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Items: 1 to 50 of 275

1.

Low prevalence red blood cell antigens: transfusions, babies, and changing demographics.

Hamilton JR.

Transfusion. 2020 Apr;60(4):659-662. doi: 10.1111/trf.15764. No abstract available.

PMID:
32246481
2.

Knocking out barriers to engineered cell activity.

Hamilton JR, Doudna JA.

Science. 2020 Feb 28;367(6481):976-977. doi: 10.1126/science.aba9844. Epub 2020 Feb 6. No abstract available.

PMID:
32029685
3.

Saline-indirect antiglobulin test.

Hamilton JR.

Immunohematology. 2019 Dec;35(4):156-158.

PMID:
31935333
4.

Targeting Antigen to the Surface of EVs Improves the In Vivo Immunogenicity of Human and Non-human Adenoviral Vaccines in Mice.

Bliss CM, Parsons AJ, Nachbagauer R, Hamilton JR, Cappuccini F, Ulaszewska M, Webber JP, Clayton A, Hill AVS, Coughlan L.

Mol Ther Methods Clin Dev. 2019 Dec 24;16:108-125. doi: 10.1016/j.omtm.2019.12.003. eCollection 2020 Mar 13.

5.

Using PAR4 Inhibition as an Anti-Thrombotic Approach: Why, How, and When?

Li S, Tarlac V, Hamilton JR.

Int J Mol Sci. 2019 Nov 11;20(22). pii: E5629. doi: 10.3390/ijms20225629. Review.

6.

Ultrasound-Guided Lateral Femoral Cutaneous Nerve Cryoneurolysis for Analgesia in Patients With Burns.

Finneran JJ, Swisher MW, Gabriel RA, Fiallo A, Hamilton JR, Lee JG, Ilfeld BM.

J Burn Care Res. 2020 Jan 30;41(1):224-227. doi: 10.1093/jbcr/irz192.

PMID:
31714578
7.

Suture Catheter for Rescue Perineural Catheter Placement When Unable to Position a Conventional Through-the-Needle Catheter: A Case Report.

Finneran JJ 4th, Gabriel RA, Swisher MW, Said E, Doan CN, Hamilton JR, Ilfeld BM.

A A Pract. 2019 Nov 1;13(9):338-341. doi: 10.1213/XAA.0000000000001075.

8.

DNA mismatch repair is required for the host innate response and controls cellular fate after influenza virus infection.

Chambers BS, Heaton BE, Rausch K, Dumm RE, Hamilton JR, Cherry S, Heaton NS.

Nat Microbiol. 2019 Nov;4(11):1964-1977. doi: 10.1038/s41564-019-0509-3. Epub 2019 Jul 29.

9.

Active Micropump-Mixer for Rapid Antiplatelet Drug Screening in Whole Blood.

Szydzik C, Brazilek RJ, Akbaridoust F, de Silva C, Moon M, Marusic I, Ooi ASH, Nandurkar HH, Hamilton JR, Mitchell A, Nesbitt WS.

Anal Chem. 2019 Aug 20;91(16):10830-10839. doi: 10.1021/acs.analchem.9b02486. Epub 2019 Aug 6.

PMID:
31343155
10.

Shared roles for Scl and Lyl1 in murine platelet production and function.

Chiu SK, Orive SL, Moon MJ, Saw J, Ellis S, Kile BT, Huang Y, Chacon D, Pimanda JE, Beck D, Hamilton JR, Tremblay CS, Curtis DJ.

Blood. 2019 Sep 5;134(10):826-835. doi: 10.1182/blood.2019896175. Epub 2019 Jul 12.

PMID:
31300405
11.

Albumin-indirect antiglobulin test.

Hamilton JR.

Immunohematology. 2019 Jun;35(2):63-64.

PMID:
31246490
12.

The mode of anesthesia influences outcome in mouse models of arterial thrombosis.

Sashindranath M, Sturgeon SA, French S, Craenmehr DDD, Selan C, Freddi S, Johnson C, Cody SH, Nesbitt WS, Hamilton JR, Nandurkar HH.

Res Pract Thromb Haemost. 2019 Feb 15;3(2):197-206. doi: 10.1002/rth2.12184. eCollection 2019 Apr.

13.

The PI 3-kinase PI3KC2α regulates mouse platelet membrane structure and function independently of membrane lipid composition.

Selvadurai MV, Brazilek RJ, Moon MJ, Rinckel JY, Eckly A, Gachet C, Meikle PJ, Nandurkar HH, Nesbitt WS, Hamilton JR.

