations in nucleus accumbens somatostatin interneurons that regulate behavioral responses to cocaine.

Ribeiro EA, Salery M, Scarpa JR, Calipari ES, Hamilton PJ, Ku SM, Kronman H, Purushothaman I, Juarez B, Heshmati M, Doyle M, Lardner C, Burek D, Strat A, Pirpinias S, Mouzon E, Han MH, Neve RL, Bagot RC, Kasarskis A, Koo JW, Nestler EJ.

Nat Commun. 2018 Aug 8;9(1):3149. doi: 10.1038/s41467-018-05657-9.

5.

Withdrawal from repeated morphine administration augments expression of the RhoA network in the nucleus accumbens to control synaptic structure.

Cahill ME, Browne CJ, Wang J, Hamilton PJ, Dong Y, Nestler EJ.

J Neurochem. 2018 Oct;147(1):84-98. doi: 10.1111/jnc.14563. Epub 2018 Sep 26.

PMID:
30071134
6.

Corrigendum: Sex-specific transcriptional signatures in human depression.

Labonté B, Engmann O, Purushothaman I, Menard C, Wang J, Tan C, Scarpa JR, Moy G, Loh YE, Cahill M, Lorsch ZS, Hamilton PJ, Calipari ES, Hodes GE, Issler O, Kronman H, Pfau M, Obradovic ALJ, Dong Y, Neve RL, Russo S, Kasarskis A, Tamminga C, Mechawar N, Turecki G, Zhang B, Shen L, Nestler EJ.

Nat Med. 2018 Apr 10;24(4):525. doi: 10.1038/nm0418-525d.

PMID:
29634684
7.

Estrogen receptor α drives pro-resilient transcription in mouse models of depression.

Lorsch ZS, Loh YE, Purushothaman I, Walker DM, Parise EM, Salery M, Cahill ME, Hodes GE, Pfau ML, Kronman H, Hamilton PJ, Issler O, Labonté B, Symonds AE, Zucker M, Zhang TY, Meaney MJ, Russo SJ, Shen L, Bagot RC, Nestler EJ.

Nat Commun. 2018 Mar 16;9(1):1116. doi: 10.1038/s41467-018-03567-4.

8.

Viral Expression of Epigenome Editing Tools in Rodent Brain Using Stereotaxic Surgery Techniques.

Hamilton PJ, Lim CJ, Nestler EJ, Heller EA.

Methods Mol Biol. 2018;1767:205-214. doi: 10.1007/978-1-4939-7774-1_10.

9.

Neuroepigenetic Editing.

Hamilton PJ, Lim CJ, Nestler EJ, Heller EA.

Methods Mol Biol. 2018;1767:113-136. doi: 10.1007/978-1-4939-7774-1_5. Review.

10.

Sex-specific transcriptional signatures in human depression.

Labonté B, Engmann O, Purushothaman I, Menard C, Wang J, Tan C, Scarpa JR, Moy G, Loh YE, Cahill M, Lorsch ZS, Hamilton PJ, Calipari ES, Hodes GE, Issler O, Kronman H, Pfau M, Obradovic ALJ, Dong Y, Neve RL, Russo S, Kazarskis A, Tamminga C, Mechawar N, Turecki G, Zhang B, Shen L, Nestler EJ.

Nat Med. 2017 Sep;23(9):1102-1111. doi: 10.1038/nm.4386. Epub 2017 Aug 21. Erratum in: Nat Med. 2018 Apr 10;24(4):525.

11.

Cocaine-Induced Chromatin Modifications Associate With Increased Expression and Three-Dimensional Looping of Auts2.

Engmann O, Labonté B, Mitchell A, Bashtrykov P, Calipari ES, Rosenbluh C, Loh YE, Walker DM, Burek D, Hamilton PJ, Issler O, Neve RL, Turecki G, Hurd Y, Chess A, Shen L, Mansuy I, Jeltsch A, Akbarian S, Nestler EJ.

Biol Psychiatry. 2017 Dec 1;82(11):794-805. doi: 10.1016/j.biopsych.2017.04.013. Epub 2017 May 5.

