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Items: 1 to 50 of 174

1.

Pharmacokinetics of tiotropium in asthmatic children aged 6-11 years support its safety profile.

Sharma A, Aalbers R, Hamelmann E, Goldstein S, Engel M, Moroni-Zentgraf P, Vogelberg C.

Pediatr Allergy Immunol. 2018 Jul 4. doi: 10.1111/pai.12952. [Epub ahead of print]

PMID:
29972697
2.

25-Hydroxvitamin D concentrations are not lower in children with bronchial asthma, atopic dermatitis, obesity, or attention-deficient/hyperactivity disorder than in healthy children.

Reinehr T, Langrock C, Hamelmann E, Lücke T, Koerner-Rettberg C, Holtmann M, Legenbauer T, Gest S, Frank M, Schmidt B, Radkowski K, Jöckel KH.

Nutr Res. 2018 Apr;52:39-47. doi: 10.1016/j.nutres.2018.01.002. Epub 2018 Jan 31.

PMID:
29764626
3.

Tiotropium add-on therapy improves lung function in children with symptomatic moderate asthma.

Vogelberg C, Engel M, Laki I, Bernstein JA, Schmidt O, El Azzi G, Moroni-Zentgraf P, Sigmund R, Hamelmann E.

J Allergy Clin Immunol Pract. 2018 May 8. pii: S2213-2198(18)30309-X. doi: 10.1016/j.jaip.2018.04.032. [Epub ahead of print] No abstract available.

4.

Impact of increasing treatment rates on cost-effectiveness of subcutaneous immunotherapy (SCIT) in respiratory allergy: a decision analytic modelling approach.

Richter AK, Klimek L, Merk HF, Mülleneisen N, Renz H, Wehrmann W, Werfel T, Hamelmann E, Siebert U, Sroczynski G, Wasem J, Biermann-Stallwitz J.

Eur J Health Econ. 2018 Mar 24. doi: 10.1007/s10198-018-0970-6. [Epub ahead of print]

PMID:
29574666
5.

Clinical trials in allergen immunotherapy: current concepts and future needs.

Pfaar O, Alvaro M, Cardona V, Hamelmann E, Mösges R, Kleine-Tebbe J.

Allergy. 2018 Feb 15. doi: 10.1111/all.13429. [Epub ahead of print] Review.

PMID:
29446469
6.

Efficacy and Safety of Tiotropium in Children and Adolescents.

Hamelmann E, Szefler SJ.

Drugs. 2018 Mar;78(3):327-338. doi: 10.1007/s40265-018-0862-1. Review.

7.

[Guideline for the Diagnosis and Treatment of Asthma - Guideline of the German Respiratory Society and the German Atemwegsliga in Cooperation with the Paediatric Respiratory Society and the Austrian Society of Pneumology].

Buhl R, Bals R, Baur X, Berdel D, Criée CP, Gappa M, Gillissen A, Greulich T, Haidl P, Hamelmann E, Kardos P, Kenn K, Klimek L, Korn S, Lommatzsch M, Magnussen H, Nicolai T, Nowak D, Pfaar O, Rabe KF, Riedler J, Ritz T, Schultz K, Schuster A, Spindler T, Taube C, Taube K, Vogelmeier C, von Leupold A, Wantke F, Weise S, Wildhaber J, Worth H, Zacharasiewicz A.

Pneumologie. 2017 Dec;71(12):e2. doi: 10.1055/s-0044-100881. Epub 2018 Jan 15. German. No abstract available.

PMID:
29334688
8.

Thyroid Hormone Status in Overweight Children with Attention Deficit/Hyperactivity Disorder.

Langrock C, Hebebrand J, Radowksi K, Hamelmann E, Lücke T, Holtmann M, Legenbauer T, Schmidt B, Frank M, Jöckel KH, Reinehr T.

Horm Res Paediatr. 2018;89(3):150-156. doi: 10.1159/000485620. Epub 2018 Jan 10.

PMID:
29320782
9.

[Guideline for the Diagnosis and Treatment of Asthma - Guideline of the German Respiratory Society and the German Atemwegsliga in Cooperation with the Paediatric Respiratory Society and the Austrian Society of Pneumology].

