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Items: 1 to 50 of 65

1.

Tau deletion promotes brain insulin resistance.

Marciniak E, Leboucher A, Caron E, Ahmed T, Tailleux A, Dumont J, Issad T, Gerhardt E, Pagesy P, Vileno M, Bournonville C, Hamdane M, Bantubungi K, Lancel S, Demeyer D, Eddarkaoui S, Vallez E, Vieau D, Humez S, Faivre E, Grenier-Boley B, Outeiro TF, Staels B, Amouyel P, Balschun D, Buee L, Blum D.

J Exp Med. 2017 Aug 7;214(8):2257-2269. doi: 10.1084/jem.20161731. Epub 2017 Jun 26.

2.

The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function.

Batalha VL, Ferreira DG, Coelho JE, Valadas JS, Gomes R, Temido-Ferreira M, Shmidt T, Baqi Y, Buée L, Müller CE, Hamdane M, Outeiro TF, Bader M, Meijsing SH, Sadri-Vakili G, Blum D, Lopes LV.

Sci Rep. 2016 Aug 11;6:31493. doi: 10.1038/srep31493.

3.

A2A adenosine receptor deletion is protective in a mouse model of Tauopathy.

Laurent C, Burnouf S, Ferry B, Batalha VL, Coelho JE, Baqi Y, Malik E, Marciniak E, Parrot S, Van der Jeugd A, Faivre E, Flaten V, Ledent C, D'Hooge R, Sergeant N, Hamdane M, Humez S, Müller CE, Lopes LV, Buée L, Blum D.

Mol Psychiatry. 2016 Jan;21(1):149. doi: 10.1038/mp.2015.115. Epub 2015 Jul 28. No abstract available.

PMID:
26216297
4.

Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated forms.

Derisbourg M, Leghay C, Chiappetta G, Fernandez-Gomez FJ, Laurent C, Demeyer D, Carrier S, Buée-Scherrer V, Blum D, Vinh J, Sergeant N, Verdier Y, Buée L, Hamdane M.

Sci Rep. 2015 May 14;5:9659. doi: 10.1038/srep09659.

5.

The FK506-binding protein FKBP52 in vitro induces aggregation of truncated Tau forms with prion-like behavior.

Giustiniani J, Guillemeau K, Dounane O, Sardin E, Huvent I, Schmitt A, Hamdane M, Buée L, Landrieu I, Lippens G, Baulieu EE, Chambraud B.

FASEB J. 2015 Aug;29(8):3171-81. doi: 10.1096/fj.14-268243. Epub 2015 Apr 17.

PMID:
25888602
6.

Chloroquine and chloroquinoline derivatives as models for the design of modulators of amyloid Peptide precursor metabolism.

Melnyk P, Vingtdeux V, Burlet S, Eddarkaoui S, Grosjean ME, Larchanché PE, Hochart G, Sergheraert C, Estrella C, Barrier M, Poix V, Plancq P, Lannoo C, Hamdane M, Delacourte A, Verwaerde P, Buée L, Sergeant N.

ACS Chem Neurosci. 2015 Apr 15;6(4):559-69. doi: 10.1021/cn5003013. Epub 2015 Feb 6.

PMID:
25611616
7.

A2A adenosine receptor deletion is protective in a mouse model of Tauopathy.

Laurent C, Burnouf S, Ferry B, Batalha VL, Coelho JE, Baqi Y, Malik E, Mariciniak E, Parrot S, Van der Jeugd A, Faivre E, Flaten V, Ledent C, D'Hooge R, Sergeant N, Hamdane M, Humez S, Müller CE, Lopes LV, Buée L, Blum D.

Mol Psychiatry. 2016 Jan;21(1):97-107. doi: 10.1038/mp.2014.151. Epub 2014 Dec 2. Erratum in: Mol Psychiatry. 2016 Jan;21(1):149. Mariciniak, E [Corrected to Marciniak, E].

PMID:
25450226
8.

Beneficial effects of caffeine in a transgenic model of Alzheimer's disease-like tau pathology.

Laurent C, Eddarkaoui S, Derisbourg M, Leboucher A, Demeyer D, Carrier S, Schneider M, Hamdane M, Müller CE, Buée L, Blum D.