FEBS Lett. 2019 Jan;593(1):88-96. doi: 10.1002/1873-3468.13295. Epub 2018 Nov 24.

14.

Characterization of the vibrational properties of copper difluoride anion and neutral ground states via direct and indirect photodetachment spectroscopy.

Lyle J, Chandramoulee SR, Hamilton JR, Traylor BA, Guasco TL, Jagau TC, Mabbs R.

J Chem Phys. 2018 Aug 28;149(8):084302. doi: 10.1063/1.5040122.

PMID:
30193472
15.

A function-blocking PAR4 antibody is markedly antithrombotic in the face of a hyperreactive PAR4 variant.

French SL, Thalmann C, Bray PF, Macdonald LE, Murphy AJ, Sleeman MW, Hamilton JR.

Blood Adv. 2018 Jun 12;2(11):1283-1293. doi: 10.1182/bloodadvances.2017015552.

16.

Structure and function of the open canalicular system - the platelet's specialized internal membrane network.

Selvadurai MV, Hamilton JR.

Platelets. 2018 Jun;29(4):319-325. doi: 10.1080/09537104.2018.1431388. Epub 2018 Feb 14. Review.

PMID:
29442528
17.

A Recombinant Antibody-Expressing Influenza Virus Delays Tumor Growth in a Mouse Model.

Hamilton JR, Vijayakumar G, Palese P.

Cell Rep. 2018 Jan 2;22(1):1-7. doi: 10.1016/j.celrep.2017.12.025.

18.

Drugs targeting protease-activated receptor-4 improve the anti-thrombotic therapeutic window.

French SL, Hamilton JR.

Ann Transl Med. 2017 Dec;5(23):464. doi: 10.21037/atm.2017.09.10. No abstract available.

19.

Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice.

He W, Chen CJ, Mullarkey CE, Hamilton JR, Wong CK, Leon PE, Uccellini MB, Chromikova V, Henry C, Hoffman KW, Lim JK, Wilson PC, Miller MS, Krammer F, Palese P, Tan GS.

Nat Commun. 2017 Oct 10;8(1):846. doi: 10.1038/s41467-017-00928-3.

20.

Perinatal lethality of Par4-/- mice delivered by primiparous dams reveals spontaneous bleeding in mice without platelet thrombin receptor function.

French SL, Hamilton JR.

Platelets. 2018 Mar;29(2):196-198. doi: 10.1080/09537104.2017.1349310. Epub 2017 Sep 29.

PMID:
28960148
21.

Inhibition of NMDA receptor function with an anti-GluN1-S2 antibody impairs human platelet function and thrombosis.

Green TN, Hamilton JR, Morel-Kopp MC, Zheng Z, Chen TT, Hearn JI, Sun PP, Flanagan JU, Young D, Barber PA, During MJ, Ward CM, Kalev-Zylinska ML.

Platelets. 2017 Dec;28(8):799-811. doi: 10.1080/09537104.2017.1280149. Epub 2017 Feb 21.

PMID:
28277064
22.

Humanizing the Protease-Activated Receptor (PAR) Expression Profile in Mouse Platelets by Knocking PAR1 into the Par3 Locus Reveals PAR1 Expression Is Not Tolerated in Mouse Platelets.

French SL, Paramitha AC, Moon MJ, Dickins RA, Hamilton JR.

PLoS One. 2016 Oct 27;11(10):e0165565. doi: 10.1371/journal.pone.0165565. eCollection 2016.

23.

Class II Phosphoinositide 3-Kinases as Novel Drug Targets.

Falasca M, Hamilton JR, Selvadurai M, Sundaram K, Adamska A, Thompson PE.

J Med Chem. 2017 Jan 12;60(1):47-65. doi: 10.1021/acs.jmedchem.6b00963. Epub 2016 Oct 21. Review.

PMID:
27644332
24.

Challenges and Opportunities in Protease-Activated Receptor Drug Development.

Hamilton JR, Trejo J.

Annu Rev Pharmacol Toxicol. 2017 Jan 6;57:349-373. doi: 10.1146/annurev-pharmtox-011613-140016. Epub 2016 Sep 9. Review.

PMID:
27618736
25.

Platelet and Erythrocyte Sources of S1P Are Redundant for Vascular Development and Homeostasis, but Both Rendered Essential After Plasma S1P Depletion in Anaphylactic Shock.

Gazit SL, Mariko B, Thérond P, Decouture B, Xiong Y, Couty L, Bonnin P, Baudrie V, Le Gall SM, Dizier B, Zoghdani N, Ransinan J, Hamilton JR, Gaussem P, Tharaux PL, Chun J, Coughlin SR, Bachelot-Loza C, Hla T, Ho-Tin-Noé B, Camerer E.