Deutsche Gesellschaft für Arbeitsmedizin und Umweltmedizin e. V; Deutsche Gesellschaft für Rehabilitationswissenschaften e.V; und Deutsche Gesellschaft für Gynäkologie und Geburtshilfe e.V.;, Buhl R, Bals R, Baur X, Berdel D, Criée CP, Gappa M, Gillissen A, Greulich T, Haidl P, Hamelmann E, Kardos P, Kenn K, Klimek L, Korn S, Lommatzsch M, Magnussen H, Nicolai T, Nowak D, Pfaar O, Rabe KF, Riedler J, Ritz T, Schultz K, Schuster A, Spindler T, Taube C, Taube K, Vogelmeier C, von Leupold A, Wantke F, Weise S, Wildhaber J, Worth H, Zacharasiewicz A.

Pneumologie. 2017 Dec;71(12):849-919. doi: 10.1055/s-0043-119504. Epub 2017 Dec 7. German. Erratum in: Pneumologie. 2017 Dec;71(12 ):e2. Taube, R C [corrected to Taube, C].

10.

Hydrolyzed Formula With Reduced Protein Content Supports Adequate Growth: A Randomized Controlled Noninferiority Trial.

Ahrens B, Hellmuth C, Haiden N, Olbertz D, Hamelmann E, Vusurovic M, Fleddermann M, Roehle R, Knoll A, Koletzko B, Wahn U, Beyer K.

J Pediatr Gastroenterol Nutr. 2018 May;66(5):822-830. doi: 10.1097/MPG.0000000000001853.

PMID:
29216020
11.

Course of respiratory allergy by treatment strategy based on German routine data.

Weschenfelder AK, Klimek L, Mülleneisen N, Renz H, Wehrmann W, Werfel T, Hamelmann E, Wasem J, Biermann J.

Allergo J Int. 2017;26(6):195-203. doi: 10.1007/s40629-017-0027-x. Epub 2017 May 30.

12.

The roadmap for allergology in Europe: The subspecialty of allergology as "stop-over" on the way to a full specialty. An EAACI position statement.

Gerth van Wijk R, Eguiluz-Gracia I, Gayraud J, Gutermuth J, Hamelmann E, Heffler E, Popov TA, Schmid-Grendelmeier P, Tomazic PV, Tsilochristou O, Muelleneisen N.

Allergy. 2018 Mar;73(3):540-548. doi: 10.1111/all.13321. Epub 2017 Oct 26.

PMID:
28960379
13.

EAACI Guidelines on Allergen Immunotherapy: Allergic rhinoconjunctivitis.

Roberts G, Pfaar O, Akdis CA, Ansotegui IJ, Durham SR, Gerth van Wijk R, Halken S, Larenas-Linnemann D, Pawankar R, Pitsios C, Sheikh A, Worm M, Arasi S, Calderon MA, Cingi C, Dhami S, Fauquert JL, Hamelmann E, Hellings P, Jacobsen L, Knol EF, Lin SY, Maggina P, Mösges R, Oude Elberink JNG, Pajno GB, Pastorello EA, Penagos M, Rotiroti G, Schmidt-Weber CB, Timmermans F, Tsilochristou O, Varga EM, Wilkinson JN, Williams A, Zhang L, Agache I, Angier E, Fernandez-Rivas M, Jutel M, Lau S, van Ree R, Ryan D, Sturm GJ, Muraro A.

Allergy. 2018 Apr;73(4):765-798. doi: 10.1111/all.13317. Epub 2017 Oct 30.

PMID:
28940458
14.

Erratum to: Allergen immunotherapy for allergic asthma: protocol for a systematic review.

Dhami S, Nurmatov U, Agache I, Lau S, Muraro A, Jutel M, Roberts G, Akdis C, Bonini M, Calderon M, Casale T, Cavkaytar O, Cox L, Demoly P, Flood B, Hamelmann E, Izuhara K, Kalayci Ö, Kleine-Tebbe J, Nieto A, Papadopoulos N, Pfaar O, Rosenwasser L, Ryan D, Schmidt-Weber C, Szefler S, Wahn U, van Wijk RG, Wilkinson J, Sheikh A.

Clin Transl Allergy. 2017 Sep 15;7:32. doi: 10.1186/s13601-017-0167-6. eCollection 2017.

15.

Erratum to: Allergen immunotherapy for allergic rhinoconjunctivitis: protocol for a systematic review.