Neurobiol Aging. 2014 Sep;35(9):2079-90. doi: 10.1016/j.neurobiolaging.2014.03.027. Epub 2014 Mar 29.

PMID:
24780254
9.

Consensus brain-derived protein, extraction protocol for the study of human and murine brain proteome using both 2D-DIGE and mini 2DE immunoblotting.

Fernandez-Gomez FJ, Jumeau F, Derisbourg M, Burnouf S, Tran H, Eddarkaoui S, Obriot H, Dutoit-Lefevre V, Deramecourt V, Mitchell V, Lefranc D, Hamdane M, Blum D, Buée L, Buée-Scherrer V, Sergeant N.

J Vis Exp. 2014 Apr 10;(86). doi: 10.3791/51339.

10.

Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-β hydrolysis.

Charton J, Gauriot M, Guo Q, Hennuyer N, Marechal X, Dumont J, Hamdane M, Pottiez V, Landry V, Sperandio O, Flipo M, Buee L, Staels B, Leroux F, Tang WJ, Deprez B, Deprez-Poulain R.

Eur J Med Chem. 2014 May 22;79:184-93. doi: 10.1016/j.ejmech.2014.04.009. Epub 2014 Apr 4.

11.

From epidemiology to pathophysiology: what about caffeine in Alzheimer's disease?

Flaten V, Laurent C, Coelho JE, Sandau U, Batalha VL, Burnouf S, Hamdane M, Humez S, Boison D, Lopes LV, Buée L, Blum D.

Biochem Soc Trans. 2014 Apr;42(2):587-92. doi: 10.1042/BST20130229. Review.

12.

MUC1-C nuclear localization drives invasiveness of renal cancer cells through a sheddase/gamma secretase dependent pathway.

Bouillez A, Gnemmi V, Gaudelot K, Hémon B, Ringot B, Pottier N, Glowacki F, Butruille C, Cauffiez C, Hamdane M, Sergeant N, Van Seuningen I, Leroy X, Aubert S, Perrais M.

Oncotarget. 2014 Feb 15;5(3):754-63.

13.

Progressive age-related cognitive decline in tau mice.

Van der Jeugd A, Vermaercke B, Derisbourg M, Lo AC, Hamdane M, Blum D, Buée L, D'Hooge R.

J Alzheimers Dis. 2013;37(4):777-88. doi: 10.3233/JAD-130110.

PMID:
23948912
14.

Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology.

Chapuis J, Hansmannel F, Gistelinck M, Mounier A, Van Cauwenberghe C, Kolen KV, Geller F, Sottejeau Y, Harold D, Dourlen P, Grenier-Boley B, Kamatani Y, Delepine B, Demiautte F, Zelenika D, Zommer N, Hamdane M, Bellenguez C, Dartigues JF, Hauw JJ, Letronne F, Ayral AM, Sleegers K, Schellens A, Broeck LV, Engelborghs S, De Deyn PP, Vandenberghe R, O'Donovan M, Owen M, Epelbaum J, Mercken M, Karran E, Bantscheff M, Drewes G, Joberty G, Campion D, Octave JN, Berr C, Lathrop M, Callaerts P, Mann D, Williams J, Buée L, Dewachter I, Van Broeckhoven C, Amouyel P, Moechars D, Dermaut B, Lambert JC; GERAD consortium.

Mol Psychiatry. 2013 Nov;18(11):1225-34. doi: 10.1038/mp.2013.1. Epub 2013 Feb 12.

15.

Giant gastric lipoma mimicking well-differentiated liposarcoma.

Hamdane MM, Brahim EB, Salah MB, Haouas N, Bouhafa A, Chedly-Debbiche A.

Pan Afr Med J. 2012;13:16. Epub 2012 Sep 23.

16.

Detrimental effects of diet-induced obesity on τ pathology are independent of insulin resistance in τ transgenic mice.

Leboucher A, Laurent C, Fernandez-Gomez FJ, Burnouf S, Troquier L, Eddarkaoui S, Demeyer D, Caillierez R, Zommer N, Vallez E, Bantubungi K, Breton C, Pigny P, Buée-Scherrer V, Staels B, Hamdane M, Tailleux A, Buée L, Blum D.

