Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 54

1.

The protein-specific activities of the transmembrane modules of Ptch1 and Ptch2 are determined by their adjacent protein domains.

Fleet AJ, Hamel PA.

J Biol Chem. 2018 Oct 26;293(43):16583-16595. doi: 10.1074/jbc.RA118.004478. Epub 2018 Aug 30.

PMID:
30166346
2.

Activities of the Cytoplasmic Domains of Patched-1 Modulate but Are Not Essential for the Regulation of Canonical Hedgehog Signaling.

Fleet A, Lee JP, Tamachi A, Javeed I, Hamel PA.

J Biol Chem. 2016 Aug 19;291(34):17557-68. doi: 10.1074/jbc.M116.731745. Epub 2016 Jun 20.

3.

Oestrogen receptor-alpha regulates non-canonical Hedgehog-signalling in the mammary gland.

Okolowsky N, Furth PA, Hamel PA.

Dev Biol. 2014 Jul 15;391(2):219-29. doi: 10.1016/j.ydbio.2014.04.007. Epub 2014 Apr 21.

4.

Distinct effects of the mesenchymal dysplasia gene variant of murine Patched-1 protein on canonical and non-canonical Hedgehog signaling pathways.

Harvey MC, Fleet A, Okolowsky N, Hamel PA.

J Biol Chem. 2014 Apr 11;289(15):10939-49. doi: 10.1074/jbc.M113.514844. Epub 2014 Feb 25.

5.

Wnt-signalling in the embryonic mammary gland.

Boras-Granic K, Hamel PA.

J Mammary Gland Biol Neoplasia. 2013 Jun;18(2):155-63. doi: 10.1007/s10911-013-9280-x. Epub 2013 May 10. Review.

PMID:
23660702
6.

Mammary epithelial-restricted expression of activated c-src rescues the block to mammary gland morphogenesis due to the deletion of the C-terminus of Patched-1.

Chang H, Balenci L, Okolowsky N, Muller WJ, Hamel PA.

Dev Biol. 2012 Oct 15;370(2):187-97. doi: 10.1016/j.ydbio.2012.07.027. Epub 2012 Aug 9.

7.

Activation of Erk by sonic hedgehog independent of canonical hedgehog signalling.

Chang H, Li Q, Moraes RC, Lewis MT, Hamel PA.

Int J Biochem Cell Biol. 2010 Sep;42(9):1462-71. doi: 10.1016/j.biocel.2010.04.016. Epub 2010 May 6.

8.

Lymphoid enhancer factor-1 mediates loading of Pax3 to a promoter harbouring lymphoid enhancer factor-1 binding sites resulting in enhancement of transcription.

Christova T, Mojtahedi G, Hamel PA.

Int J Biochem Cell Biol. 2010 May;42(5):630-40. doi: 10.1016/j.biocel.2009.12.006. Epub 2009 Dec 16.

PMID:
20006729
9.

Loss of ALX4 expression in epithelial cells and adjacent stromal cells in breast cancer.

Chang H, Mohabir N, Done S, Hamel PA.

J Clin Pathol. 2009 Oct;62(10):908-14. doi: 10.1136/jcp.2009.067298.

PMID:
19783719
10.

Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation.

Moraes RC, Chang H, Harrington N, Landua JD, Prigge JT, Lane TF, Wainwright BJ, Hamel PA, Lewis MT.

Development. 2009 May;136(9):1423-32. doi: 10.1242/dev.023994. Epub 2009 Mar 18.

11.

Loss of Alx4, a stromally-restricted homeodomain protein, impairs mammary epithelial morphogenesis.

Joshi PA, Chang H, Hamel PA.

Dev Biol. 2006 Sep 1;297(1):284-94. Epub 2006 Jun 2.

12.

Genetic interaction between Lef1 and Alx4 is required for early embryonic development.

Boras-Granic K, Grosschedl R, Hamel PA.

Int J Dev Biol. 2006;50(7):601-10.