Dhami S, Nurmatov U, Roberts G, Pfaar O, Muraro A, Ansotegui IJ, Calderon M, Cingi C, Demoly P, Durham S, van Wijk RG, Halken S, Hamelmann E, Hellings P, Jacobsen L, Knol E, Linnemann DL, Lin S, Maggina V, Oude-Elberink H, Pajno G, Panwankar R, Pastorello E, Pitsios C, Rotiroti G, Timmermans F, Tsilochristou O, Varga EM, Wilkinson J, Williams A, Worm M, Zhang L, Sheikh A.

Clin Transl Allergy. 2017 Sep 15;7:29. doi: 10.1186/s13601-017-0168-5. eCollection 2017.

16.

Allergen immunotherapy for allergic rhinoconjunctivitis: a systematic overview of systematic reviews.

Nurmatov U, Dhami S, Arasi S, Roberts G, Pfaar O, Muraro A, Ansotegui IJ, Calderon M, Cingi C, Durham S, van Wijk RG, Halken S, Hamelmann E, Hellings P, Jacobsen L, Knol E, Larenas-Linnemann D, Lin SY, Maggina V, Oude-Elberink H, Pajno G, Panwankar R, Pastorello E, Pitsios C, Rotiroti G, Timmermans F, Tsilochristou O, Varga EM, Wilkinson J, Williams A, Worm M, Zhang L, Sheikh A.

Clin Transl Allergy. 2017 Aug 8;7:24. doi: 10.1186/s13601-017-0159-6. eCollection 2017. Review.

17.

Allergen immunotherapy for allergic rhinoconjunctivitis: A systematic review and meta-analysis.

Dhami S, Nurmatov U, Arasi S, Khan T, Asaria M, Zaman H, Agarwal A, Netuveli G, Roberts G, Pfaar O, Muraro A, Ansotegui IJ, Calderon M, Cingi C, Durham S, van Wijk RG, Halken S, Hamelmann E, Hellings P, Jacobsen L, Knol E, Larenas-Linnemann D, Lin S, Maggina P, Mösges R, Oude Elberink H, Pajno G, Panwankar R, Pastorello E, Penagos M, Pitsios C, Rotiroti G, Timmermans F, Tsilochristou O, Varga EM, Schmidt-Weber C, Wilkinson J, Williams A, Worm M, Zhang L, Sheikh A.

Allergy. 2017 Nov;72(11):1597-1631. doi: 10.1111/all.13201. Epub 2017 Jul 14. Review.

PMID:
28493631
18.

Reply to 'Can a better patient phenotyping predict the efficacy of tiotropium in asthmatic adolescents?'

Hamelmann E, Vogelberg C, Szefler SJ.

Expert Opin Pharmacother. 2017 Jun;18(8):837-838. doi: 10.1080/14656566.2017.1317984. Epub 2017 Apr 26. No abstract available.

PMID:
28399660
19.

Allergy and school: nothing to be sneezed at!: A primary school project in Bielefeld, Germany, on epidemiology and health promotion in allergic diseases.

Bornemann R, Hagemeister K, Bresser HG, Hamelmann E.

Allergo J Int. 2016;25(7):201-209. doi: 10.1007/s40629-016-0131-3. Epub 2016 Nov 2.

20.

A phase III randomized controlled trial of tiotropium add-on therapy in children with severe symptomatic asthma.

Szefler SJ, Murphy K, Harper T 3rd, Boner A, Laki I, Engel M, El Azzi G, Moroni-Zentgraf P, Finnigan H, Hamelmann E.

J Allergy Clin Immunol. 2017 Nov;140(5):1277-1287. doi: 10.1016/j.jaci.2017.01.014. Epub 2017 Feb 9.

21.

Tiotropium for the treatment of asthma in adolescents.

Hamelmann E, Vogelberg C, Szefler SJ.

Expert Opin Pharmacother. 2017 Feb;18(3):305-312. doi: 10.1080/14656566.2017.1285906. Epub 2017 Feb 1. Review.

PMID:
28110558
22.

[Current Practice of Pre- and Postnatal Screening and Future Developments for Evidence Based Guidelines].