Diabetes. 2013 May;62(5):1681-8. doi: 10.2337/db12-0866. Epub 2012 Dec 18.

17.

Ewing-like adamantinoma.

Hamdane MM, Charfi L, Driss M, Nouri H, Sellami-Dhouib R, Mrad K, Mestiri M, Ben Romdhane K.

Orthop Traumatol Surg Res. 2012 Nov;98(7):845-9. doi: 10.1016/j.otsr.2012.06.015. Epub 2012 Oct 16.

18.

NMDA receptor dysfunction contributes to impaired brain-derived neurotrophic factor-induced facilitation of hippocampal synaptic transmission in a Tau transgenic model.

Burnouf S, Martire A, Derisbourg M, Laurent C, Belarbi K, Leboucher A, Fernandez-Gomez FJ, Troquier L, Eddarkaoui S, Grosjean ME, Demeyer D, Muhr-Tailleux A, Buisson A, Sergeant N, Hamdane M, Humez S, Popoli P, Buée L, Blum D.

Aging Cell. 2013 Feb;12(1):11-23. doi: 10.1111/acel.12018. Epub 2012 Nov 23.

19.

[Malignant melanoma of the nasal cavity].

Rekik W, Goucha A, Hamdane MM, Debbabi B, El May A, Gammoudi A.

Pan Afr Med J. 2012;12:68. Epub 2012 Jul 11. French. No abstract available.

20.

Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker.

Ando K, Dourlen P, Sambo AV, Bretteville A, Bélarbi K, Vingtdeux V, Eddarkaoui S, Drobecq H, Ghestem A, Bégard S, Demey-Thomas E, Melnyk P, Smet C, Lippens G, Maurage CA, Caillet-Boudin ML, Verdier Y, Vinh J, Landrieu I, Galas MC, Blum D, Hamdane M, Sergeant N, Buée L.

Neurobiol Aging. 2013 Mar;34(3):757-69. doi: 10.1016/j.neurobiolaging.2012.08.004. Epub 2012 Aug 25.

PMID:
22926167
21.

[Synchronous rectal adenocarcinoma and duodenal stromal tumor].

Hamdane MM, Bel Haj Salah M, Khayat O, Dhaoui A, Ben Salem A, Koubaa W, Labbene MN, Houas N, Cherif A, Ben Brahim E, Chedly-Debbiche A.

Tunis Med. 2012 May;90(5):416-7. French. No abstract available.

22.

[Gastric adenocarcinoma producing alpha-fetoprotein].

Bouaita L, Sassi S, Hamdane MM, Boussen H, Ben Romdhane K, Mezlini A.

Tunis Med. 2012 Feb;90(2):189-91. French. No abstract available.

23.

[A rare uterine tumor in a 17 year-old girl].

Sassi S, Hamdane MM, Sellami Dhouib R, Doghri R, Mrad K, Kacem D, Ben Romdhane K.

Tunis Med. 2012 Jan;90(1):88-90. French. No abstract available.

24.

Hippocampal BDNF expression in a tau transgenic mouse model.

Burnouf S, Belarbi K, Troquier L, Derisbourg M, Demeyer D, Leboucher A, Laurent C, Hamdane M, Buee L, Blum D.

Curr Alzheimer Res. 2012 May;9(4):406-10.

PMID:
22272617
25.

A rare case of ovarian juvenile granulosa cell tumor without precocious pseudopuberty in an 11-month-old infant.

Hamdane MM, Dhouib R, Charfi L, Doghri R, Mrad K, Ben Romdhane K.

J Pediatr Surg. 2012 Jan;47(1):269-70. doi: 10.1016/j.jpedsurg.2011.10.061. No abstract available.

PMID:
22244428
26.

Giant gastric lipoma mimicking well-differentiated liposarcoma.

Hamdane MM, Brahim EB, Salah MB, Haouas N, Bouhafa A, Chedly-Debbiche A.

Gastroenterol Hepatol Bed Bench. 2012 Winter;5(1):60-3.

27.

[Primary colonic clear cell adenocarcinoma].

Hannachi Sassi S, Hamdane MM, Driss M, Mrad K, Abbes I, Ben Hmida N, Kacem D, Ben Romdhane K.

Tunis Med. 2011 Oct;89(10):803-4. French. No abstract available.

