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Items: 1 to 50 of 131

1.

Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development

Marx U, Akabane T, Andersson TB, Baker E, Beilmann M, Beken S, Brendler-Schwaab S, Cirit M, David R, Dehne EM, Durieux I, Ewart L, Fitzpatrick SC, Frey O, Fuchs F, Griffith LG, Hamilton GA, Hartung T, Hoeng J, Hogberg H, Hughes DJ, Ingber DE, Iskandar A, Kanamori T, Kojima H, Kuehnl J, Leist M, Li B, Loskill P, Mendrick DL, Neumann T, Pallocca G, Rusyn I, Smirnova L, Steger-Hartmann T, Tagle DA, Tonevitsky A, Tsyb S, Trapecar M, Van de Water B, Van den Eijnden-van Raaij J, Vulto P, Watanabe K, Wolf A, Zhou X, Roth A.

ALTEX. 2020 Feb 28. doi: 10.14573/altex.2001241. [Epub ahead of print]

2.

Robotic fluidic coupling and interrogation of multiple vascularized organ chips.

Novak R, Ingram M, Marquez S, Das D, Delahanty A, Herland A, Maoz BM, Jeanty SSF, Somayaji MR, Burt M, Calamari E, Chalkiadaki A, Cho A, Choe Y, Chou DB, Cronce M, Dauth S, Divic T, Fernandez-Alcon J, Ferrante T, Ferrier J, FitzGerald EA, Fleming R, Jalili-Firoozinezhad S, Grevesse T, Goss JA, Hamkins-Indik T, Henry O, Hinojosa C, Huffstater T, Jang KJ, Kujala V, Leng L, Mannix R, Milton Y, Nawroth J, Nestor BA, Ng CF, O'Connor B, Park TE, Sanchez H, Sliz J, Sontheimer-Phelps A, Swenor B, Thompson G 2nd, Touloumes GJ, Tranchemontagne Z, Wen N, Yadid M, Bahinski A, Hamilton GA, Levner D, Levy O, Przekwas A, Prantil-Baun R, Parker KK, Ingber DE.

Nat Biomed Eng. 2020 Jan 27. doi: 10.1038/s41551-019-0497-x. [Epub ahead of print]

PMID:
31988458
3.

Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model.

Kasendra M, Luc R, Yin J, Manatakis DV, Kulkarni G, Lucchesi C, Sliz J, Apostolou A, Sunuwar L, Obrigewitch J, Jang KJ, Hamilton GA, Donowitz M, Karalis K.

Elife. 2020 Jan 14;9. pii: e50135. doi: 10.7554/eLife.50135.

4.

Organs-on-Chips in Clinical Pharmacology: Putting the Patient Into the Center of Treatment Selection and Drug Development.

Peck RW, Hinojosa CD, Hamilton GA.

Clin Pharmacol Ther. 2020 Jan;107(1):181-185. doi: 10.1002/cpt.1688. Epub 2019 Nov 23. Review.

5.

Reproducing human and cross-species drug toxicities using a Liver-Chip.

Jang KJ, Otieno MA, Ronxhi J, Lim HK, Ewart L, Kodella KR, Petropolis DB, Kulkarni G, Rubins JE, Conegliano D, Nawroth J, Simic D, Lam W, Singer M, Barale E, Singh B, Sonee M, Streeter AJ, Manthey C, Jones B, Srivastava A, Andersson LC, Williams D, Park H, Barrile R, Sliz J, Herland A, Haney S, Karalis K, Ingber DE, Hamilton GA.

Sci Transl Med. 2019 Nov 6;11(517). pii: eaax5516. doi: 10.1126/scitranslmed.aax5516.

PMID:
31694927
6.

MacroH2A1 Regulation of Poly(ADP-Ribose) Synthesis and Stability Prevents Necrosis and Promotes DNA Repair.

Ruiz PD, Hamilton GA, Park JW, Gamble MJ.

Mol Cell Biol. 2019 Dec 11;40(1). pii: e00230-19. doi: 10.1128/MCB.00230-19. Print 2019 Dec 11.

7.

