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Items: 21

1.

A sweet alternative: maintaining M2 macrophage polarization.

Hamers AAJ, Pillai AB.

Sci Immunol. 2018 Nov 2;3(29). pii: eaav7759. doi: 10.1126/sciimmunol.aav7759.

PMID:
30389801
2.

Nur77 variants solely comprising the amino-terminal domain activate hypoxia-inducible factor-1α and affect bone marrow homeostasis in mice and humans.

Koenis DS, Medzikovic L, Vos M, Beldman TJ, van Loenen PB, van Tiel CM, Hamers AAJ, Otermin Rubio I, de Waard V, de Vries CJM.

J Biol Chem. 2018 Sep 28;293(39):15070-15083. doi: 10.1074/jbc.RA118.002720. Epub 2018 Aug 15.

PMID:
30111591
3.

Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry.

Winkels H, Ehinger E, Vassallo M, Buscher K, Dinh HQ, Kobiyama K, Hamers AAJ, Cochain C, Vafadarnejad E, Saliba AE, Zernecke A, Pramod AB, Ghosh AK, Anto Michel N, Hoppe N, Hilgendorf I, Zirlik A, Hedrick CC, Ley K, Wolf D.

Circ Res. 2018 Jun 8;122(12):1675-1688. doi: 10.1161/CIRCRESAHA.117.312513. Epub 2018 Mar 15.

PMID:
29545366
4.

Human Blood Monocyte Subsets: A New Gating Strategy Defined Using Cell Surface Markers Identified by Mass Cytometry.

Thomas GD, Hamers AAJ, Nakao C, Marcovecchio P, Taylor AM, McSkimming C, Nguyen AT, McNamara CA, Hedrick CC.

Arterioscler Thromb Vasc Biol. 2017 Aug;37(8):1548-1558. doi: 10.1161/ATVBAHA.117.309145. Epub 2017 Jun 8.

5.

Impact of the B Cell Growth Factor APRIL on the Qualitative and Immunological Characteristics of Atherosclerotic Plaques.

Bernelot Moens SJ, van Leuven SI, Zheng KH, Havik SR, Versloot MV, van Duivenvoorde LM, Hahne M, Stroes ES, Baeten DL, Hamers AA.

PLoS One. 2016 Nov 7;11(11):e0164690. doi: 10.1371/journal.pone.0164690. eCollection 2016.

6.

Deleting an Nr4a1 Super-Enhancer Subdomain Ablates Ly6Clow Monocytes while Preserving Macrophage Gene Function.

Thomas GD, Hanna RN, Vasudevan NT, Hamers AA, Romanoski CE, McArdle S, Ross KD, Blatchley A, Yoakum D, Hamilton BA, Mikulski Z, Jain MK, Glass CK, Hedrick CC.

Immunity. 2016 Nov 15;45(5):975-987. doi: 10.1016/j.immuni.2016.10.011. Epub 2016 Nov 1.

7.

Multiple pathway assessment to predict anti-atherogenic efficacy of drugs targeting macrophages in atherosclerotic plaques.

Alaarg A, Zheng KH, van der Valk FM, da Silva AE, Versloot M, van Ufford LC, Schulte DM, Storm G, Metselaar JM, Stroes ES, Hamers AA.

Vascul Pharmacol. 2016 Jul;82:51-9. doi: 10.1016/j.vph.2016.04.006. Epub 2016 May 14.

PMID:
27189780
8.

Liposomal prednisolone promotes macrophage lipotoxicity in experimental atherosclerosis.

van der Valk FM, Schulte DM, Meiler S, Tang J, Zheng KH, Van den Bossche J, Seijkens T, Laudes M, de Winther M, Lutgens E, Alaarg A, Metselaar JM, Dallinga-Thie GM, Mulder WJ, Stroes ES, Hamers AA.

Nanomedicine. 2016 Aug;12(6):1463-70. doi: 10.1016/j.nano.2016.02.022. Epub 2016 Mar 23.

PMID:
27015770
9.

Nur77-deficiency in bone marrow-derived macrophages modulates inflammatory responses, extracellular matrix homeostasis, phagocytosis and tolerance.

Hamers AA, Argmann C, Moerland PD, Koenis DS, Marinković G, Sokolović M, de Vos AF, de Vries CJ, van Tiel CM.

BMC Genomics. 2016 Mar 1;17:162. doi: 10.1186/s12864-016-2469-9.

10.

Interferon-β promotes macrophage foam cell formation by altering both cholesterol influx and efflux mechanisms.

Boshuizen MC, Hoeksema MA, Neele AE, van der Velden S, Hamers AA, Van den Bossche J, Lutgens E, de Winther MP.

Cytokine. 2016 Jan;77:220-6. doi: 10.1016/j.cyto.2015.09.016. Epub 2015 Oct 1.