12.

Cell-Type-Specific Epigenetic Editing at the Fosb Gene Controls Susceptibility to Social Defeat Stress.

Hamilton PJ, Burek DJ, Lombroso SI, Neve RL, Robison AJ, Nestler EJ, Heller EA.

Neuropsychopharmacology. 2018 Jan;43(2):272-284. doi: 10.1038/npp.2017.88. Epub 2017 May 2.

13.

Targeted Epigenetic Remodeling of the Cdk5 Gene in Nucleus Accumbens Regulates Cocaine- and Stress-Evoked Behavior.

Heller EA, Hamilton PJ, Burek DD, Lombroso SI, Peña CJ, Neve RL, Nestler EJ.

J Neurosci. 2016 Apr 27;36(17):4690-7. doi: 10.1523/JNEUROSCI.0013-16.2016.

14.

Rare autism-associated variants implicate syntaxin 1 (STX1 R26Q) phosphorylation and the dopamine transporter (hDAT R51W) in dopamine neurotransmission and behaviors.

Cartier E, Hamilton PJ, Belovich AN, Shekar A, Campbell NG, Saunders C, Andreassen TF, Gether U, Veenstra-Vanderweele J, Sutcliffe JS, Ulery-Reynolds PG, Erreger K, Matthies HJ, Galli A.

EBioMedicine. 2015 Feb;2(2):135-146.

15.

Zn(2+) reverses functional deficits in a de novo dopamine transporter variant associated with autism spectrum disorder.

Hamilton PJ, Shekar A, Belovich AN, Christianson NB, Campbell NG, Sutcliffe JS, Galli A, Matthies HJ, Erreger K.

Mol Autism. 2015 Feb 24;6:8. doi: 10.1186/s13229-015-0002-7. eCollection 2015.

16.

SLC6A3 coding variant Ala559Val found in two autism probands alters dopamine transporter function and trafficking.

Bowton E, Saunders C, Reddy IA, Campbell NG, Hamilton PJ, Henry LK, Coon H, Sakrikar D, Veenstra-VanderWeele JM, Blakely RD, Sutcliffe J, Matthies HJ, Erreger K, Galli A.

Transl Psychiatry. 2014 Oct 14;4:e464. doi: 10.1038/tp.2014.90.

17.

Missense dopamine transporter mutations associate with adult parkinsonism and ADHD.

Hansen FH, Skjørringe T, Yasmeen S, Arends NV, Sahai MA, Erreger K, Andreassen TF, Holy M, Hamilton PJ, Neergheen V, Karlsborg M, Newman AH, Pope S, Heales SJ, Friberg L, Law I, Pinborg LH, Sitte HH, Loland C, Shi L, Weinstein H, Galli A, Hjermind LE, Møller LB, Gether U.

J Clin Invest. 2014 Jul;124(7):3107-20. doi: 10.1172/JCI73778. Epub 2014 Jun 9.

18.

PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein.

Hamilton PJ, Belovich AN, Khelashvili G, Saunders C, Erreger K, Javitch JA, Sitte HH, Weinstein H, Matthies HJG, Galli A.

Nat Chem Biol. 2014 Jul;10(7):582-589. doi: 10.1038/nchembio.1545. Epub 2014 Jun 1. Erratum in: Biol Psychiatry. 2017 Apr 15;81(8):728.

19.

Drosophila melanogaster: a novel animal model for the behavioral characterization of autism-associated mutations in the dopamine transporter gene.

Hamilton PJ, Campbell NG, Sharma S, Erreger K, Hansen FH, Saunders C, Belovich AN, Sahai MA, Cook EH, Gether U, McHaourab HS, Matthies HJ, Sutcliffe JS, Galli A.

Mol Psychiatry. 2013 Dec;18(12):1235. doi: 10.1038/mp.2013.157. No abstract available.

PMID:
24253181
20.

De novo mutation in the dopamine transporter gene associates dopamine dysfunction with autism spectrum disorder.