Integrated in vitro models for hepatic safety and metabolism: evaluation of a human Liver-Chip and liver spheroid.

Foster AJ, Chouhan B, Regan SL, Rollison H, Amberntsson S, Andersson LC, Srivastava A, Darnell M, Cairns J, Lazic SE, Jang KJ, Petropolis DB, Kodella K, Rubins JE, Williams D, Hamilton GA, Ewart L, Morgan P.

Arch Toxicol. 2019 Apr;93(4):1021-1037. doi: 10.1007/s00204-019-02427-4. Epub 2019 Mar 26.

PMID:
30915487
8.

Introducing an automated high content confocal imaging approach for Organs-on-Chips.

Peel S, Corrigan AM, Ehrhardt B, Jang KJ, Caetano-Pinto P, Boeckeler M, Rubins JE, Kodella K, Petropolis DB, Ronxhi J, Kulkarni G, Foster AJ, Williams D, Hamilton GA, Ewart L.

Lab Chip. 2019 Jan 29;19(3):410-421. doi: 10.1039/c8lc00829a.

PMID:
30663729
9.

Optimizing drug discovery by Investigative Toxicology: Current and future trends.

Beilmann M, Boonen H, Czich A, Dear G, Hewitt P, Mow T, Newham P, Oinonen T, Pognan F, Roth A, Valentin JP, Van Goethem F, Weaver RJ, Birk B, Boyer S, Caloni F, Chen AE, Corvi R, Cronin MTD, Daneshian M, Ewart LC, Fitzgerald RE, Hamilton GA, Hartung T, Kangas JD, Kramer NI, Leist M, Marx U, Polak S, Rovida C, Testai E, Van der Water B, Vulto P, Steger-Hartmann T.

ALTEX. 2019;36(2):289-313. doi: 10.14573/altex.1808181. Epub 2018 Dec 20.

10.

Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips.

Workman MJ, Gleeson JP, Troisi EJ, Estrada HQ, Kerns SJ, Hinojosa CD, Hamilton GA, Targan SR, Svendsen CN, Barrett RJ.

Cell Mol Gastroenterol Hepatol. 2017 Dec 29;5(4):669-677.e2. doi: 10.1016/j.jcmgh.2017.12.008. eCollection 2018.

11.

Human iPSC-Derived Endothelial Cells and Microengineered Organ-Chip Enhance Neuronal Development.

Sances S, Ho R, Vatine G, West D, Laperle A, Meyer A, Godoy M, Kay PS, Mandefro B, Hatata S, Hinojosa C, Wen N, Sareen D, Hamilton GA, Svendsen CN.

Stem Cell Reports. 2018 Apr 10;10(4):1222-1236. doi: 10.1016/j.stemcr.2018.02.012. Epub 2018 Mar 22.

12.

Organ-on-Chip Recapitulates Thrombosis Induced by an anti-CD154 Monoclonal Antibody: Translational Potential of Advanced Microengineered Systems.

Barrile R, van der Meer AD, Park H, Fraser JP, Simic D, Teng F, Conegliano D, Nguyen J, Jain A, Zhou M, Karalis K, Ingber DE, Hamilton GA, Otieno MA.

Clin Pharmacol Ther. 2018 Dec;104(6):1240-1248. doi: 10.1002/cpt.1054. Epub 2018 Apr 30.

PMID:
29484632
13.

Arthroscopic-Assisted Open Reduction Internal Fixation.

Hamilton GA, Doyle MD, Castellucci-Garza FM.

Clin Podiatr Med Surg. 2018 Apr;35(2):199-221. doi: 10.1016/j.cpm.2017.12.004. Epub 2018 Jan 2. Review.

PMID:
29482790
14.

Minimally Invasive Plate Osteosynthesis for Treatment of Ankle Fractures in High-Risk Patients.

Bazarov I, Kim J, Richey JM, Dickinson JD, Hamilton GA.

J Foot Ankle Surg. 2018 May - Jun;57(3):494-500. doi: 10.1053/j.jfas.2017.11.004. Epub 2018 Feb 2.

PMID:
29398510
15.

Primary Human Lung Alveolus-on-a-chip Model of Intravascular Thrombosis for Assessment of Therapeutics.