13.

Lef1 is required for the transition of Wnt signaling from mesenchymal to epithelial cells in the mouse embryonic mammary gland.

Boras-Granic K, Chang H, Grosschedl R, Hamel PA.

Dev Biol. 2006 Jul 1;295(1):219-31. Epub 2006 Apr 3.

14.

Cell-type-specific regulation of distinct sets of gene targets by Pax3 and Pax3/FKHR.

Begum S, Emami N, Cheung A, Wilkins O, Der S, Hamel PA.

Oncogene. 2005 Mar 10;24(11):1860-72. Erratum in: Oncogene. 2008 Mar 13;27(12):1812. Emani, Nashmil [corrected to Emami, Nashmil].

PMID:
15688035
15.

Homeless people's trust and interactions with police and paramedics.

Zakrison TL, Hamel PA, Hwang SW.

J Urban Health. 2004 Dec;81(4):596-605.

16.

The prevalence of psychological morbidity in West Bank Palestinian children.

Zakrison TL, Shahen A, Mortaja S, Hamel PA.

Can J Psychiatry. 2004 Jan;49(1):60-3.

PMID:
14763680
17.

Shh expression is required for embryonic hair follicle but not mammary gland development.

Michno K, Boras-Granic K, Mill P, Hui CC, Hamel PA.

Dev Biol. 2003 Dec 1;264(1):153-65.

19.

Pax3 induces cell aggregation and regulates phenotypic mesenchymal-epithelial interconversion.

Wiggan O, Fadel MP, Hamel PA.

J Cell Sci. 2002 Feb 1;115(Pt 3):517-29.

20.

Alx4 binding to LEF-1 regulates N-CAM promoter activity.

Boras K, Hamel PA.

J Biol Chem. 2002 Jan 11;277(2):1120-7. Epub 2001 Nov 5.

21.

Integration of the pRB and p53 cell cycle control pathways.

Stewart CL, Soria AM, Hamel PA.

J Neurooncol. 2001 Feb;51(3):183-204. Review.

PMID:
11407592
22.

Alterations of the p53 and pRB pathways in human astrocytoma.

Rutka JT, Akiyama Y, Lee SP, Ivanchuk S, Tsugu A, Hamel PA.

Brain Tumor Pathol. 2000;17(2):65-70. Review.

PMID:
11210173
23.

Expression of p57(KIP2) potently blocks the growth of human astrocytomas and induces cell senescence.

Tsugu A, Sakai K, Dirks PB, Jung S, Weksberg R, Fei YL, Mondal S, Ivanchuk S, Ackerley C, Hamel PA, Rutka JT.

Am J Pathol. 2000 Sep;157(3):919-32.

25.

Alx-4, a transcriptional activator whose expression is restricted to sites of epithelial-mesenchymal interactions.

Hudson R, Taniguchi-Sidle A, Boras K, Wiggan O, Hamel PA.

Dev Dyn. 1998 Oct;213(2):159-69.

26.

The E2F-family proteins induce distinct cell cycle regulatory factors in p16-arrested, U343 astrocytoma cells.

Dirks PB, Rutka JT, Hubbard SL, Mondal S, Hamel PA.

Oncogene. 1998 Aug 20;17(7):867-76.

27.
28.

Interaction of the pRB-family proteins with factors containing paired-like homeodomains.

Wiggan O, Taniguchi-Sidle A, Hamel PA.

Oncogene. 1998 Jan 15;16(2):227-36.

29.

Retinoic acid and the cyclin dependent kinase inhibitors synergistically alter proliferation and morphology of U343 astrocytoma cells.

Dirks PB, Patel K, Hubbard SL, Ackerley C, Hamel PA, Rutka JT.

Oncogene. 1997 Oct 23;15(17):2037-48.

30.

G1 cyclins and control of the cell division cycle in normal and transformed cells.

Hamel PA, Hanley-Hyde J.