Hamilton PJ, Campbell NG, Sharma S, Erreger K, Herborg Hansen F, Saunders C, Belovich AN; NIH ARRA Autism Sequencing Consortium, Sahai MA, Cook EH, Gether U, McHaourab HS, Matthies HJ, Sutcliffe JS, Galli A.

Mol Psychiatry. 2013 Dec;18(12):1315-23. doi: 10.1038/mp.2013.102. Epub 2013 Aug 27.

21.

Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphate.

Buchmayer F, Schicker K, Steinkellner T, Geier P, Stübiger G, Hamilton PJ, Jurik A, Stockner T, Yang JW, Montgomery T, Holy M, Hofmaier T, Kudlacek O, Matthies HJ, Ecker GF, Bochkov V, Galli A, Boehm S, Sitte HH.

Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11642-7. doi: 10.1073/pnas.1220552110. Epub 2013 Jun 24.

22.

Attention deficit/hyperactivity disorder-derived coding variation in the dopamine transporter disrupts microdomain targeting and trafficking regulation.

Sakrikar D, Mazei-Robison MS, Mergy MA, Richtand NW, Han Q, Hamilton PJ, Bowton E, Galli A, Veenstra-Vanderweele J, Gill M, Blakely RD.

J Neurosci. 2012 Apr 18;32(16):5385-97. doi: 10.1523/JNEUROSCI.6033-11.2012. Erratum in: J Neurosci. 2012 Oct 31;32(44):15643.

23.

Reduced expression of the NMDA receptor-interacting protein SynGAP causes behavioral abnormalities that model symptoms of Schizophrenia.

Guo X, Hamilton PJ, Reish NJ, Sweatt JD, Miller CA, Rumbaugh G.

Neuropsychopharmacology. 2009 Jun;34(7):1659-72. doi: 10.1038/npp.2008.223. Epub 2009 Jan 14.

24.

Guidelines on the management of massive blood loss.

British Committee for Standards in Haematology, Stainsby D, MacLennan S, Thomas D, Isaac J, Hamilton PJ.

Br J Haematol. 2006 Dec;135(5):634-41. No abstract available.

PMID:
17107347
25.

Dietary folate deficiency with normal red cell folate and circulating blasts.

Stark GL, Hamilton PJ.

J Clin Pathol. 2003 Apr;56(4):313-5.

26.

The dangers of iron overload in pyruvate kinase deficiency.

Marshall SR, Saunders PW, Hamilton PJ, Taylor PR.

Br J Haematol. 2003 Mar;120(6):1090-1. No abstract available.

PMID:
12648084
27.

Erythroleukaemia in the north of England: a population based study.

Wells AW, Bown N, Reid MM, Hamilton PJ, Jackson GH, Taylor PR.

J Clin Pathol. 2001 Aug;54(8):608-12.

28.

Management of massive blood loss: a template guideline.

Stainsby D, MacLennan S, Hamilton PJ.

Br J Anaesth. 2000 Sep;85(3):487-91. Review.

29.

Acquired haemophilia complicating the remission of a patient with high grade non-Hodgkin's lymphoma treated by fludarabine.

Tiplady CW, Hamilton PJ, Galloway MJ.

Clin Lab Haematol. 2000 Jun;22(3):163-5.

PMID:
10931166
30.

SPRs: confidence and experience in 'procedures'.

Hamilton PJ, Reid MM.

J R Coll Physicians Lond. 1998 Nov-Dec;32(6):589. No abstract available.

PMID:
9881319
31.

Test-driving the Internet: a hospital collaborative pilot project.

Coble C, Bossen MD, Hamilton PJ.

Bull Med Libr Assoc. 1998 Jul;86(3):410-2. No abstract available.

32.

Upper limb thrombosis associated with assisted conception treatment.

Stewart JA, Hamilton PJ, Murdoch AP.

Hum Reprod. 1997 Oct;12(10):2174-5.

PMID:
9402277
33.

Thromboembolic disease associated with ovarian stimulation and assisted conception techniques.

Stewart JA, Hamilton PJ, Murdoch AP.

Hum Reprod. 1997 Oct;12(10):2167-73. Review.