Jain A, Barrile R, van der Meer AD, Mammoto A, Mammoto T, De Ceunynck K, Aisiku O, Otieno MA, Louden CS, Hamilton GA, Flaumenhaft R, Ingber DE.

Clin Pharmacol Ther. 2018 Feb;103(2):332-340. doi: 10.1002/cpt.742. Epub 2017 Jul 14.

16.

Retrograde Extrusion of Coronary Thrombus During Urgent Aortocoronary Bypass Surgery: A Case Report.

Mizubuti GB, Koumpan Y, Hamilton GA, Phelan R, Ho AMH, Tanzola RC, Wang LTS.

A A Case Rep. 2017 May 15;8(10):268-271. doi: 10.1213/XAA.0000000000000489.

PMID:
28252540
17.

Assessment of whole blood thrombosis in a microfluidic device lined by fixed human endothelium.

Jain A, van der Meer AD, Papa AL, Barrile R, Lai A, Schlechter BL, Otieno MA, Louden CS, Hamilton GA, Michelson AD, Frelinger AL 3rd, Ingber DE.

Biomed Microdevices. 2016 Aug;18(4):73. doi: 10.1007/s10544-016-0095-6.

18.

Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro.

Benam KH, Villenave R, Lucchesi C, Varone A, Hubeau C, Lee HH, Alves SE, Salmon M, Ferrante TC, Weaver JC, Bahinski A, Hamilton GA, Ingber DE.

Nat Methods. 2016 Feb;13(2):151-7. doi: 10.1038/nmeth.3697. Epub 2015 Dec 21.

PMID:
26689262
19.

Identification and Optimization of Benzimidazole Sulfonamides as Orally Bioavailable Sphingosine 1-Phosphate Receptor 1 Antagonists with in Vivo Activity.

Hennessy EJ, Oza V, Adam A, Byth K, Castriotta L, Grewal G, Hamilton GA, Kamhi VM, Lewis P, Li D, Lyne P, Öster L, Rooney MT, Saeh JC, Sha L, Su Q, Wen S, Xue Y, Yang B.

J Med Chem. 2015 Sep 10;58(17):7057-75. doi: 10.1021/acs.jmedchem.5b01078. Epub 2015 Aug 26.

PMID:
26291341
20.

Measuring direct current trans-epithelial electrical resistance in organ-on-a-chip microsystems.

Odijk M, van der Meer AD, Levner D, Kim HJ, van der Helm MW, Segerink LI, Frimat JP, Hamilton GA, Ingber DE, van den Berg A.

Lab Chip. 2015 Feb 7;15(3):745-52. doi: 10.1039/c4lc01219d.

PMID:
25427650
21.

Effects of the lapidus arthrodesis and chevron bunionectomy on plantar forefoot pressures.

King CM, Hamilton GA, Ford LA.

J Foot Ankle Surg. 2014 Jul-Aug;53(4):415-9. doi: 10.1053/j.jfas.2013.08.007.

PMID:
24958073
22.

Microfabrication of human organs-on-chips.

Huh D, Kim HJ, Fraser JP, Shea DE, Khan M, Bahinski A, Hamilton GA, Ingber DE.

Nat Protoc. 2013 Nov;8(11):2135-57. doi: 10.1038/nprot.2013.137. Epub 2013 Oct 10.

PMID:
24113786
23.

Clear castable polyurethane elastomer for fabrication of microfluidic devices.

Domansky K, Leslie DC, McKinney J, Fraser JP, Sliz JD, Hamkins-Indik T, Hamilton GA, Bahinski A, Ingber DE.

Lab Chip. 2013 Oct 7;13(19):3956-64. doi: 10.1039/c3lc50558h.

24.

Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment.

Jang KJ, Mehr AP, Hamilton GA, McPartlin LA, Chung S, Suh KY, Ingber DE.

Integr Biol (Camb). 2013 Sep;5(9):1119-29. doi: 10.1039/c3ib40049b.

PMID:
23644926
25.

Sequential oxidations of thiolates and the cobalt metallocenter in a synthetic metallopeptide: implications for the biosynthesis of nitrile hydratase.