Cancer Invest. 1997;15(2):143-52. Review.

PMID:
9095210
31.

Activity of the retinoblastoma family proteins, pRB, p107, and p130, during cellular proliferation and differentiation.

Sidle A, Palaty C, Dirks P, Wiggan O, Kiess M, Gill RM, Wong AK, Hamel PA.

Crit Rev Biochem Mol Biol. 1996 Jun;31(3):237-71. Review.

PMID:
8817077
32.

Molecular cloning, chromosomal mapping, and expression of the mouse p107 gene.

Huppi K, Siwarski D, Mock BA, Dosik J, Hamel PA.

Mamm Genome. 1996 May;7(5):353-5.

PMID:
8661722
33.

Regulation of calcium binding proteins calreticulin and calsequestrin during differentiation in the myogenic cell line L6.

Tharin S, Hamel PA, Conway EM, Michalak M, Opas M.

J Cell Physiol. 1996 Mar;166(3):547-60.

PMID:
8600158
34.
35.

Direct transcriptional repression by pRB and its reversal by specific cyclins.

Bremner R, Cohen BL, Sopta M, Hamel PA, Ingles CJ, Gallie BL, Phillips RA.

Mol Cell Biol. 1995 Jun;15(6):3256-65.

37.

Characterization of the human RB1 promoter and of elements involved in transcriptional regulation.

Gill RM, Hamel PA, Zhe J, Zacksenhaus E, Gallie BL, Phillips RA.

Cell Growth Differ. 1994 May;5(5):467-74.

38.

Speculations on the roles of RB1 in tissue-specific differentiation, tumor initiation, and tumor progression.

Hamel PA, Phillips RA, Muncaster M, Gallie BL.

FASEB J. 1993 Jul;7(10):846-54. Review.

PMID:
8344484
39.

Regulated expression of the retinoblastoma gene in differentiating embryonal carcinoma cells.

Slack RS, Hamel PA, Bladon TS, Gill RM, McBurney MW.

Oncogene. 1993 Jun;8(6):1585-91.

PMID:
8502481
40.
41.

The retinoblastoma protein and the cell cycle.

Sopta M, Gallie BL, Gill RM, Hamel PA, Muncaster M, Zacksenhaus E, Phillips RA.

Semin Cancer Biol. 1992 Jun;3(3):107-13. Review.

PMID:
1511153
42.

The retinoblastoma protein and cell cycle regulation.

Hamel PA, Gallie BL, Phillips RA.

Trends Genet. 1992 May;8(5):180-5. Review.

PMID:
1369744
44.

How do retinoblastoma tumours form?

Gallie BL, Dunn JM, Hamel PA, Muncaster M, Cohen BL, Phillips RA.

Eye (Lond). 1992;6 ( Pt 2):226-31. Review.

PMID:
1624050
45.

Why don't germline mutations in RB1 predispose to leukemia?

Phillips RA, Gill RM, Zacksenhaus E, Bremner R, Jiang Z, Sopta M, Gallie BL, Hamel PA.

Curr Top Microbiol Immunol. 1992;182:485-91. Review. No abstract available.

PMID:
1490389
46.

The genetics of retinoblastoma. Relevance to the patient.

Gallie BL, Dunn JM, Chan HS, Hamel PA, Phillips RA.

Pediatr Clin North Am. 1991 Apr;38(2):299-315. Review.

PMID:
2006079
47.
48.

Point mutations in retinoblastoma.

Gallie BL, Dunn JM, Hamel PA, Phillips RA.

N Engl J Med. 1990 May 10;322(19):1397-8. No abstract available.

PMID:
2325742
49.

Contributions of immunoglobulin heavy and light chains to antibody specificity for lysozyme and two haptens.

Smith-Gill SJ, Hamel PA, Lovoie TB, Dorrington KJ.

J Immunol. 1987 Dec 15;139(12):4135-44.

PMID:
2447160
50.

Supplemental Content

Loading ...
Support Center