PMID:
9402276
34.

Low incidence of myelodysplastic syndrome following transplantation using autologous non-cryopreserved bone marrow.

Taylor PR, Jackson GH, Lennard AL, Hamilton PJ, Proctor SJ.

Leukemia. 1997 Oct;11(10):1650-3.

PMID:
9324284
35.

The use of an all oral chemotherapy (idarubicin and etoposide) in the treatment of acute myeloid leukaemia in the elderly: a report of toxicity and efficacy.

Jackson GH, Taylor PR, Iqbal A, Galloway MJ, Turner G, Haynes A, Hamilton PJ, Russell N, Proctor SJ.

Leukemia. 1997 Aug;11(8):1193-6.

PMID:
9264368
36.

The Alder-Reilly anomaly in association with the myelodysplastic syndrome.

Ghandi MK, Howard MR, Hamilton PJ.

Clin Lab Haematol. 1996 Mar;18(1):39-40.

PMID:
9118602
38.

Low frequency of myelodysplasia after autologous bone marrow transplantation.

Taylor P, Jackson GH, Lennard A, Hamilton PJ, Proctor SJ.

Lancet. 1995 May 13;345(8959):1248-9. No abstract available.

PMID:
7739340
39.

Role of target organ infection with cytomegalovirus in the pathogenesis of graft-versus-host disease.

Appleton AL, Sviland L, Peiris JS, Taylor CE, Wilkes J, Green MA, Pearson AD, Proctor SJ, Hamilton PJ, Cant AJ, et al.

Bone Marrow Transplant. 1995 Apr;15(4):557-61.

PMID:
7655381
40.
41.

Transfusion-associated graft-versus-host disease in fludarabine-treated B-chronic lymphocytic leukaemia.

Maung ZT, Wood AC, Jackson GH, Turner GE, Appleton AL, Hamilton PJ.

Br J Haematol. 1994 Nov;88(3):649-52.

PMID:
7819085
42.
43.

The relationship between bcl-2 expression and response to chemotherapy in acute leukaemia.

Maung ZT, MacLean FR, Reid MM, Pearson AD, Proctor SJ, Hamilton PJ, Hall AG.

Br J Haematol. 1994 Sep;88(1):105-9.

PMID:
7803231
44.

Assessing iron status in children with chronic renal failure on erythropoietin: which measurements should we use?

Morris KP, Watson S, Reid MM, Hamilton PJ, Coulthard MG.

Pediatr Nephrol. 1994 Feb;8(1):51-6.

PMID:
8142226
45.

Safe blood? Saving lives costs money.

Hamilton PJ.

BMJ. 1994 Jan 22;308(6923):273. No abstract available.

46.

Cytokine involvement in predicting clinical graft-versus-host disease in allogeneic bone marrow transplant recipients.

Dickinson AM, Sviland L, Hamilton PJ, Usher P, Taylor P, Jackson G, Dunn J, Proctor SJ.

Bone Marrow Transplant. 1994 Jan;13(1):65-70.

PMID:
8019455
48.

Prognostic importance of histological and immunopathological assessment of skin and rectal biopsies in patients with GVHD.

Sviland L, Pearson AD, Green MA, Eastham EJ, Hamilton PJ, Proctor SJ, Malcolm AJ.

Bone Marrow Transplant. 1993 Mar;11(3):215-8.

PMID:
8467285
49.

Acute lymphoblastic leukemia in patients aged 60 years and over: a population-based study of incidence and outcome.

Taylor PR, Reid MM, Bown N, Hamilton PJ, Proctor SJ.

Blood. 1992 Oct 1;80(7):1813-7.

50.

Immunopathology of early graft-versus-host disease--a prospective study of skin, rectum, and peripheral blood in allogeneic and autologous bone marrow transplant recipients.

Sviland L, Pearson AD, Green MA, Baker BD, Eastham EJ, Reid MM, Hamilton PJ, Proctor SJ, Malcolm AJ.

Transplantation. 1991 Dec;52(6):1029-36.

PMID:
1836284

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