28.

Loss of medial septum cholinergic neurons in THY-Tau22 mouse model: what links with tau pathology?

Belarbi K, Burnouf S, Fernandez-Gomez FJ, Desmercières J, Troquier L, Brouillette J, Tsambou L, Grosjean ME, Caillierez R, Demeyer D, Hamdane M, Schindowski K, Blum D, Buée L.

Curr Alzheimer Res. 2011 Sep;8(6):633-8.

PMID:
21605043
29.

Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology.

Belarbi K, Burnouf S, Fernandez-Gomez FJ, Laurent C, Lestavel S, Figeac M, Sultan A, Troquier L, Leboucher A, Caillierez R, Grosjean ME, Demeyer D, Obriot H, Brion I, Barbot B, Galas MC, Staels B, Humez S, Sergeant N, Schraen-Maschke S, Muhr-Tailleux A, Hamdane M, Buée L, Blum D.

Neurobiol Dis. 2011 Aug;43(2):486-94. doi: 10.1016/j.nbd.2011.04.022. Epub 2011 May 4.

PMID:
21569847
30.

[The hydatid cyst of the spermatic cord: an exceptional localization].

Hamdane MM, Bougrine F, Msakni I, Dhaoui-Ghozzi A, Bouziani A.

Pan Afr Med J. 2011;10:58. Epub 2011 Dec 18. French. No abstract available.

31.

[Molecular actors in Alzheimer's disease: which diagnostic and therapeutic consequences?].

Buée L, Blum D, Bombois S, Buée-Scherrer V, Caillet-Boudin ML, Colin M, Deramecourt V, Dhaenens CM, Galas MC, Hamdane M, Humez S, Maurage CA, Pasquier F, Sablonnière B, Schraen-Maschke S, Sergeant N.

Therapie. 2010 Sep-Oct;65(5):401-7. doi: 10.2515/therapie/2010054. Epub 2010 Dec 13. French.

PMID:
21144474
32.

NMR spectroscopy of the neuronal tau protein: normal function and implication in Alzheimer's disease.

Landrieu I, Leroy A, Smet-Nocca C, Huvent I, Amniai L, Hamdane M, Sibille N, Buée L, Wieruszeski JM, Lippens G.

Biochem Soc Trans. 2010 Aug;38(4):1006-11. doi: 10.1042/BST0381006. Review.

PMID:
20658994
33.

From tau phosphorylation to tau aggregation: what about neuronal death?

Buée L, Troquier L, Burnouf S, Belarbi K, Van der Jeugd A, Ahmed T, Fernandez-Gomez F, Caillierez R, Grosjean ME, Begard S, Barbot B, Demeyer D, Obriot H, Brion I, Buée-Scherrer V, Maurage CA, Balschun D, D'hooge R, Hamdane M, Blum D, Sergeant N.

Biochem Soc Trans. 2010 Aug;38(4):967-72. doi: 10.1042/BST0380967. Review.

PMID:
20658986
34.

Early Tau pathology involving the septo-hippocampal pathway in a Tau transgenic model: relevance to Alzheimer's disease.

Belarbi K, Schindowski K, Burnouf S, Caillierez R, Grosjean ME, Demeyer D, Hamdane M, Sergeant N, Blum D, Buée L.

Curr Alzheimer Res. 2009 Apr;6(2):152-7.

35.

Two-dimensional electrophoresis of tau mutants reveals specific phosphorylation pattern likely linked to early tau conformational changes.

Bretteville A, Ando K, Ghestem A, Loyens A, Bégard S, Beauvillain JC, Sergeant N, Hamdane M, Buée L.

PLoS One. 2009;4(3):e4843. doi: 10.1371/journal.pone.0004843. Epub 2009 Mar 17.

36.

PUFA induce antidepressant-like effects in parallel to structural and molecular changes in the hippocampus.

Venna VR, Deplanque D, Allet C, Belarbi K, Hamdane M, Bordet R.

Psychoneuroendocrinology. 2009 Feb;34(2):199-211. doi: 10.1016/j.psyneuen.2008.08.025. Epub 2008 Oct 10.

PMID:
18848400
37.

Biochemistry of Tau in Alzheimer's disease and related neurological disorders.