Circ Res. 2016 Sep 30;119(8):e110-26. doi: 10.1161/CIRCRESAHA.116.308929. Epub 2016 Aug 31.

26.

Discovery and antiplatelet activity of a selective PI3Kβ inhibitor (MIPS-9922).

Zheng Z, Pinson JA, Mountford SJ, Orive S, Schoenwaelder SM, Shackleford D, Powell A, Nelson EM, Hamilton JR, Jackson SP, Jennings IG, Thompson PE.

Eur J Med Chem. 2016 Oct 21;122:339-351. doi: 10.1016/j.ejmech.2016.06.010. Epub 2016 Jun 10.

PMID:
27387421
27.

Club cells surviving influenza A virus infection induce temporary nonspecific antiviral immunity.

Hamilton JR, Sachs D, Lim JK, Langlois RA, Palese P, Heaton NS.

Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):3861-6. doi: 10.1073/pnas.1522376113. Epub 2016 Mar 21.

28.

Combined deficiency of PI3KC2α and PI3KC2β reveals a nonredundant role for PI3KC2α in regulating mouse platelet structure and thrombus stability.

Petitjean C, Setiabakti NM, Mountford JK, Arthur JF, Ellis S, Hamilton JR.

Platelets. 2016 Jul;27(5):402-9. doi: 10.3109/09537104.2016.1145202. Epub 2016 Mar 4.

PMID:
26943229
29.

Inhibition of protease-activated receptor 4 impairs platelet procoagulant activity during thrombus formation in human blood.

French SL, Arthur JF, Lee H, Nesbitt WS, Andrews RK, Gardiner EE, Hamilton JR.

J Thromb Haemost. 2016 Aug;14(8):1642-54. doi: 10.1111/jth.13293. Epub 2016 Jun 22.

30.

Protease-activated receptor 4: from structure to function and back again.

French SL, Hamilton JR.

Br J Pharmacol. 2016 Oct;173(20):2952-65. doi: 10.1111/bph.13455. Epub 2016 Mar 10. Review.

31.

Thrombin-induced reactive oxygen species generation in platelets: A novel role for protease-activated receptor 4 and GPIbα.

Carrim N, Arthur JF, Hamilton JR, Gardiner EE, Andrews RK, Moran N, Berndt MC, Metharom P.

Redox Biol. 2015 Dec;6:640-647. doi: 10.1016/j.redox.2015.10.009. Epub 2015 Oct 28.

32.

Transamniotic stem cell therapy (TRASCET) mitigates bowel damage in a model of gastroschisis.

Feng C, Graham CD, Connors JP, Brazzo J 3rd, Pan AH, Hamilton JR, Zurakowski D, Fauza DO.

J Pediatr Surg. 2016 Jan;51(1):56-61. doi: 10.1016/j.jpedsurg.2015.10.011. Epub 2015 Oct 22.

PMID:
26548631
33.

Kidd blood group system: a review.

Hamilton JR.

Immunohematology. 2015;31(1):29-35. Review.

PMID:
26308468
34.

The class II PI 3-kinase, PI3KC2α, links platelet internal membrane structure to shear-dependent adhesive function.

Mountford JK, Petitjean C, Putra HW, McCafferty JA, Setiabakti NM, Lee H, Tønnesen LL, McFadyen JD, Schoenwaelder SM, Eckly A, Gachet C, Ellis S, Voss AK, Dickins RA, Hamilton JR, Jackson SP.

Nat Commun. 2015 Mar 17;6:6535. doi: 10.1038/ncomms7535.

35.

Human papillomavirus 16E6 and NFX1-123 potentiate Notch signaling and differentiation without activating cellular arrest.

Vliet-Gregg PA, Hamilton JR, Katzenellenbogen RA.

Virology. 2015 Apr;478:50-60. doi: 10.1016/j.virol.2015.02.002. Epub 2015 Feb 25.

36.

Class II but Not Second Class-Prospects for the Development of Class II PI3K Inhibitors.

Mountford SJ, Zheng Z, Sundaram K, Jennings IG, Hamilton JR, Thompson PE.

ACS Med Chem Lett. 2014 Sep 24;6(1):3-6. doi: 10.1021/ml500354e. eCollection 2015 Jan 8.

37.

Approval of the first protease-activated receptor antagonist: Rationale, development, significance, and considerations of a novel anti-platelet agent.

French SL, Arthur JF, Tran HA, Hamilton JR.

Blood Rev. 2015 May;29(3):179-89. doi: 10.1016/j.blre.2014.10.006. Epub 2014 Nov 6. Review.