Hebebrand J, Hamelmann E, Hartmann A, Holtmann M, Jöckel KH, Kremer U, Legenbauer T, Lücke T, Radkowski K, Reinehr T, Wand K, Mühlig Y, Föcker M.

Klin Padiatr. 2017 Jan;229(1):2-13. doi: 10.1055/s-0042-118187. Epub 2016 Dec 14. Review. German.

PMID:
27975344
23.

A randomised controlled trial of tiotropium in adolescents with severe symptomatic asthma.

Hamelmann E, Bernstein JA, Vandewalker M, Moroni-Zentgraf P, Verri D, Unseld A, Engel M, Boner AL.

Eur Respir J. 2017 Jan 11;49(1). pii: 1601100. doi: 10.1183/13993003.01100-2016. Print 2017 Jan.

24.

Allergy in severe asthma.

Del Giacco SR, Bakirtas A, Bel E, Custovic A, Diamant Z, Hamelmann E, Heffler E, Kalayci Ö, Saglani S, Sergejeva S, Seys S, Simpson A, Bjermer L.

Allergy. 2017 Feb;72(2):207-220. doi: 10.1111/all.13072. Epub 2016 Nov 23. Review.

25.

Elevated blood eosinophils in early infancy are predictive of atopic dermatitis in children with risk for atopy.

Rossberg S, Gerhold K, Geske T, Zimmermann K, Menke G, Zaino M, Wahn U, Hamelmann E, Lau S.

Pediatr Allergy Immunol. 2016 Nov;27(7):702-708. doi: 10.1111/pai.12607. Epub 2016 Aug 9.

PMID:
27294404
26.
27.

Evidence vs. efficacy in allergen-specific immunotherapy: Considerations using the example of tradable products in Germany.

Brehler R, Klimek L, Vogelberg C, Werfel T, Pfaar O, Hamelmann E.

Allergo J Int. 2016;25:38-43. Epub 2016 Mar 23.

28.

The gut resistome is highly dynamic during the first months of life.

von Wintersdorff CJ, Wolffs PF, Savelkoul PH, Nijsen RR, Lau S, Gerhold K, Hamelmann E, Penders J.

Future Microbiol. 2016;11(4):501-10. doi: 10.2217/fmb.15.154. Epub 2016 Apr 11.

PMID:
27064174
29.

Economic analysis of temperature-controlled laminar airflow (TLA) for the treatment of patients with severe persistent allergic asthma.

Brazier P, Schauer U, Hamelmann E, Holmes S, Pritchard C, Warner JO.

BMJ Open Respir Res. 2016 Mar 23;3(1):e000117. doi: 10.1136/bmjresp-2015-000117. eCollection 2016.

30.

Allergen immunotherapy for allergic rhinoconjunctivitis: protocol for a systematic review.

Dhami S, Nurmatov U, Roberts G, Pfaar O, Muraro A, Ansotegui IJ, Calderon M, Cingi C, Demoly P, Durham S, van Wijk RG, Halken S, Hamelmann E, Hellings P, Jacobsen L, Knol E, Larenas-Linnemann D, Lin S, Maggina V, Oude-Elberink H, Pajno G, Panwankar R, Pastorello E, Pitsios C, Rotiroti G, Timmermans F, Tsilochristou O, Varga EM, Wilkinson J, Williams A, Worm M, Zhang L, Sheikh A.

Clin Transl Allergy. 2016 Mar 22;6:12. doi: 10.1186/s13601-016-0099-6. eCollection 2016. Erratum in: Clin Transl Allergy. 2017 Sep 15;7:29.

31.

Tiotropium add-on therapy in adolescents with moderate asthma: A 1-year randomized controlled trial.

Hamelmann E, Bateman ED, Vogelberg C, Szefler SJ, Vandewalker M, Moroni-Zentgraf P, Avis M, Unseld A, Engel M, Boner AL.

J Allergy Clin Immunol. 2016 Aug;138(2):441-450.e8. doi: 10.1016/j.jaci.2016.01.011. Epub 2016 Mar 5.

32.

Local T/B cooperation in inflamed tissues is supported by T follicular helper-like cells.

Vu Van D, Beier KC, Pietzke LJ, Al Baz MS, Feist RK, Gurka S, Hamelmann E, Kroczek RA, Hutloff A.

Nat Commun. 2016 Feb 26;7:10875. doi: 10.1038/ncomms10875.