PMID:
26427927
11.

Deficiency of Nuclear Receptor Nur77 Aggravates Mouse Experimental Colitis by Increased NFκB Activity in Macrophages.

Hamers AA, van Dam L, Teixeira Duarte JM, Vos M, Marinković G, van Tiel CM, Meijer SL, van Stalborch AM, Huveneers S, Te Velde AA, de Jonge WJ, de Vries CJ.

PLoS One. 2015 Aug 4;10(8):e0133598. doi: 10.1371/journal.pone.0133598. eCollection 2015.

12.

6-Mercaptopurine reduces cytokine and Muc5ac expression involving inhibition of NFκB activation in airway epithelial cells.

Kurakula K, Hamers AA, van Loenen P, de Vries CJ.

Respir Res. 2015 Jun 19;16:73. doi: 10.1186/s12931-015-0236-0.

13.

Myeloid A disintegrin and metalloproteinase domain 10 deficiency modulates atherosclerotic plaque composition by shifting the balance from inflammation toward fibrosis.

van der Vorst EP, Jeurissen M, Wolfs IM, Keijbeck A, Theodorou K, Wijnands E, Schurgers L, Weber S, Gijbels MJ, Hamers AA, Dreymueller D, Rose-John S, de Winther MP, Ludwig A, Saftig P, Biessen EA, Donners MM.

Am J Pathol. 2015 Apr;185(4):1145-55. doi: 10.1016/j.ajpath.2014.11.028. Epub 2015 Feb 7.

PMID:
25659879
14.

6-Mercaptopurine reduces macrophage activation and gut epithelium proliferation through inhibition of GTPase Rac1.

Marinković G, Hamers AA, de Vries CJ, de Waard V.

Inflamm Bowel Dis. 2014 Sep;20(9):1487-95. doi: 10.1097/MIB.0000000000000122.

PMID:
25029617
15.

Limited role of nuclear receptor Nur77 in Escherichia coli-induced peritonitis.

Hamers AA, Uleman S, van Tiel CM, Kruijswijk D, van Stalborch AM, Huveneers S, de Vries CJ, van 't Veer C.

Infect Immun. 2014 Jan;82(1):253-64. doi: 10.1128/IAI.00721-13. Epub 2013 Oct 28.

16.

NR4A nuclear receptors in immunity and atherosclerosis.

Hamers AA, Hanna RN, Nowyhed H, Hedrick CC, de Vries CJ.

Curr Opin Lipidol. 2013 Oct;24(5):381-5. doi: 10.1097/MOL.0b013e3283643eac.

17.

Immunosuppressive drug azathioprine reduces aneurysm progression through inhibition of Rac1 and c-Jun-terminal-N-kinase in endothelial cells.

Marinkovic G, Hibender S, Hoogenboezem M, van Broekhoven A, Girigorie AF, Bleeker N, Hamers AA, Stap J, van Buul JD, de Vries CJ, de Waard V.

Arterioscler Thromb Vasc Biol. 2013 Oct;33(10):2380-8. doi: 10.1161/ATVBAHA.113.301394. Epub 2013 Aug 15.

PMID:
23950142
18.

Nuclear Receptors in atherosclerosis: a superfamily with many 'Goodfellas'.

Kurakula K, Hamers AA, de Waard V, de Vries CJ.

Mol Cell Endocrinol. 2013 Apr 10;368(1-2):71-84. doi: 10.1016/j.mce.2012.05.014. Epub 2012 Jun 2. Review.

PMID:
22664910
19.

Bone marrow-specific deficiency of nuclear receptor Nur77 enhances atherosclerosis.

Hamers AA, Vos M, Rassam F, Marinković G, Kurakula K, van Gorp PJ, de Winther MP, Gijbels MJ, de Waard V, de Vries CJ.

Circ Res. 2012 Feb 3;110(3):428-38. doi: 10.1161/CIRCRESAHA.111.260760. Epub 2011 Dec 22. Erratum in: Circ Res. 2012 Mar 2;110(5):e46. Marincovic, Goran [corrected to Marinković, Goran].

PMID:
22194623
20.

In vitro responses to electrosprayed alkaline phosphatase/calcium phosphate composite coatings.

de Jonge LT, van den Beucken JJ, Leeuwenburgh SC, Hamers AA, Wolke JG, Jansen JA.

Acta Biomater. 2009 Sep;5(7):2773-82. doi: 10.1016/j.actbio.2009.03.019. Epub 2009 Mar 26.

PMID:
19376000
21.

Acro-angiodermatitis of the foot.

Mali JW, Kuiper JP, Hamers AA.

Arch Dermatol. 1965 Nov;92(5):515-8. No abstract available.

PMID:
5844394

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