Sergeant N, Bretteville A, Hamdane M, Caillet-Boudin ML, Grognet P, Bombois S, Blum D, Delacourte A, Pasquier F, Vanmechelen E, Schraen-Maschke S, Buée L.

Expert Rev Proteomics. 2008 Apr;5(2):207-24. doi: 10.1586/14789450.5.2.207. Review.

PMID:
18466052
38.

The peptidyl prolyl cis/trans isomerase Pin1 downregulates the Inhibitor of Apoptosis Protein Survivin.

Dourlen P, Ando K, Hamdane M, Begard S, Buée L, Galas MC.

Biochim Biophys Acta. 2007 Sep;1773(9):1428-37. Epub 2007 Jun 2.

39.
40.

Alkalizing drugs induce accumulation of amyloid precursor protein by-products in luminal vesicles of multivesicular bodies.

Vingtdeux V, Hamdane M, Loyens A, Gelé P, Drobeck H, Bégard S, Galas MC, Delacourte A, Beauvillain JC, Buée L, Sergeant N.

J Biol Chem. 2007 Jun 22;282(25):18197-205. Epub 2007 Apr 27.

41.

Intracellular pH regulates amyloid precursor protein intracellular domain accumulation.

Vingtdeux V, Hamdane M, Bégard S, Loyens A, Delacourte A, Beauvillain JC, Buée L, Marambaud P, Sergeant N.

Neurobiol Dis. 2007 Mar;25(3):686-96. Epub 2007 Jan 3.

PMID:
17207630
42.
43.

Pin1 allows for differential Tau dephosphorylation in neuronal cells.

Hamdane M, Dourlen P, Bretteville A, Sambo AV, Ferreira S, Ando K, Kerdraon O, Bégard S, Geay L, Lippens G, Sergeant N, Delacourte A, Maurage CA, Galas MC, Buée L.

Mol Cell Neurosci. 2006 May-Jun;32(1-2):155-60. Epub 2006 May 11.

PMID:
16697218
44.

The peptidylprolyl cis/trans-isomerase Pin1 modulates stress-induced dephosphorylation of Tau in neurons. Implication in a pathological mechanism related to Alzheimer disease.

Galas MC, Dourlen P, Bégard S, Ando K, Blum D, Hamdane M, Buée L.

J Biol Chem. 2006 Jul 14;281(28):19296-304. Epub 2006 May 3.

45.

Phosphorylation of amyloid precursor carboxy-terminal fragments enhances their processing by a gamma-secretase-dependent mechanism.

Vingtdeux V, Hamdane M, Gompel M, Bégard S, Drobecq H, Ghestem A, Grosjean ME, Kostanjevecki V, Grognet P, Vanmechelen E, Buée L, Delacourte A, Sergeant N.

Neurobiol Dis. 2005 Nov;20(2):625-37. Epub 2005 Jun 3.

PMID:
15936948
46.

p25/Cdk5-mediated retinoblastoma phosphorylation is an early event in neuronal cell death.

Hamdane M, Bretteville A, Sambo AV, Schindowski K, Bégard S, Delacourte A, Bertrand P, Buée L.

J Cell Sci. 2005 Mar 15;118(Pt 6):1291-8. Epub 2005 Mar 1.

47.

Proteasome inhibition and Tau proteolysis: an unexpected regulation.

Delobel P, Leroy O, Hamdane M, Sambo AV, Delacourte A, Buée L.

FEBS Lett. 2005 Jan 3;579(1):1-5.

48.
49.

Stable-tau overexpression in human neuroblastoma cells: an open door for explaining neuronal death in tauopathies.

Delobel P, Mailliot C, Hamdane M, Sambo AV, Bégard S, Violleau A, Delacourte A, Buée L.

Ann N Y Acad Sci. 2003 Dec;1010:623-34. Review.

PMID:
15033802
50.

Neurofibrillary degeneration of the Alzheimer-type: an alternate pathway to neuronal apoptosis?

Hamdane M, Delobel P, Sambo AV, Smet C, Bégard S, Violleau A, Landrieu I, Delacourte A, Lippens G, Flament S, Buée L.

Biochem Pharmacol. 2003 Oct 15;66(8):1619-25. Review.

PMID:
14555242

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