33.

Allergen immunotherapy for allergic asthma: protocol for a systematic review.

Dhami S, Nurmatov U, Agache I, Lau S, Muraro A, Jutel M, Roberts G, Akdis C, Bonini M, Calderon M, Casale T, Cavkaytar O, Cox L, Demoly P, Flood B, Hamelmann E, Izuhara K, Kalayci Ö, Kleine-Tebbe J, Nieto A, Papadopoulos N, Pfaar O, Rosenwasser L, Ryan D, Schmidt-Weber C, Szefler S, Wahn U, van Wijk RG, Wilkinson J, Sheikh A.

Clin Transl Allergy. 2016 Feb 9;6:5. doi: 10.1186/s13601-016-0094-y. eCollection 2015. Erratum in: Clin Transl Allergy. 2017 Sep 15;7:32.

34.

Improved asthma control in patients with severe, persistent allergic asthma after 12 months of nightly temperature-controlled laminar airflow: an observational study with retrospective comparisons.

Schauer U, Bergmann KC, Gerstlauer M, Lehmann S, Gappa M, Brenneken A, Schulz C, Ahrens P, Schreiber J, Wittmann M, Hamelmann E; all members of the German Asthma Net (GAN).

Eur Clin Respir J. 2015 Jul 29;2. doi: 10.3402/ecrj.v2.28531. eCollection 2015.

35.

Observational Study on Less Invasive Surfactant Administration (LISA) in Preterm Infants<29 Weeks--Short and Long-term Outcomes.

Teig N, Weitkämper A, Rothermel J, Bigge N, Lilienthal E, Rossler L, Hamelmann E.

Z Geburtshilfe Neonatol. 2015 Dec;219(6):266-73. doi: 10.1055/s-0035-1547295. Epub 2015 Nov 9.

PMID:
26550923
36.

Erratum to: A randomised dose-ranging study of tiotropium Respimat® in children with symptomatic asthma despite inhaled corticosteroids.

Vogelberg C, Moroni-Zentgraf P, Leonaviciute-Klimantaviciene M, Sigmund R, Hamelmann E, Engel M, Szefler S.

Respir Res. 2015 Oct 20;16:128. doi: 10.1186/s12931-015-0290-7. No abstract available.

37.

[Vascular Anomaly in the Midcheek Region of an Infant - Review of the Diagnostic Procedure].

Rossler L, Sander V, Teuber I, Stücker M, Kreuter A, Stricker I, Hamelmann E.

Klin Padiatr. 2015 Jul 16. [Epub ahead of print] German. No abstract available.

PMID:
26181067
38.

[Vascular anomaly in the midcheek region of an infant--review of the diagnostic procedure].

Rossler L, Sander V, Teuber I, Stücker M, Kreuter A, Stricker I, Hamelmann E.

Klin Padiatr. 2015 May;227(3):176-80. doi: 10.1055/s-0035-1548945. Epub 2015 May 18. German.

PMID:
25985453
39.

A randomised dose-ranging study of tiotropium Respimat® in children with symptomatic asthma despite inhaled corticosteroids.

Vogelberg C, Moroni-Zentgraf P, Leonaviciute-Klimantaviciene M, Sigmund R, Hamelmann E, Engel M, Szefler S.

Respir Res. 2015 Feb 7;16:20. doi: 10.1186/s12931-015-0175-9. Erratum in: Respir Res. 2015;16:128.

40.

Pimecrolimus in atopic dermatitis: consensus on safety and the need to allow use in infants.

Luger T, Boguniewicz M, Carr W, Cork M, Deleuran M, Eichenfield L, Eigenmann P, Fölster-Holst R, Gelmetti C, Gollnick H, Hamelmann E, Hebert AA, Muraro A, Oranje AP, Paller AS, Paul C, Puig L, Ring J, Siegfried E, Spergel JM, Stingl G, Taieb A, Torrelo A, Werfel T, Wahn U.

Pediatr Allergy Immunol. 2015 Jun;26(4):306-15. doi: 10.1111/pai.12331. Epub 2015 Apr 13. Review.

41.

Therapeutic potential of larval excretory/secretory proteins of the pig whipworm Trichuris suis in allergic disease.

Ebner F, Hepworth MR, Rausch S, Janek K, Niewienda A, Kühl A, Henklein P, Lucius R, Hamelmann E, Hartmann S.