Dutta A, Flores M, Roy S, Schmitt JC, Hamilton GA, Hartnett HE, Shearer JM, Jones AK.

Inorg Chem. 2013 May 6;52(9):5236-45. doi: 10.1021/ic400171z. Epub 2013 Apr 15.

26.

Bioavailability of nanoparticulate hematite to Arabidopsis thaliana.

Marusenko Y, Shipp J, Hamilton GA, Morgan JL, Keebaugh M, Hill H, Dutta A, Zhuo X, Upadhyay N, Hutchings J, Herckes P, Anbar AD, Shock E, Hartnett HE.

Environ Pollut. 2013 Mar;174:150-6. doi: 10.1016/j.envpol.2012.11.020. Epub 2012 Dec 20.

PMID:
23262070
27.

A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice.

Huh D, Leslie DC, Matthews BD, Fraser JP, Jurek S, Hamilton GA, Thorneloe KS, McAlexander MA, Ingber DE.

Sci Transl Med. 2012 Nov 7;4(159):159ra147. doi: 10.1126/scitranslmed.3004249. Erratum in: Sci Transl Med. 2018 Jul 11;10(449):.

28.

Construction of heterometallic clusters in a small peptide scaffold as [NiFe]-hydrogenase models: development of a synthetic methodology.

Dutta A, Hamilton GA, Hartnett HE, Jones AK.

Inorg Chem. 2012 Sep 17;51(18):9580-8. doi: 10.1021/ic2026818. Epub 2012 Aug 27.

PMID:
22924594
29.

A mini-microscope for in situ monitoring of cells.

Kim SB, Koo KI, Bae H, Dokmeci MR, Hamilton GA, Bahinski A, Kim SM, Ingber DE, Khademhosseini A.

Lab Chip. 2012 Oct 21;12(20):3976-82.

30.

Association between ankle fractures and obesity.

King CM, Hamilton GA, Cobb M, Carpenter D, Ford LA.

J Foot Ankle Surg. 2012 Sep-Oct;51(5):543-7. doi: 10.1053/j.jfas.2012.05.016. Epub 2012 Jul 11.

PMID:
22789485
31.

End-stage hallux rigidus: cheilectomy, implant, or arthrodesis?

Peace RA, Hamilton GA.

Clin Podiatr Med Surg. 2012 Jul;29(3):341-53. doi: 10.1016/j.cpm.2012.04.002. Epub 2012 May 17.

PMID:
22727376
32.

Microengineered physiological biomimicry: organs-on-chips.

Huh D, Torisawa YS, Hamilton GA, Kim HJ, Ingber DE.

Lab Chip. 2012 Jun 21;12(12):2156-64. doi: 10.1039/c2lc40089h. Epub 2012 May 3. Review.

PMID:
22555377
33.

Complications after open reduction and internal fixation of ankle fractures in the elderly.

Lynde MJ, Sautter T, Hamilton GA, Schuberth JM.

Foot Ankle Surg. 2012 Jun;18(2):103-7. doi: 10.1016/j.fas.2011.03.010. Epub 2011 Apr 30.

PMID:
22443995
34.

Complications associated with foot and ankle arthroscopy.

Deng DF, Hamilton GA, Lee M, Rush S, Ford LA, Patel S.

J Foot Ankle Surg. 2012 May-Jun;51(3):281-4. doi: 10.1053/j.jfas.2011.11.011. Epub 2011 Dec 20.

PMID:
22188904
35.

From 3D cell culture to organs-on-chips.

Huh D, Hamilton GA, Ingber DE.

Trends Cell Biol. 2011 Dec;21(12):745-54. doi: 10.1016/j.tcb.2011.09.005. Epub 2011 Oct 25. Review.

36.

Clinical decision making of nurses working in hospital settings.

Bjørk IT, Hamilton GA.

Nurs Res Pract. 2011;2011:524918. doi: 10.1155/2011/524918. Epub 2011 Sep 28.

37.

Arthroscopically assisted treatment of ankle injuries.

Gumann G, Hamilton GA.