PMID:
25467961
38.

Interoceptive ability predicts aversion to losses.

Sokol-Hessner P, Hartley CA, Hamilton JR, Phelps EA.

Cogn Emot. 2015;29(4):695-701. doi: 10.1080/02699931.2014.925426. Epub 2014 Jun 11.

39.

Differential signaling by protease-activated receptors: implications for therapeutic targeting.

Sidhu TS, French SL, Hamilton JR.

Int J Mol Sci. 2014 Apr 11;15(4):6169-83. doi: 10.3390/ijms15046169. Review.

40.

Ruling out bacteremia and bacterial meningitis in infants less than one month of age: is 48 hours of hospitalization necessary?

Fielding-Singh V, Hong DK, Harris SJ, Hamilton JR, Schroeder AR.

Hosp Pediatr. 2013 Oct;3(4):355-61. doi: 10.1542/hpeds.2013-0009.

41.

NFX1-123 and human papillomavirus 16E6 increase Notch expression in keratinocytes.

Vliet-Gregg PA, Hamilton JR, Katzenellenbogen RA.

J Virol. 2013 Dec;87(24):13741-50. doi: 10.1128/JVI.02582-13. Epub 2013 Oct 9.

42.

Rerecurrence 5 years after treatment of recurrent cutaneous basal cell and squamous cell carcinoma.

Hamilton JR, Parvataneni R, Stuart SE, Chren MM.

JAMA Dermatol. 2013 May;149(5):616-8. doi: 10.1001/jamadermatol.2013.3339. No abstract available.

43.

The PAR1 antagonist, SCH79797, alters platelet morphology and function independently of PARs.

Lee H, Hamilton JR.

Thromb Haemost. 2013 Jan;109(1):164-7. doi: 10.1160/TH12-06-0389. Epub 2012 Oct 23. No abstract available.

PMID:
23093354
44.

Halomonas johnsoniae: review of a medically underappreciated genus of growing human importance.

Stevens DA, Kim KK, Johnson N, Lee JS, Hamilton JR.

Am J Med Sci. 2013 May;345(5):335-8. doi: 10.1097/MAJ.0b013e31825600de. Review.

PMID:
22814360
45.

Durable effects of cognitive restructuring on conditioned fear.

Shurick AA, Hamilton JR, Harris LT, Roy AK, Gross JJ, Phelps EA.

Emotion. 2012 Dec;12(6):1393-7. doi: 10.1037/a0029143. Epub 2012 Jul 9.

46.

Pathologic shear triggers shedding of vascular receptors: a novel mechanism for down-regulation of platelet glycoprotein VI in stenosed coronary vessels.

Al-Tamimi M, Tan CW, Qiao J, Pennings GJ, Javadzadegan A, Yong AS, Arthur JF, Davis AK, Jing J, Mu FT, Hamilton JR, Jackson SP, Ludwig A, Berndt MC, Ward CM, Kritharides L, Andrews RK, Gardiner EE.

Blood. 2012 May 3;119(18):4311-20. doi: 10.1182/blood-2011-10-386607. Epub 2012 Mar 19.

PMID:
22431567
47.

Safety and efficacy of targeting platelet proteinase-activated receptors in combination with existing anti-platelet drugs as antithrombotics in mice.

Lee H, Sturgeon SA, Mountford JK, Jackson SP, Hamilton JR.

Br J Pharmacol. 2012 Aug;166(7):2188-97. doi: 10.1111/j.1476-5381.2012.01944.x.

48.

Physiology, pharmacology, and therapeutic potential of protease-activated receptors in vascular disease.

Lee H, Hamilton JR.

Pharmacol Ther. 2012 May;134(2):246-59. doi: 10.1016/j.pharmthera.2012.01.007. Epub 2012 Jan 30. Review.

PMID:
22327235
49.

The contribution of thrombin-induced platelet activation to thrombus growth is diminished under pathological blood shear conditions.

Lee H, Sturgeon SA, Jackson SP, Hamilton JR.

Thromb Haemost. 2012 Feb;107(2):328-37. doi: 10.1160/TH11-06-0418. Epub 2011 Dec 21.

PMID:
22187047
50.

Impact of a more restrictive approach to urinary tract imaging after febrile urinary tract infection.

Schroeder AR, Abidari JM, Kirpekar R, Hamilton JR, Kang YS, Tran V, Harris SJ.

Arch Pediatr Adolesc Med. 2011 Nov;165(11):1027-32. doi: 10.1001/archpediatrics.2011.178.

PMID:
22065183

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