Allergy. 2014 Nov;69(11):1489-97. doi: 10.1111/all.12496. Epub 2014 Sep 6.

PMID:
25069662
42.

Development of an animal model to evaluate the allergenicity of food allergens.

Ahrens B, Quarcoo D, Buhner S, Reese G, Vieths S, Hamelmann E.

Int Arch Allergy Immunol. 2014;164(2):89-96. doi: 10.1159/000363109. Epub 2014 Jun 4.

PMID:
24903216
43.

Modified oral food challenge used with sensitization biomarkers provides more real-life clinical thresholds for peanut allergy.

Blumchen K, Beder A, Beschorner J, Ahrens F, Gruebl A, Hamelmann E, Hansen G, Heinzmann A, Nemat K, Niggemann B, Wahn U, Beyer K.

J Allergy Clin Immunol. 2014 Aug;134(2):390-8. doi: 10.1016/j.jaci.2014.03.035. Epub 2014 May 13.

PMID:
24831438
44.

New insights into the hygiene hypothesis in allergic diseases: mediation of sibling and birth mode effects by the gut microbiota.

Penders J, Gerhold K, Thijs C, Zimmermann K, Wahn U, Lau S, Hamelmann E.

Gut Microbes. 2014 Mar-Apr;5(2):239-44. doi: 10.4161/gmic.27905. Epub 2014 Jan 23.

45.

Efficacy and safety of the probiotic Lactobacillus paracasei LP-33 in allergic rhinitis: a double-blind, randomized, placebo-controlled trial (GA2LEN Study).

Costa DJ, Marteau P, Amouyal M, Poulsen LK, Hamelmann E, Cazaubiel M, Housez B, Leuillet S, Stavnsbjerg M, Molimard P, Courau S, Bousquet J.

Eur J Clin Nutr. 2014 May;68(5):602-7. doi: 10.1038/ejcn.2014.13. Epub 2014 Feb 26.

PMID:
24569538
46.

EAACI position statement on asthma exacerbations and severe asthma.

Custovic A, Johnston SL, Pavord I, Gaga M, Fabbri L, Bel EH, Le Souëf P, Lötvall J, Demoly P, Akdis CA, Ryan D, Mäkelä MJ, Martinez F, Holloway JW, Saglani S, O'Byrne P, Papi A, Sergejeva S, Magnan A, Del Giacco S, Kalayci O, Hamelmann E, Papadopoulos NG.

Allergy. 2013 Dec;68(12):1520-31. doi: 10.1111/all.12275. Epub 2013 Nov 6. Review.

PMID:
24410781
48.

S3-Guideline on allergy prevention: 2014 update: Guideline of the German Society for Allergology and Clinical Immunology (DGAKI) and the German Society for Pediatric and Adolescent Medicine (DGKJ).

Schäfer T, Bauer CP, Beyer K, Bufe A, Friedrichs F, Gieler U, Gronke G, Hamelmann E, Hellermann M, Kleinheinz A, Klimek L, Koletzko S, Kopp M, Lau S, Müsken H, Reese I, Schmidt S, Schnadt S, Sitter H, Strömer K, Vagts J, Vogelberg C, Wahn U, Werfel T, Worm M, Muche-Borowski C.

Allergo J Int. 2014;23(6):186-199.

49.

Nucleotide oligomerization domain 1 ligation suppressed murine allergen-specific T-cell proliferation and airway hyperresponsiveness.

Tabeling C, Scheer H, Schönrock SM, Runge F, Gutbier B, Lienau J, Hamelmann E, Opitz B, Suttorp N, Mayer K, Behrens GM, Tschernig T, Witzenrath M.

Am J Respir Cell Mol Biol. 2014 May;50(5):903-11. doi: 10.1165/rcmb.2013-0333OC.

PMID:
24279792
50.

Establishment of the intestinal microbiota and its role for atopic dermatitis in early childhood.

Penders J, Gerhold K, Stobberingh EE, Thijs C, Zimmermann K, Lau S, Hamelmann E.

J Allergy Clin Immunol. 2013 Sep;132(3):601-607.e8. doi: 10.1016/j.jaci.2013.05.043. Epub 2013 Jul 27.

PMID:
23900058

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