Clin Podiatr Med Surg. 2011 Jun;28(3):523-38. doi: 10.1016/j.cpm.2011.04.002. Epub 2011 Jun 25. Review.

PMID:
21777783
38.

Radiographic outcomes of adult acquired flatfoot corrected by medial column arthrodesis with or without a medializing calcaneal osteotomy.

Jordan TH, Rush SM, Hamilton GA, Ford LA.

J Foot Ankle Surg. 2011 Mar-Apr;50(2):176-81. doi: 10.1053/j.jfas.2010.12.008.

PMID:
21354002
39.

Effects of a computer-supported interactive tailored patient assessment tool on patient care, symptom distress, and patients' need for symptom management support: a randomized clinical trial.

Ruland CM, Holte HH, Røislien J, Heaven C, Hamilton GA, Kristiansen J, Sandbaek H, Kvaløy SO, Hasund L, Ellison MC.

J Am Med Inform Assoc. 2010 Jul-Aug;17(4):403-10. doi: 10.1136/jamia.2010.005660.

40.

The long-term lived experience of patients with implantable cardioverter defibrillators.

Flanagan JM, Carroll DL, Hamilton GA.

Medsurg Nurs. 2010 Mar-Apr;19(2):113-9. No abstract available.

PMID:
20476522
41.

First metatarsophalangeal joint arthrodesis and revision arthrodesis.

Hamilton GA, Ford LA, Patel S.

Clin Podiatr Med Surg. 2009 Jul;26(3):459-73, Table of Contents. doi: 10.1016/j.cpm.2009.03.010.

PMID:
19505644
42.

Procedure selection for hallux valgus.

Ford LA, Hamilton GA.

Clin Podiatr Med Surg. 2009 Jul;26(3):395-407, Table of Contents. doi: 10.1016/j.cpm.2009.03.005.

PMID:
19505640
43.

Evaluation of multiple in vitro systems for assessment of CYP3A4 induction in drug discovery: human hepatocytes, pregnane X receptor reporter gene, and Fa2N-4 and HepaRG cells.

McGinnity DF, Zhang G, Kenny JR, Hamilton GA, Otmani S, Stams KR, Haney S, Brassil P, Stresser DM, Riley RJ.

Drug Metab Dispos. 2009 Jun;37(6):1259-68. doi: 10.1124/dmd.109.026526. Epub 2009 Mar 23.

PMID:
19307295
44.

The effect of the Lapidus arthrodesis on the medial longitudinal arch: a radiographic review.

Avino A, Patel S, Hamilton GA, Ford LA.

J Foot Ankle Surg. 2008 Nov-Dec;47(6):510-4. doi: 10.1053/j.jfas.2008.06.008. Epub 2008 Jul 31.

PMID:
19239859
45.

Mesenchymal stem cell allograft in revision foot and ankle surgery: a clinical and radiographic analysis.

Rush SM, Hamilton GA, Ackerson LM.

J Foot Ankle Surg. 2009 Mar-Apr;48(2):163-9. doi: 10.1053/j.jfas.2008.12.008.

PMID:
19232968
46.

Talus fractures: surgical principles.

Rush SM, Jennings M, Hamilton GA.

Clin Podiatr Med Surg. 2009 Jan;26(1):91-103. doi: 10.1016/j.cpm.2008.09.007. Review.

PMID:
19121756
47.

The complexity of symptoms and problems experienced in children with cancer: a review of the literature.

Ruland CM, Hamilton GA, Schjødt-Osmo B.

J Pain Symptom Manage. 2009 Mar;37(3):403-18. doi: 10.1016/j.jpainsymman.2008.03.009. Epub 2008 Aug 9. Review.

48.

Rates of revision surgery using Chevron-Austin osteotomy, Lapidus arthrodesis, and closing base wedge osteotomy for correction of hallux valgus deformity.

Lagaay PM, Hamilton GA, Ford LA, Williams ME, Rush SM, Schuberth JM.

J Foot Ankle Surg. 2008 Jul-Aug;47(4):267-72. doi: 10.1053/j.jfas.2008.03.002. Epub 2008 May 9.

PMID:
18590886
49.
50.

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